Abstract: A non-crosslinked polymeric heat shrink tubing including poly (ether-block-amide) (PEBA) and methods for making such non-crosslinked polymeric heat shrink tubing is provided. The non-crosslinked PEBA heat shrink tubing disclosed herein finds application, e.g., as a processing aid and final component in the manufacture of catheters and other medical devices. When utilized as an outer jacket of a laser-cut hypotube, the non-crosslinked PEBA heat shrink tubing can advantageously not considerably infiltrate the kerfs of the underlying laser-cut hypotube.

Abstract: Systems, methods and devices are provided for registering DNS hostnames of Internet host devices for very large domain zones (VLZ) stored on a DNS server on a network, including setting a pseudo-zone as the VLZ, intercepting DNS updates to the pseudo-zone, mapping the entries in the pseudo-zone into a hierarchy of real parent zones and sub-zones using a mapping formula, and translating DNS updates to the pseudo-zone from an original fully qualified domain name (FQDN) into a at least one new FQDNs and adding the at least one new FQDNs to an authoritative DNS Server.

Abstract: Systems, methods, architectures, mechanisms or apparatus for streaming content toward client devices, comprising a content delivery system configured to automatically ingest content asset packages and publish identifying data associated with content assets encrypted and stored therein at a content delivery network (CDN), a virtualized Digital Rights Management (DRM) platform configured to provide content encryption keys to the content delivery system and to authorized client devices, and a virtualized services platform configured to interact with client devices to authenticate client devices, receive client device content requests, and cause the CDN to transmit requested content to an authorized client device.

Abstract: An optical lens casting gasket, wafer, and system and method that provides for more efficient formation of optical lenses employing optically functional wafers.

Abstract: A mass spectrometer is disclosed comprising a rotatable isolation valve 1 having a curved, spherical, cylindrical or concave portion. At least a portion of an ion guide 2 is positioned so as to extend within a swept volume of the isolation valve 1 enabling the ion guide 2 to be positioned close to a second downstream ion guide 3 and for ions to be transmitted from the first 2 ion guide to the second ion guide 3 with high ion transmission efficiency.

Abstract: Prostheses and methods are described for stabilizing dysfunctional sacroiliac (SI) joints. The prostheses are sized and configured to be press-fit into surgically created pilot SI joint openings in dysfunctional SI joint structures. The prostheses have a pontoon shape with opposed elongated partially cylindrical sections connected by a bridge section. The bridge section can have various shapes, such as an offset, arched structure, to accommodate the delivery and/or positioning of a primary or supplemental support member or device between the first and second elongated sections, such as a sacral-alar iliac (S2AI) screw or surgical dowel member.

Abstract: The present invention relates to pharmaceutical compositions and methods useful for the treatment of dermatological disorders, and in particular acne vulgaris and skin pigmentation disorders. Pharmaceutical compositions comprising one or more arginine, salicylic acid and/or azelaic acid that are useful for the treatment of dermatological diseases and the symptoms and underlying causes of such dermatological diseases are also disclosed.

Abstract: Air cleaner assemblies, components, and features are described. The features can be used to provide that the air cleaner assembly cannot be fully closed, even if a cartridge is nested therein, and appears to be sealed, unless that cartridge is a proper one for the system of concern. The effect is to prevent an inappropriate cartridge, that does not properly seal, from being inadvertently installed in the assembly.

Abstract: Disclosed herein are improved methods for bonding textiles using an adhesive composition.

Abstract: A method of heap leaching a metal from a mined ore that contains a metal sulfide-containing material, such as a copper sulfide-containing mineral. The method forms a heap of the mined ore or extends an existing heap by adding the mined ore to the heap. The method also leaches the metal from the mined ore in the heap with an acidic leach liquor and produces a pregnant leach liquor containing the metal in solution. Pyrite that is already in the mined ore generates acid and heat that facilitates leaching metal from the mined ore. The mined ore may be run-of-mine (ROM) ore that is transferred directly from the mine to the heap without changing the size of ore particles in the mined ore.

Abstract: This invention relates to compounds useful as lysyl oxidase (LOX) and lysyl oxidase-like (LOXL) family member (LOXL1, LOXL2, LOXL3, LOXL4) inhibitors. In addition there are contemplated pharmaceutical compositions comprising the compounds and the use of the compounds in the treatment of conditions mediated by LOX and LOXL, for example cancer. In particular a LOX inhibitor such as the present compounds may be for use in the treatment of a cancer associated with EGFR. The present invention also contemplates the identification of biomarkers that predict responsiveness to a LOX inhibitor.

Abstract: Prostheses and methods are described for stabilizing dysfunctional sacroiliac (SI) joints. The prostheses are sized and configured to be press-fit into surgically created pilot SI joint openings in dysfunctional SI joint structures. The prostheses have a pontoon shape with opposed elongated partially cylindrical sections connected by a bridge section. The bridge section can have various shapes, such as an offset, arched structure, to accommodate the delivery and/or positioning of a primary or supplemental support member or device between the first and second elongated sections, such as a sacral-alar iliac (S2AI) screw or surgical dowel member.

Abstract: A non-crosslinked polymeric heat shrink tubing including poly(ether-block-amide) (PEBA) and methods for making such non-crosslinked polymeric heat shrink tubing is provided. The non-crosslinked PEBA heat shrink tubing disclosed herein finds application, e.g., as a processing aid and final component in the manufacture of catheters and other medical devices.

Abstract: The present disclosure relates to ejector mechanisms and devices for generating a directed stream of droplets, as well as improved methods for delivering an ejected stream of droplets to a target. The device and methods may be useful for the delivery of fluid for ophthalmic, topical, oral, nasal, or pulmonary use, more particularly, for use in the delivery of ophthalmic fluid to the eye. Certain aspects of the disclosure relate to devices and methods for the delivery of a therapeutically effective low dosage volume medicament composition to a target, e.g., by controlling charge, droplet size and/or droplet deposit parameters of the medicament composition.

Abstract: An ejector device for ejecting droplets of fluid onto a surface includes an ejector mechanism attached to a fluid reservoir through a fluid loading plate that is configured to pierce the reservoir and channel the fluid to a rear surface of the ejector mechanism by capillary action. The ejector mechanism may have a centro-symmetric configuration with a lead free piezo actuator and may be covered by an auto-closing cover.

Abstract: Disclosed herein are improved adhesive compositions for bonding textiles and methods of producing the same.

Abstract: Disclosed are systems and methods for network configuration management systems and methods. In some embodiments, the discloses systems and methods may involve receiving data from one or more nodes within a particular network. The data may include, for example, topology, telemetry, geographical, and other data relating to the nodes, the network, and/or the functionality of the nodes or network. Once received, such data may be cleaned and processing may be performed on the data. Such processing may involve clustering the data into groups based on various parameters and performing forecasting on the data to determine future usage rates and capacity information, for example. The clustering and forecasting results may be fed to a rules engine and/or an optimization engine, which may then determine appropriate actions to take on the network (e.g., changes to various nodes in terms of technology and/or number of nodes).

Abstract: This disclosure relates to a lead frame assembly for a semiconductor device, a semiconductor device and an associated method of manufacture. The lead frame assembly includes a die attach structure and a clip frame structure. The clip frame structure includes a die connection portion configured to contact a contact terminal on a top side of the semiconductor die; and a continuous lead portion extending along the die connection portion. The continuous lead portion is integrally formed with the die connection portion.

Abstract: A set of hinges (1) that allow a user to open and close a set of removable rigid rooftop panels (5, 6) for a vehicle having a hardtop cover, such as a Jeep or sport utility vehicle, without being required to fully remove and store the rigid roof panels. The hinges may be locked in an open position using one or more hasps (24) integrated into the hinges.

Abstract: The present invention relates to a compound of formula (I). It also relates to a pharmaceutical composition comprising at least one compound of formula (I) and at least one pharmaceutically acceptable support. Finally, it relates to the use of such a compound as a medicine, preferably in the treatment of a nervous and/or respiratory failure due to intoxication with at least one organophosphorous nerve agent; in the treatment of neurological diseases such as Alzheimer's disease; and/or in the treatment of cancer.