Abstract: Air cleaner assemblies, components, and features are described. The features can be used to provide that the air cleaner assembly cannot be fully closed, even if a cartridge is nested therein, and appears to be scaled, unless that cartridge is a proper one for the system of concern. The effect is to prevent an inappropriate cartridge, that does not properly seal, from being inadvertently installed in the assembly.

Abstract: Provided herein are systems and methods for storing digital information by assembling an identifier nucleic acid molecule from at least a first component nucleic acid molecule and a second component nucleic acid molecule. The system may include a first printhead configured to dispense a first droplet of a first solution comprising the first component nucleic acid molecule onto a coordinate on a substrate, and a second printhead configured to dispense a second droplet of a second solution comprising the second component nucleic acid molecule onto the coordinate on the substrate, such that the first and second component nucleic acid molecules are collocated on the substrate. The system may include a finisher that dispenses a reaction mix onto the coordinate on the substrate to physically link the first and second component nucleic acid molecules, provides a condition necessary to physically link the first and second component nucleic acid molecules, or both.

Abstract: The present invention relates to a compound of formula (I), or one of its pharmaceutically acceptable salts: (I) wherein R1, R2 and —X—Y— have specific definitions. It also relates to the use of such a compound in therapy; and to a process for preparing it.

Abstract: A surgical access assembly includes a housing, a tubular member, and a valve assembly. The tubular member extends from the housing. The valve assembly is positioned in the housing and includes a centering mechanism, a guard assembly disposed on a first side of the centering mechanism, and an instrument seal disposed on a second side of the centering mechanism. The instrument seal including petals that are arrange in an overlapping arrangement.

Abstract: The invention relates to a pressure hull for human occupancy, which is manufactured using an additive manufacturing process. This results in increased structural integrity and safety for the occupants of the pressure hull.

Abstract: A hull for deployment as an underwater habitable vessel is described. The hull has at least two hull wall modules connected in series to enclose an interior volume of the underwater habitable vessel. The interior volume is bounded by the hull wall modules. There is also provided a kit of parts for a hull of an underwater habitable vessel. The kit comprises at least two hull wall modules configured to be connected in series to enclose an interior volume of the underwater habitable vessel. The interior volume is bounded by the hull wall modules when connected.

Abstract: A reel includes a core having a first end region, a first flange, a first hub member, and a first bonded joint connecting the first hub member to the first end region of the core. The first bonded joint includes a first susceptor material arranged between the first hub member and the first end region of the core. The first hub member and the first end region of the core are bonded together around the first susceptor material in such a way that the first flange is interposed between the first hub member and the first end region of the core.

Abstract: Disclosed herein are monomaterial garments and seam tapes that may be recyclable and methods of producing the same.

Abstract: A kit for forming a reel includes a core, at least a first flange and a second flange. The core has at least a first section and a second section, each forming first cylinders between a first edge and a second edge. The first edge of the first section includes a first lateral protrusion extending therefrom, which has a detent. The second section includes a first receiver configured to receive the first lateral protrusion and engage the detent via a retention structure to at least in part couple the first section to the second section. At least one of the first lateral protrusion and the first receiver is elastically deformable. The first flange can be disposed at a first axial end of the core, and the second flange can be disposed at a second axial end of the core.

Abstract: Prostheses and methods are described for stabilizing dysfunctional sacroiliac (SI) joints. The prostheses are sized and configured to be press-fit into surgically created pilot SI joint openings in dysfunctional SI joint structures. The prostheses have a pontoon shape with opposed elongated partially cylindrical sections connected by a bridge section. The bridge section can have various shapes, such as a planar-shaped structure, to accommodate the delivery and/or positioning of a primary or supplemental support member or device between the first and second elongated sections, such as a sacral-alar iliac (S2AI) screw or surgical dowel member.

Abstract: A reel includes a core, a first flange affixed to a first end of the core, a second flange affixed to a second opposite end of the core, and a first bonded joint connecting the first flange to the core. The first bonded joint includes a first susceptor material arranged between the first flange and the first end of the core, and the first flange and the first end of the core are bonded around the first susceptor material.

Abstract: Prostheses and methods are described for stabilizing dysfunctional sacroiliac (SI) joints. The prostheses are sized and configured to be press-fit into surgically created pilot SI joint openings in dysfunctional SI joint structures. The prostheses have a pontoon shape with opposed elongated partially cylindrical sections connected by a bridge section. The bridge section can have various shapes, such as an offset, arched structure, to accommodate the delivery and/or positioning of a primary or supplemental support member or device between the first and second elongated sections, such as a sacral-alar iliac (S2AI) screw or surgical dowel member.

Abstract: Prostheses and methods are described for stabilizing dysfunctional sacroiliac (SI) joints. The prostheses are sized and configured to be press-fit into surgically created pilot SI joint openings in dysfunctional SI joint structures. The prostheses have a pontoon shape with opposed elongated partially cylindrical sections connected by a bridge section. The bridge section can have various shapes, such as an offset, arched structure, to accommodate the delivery and/or positioning of a primary or supplemental support member or device between the first and second elongated sections, such as a sacral-alar iliac (S2AI) screw or surgical dowel member.

Abstract: The present invention relates to pharmaceutical compositions and methods useful for the treatment of dermatological disorders, and in particular acne vulgaris and skin pigmentation disorders. Pharmaceutical compositions comprising one or more arginine, salicylic acid and/or azelaic acid that are useful for the treatment of dermatological diseases and the symptoms and underlying causes of such dermatological diseases are also disclosed.

Abstract: Disclosed herein are improved methods for bonding textiles using an adhesive composition.

Abstract: Prostheses and methods are described for stabilizing dysfunctional sacroiliac (SI) joints. The prostheses are sized and configured to be press-fit into surgically created pilot SI joint openings in dysfunctional SI joint structures. The prostheses have a pontoon shape with opposed elongated partially cylindrical sections connected by a bridge section. The bridge section can have various shapes, such as an offset, arched structure, to accommodate the delivery and/or positioning of a primary or supplemental support member or device between the first and second elongated sections, such as a sacral-alar iliac (S2AI) screw or surgical dowel member.

Abstract: The present disclosure relates to ejector mechanisms and devices for generating a directed stream of droplets, as well as improved methods for delivering an ejected stream of droplets to a target. The device and methods may be useful for the delivery of fluid for ophthalmic, topical, oral, nasal, or pulmonary use, more particularly, for use in the delivery of ophthalmic fluid to the eye. Certain aspects of the disclosure relate to devices and methods for the delivery of a therapeutically effective low dosage volume medicament composition to a target, e.g., by controlling charge, droplet size and/or droplet deposit parameters of the medicament composition.

Abstract: An ejector device for ejecting droplets of fluid onto a surface includes an ejector mechanism attached to a fluid reservoir through a fluid loading plate that is configured to pierce the reservoir and channel the fluid to a rear surface of the ejector mechanism by capillary action. The ejector mechanism may have a centro-symmetric configuration with a lead free piezo actuator and may be covered by an auto-closing cover.

Abstract: Disclosed herein are improved adhesive compositions for bonding textiles and methods of producing the same.

Abstract: Disclosed are systems and methods for network configuration management systems and methods. In some embodiments, the discloses systems and methods may involve receiving data from one or more nodes within a particular network. The data may include, for example, topology, telemetry, geographical, and other data relating to the nodes, the network, and/or the functionality of the nodes or network. Once received, such data may be cleaned and processing may be performed on the data. Such processing may involve clustering the data into groups based on various parameters and performing forecasting on the data to determine future usage rates and capacity information, for example. The clustering and forecasting results may be fed to a rules engine and/or an optimization engine, which may then determine appropriate actions to take on the network (e.g., changes to various nodes in terms of technology and/or number of nodes).