Abstract: Capsaicin compositions and methods for enhancing hydrophobicity of a molecule useful for pharmaceutical applications, including: (1) a prodrug using a linker such as a carbamate between capsaicin with other structures in order to optimize kinetic control of capsaicin cleavage; (2) a prodrug using a linker such as an unsaturated carboxylic ester between capsaicin with other structures in order to optimize kinetic control of capsaicin cleavage; (3) esters of long-chain fatty acids and capsaicin where hydroxyl groups provide handles for attachment of additional capsaicin molecules; and (4) the use of carboxylic acid diesters to increase overall hydrophobicity of two or more covalently-linked capsaicin molecules. Formulations of palmitated esters of capsaicin are also described, which are designed to enhance hydrophobicity of a molecule useful for pharmaceutical applications, for example to provide compounded mixtures designed to optimize analgesic efficacy.

Abstract: A tuneable expiration positive airway pressure (TEPAP) apparatus (10) comprises an entrainment valve (12) and a module (14), fluidly coupled with an outlet port (60) of the entrainment valve, for tuning an inspiration-to-expiration pressure transition of the breath cycle. The entrainment valve (12) includes a housing (56), an upstream inlet port (58), a downstream outlet port (60), and a valve (62). The valve (62) enables inspiration airflow between an exterior the housing (56) and the inlet port (58) during inspiration and prevents expiration airflow between the inlet port (58) and the exterior of the housing (56) during expiration. The tuning module (14) facilitates at least one rate-of-change in pressure of the inspiration-to-expiration pressure transition that is non-instantaneous. The at least one non-instantaneous rate of change in pressure is selected from among different non-instantaneous rates-of-change in pressure of the inspiration-to-expiration pressure transition.

Abstract: An embodiment may receive observed data from a monitored system. The embodiment may receive a request to generate a contextual report based on the observed data. The embodiment may identify a relevant persona corresponding to the request based on a series of linguistic cues. The embodiment may identify a list of suitable keywords based on the identified relevant persona. The embodiment may generate a persona-based contextual report for the observed data based on the identified relevant persona and the list of suitable keywords.

Abstract: An embodiment for generating person-based contextual reports is provided. The embodiment may receive observed data from a monitored system. The embodiment may receive a request to generate a contextual report based on the observed data. The embodiment may identify a relevant persona corresponding to the request based on a series of linguistic cues. The embodiment may identify a list of suitable keywords based on the identified relevant persona. The embodiment may generate a persona-based contextual report for the observed data based on the identified relevant persona and the list of suitable keywords.

Abstract: There is provided an apparatus for delivering a flow of gas having a controller, a housing defining a gasflow passage, a motor with an impeller to deliver gas through the gasflow passage, and a flexible printed circuit electrically connected to the motor for electrically connecting the motor to the controller. There is also provided an apparatus for delivering a flow of gas having a housing defining a gasflow passage. The gas flowing through the gasflow passage is a high concentration oxygen gas. The apparatus has a motor with windings and an impeller to deliver gas through the gasflow passage, and an elastomeric shield to pneumatically isolate the windings from the gasflow passage.

Abstract: Unmanned vehicles may be terrestrial, aerial, nautical, or multi-mode. Unmanned vehicles may accomplish tasks by breaking out into sub-drones, re-grouping itself, changing form, or re-orienting its sensors.

Abstract: The present technology relates to copolymers of single ion conducting monomers and/or of neutral monomers, and relates to the methods of making them.

Abstract: Systems, devices and methods for optimising and managing distributed energy storage and flexibility resources on a localised and group aggregation basis, particularly around the determination, analysis and predictive learning of local data patterns, scoring availability for flexibility and risk profiles, to inform the optimisation of energy supply and behind the meter storage resources and local clusters of co-located or close resources within a community, low voltage network, feeder, neighbourhood or building. Said optimisation to involve scheduled, reactive and active management of data sources and local clusters of resources, for a range of goals such as price, energy supply, renewable leverage, asset value, constraint or risk management.

Abstract: Using an image analysis model within an image intended for distribution online, an image portion depicting personally identifiable information is identified, the personally identifiable information comprising image data usable to identify a specific individual. Using an online profile, a person depicted in the image portion is identified. A transaction is posted in a publicly-accessible distributed encrypted ledger, the transaction comprising an encrypted request to allow the image to be distributed online. According to a response to the request, the image portion is obfuscated, the obfuscating comprising altering data of the image portion, the altering making the image portion unusable to identify the person.

Abstract: This invention relates to connectors to be provided into fluid communication or engagement either directly with, or via a component to be associated with, a terminal end of a breathing conduit. In at least one embodiment, the connector comprises a body having a first end and a second end, and an internal lumen for the passage of gas between the ends. The first end engageable with a terminal end of a conduit or a component to be associated therewith. The second end engageable with another connector. An internal surface of the body at the second end comprises internal connection features for connection with another connector to be received internally therein. An external surface of the body comprises one or more external alignment feature(s) for aligning the connector or another connection into an aligned orientation for connection therebetween.

Abstract: A therapy system for treating a tissue site with negative-pressure therapy and/or fluid instillation therapy in response to information received from a diagnostic module is described. The therapy system may include a dressing, a negative-pressure source, a container, and a diagnostic module. The dressing be placed on the tissue site, and the negative-pressure source may be fluidly coupled to the dressing. The container may be fluidly coupled to the dressing and to the negative-pressure source to receive fluid from the tissue site. The diagnostic module may be exposed to gas associated with the fluid from the tissue site. The diagnostic module may comprise a sensor configured to detect a condition of the tissue site and to generate an output based on the detected condition. The sensor may be configured to detect a volatile organic compound. The diagnostic module may be positioned on the container.

Abstract: A system may include one or more sensors configured to acquire data associated with a driver of a vehicle and a processor. The processor may receive the data and determine whether the data is within a baseline data associated with expected behavior of the driver. The processor may then control one or more operations of the vehicle in response to the data being outside the baseline data.

Abstract: Unmanned vehicles can be terrestrial, aerial, nautical, or multi-mode. Unmanned vehicles may be used to survey a property in response to or in anticipation of a threat. For example, an unmanned vehicle may analyze information about the property and based on the information deter theft of items on the property.

Abstract: The present invention relates generally to systems, devices and methods for the efficient use of utilities, more particularly to the distribution and provision of electricity supply at appropriate voltages, monitoring and usage by end devices, and to facilitating consumers in changing their energy usage behaviour, and to adopt and easily install appropriate sustainable, energy efficient or renewable technologies. Said end devices typically including traditional electric, electronic and lighting appliances requiring AC or DC power provision or low voltage DC power via AC/DC converters.

Abstract: Aspects of the present disclosure relate generally to software development environments and, more particularly, to systems, computer program products, and methods of automating software development, security, and operations (DevSecOps). For example, a computer-implemented method includes receiving, by a processor, a plurality of infrastructure as code files specifying a configuration of a runtime environment for a deployable image of source code in a continuous integration and continuous delivery pipeline for a cloud platform; generating, by the processor, compliance code for at least one file of the plurality of infrastructure as code files; building, by the processor, the deployable image of the source code in the continuous integration and continuous delivery pipeline according to the configuration specified by the plurality of infrastructure as code files and the compliance code; and deploying, by the processor, an instance of the image in the runtime environment.

Abstract: This invention relates to connectors to be provided into fluid communication or engagement either directly with, or via a component to be associated with, a terminal end of a breathing conduit. In at least one embodiment, the connector comprises a body having a first end and a second end, and an internal lumen for the passage of gas between the ends. The first end engageable with a terminal end of a conduit or a component to be associated therewith. The second end engageable with another connector. An internal surface of the body at the second end comprises internal connection features for connection with another connector to be received internally therein. An external surface of the body comprises one or more external alignment feature(s) for aligning the connector or another connection into an aligned orientation for connection therebetween.

Abstract: A reduced pressure dressing for applying reduced pressure treatment to a tissue site includes an interface layer adapted to be positioned at the tissue site. An absorbent layer is in fluid communication with the interface layer to absorb liquid from at least one of the interface layer and the tissue site. A pump is in fluid communication with the absorbent layer to deliver a reduced pressure to the tissue site. A cover is positioned over the pump, the absorbent layer, and the interface layer to maintain the reduced pressure at the tissue site, and a liquid-air separator is positioned between the absorbent layer and the pump to inhibit liquid from entering the pump.

Abstract: A reduced pressure dressing for applying reduced pressure treatment to a tissue site includes an interface layer adapted to be positioned at the tissue site. An absorbent layer is in fluid communication with the interface layer to absorb liquid from at least one of the interface layer and the tissue site. A pump is in fluid communication with the absorbent layer to deliver a reduced pressure to the tissue site. A cover is positioned over the pump, the absorbent layer, and the interface layer to maintain the reduced pressure at the tissue site, and a liquid-air separator is positioned between the absorbent layer and the pump to inhibit liquid from entering the pump.

Abstract: Methods and systems are disclosed herein for automatically indicating, during display of video of an event, actions in event that could satisfy side-game scoring scenarios. This may be accomplished by a media application that generates a live video of an event and retrieves data relating to a current status of a side-game in which a user is participating. The media application determines that a next play of the event could affect an outcome of the side-game and, in response, determines a particular action within the event that could affect the outcome of the side-game. The media application generates for display, within the video, an overlay on top of a playing space of the event, the overlay indicating where the particular action would need to occur to affect the outcome of the side-game.

Abstract: Devices at a scene of a vehicular accident may be used to direct vehicle traffic in response to the vehicular accident. For example, a device associated with a structure at a location of the vehicular accident may analyze information about the accident scene and, based on the information, direct traffic near the accident scene.