Abstract: A pulse width encoded switching power supply, which may be electrically connected to an electroluminescent (EL) material is described. The power supply exploits both mechanical and electronic resonance principles to provide maximum emission from EL phosphor crystals using an LC tank circuit power supply design at specific frequency to maximize photon emission. Other possible applications are also described.

Abstract: A semiconductor structure includes a semiconductor layer that is passivated with an aluminum-silicon nitride layer. When the semiconductor layer in particular comprises a III-V semiconductor material such as a group III nitride semiconductor material or a gallium nitride semiconductor material, the aluminum-silicon nitride material provides a superior passivation in comparison with a silicon nitride material.

Abstract: A chemical vapor deposition method for forming an aluminum-silicon nitride layer upon a substrate uses an aluminum precursor, a silicon precursor and a nitrogen precursor under chemical vapor deposition conditions to deposit the aluminum-silicon nitride layer upon the substrate. The aluminum-silicon nitride layer has an index of refraction interposed between silicon nitride and aluminum nitride. The aluminum-silicon nitride layer also has a bandgap from about 4.5 to about 6 eV and a permittivity from about 6×10?-11 to about 8×10?-11 F/m. The aluminum-silicon nitride layer may be further thermally annealed to reduce a hydrogen content of the aluminum-silicon nitride layer.

Abstract: A method for fabricating a semiconductor structure includes forming a semiconductor layer over a substrate and forming an aluminum-silicon nitride layer upon the semiconductor layer. When the semiconductor layer in particular comprises a III-V semiconductor material such as a group III nitride semiconductor material or a gallium nitride semiconductor material, the aluminum-silicon nitride material provides a superior passivation in comparison with a silicon nitride material.

Abstract: A method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use and a device for droplet ejection includes a fluid delivery system capable of delivering a defined volume of the fluid in the form of droplets having properties that afford adequate and repeatable high percentage deposition upon application. The method and device include a housing, a reservoir disposed within the housing for receiving a volume of fluid, an ejector mechanism configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns, the stream of droplets having low entrained airflow such that the stream of droplets deposit on the eye of the subject during use.

Abstract: The disclosure relates to medical databases, remote monitoring, diagnosis and treatment systems and methods. In one particular embodiment, a system for remote monitoring, diagnosis, or treatment of eye conditions, disorders and diseases is provided. This method generally includes administering a stream of droplets to the eye of a subject from an ejector device, and storing data related to the administration in a memory of the ejector device. The data may then be monitored and analyzed.

Abstract: A system and method for creating a buffer solution having a desired pH value is disclosed. The method uses two known buffer solutions, each with predetermined pH values, and determines a mathematical relationship which defines the amount of each known buffer solution needed to create the buffer solution with the desired pH. This method can then be used to create one or more denaturation graphs, which demonstrate the stability of a protein at a given pH level.

Abstract: A system for automatically creating a denaturation curve is disclosed. In accordance with certain embodiments, a movement system including a unit having a plurality of cannulas is used. The cannulas are in fluid communication with a fluid system, which allows the cannulas to draw in and dispense fluid. A measurement system is included which draws fluid from a well into a detector to determine a characteristic of the fluid. A controller is used to control these systems and also to create a denaturation graph from the measured characteristics. In another embodiment, a plurality of formulations may be created using the system.

Abstract: A system and method for creating a plurality of denaturation curves is disclosed. In accordance with certain embodiments, one variable, such as salt content, pH or another parameter, is varied to create a plurality of different buffer solutions. Each is then used to create a denaturation graph. The plurality of denaturation graphs allows analysis of the effect of that variable on protein stability.

Abstract: A system and method for determining the dissociation constant for a particular ligand is disclosed. In accordance with certain embodiments, the method creates a chemical denaturation curve of a protein in the absence of the ligand. A particular point is selected from this curve, such as the point at which 90% of the protein is unfolded. The molarity of chemical denaturant is determined for this selected point. A one point test is then performed for the protein with a predetermined concentration of the particular ligand. The fraction of protein which is unfolded at this point is then used to determine the dissociation constant for the ligand. This constant is used to quickly determine whether a particular ligard is well suited to be considered a potential drug candidate against that protein target.

Abstract: A method includes executing a hypervisor (165) with computing hardware (105) to implement a virtual machine (175); responsive to detecting a removable storage medium (115) communicatively coupled to the computing hardware (105), executing a virtualized migration control appliance (180) through the hypervisor (165) separate from the virtual machine (175); and blocking the virtual machine (175) from accessing data (185) stored by the removable storage medium (115) with the virtualized migration control appliance (180) if at least one governing policy prohibits the virtual machine (175) from accessing the data (185).

Abstract: A device for connecting a soccer net to the horizontal crossbar of a soccer goal eight feet above the ground without using a ladder includes a resilient clip having an inner surface which is shaped and dimensioned to receive the horizontal crossbar and a line long enough to be thrown over the crossbar and hang down low enough to be reached and pulled down. The clip is attached to the edge cord of the net. The line is then thrown over the crossbar and pulled down raising the clip and net to the crossbar until the mouth of the clip is facing downward on the top of the crossbar. The line and net are then pulled down simultaneously forcing the mouth of the resilient clip to open, receive, and clamp on the horizontal cross bar. Conversely, when the net is to be removed, the line is thrown over the crossbar in the opposite direction and the line is pulled down until the clip is rotated until the mouth of the clip is facing upward on the crossbar.

Abstract: An LED edge-lit sign comprises a transparent light panel, an image-carrying sheet in front of the light panel and a reflective back plate behind the light panel. The image to be displayed is printed onto the image-carrying sheet and a translucent layer of white ink is uniformly applied over the printed image. The result is uniform and effective back lighting of the image. A transparent window may be provided to view a changeable display therethrough.

Abstract: The invention provides for compounds having the structure according to the formula I wherein: X is a carbon or nitrogen atom; Ar is phenyl or heteroaromatic ring; R1 is hydrogen, halogen, CN or (1C-4C)alkyl; R2 is hydrogen, halogen or optionally fluorinated (1C-3C)alkoxy; R3 and R5 are independently hydrogen, optionally halogenated (1C-4C)alkyl, optionally halogenated (1C-4C)alkoxy, optionally halogenated aryl(1C-4C)alkoxy, optionally halogenated (1C-4C)alkenyl or hydroxylmethyl; R4 is hydrogen, halogen, optionally halogenated (1C-4C)alkoxy or optionally halogenated aryl(1C-4C)alkoxy; R6 is hydrogen, benzyl, optionally substituted with one or more halogens or (1C-4C)alkyl, or R6 is optionally halogenated (1C-4C)alkyl; each R7 independently is hydrogen, halogen, optionally halogenated (1C-4C)alkyl or optionally halogenated (1C-4C)alkoxy and pharmaceutically suitable acid addition salts thereof for use as glucocorticoid receptor modulators, in particular for treatment of central nervous system disorders.

Abstract: A library of audio segments of a song is generated by receiving recorded tracks that include a complete performance of or a composition of unique portions and repetitive portions of the song, segmenting a select track into intervals, analyzing each interval to characterize the interval, comparing each interval with subsequent intervals of the select track to identify repetitive content in the song, identifying a select interval from a set of repeated intervals from the select track and storing the encoded representation of each of the select intervals from a corresponding set of repeated intervals in the library. Intervals can be characterized by frequency analysis, cross-correlation of a waveform, by a trained ear or by analysis of a musical notation corresponding to the song. Intervals for compression can be based on beats, that is, the time for a designated note, notes, a measure, or multiple measures. One or more unique measures can be encoded for additional compression.

Abstract: A passenger vehicle safety system is provided which comprises a violation system, a warning system or an inside system. The violation system collects evidence of traffic violation occurring in a vicinity of a passenger vehicle. The warning system provides a warning to individuals outside and in the vicinity of the passenger vehicle. The intra-vehicle system collects images of persons inside, or in the vicinity of, the passenger vehicle, so as to allow the passenger vehicle's driver or one or more individuals located at a remote location, some distance from the passenger, to monitor activity in and around the passenger vehicle. Information captured by the inside system can be viewed in real time, as the information is being collected, or some time later, or both.

Abstract: An improved method and compositions for treating organic compounds present in soil, groundwater and other environments is disclosed. The method involves the use of a composition comprising a solid state, water soluble peroxygen compound and zero valent iron.

Abstract: The invention relates to a composite structure vessel and transportation system for liquefied gases and methods of manufacture. More specifically, the system provides a composite vessel for operative connection to a truck trailer system for transporting at least two gas products such as carbon dioxide and liquid nitrogen within the composite vessel at different times. The composite vessel includes an inner liner, a composite layer including a plurality of resin-impregnated fiber layers, a thermal insulation layer, and an outer protective layer.

Abstract: A distributed data processing system includes individual data processing units that automatically communicate with a centralised data management unit in response to information objects being received or accessed by the data processing units. Data associated with information objects is communicated to the data management unit, thereby facilitating the automatic management of the information objects within the system.

Abstract: Economical sunlight collection panels are constructed to minimize the cost to generate electricity from solar radiation. The panels use a plurality of fixed plastic linear lenses to collect sunlight over a wide arc of solar movement and concentrate the collected light onto a plurality of relatively expensive narrow strips of photovoltaic material. The photovoltaic strips are moved in an arculate path and maintained parallel to the lenses so that the lines of light concentrated by the lens remain on the strips and produce electricity over a wide portion of the sun's path across the sky, even though the area of the photovoltaic strips is minimized for economy.