Abstract: Provided are CCT5-binding molecules, including anti-CCT5 antibodies and antigen- binding fragments thereof such as heavy chain variable (VH) regions and single-chain antibody fragments, and conjugates comprising the anti-CCT5 binding molecules such as immunoconjugates and antibody-drug conjugates, and chimeric receptors comprising the anti-CCT5 binding molecules such as chimeric antigen receptors (CARs). In some embodiments, the anti-CCT5 antibodies or antigen-binding fragments thereof specifically bind to CCT5. Also provided are genetically engineered cells expressing the CARs or CCT5-binding molecules and uses thereof such as in adoptive cell therapy.

Abstract: The invention provides a pre-insulated duct having a length and comprising a tube having a foam layer. The pre-insulated duct has an interior face and an exterior face and a thickness defined as a distance between the interior face and the exterior face. The interior face of the pre-insulated duct bounds an airflow space. In the present group of embodiments, the pre-insulated duct has a mounting rail system extending along the length of the pre-insulated duct. The mounting rail system includes at least one mounting rail, and preferably a plurality of mounting rails, positioned on (e.g., positioned on an exterior of) the pre-insulated duct.

Abstract: Provided herein is a method for removing a chemical stain from a dental surface or inhibiting chemical staining of a dental surface, comprising contacting the dental surface with an oral care composition comprising zinc phosphate and an orally acceptable carrier.

Abstract: Provided herein is a method for removing a chemical stain from a dental surface or inhibiting chemical staining of a dental surface, comprising contacting the dental surface with an oral care composition comprising zinc phosphate and an orally acceptable carrier.

Abstract: Described herein are aqueous oral care compositions comprising (a) an effective amount of a basic amino acid in free or orally acceptable salt form; and (b) a polymer system comprising (i) a cellulosic polymer, (ii) a gum polymer, and (iii) a polyacrylate polymer or co-polymer; and methods of making and using the same.

Abstract: This invention relates to a dual phase mouthwash comprising a hydrophilic phase, a hydrophobic phase, and a hydrotrope, wherein the hydrophobic phase comprises coconut oil, as well as to methods of using and of making such compositions.

Abstract: The invention provides a pre-insulated duct having a length and comprising a tube having a foam layer. The pre-insulated duct has an interior face and an exterior face and a thickness defined as a distance between the interior face and the exterior face. The interior face of the pre-insulated duct bounds an airflow space. In the present group of embodiments, the pre-insulated duct has a mounting rail system extending along the length of the pre-insulated duct. The mounting rail system includes at least one mounting rail, and preferably a plurality of mounting rails, positioned on (e.g., positioned on an exterior of) the pre-insulated duct.

Abstract: An oral care composition comprising zinc phosphate and stannous fluoride.

Abstract: An oral care composition comprising zinc phosphate and stannous fluoride.

Abstract: Described herein are oral care compositions comprising a zinc ion source, a fluoride ion source, and a basic amino acid; along with methods of making and using the same.

Abstract: Provided herein is a method for removing a chemical stain from a dental surface or inhibiting chemical staining of a dental surface, comprising contacting the dental surface with an oral care composition comprising zinc phosphate and an orally acceptable carrier.

Abstract: Provided herein is a method of quantifying dentin tubules in a dentin surface. Also provided are uses of the method and a computer program which performs the method.

Abstract: This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an anionic surfactant, and to methods of using and of making such compositions.

Abstract: Provided herein is a method for removing a chemical stain from a dental surface or inhibiting chemical staining of a dental surface, comprising contacting the dental surface with an oral care composition comprising zinc phosphate and an orally acceptable carrier.

Abstract: An oral care composition comprising at least one metal phosphate chosen from stannous phosphate, magnesium phosphate or aluminum phosphate; and at least one fluoride ion source. The at least one phosphate is added to the oral care composition as a preformed salt. Methods of administering the oral care composition to a subject are also disclosed.

Abstract: An oral care composition is disclosed. The composition comprises zinc phosphate and a silicate compound comprising a metallic element that in cationic form is capable of reducing tooth enamel erosion. The zinc phosphate is added to the oral care composition as a preformed salt. Methods of administering the oral care compositions to subjects in need thereof are also disclosed.

Abstract: An oral care composition comprises zinc phosphate and at least one anti-microbial agent chosen from engenol, isoeugenol, eugenol acetate and isoeugenol acetate. The zinc phosphate is added to the oral care composition as a preformed salt.

Abstract: Described herein, are compositions comprising an effective amount of a basic amino acid in free or salt form, and a water soluble strontium salt; and methods of making and using the same.

Abstract: An oral care composition comprising zinc phosphate and stannous fluoride.

Abstract: This invention relates to a dual phase mouthwash comprising a hydrophilic phase, a hydrophobic phase, and a hydrotrope, wherein the hydrophobic phase comprises coconut oil, as well as to methods of using and of making such compositions.