Patents by Inventor Richard E. Jones

Richard E. Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190185462
    Abstract: The present invention is directed to substituted 5-trifluoromethyl oxadiazole compounds of generic formula (I) or a pharmaceutically acceptable salt thereof. In particular, the invention is directed to a class of aryl and heteroaryl substituted 5-trifluoromethyl oxadiazole compounds of formula I which may be useful as HDAC6 inhibitors for treating cellular proliferative diseases, including cancer, neurodegenerative diseases, such as schizophrenia and stroke, as well as other diseases.
    Type: Application
    Filed: June 19, 2017
    Publication date: June 20, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Abbas Walji, Richard Berger, Craig A. Stump, Kelly Ann S. Schlegel, James J. Mulhearn, Thomas J. Greshock, Deping Wang, Mark E. Fraley, Kristen G. Jones
  • Patent number: 9586430
    Abstract: Disclosed are various embodiments relating to verifying a printed work comprises a correct number of pages. Associated with a stack comprising one or more pages is an identifier that may be used to obtain an expected value for a physical characteristic of the pages in the stack. A sensor may then measure an actual value for the physical characteristic of the pages in the stack. Before binding the pages in the stack, the expected value may be compared to the actual value in order to verify the stack comprises the correct number of pages.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: March 7, 2017
    Assignee: Amazon Technologies, Inc.
    Inventors: Richard E. Jones, Jeffrey R. Raines, Jeffrey I. Coker, Scott W. Horoho, Brian E. Johnson
  • Patent number: 8998996
    Abstract: A modular knee prosthesis system includes a femoral component having a stem and a sleeve. The system is modular, and provides the surgeon with the option of distally offsetting the joint line by controlling the relative axial positions of the stem and the sleeve. Alternative options include providing sleeves with tapered bores of different diameters, providing a shim to be placed between the sleeve and the stem and providing the stems as adapters having different diameters.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 7, 2015
    Assignee: Depuy (Ireland)
    Inventors: Peter J James, Richard E Jones, Benjamin J Sordelet, Timothy G Vendrely, Stephanie M Wainscott
  • Publication number: 20140334900
    Abstract: Disclosed are various embodiments relating to verifying a printed work comprises a correct number of pages. Associated with a stack comprising one or more pages is an identifier that may be used to obtain an expected value for a physical characteristic of the pages in the stack. A sensor may then measure an actual value for the physical characteristic of the pages in the stack. Before binding the pages in the stack, the expected value may be compared to the actual value in order to verify the stack comprises the correct number of pages.
    Type: Application
    Filed: July 24, 2014
    Publication date: November 13, 2014
    Inventors: Richard E. Jones, Jeffrey R. Raines, Jeffrey I. Coker, Scott W. Horoho, Brian E. Johnson
  • Patent number: 8827616
    Abstract: Disclosed are various embodiments relating to verifying a printed work comprises a correct number of pages. Associated with a stack comprising one or more pages is an identifier that may be used to obtain an expected thickness of the pages in the stack. A sensor may then measure an actual thickness of the pages in the stack. Before binding the pages in the stack, the expected thickness of the stack may be compared to the actual thickness of the stack in order to verify the stack comprises the correct number of pages.
    Type: Grant
    Filed: November 23, 2011
    Date of Patent: September 9, 2014
    Assignee: Amazon Technologies, Inc.
    Inventors: Richard E. Jones, Jeffrey R. Raines, Jeffrey I. Coker, Scott W. Horoho, Brian E. Johnson
  • Publication number: 20140081409
    Abstract: A modular knee prosthesis system includes a femoral component having a stem and a sleeve. The system is modular, and provides the surgeon with the option of distally offsetting the joint line by controlling the relative axial positions of the stem and the sleeve. Alternative options include providing sleeves with tapered bores of different diameters, providing a shim to be placed between the sleeve and the stem and providing the stems as adapters having different diameters.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 20, 2014
    Inventors: PETER J JAMES, RICHARD E JONES, BENJAMIN J SORDELET, TIMOTHY G VENDRELY, STEPHANIE M WAINSCOTT
  • Patent number: 7172554
    Abstract: The present invention is directed to retractor instrumentation for total hip arthroplasty, and methods of using same. In one illustrative embodiment, the device comprises a body, a first pin coupled to the body, and a second pin coupled to said body, wherein at least a portion of said first and second pins are adapted to penetrate human bone. In a further illustrative embodiment, a retractor instrumentation set comprises a retractor device, a shaft that is adapted to be removably coupled to the retractor device, and an inserter that is adapted to be removably coupled to the shaft.
    Type: Grant
    Filed: June 4, 2004
    Date of Patent: February 6, 2007
    Assignee: Zimmer Technology, Inc.
    Inventors: Kenneth A. Gustke, Richard E. Jones, III, Donald W. Dye, Jr.
  • Publication number: 20040265376
    Abstract: Disclosed are orally deliverable pharmaceutical compositions of 2′-deoxy-2′-(fluoromethylene)cytidine (“FMdC”) and methods for providing enhanced bioavailability of FMdC in vivo.
    Type: Application
    Filed: April 19, 2004
    Publication date: December 30, 2004
    Inventor: Richard E. Jones
  • Publication number: 20040131646
    Abstract: Methods and compositions are provided for the treatment of a host suffering from a cellular proliferative disease. In the subject methods, antiproliferative agents are administered in a substantially non-aqueous gel delivery vehicle comprising at least one polar organic solvent in combination with one or more thickening agents. The subject methods and compositions provide for the enhanced efficacy of regionally or locally administered antiproliferative proliferative agents.
    Type: Application
    Filed: December 18, 2003
    Publication date: July 8, 2004
    Applicant: BioMedicines, Inc.
    Inventors: George Trager, Richard E. Jones
  • Publication number: 20040076679
    Abstract: Methods and compositions are provided for the treatment of a host suffering from a cellular proliferative disease. In the subject methods, antiproliferative agents are administered in a substantially non-aqueous gel delivery vehicle comprising at least one polar organic solvent in combination with one or more thickening agents. The subject methods and compositions provide for the enhanced efficacy of regionally or locally administered antiproliferative proliferative agents.
    Type: Application
    Filed: September 3, 2003
    Publication date: April 22, 2004
    Inventors: Richard E. Jones, Keith Washco, Kathleen V. Roskos, Richard Maskiewicz, George Trager
  • Patent number: 6699844
    Abstract: Methods of treating cancer by administration of FMdC followed by administration of a platinate are disclosed.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: March 2, 2004
    Assignee: Chiron Corporation
    Inventors: Richard E. Jones, Ning Y. Yu
  • Patent number: 6669958
    Abstract: Methods and compositions are provided for the treatment of a host suffering from a cellular proliferative diease. In the subject methods, antiproliferative agents are administered in a substantially non-aqueous gel delivery vehicle comprising at least one polar organic solvent in combination with one or more thickening agents. The subject methods and compositions provide for the enhanced efficacy of regionally or locally administered antiproliferative proliferative agents.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: December 30, 2003
    Assignee: BioMedicines, Inc.
    Inventors: George Trager, Richard E. Jones
  • Patent number: 6630168
    Abstract: Methods and compositions are provided for the treatment of a host suffering from a cellular proliferative disease. In the subject methods, antiproliferative agents are administered in a substantially non-aqueous gel delivery vehicle comprising at least one polar organic solvent in combination with one or more thickening agents. The subject methods and compositions provide for the enhanced efficacy of regionally or locally administered antiproliferative proliferative agents.
    Type: Grant
    Filed: February 20, 1997
    Date of Patent: October 7, 2003
    Assignee: BioMedicines, Inc.
    Inventors: Richard E. Jones, Keith Washco, Kathleen V. Roskos, Richard Maskiewicz, George Trager
  • Publication number: 20030171329
    Abstract: The present invention relates to tezacitabine ((E)-2′-fluoromethylene-2′-deoxycytidine) formulations which are stable for long periods of time. The present invention further relates to methods of formulating stable tezacitabine formulations.
    Type: Application
    Filed: February 12, 2003
    Publication date: September 11, 2003
    Inventors: Richard E. Jones, Mike T. Li, Andy Trammel, Christine M. Harrison-Bowman, Kimberly R. Shirley
  • Publication number: 20030109487
    Abstract: Methods of treating cancer by administration of FMdC followed by administration of a platinate are disclosed.
    Type: Application
    Filed: December 3, 2002
    Publication date: June 12, 2003
    Applicant: Matrix Pharmaceutical, Inc.
    Inventors: Richard E. Jones, Ning Y. Yu
  • Patent number: 6544962
    Abstract: Methods of treating cancer by administration of FMdC followed by administration of a platinate are disclosed.
    Type: Grant
    Filed: November 15, 2000
    Date of Patent: April 8, 2003
    Assignee: Matrix Pharmaceutical, Inc.
    Inventors: Richard E. Jones, Ning Y. Yu
  • Patent number: 6467797
    Abstract: A disclosed walker is a three sided framework allowing quick connect/disconnect to the frame of a conventional standard wheelchair. The walker is formed with a front and two side assemblies pivotally linked to the front assembly. When the walker is not connected to a wheelchair, the side assemblies and front assemblies pivot and collapse into a “z” pattern forming a flat, compact package. For connection to a wheelchair, the sides assemblies unfold perpendicularly to the front assembly, and are locked into place by a horizontal crossbar. U-shaped securing clips located at the rear ends of the walker's side assemblies, drop over and straddle horizontal frame members of the wheelchair tightly grasping the wheelchair's frame members. The stability of the walker/wheelchair combination is enhanced by outward bends of the front vertical sections of the walker which terminate in swivel caster supports.
    Type: Grant
    Filed: October 11, 2000
    Date of Patent: October 22, 2002
    Inventors: Stephen J Lofy, Richard E Jones
  • Publication number: 20020019365
    Abstract: Disclosed are orally deliverable pharmaceutical compositions of 2′-deoxy-2′-(fluoromethylene)cytidine (“FMdC”) and methods for providing enhanced bioavailability of FMdC in vivo.
    Type: Application
    Filed: May 31, 2001
    Publication date: February 14, 2002
    Inventor: Richard E. Jones
  • Patent number: 6224883
    Abstract: An improved diluent for the preparation of cisplatin suspensions from a lyophilized powder is provided. The diluent contains a pharmaceutically acceptable nonionic surfactant, which improves the accuracy and homogeneity of the therapeutic formulation. The suspension may be used directly, or may be used in preparing gel formulations for direct injection into a neoplastic lesion or surrounding tissue.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: May 1, 2001
    Assignee: Matrix Pharmaceutical, Inc.
    Inventors: Kathleen V. Roskos, Richard E. Jones, Richard Maskiewicz
  • Patent number: 6171342
    Abstract: A medical fastening system for a modular knee prosthesis system includes a femoral component having a first surface, a second surface, and an aperture extending therebetween. A modular adapter element has a first end that is mountable adjacent the first surface of the femoral component and a second, mating end that is engagable with a second prosthesis component. The system also includes a first bolt that mates the adapter element to the femoral component. Various connection options are possible to secure different components of the system to each other.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: January 9, 2001
    Assignee: Depuy Orthopaedics, Inc.
    Inventors: Michael J. O'Neil, Arnold Oyola, Dennis Sullivan, Amit Birla, John E. Slamin, Dennis P. Colleran, Stefan M. Gabriel, George B. Cipolletti, Richard E. Jones