Abstract: An instruction (or set of instructions) that can be included in a program to perform a ray tracing acceleration data structure traversal, with individual execution threads in a group of execution threads executing the program performing a traversal operation for a respective ray in a corresponding group of rays such that the group of rays performing the traversal operation together. The instruction(s), when executed by the execution threads in respect of a node of the ray tracing acceleration data structure, cause one or more rays from the group of plural rays that are performing the traversal operation together to be tested for intersection with the one or more volumes associated with the node being tested. A result of the ray-volume intersection testing can then be returned for the traversal operation.

Abstract: An example method includes determining, for a first outcome event, a first symbol set to display within a symbol-display-portion of a display of the machine; displaying, by the display for the first outcome event, the first symbol set; determining, by the machine for a second outcome event occurring after the first outcome event, a second symbol set to display within the symbol-display-portion of the display; determining, by the machine for the second outcome event, for each instance of the particular symbol in the first symbol set, a corresponding second symbol position in the symbol-display-portion of the display; and displaying, by the display for the second outcome event, each instance of the particular symbol in the first symbol set randomly selected for the first outcome event at the corresponding second symbol position and each symbol of the second symbol set within the symbol-display-portion of the display.

Abstract: An instruction (or set of instructions) that can be included in a program to perform a ray tracing acceleration data structure traversal, with individual execution threads in a group of execution threads executing the program performing a traversal operation for a respective ray in a corresponding group of rays such that the group of rays performing the traversal operation together. The instruction(s), when executed by the execution threads in respect of a node of the ray tracing acceleration data structure, cause one or more rays from the group of plural rays that are performing the traversal operation together to be tested for intersection with the one or more volumes associated with the node being tested. A result of the ray-volume intersection testing can then be returned for the traversal operation.

Abstract: A computer-implemented method is disclosed. The method includes: displaying, on a touch-sensitive display of an electronic device, an indicated value and an annulus having a base segment and a highlighted segment, wherein points along a circumference of the annulus are associated with values between a base amount and a maximum amount and wherein a size of the highlighted segment is based on the indicated value; receiving, via the touch-sensitive display, a first value-adjusting input comprising a tap operation; and in response to receiving the first value-adjusting input, adjusting at least one of the base amount or the maximum amount for causing a range of the annulus to be changed, wherein a proportion of the annulus represented by the highlighted segment corresponds to a proportion of the range represented by the indicated value.

Abstract: Methods and systems for intraoperatively determining alignment parameters of a spine during a spinal surgical procedure are disclosed herein. In some embodiments, a method of intraoperatively determining an alignment parameter of a spine during a surgical procedure includes receiving initial image data of the spine including multiple vertebrae and identifying a geometric feature associated with each vertebra in the initial image data. The geometric features each have a pose in the initial image data and characterize a three-dimensional (3D) shape of the associated vertebra. The method further comprises receiving intraoperative image data of the spine and registering the initial image data to the intraoperative image data. The method can then update the pose of each geometric feature based on the registration and the intraoperative image data, and determine the alignment parameter based on the updated poses of the geometric features associated with two or more of the vertebrae.

Abstract: Disclosed are method and apparatus for identifying biomarkers and in particular for identifying biomarkers for use in making clinical assessments, such as early diagnostic, diagnostic, disease stage, disease severity, disease subtype, response to therapy or prognostic assessments. In one particular example, the techniques are applied to allow assessments of patients suffering from, suspected of suffering from, or with clinical signs of SIRS (Systemic Inflammatory Response Syndrome) being either infection-negative SIRS or infection-positive SIRS.

Abstract: There is provided an instruction, or instructions, that can be included in a program to perform a ray tracing operation, with individual execution threads in a group of execution threads executing the program performing the ray tracing operation for a respective ray in a corresponding group of rays such that the group of rays performing the ray tracing operation together. The instruction(s), when executed by the execution threads will cause one or more rays from the group of plural rays to be tested for intersection with a set of primitives. A result of the ray-primitive intersection testing can then be returned for the traversal operation.

Abstract: An electrical power connector includes a connector housing having a slot at a mating end of the connector housing configured to receive a power distribution assembly. The electrical power connector includes power contacts received in the connector housing configured to be is coupled to a power distribution contact of the power distribution assembly. The electrical power connector includes a monitoring device having a monitoring circuit, a monitoring sensor coupled to the monitoring circuit, and a monitoring transmitter coupled to the monitoring circuit. The monitoring sensor is coupled to the power contact to monitor an operating characteristic of the power contact. The monitoring circuit receives sensor signals from the monitoring sensor and the monitoring transmitter transmits monitoring signals from the monitoring circuit based on the operating characteristic of the power contact to a monitoring network remote from the electrical power connector.

Abstract: Presented herein are dual-function surgical tools for insertion of implantable stimulating assemblies, such as intra-cochlear stimulating assemblies. In addition to facilitating intra-operative positioning of a stimulating assembly within a recipient (e.g., operating to guide the stimulating assembly of an implantable medical device into position), the surgical tool also includes a plurality of electrodes configured to apply an electroporation electrical field to a recipient's nerve cells to enable introduction of treatment substance into the nerve cells.

Abstract: Disclosed are methods, apparatus, kits and compositions for determining the absence of a systemic bacterial infection (sepsis) in patients, particularly ones presenting to hospital emergency departments (ED) as outpatients, by measurement of the host immune response using peripheral blood. The are methods, apparatus, kits and compositions can be used in mammals for diagnosing, making treatment decisions, determining the next procedure or diagnostic test, or management of patients suspected of having an infection, including those presenting with fever or other signs of systemic inflammation. More particularly, peripheral blood RNA and protein biomarkers are disclosed that are useful for distinguishing between the host immune response to bacteria compared to the host immune response to other causes of systemic inflammation including trauma, burns, autoimmune disease, asthma, anaphylaxis, arthritis, obesity and viral infections.

Abstract: Disclosed is a method for treating or inhibiting the development of severe sepsis in a subject based on measuring the level of a defensin alpha 4 (DEFA4) polynucleotide expression product.

Abstract: Disclosed are compositions, methods and apparatus for diagnosing and/or monitoring a virus-associated systemic inflammation by measurement of a host immune response. The invention can be used for diagnosis including early diagnosis, monitoring, making treatment decisions, or management of subjects suspected of having systemic inflammation associated with an infection. More particularly, the present disclosure relates to peripheral blood RNA and protein biomarkers that are useful for specifically distinguishing between the host systemic immune response to viruses as compared to the host immune response to other causes of systemic inflammation.

Abstract: Presented herein are dual-function surgical tools for insertion of implantable stimulating assemblies, such as intra-cochlear stimulating assemblies. In addition to facilitating intra-operative positioning of a stimulating assembly within a recipient (e.g., operating to guide the stimulating assembly of an implantable medical device into position), the surgical tool also includes a plurality of electrodes configured to apply an electroporation electrical field to a recipient's nerve cells to enable introduction of treatment substance into the nerve cells.

Abstract: Presented herein are techniques for increasing sensitivity of a hearing prosthesis to sound signals received from the “side” of a recipient. The sensitivity of the hearing prosthesis to sound signals received from the side of a recipient is provided by a spatial pre-filter that is configured to use a primary reference signal (i.e., a first directional signal) and a side reference signal (i.e., a second directional signal having at least one null directed to the side of the recipient) to calculate a side gain mask. The side gain mask includes gains for each of a plurality of frequency channels associated with the received sound signals.

Abstract: A wireless sensor preferably has a case which is intrinsically safe and has no exposed parts which can become not intrinsically safe due to the passage of time or through contact with chemicals typically encountered in a location where the wireless sensor is used. It preferably has no integral visual display other than lights, and it preferably includes at least one signal light. The sensor preferably includes a wireless transceiver for allowing remote read and remote control of the sensor. The sensor preferably includes piezoelectric pressure detectors for allowing a user to locally interact with the sensor by pressing on the case. Data can be automatically harvested from the sensors by a portable electronic data-retrieving device which is usually geographically remote from the sensors when the portable electronic data-retrieving device and the sensors are in range of a wireless system which allows them to communicate when they are geographically proximate each other.

Abstract: Presented herein are techniques for increasing sensitivity of a hearing prosthesis to sound signals received from the “side” of a recipient. The sensitivity of the hearing prosthesis to sound signals received from the side of a recipient is provided by a spatial pre-filter that is configured to use a primary reference signal (i.e., a first directional signal) and a side reference signal (i.e., a second directional signal having at least one null directed to the side of the recipient) to calculate a side gain mask. The side gain mask includes gains for each of a plurality of frequency channels associated with the received sound signals.

Abstract: Disclosed is a fence panel including a rectangular mesh body which includes a plurality of lengths of razor wire arranged to form a plurality of diamond-shaped mesh apertures, each aperture having a major axis of length L and a minor axis of length L/2, and wherein the lengths of razor wire are fixed to one another at respective junctions, wherein L?200 mm.

Abstract: Disclosed are substituted aminoquinoline and aminopyridine compounds and their use as bacterial nitric oxide synthase (bNOS) inhibitors. Also disclosed are pharmaceutical compositions comprising the compounds, and methods of using the compounds and pharmaceutical compositions for treating a subject having or at risk for developing a disease or disorder that is associated with bNOS activity.

Abstract: An apparatus, comprising, a cochlear implant electrode array, and an implantable drug reservoir, wherein the apparatus is configured such that the drug reservoir is in fluid communication with the electrode array, and the drug reservoir is at least substantially located in a middle ear space when the cochlear implant electrode array is fully implanted in a recipient.