Patents by Inventor Richard J. Wurtman

Richard J. Wurtman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4971998
    Abstract: Compositions useful in the treatment of disturbances of appetite, disturbances of mood, or both, associated with premenstrual syndrome, as well as methods of use therefor. The compositions include serotoninergic drugs, such as d-fenfluramine and fluoxetine.
    Type: Grant
    Filed: September 15, 1988
    Date of Patent: November 20, 1990
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard J. Wurtman, Judith J. Wurtman
  • Patent number: 4927853
    Abstract: Blood pressure is increased in a patient having a condition which effects rapid fixing of neurons in the sympathetic nervous system and low blood pressure by administering a mixture of (a) (1) phenylalanine or (2) a mixture of phenylalanine and tyrosine and (b) a drug which increases noradrenergic neurotransmission in the sympathetic nervous system.
    Type: Grant
    Filed: February 16, 1988
    Date of Patent: May 22, 1990
    Assignee: Massachusetts Institute of Technology
    Inventor: Richard J. Wurtman
  • Patent number: 4885312
    Abstract: Tyrosine or a tyrosine precursor is administered concomitantly with an indirect-acting sympathomimetic amine drug to increase the level of norepinephrine that can be released in sympathetic neuron synapses.
    Type: Grant
    Filed: December 29, 1986
    Date of Patent: December 5, 1989
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard J. Wurtman, Timothy J. Maher
  • Patent number: 4775665
    Abstract: Choline or a choline precursor is administered to a patient together with an amino acid which is a precursor to a neurotransmitter in order to give a synergistic result for the two components.
    Type: Grant
    Filed: September 24, 1987
    Date of Patent: October 4, 1988
    Assignee: Massachusetts Institute of Technology
    Inventor: Richard J. Wurtman
  • Patent number: 4745130
    Abstract: Blood pressure is increased in a patient having a condition which effects rapid firing of neurons in the sympathetic nervous system and low blood pressure by administering tyrosine to the patient. The tyrosine composition can be administered alone or concomitantly with a drug which increases noradrenergic neurotransmission in the sympathetic nervous system.
    Type: Grant
    Filed: October 29, 1984
    Date of Patent: May 17, 1988
    Assignee: Massachusetts Institute of Technology
    Inventor: Richard J. Wurtman
  • Patent number: 4737489
    Abstract: Choline or a choline precursor is administered to a patient together with an amino acid which is a precursor to a neurotransmitter in order to give a synergistic result for the two components.
    Type: Grant
    Filed: December 21, 1984
    Date of Patent: April 12, 1988
    Assignee: Massachusetts Institute of Technology
    Inventor: Richard J. Wurtman
  • Patent number: 4687763
    Abstract: A composition comprising tryptophan and melatonin with or without an insulin-releasing carbohydrate or melatonin and an insulin-releasing carbohydrate is administered to an animal in order to increase the levels or release of brain serotonin.
    Type: Grant
    Filed: February 25, 1985
    Date of Patent: August 18, 1987
    Assignee: Massachusetts Institute of Technology
    Inventor: Richard J. Wurtman
  • Patent number: 4673689
    Abstract: Tyrosine or a tyrosine precursor is administered concomitantly with an indirect-acting sympathomimetic amine drug to increase the level of norepinephrine that can be released in sympathetic neuron synapses.
    Type: Grant
    Filed: March 27, 1986
    Date of Patent: June 16, 1987
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard J. Wurtman, Timothy J. Maher
  • Patent number: 4649161
    Abstract: D-fenfluramine is administered to a human patient having seasonal depression or other forms of bipolar depression in order to alleviate or cure the depression.
    Type: Grant
    Filed: June 16, 1986
    Date of Patent: March 10, 1987
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard J. Wurtman, Judith J. Wurtman, Dermot O'Rourke
  • Patent number: 4636494
    Abstract: Choline or a natural or synthetic compound that dissociates to form choline is administered to a patient concomitantly with a drug in order to potentiate the effect of the drug by increasing acetylcholine levels in the brain or other tissues, and/or to suppress, or block the development of, unwanted side effects of the drug, by increasing acetylcholine levels in the brain or other tissues.
    Type: Grant
    Filed: March 17, 1982
    Date of Patent: January 13, 1987
    Assignee: Massachusetts Institute of Technology
    Inventors: John H. Growdon, Richard J. Wurtman
  • Patent number: 4626527
    Abstract: Choline or a natural or synthetic compound that dissociates to form choline is administered to a patient who has or is about to participate in major exercise in order to decrease fatigue by increasing acetylcholine levels in the brain or other tissues. The term "fatigue" as used herein means the subjective feeling of tiredness as well as the fatigue of muscles and the actual decrease of performance.
    Type: Grant
    Filed: September 28, 1985
    Date of Patent: December 2, 1986
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard J. Wurtman, Lydia Conlay, Krzysztof Blusztajn
  • Patent number: 4624852
    Abstract: Choline or a choline precursor is administered to a patient together with an amino acid which is a precursor to a neurotransmitter in order to give a synergistic result for the two components.
    Type: Grant
    Filed: May 21, 1984
    Date of Patent: November 25, 1986
    Assignee: Massachusetts Institute of Technology
    Inventor: Richard J. Wurtman
  • Patent number: 4609647
    Abstract: Cytidyl diphosphocholine is administered to a patient alone to increase brain acetylcholine levels or concomitantly with a drug in order to potentiate the effect of the drug by increasing acetylcholine levels in the brain or other tissues, and/or to suppress, or block the development of, unwanted side effects of the drug, by increasing acetylcholine levels in the brain or other tissues.
    Type: Grant
    Filed: October 9, 1985
    Date of Patent: September 2, 1986
    Assignee: Massachusetts Institute of Technology
    Inventors: John H. Growdon, Richard J. Wurtman
  • Patent number: 4598094
    Abstract: Tyrosine or a tyrosine precursor is administered concomitantly with an indirect-acting sympathomimetic amine drug to increase the level of norepinephrine that can be released in sympathetic neuron synapses.
    Type: Grant
    Filed: September 25, 1985
    Date of Patent: July 1, 1986
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard J. Wurtman, Timothy J. Maher
  • Patent number: 4569929
    Abstract: Cytidyl diphosphocholine is administered to a patient alone to increase brain acetylcholine levels or concomitantly with a drug in order to potentiate the effect of the drug by increasing acetylcholine levels in the brain or other tissues, and/or to suppress, or block the development of, unwanted side effects of the drug, by increasing acetylcholine levels in the brain or other tissues.
    Type: Grant
    Filed: December 22, 1983
    Date of Patent: February 11, 1986
    Assignee: Massachusetts Institute of Technology
    Inventors: John H. Growdon, Richard J. Wurtman
  • Patent number: 4542123
    Abstract: A composition comprising tyrosine and a carbohydrate is administered in amount to increase brain tyrosine levels.
    Type: Grant
    Filed: January 11, 1982
    Date of Patent: September 17, 1985
    Assignee: Massachusetts Institute of Technology
    Inventor: Richard J. Wurtman
  • Patent number: 4470987
    Abstract: The risk of ventricular fibrillation in animals is reduced by administering tyrosine, a tyrosine precursor, threonine or mixtures thereof, either alone or in combination with a substance which is known to reduce the risk of ventricular fibrillation. A novel composition is provided comprising a unit dosage form of tyrosine, a precursor for tyrosine, threonine or mixtures thereof and a substance which is known to reduce the risk of ventricular fibrillation.
    Type: Grant
    Filed: May 18, 1981
    Date of Patent: September 11, 1984
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard J. Wurtman, Bernard Lown
  • Patent number: 4456598
    Abstract: Choline or a natural or synthetic compound that dissociates to form choline is administered to a patient concomitantly with a drug in order to potentiate the effect of the drug by increasing acetylcholine levels in the brain or other tissues, and/or to suppress, or block the development of, unwanted side effects of the drug, by increasing acetylcholine levels in the brain or other tissues.
    Type: Grant
    Filed: May 3, 1982
    Date of Patent: June 26, 1984
    Assignee: Massachusetts Institute of Technology
    Inventors: John H. Growdon, Richard J. Wurtman
  • Patent number: 4452815
    Abstract: Compositions containing controlled amounts of d,l-fenfluramine are administered to block the intermittent carbohydrate cravings without necessarily suppressing other food intakes.
    Type: Grant
    Filed: July 30, 1981
    Date of Patent: June 5, 1984
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard J. Wurtman, Judith Wurtman
  • Patent number: 4435424
    Abstract: The level of a catecholamine in neuronal synapses is increased in order to improve vigor by administering a neutral amino acid composition to a human wherein an increased brain level of a catecholamine is effected when the composition contains increased amounts of tyrosine and/or phenylalanine. Increased or decreased brain levels of serotonin are obtained when the amino acid composition contains increased or decreased amounts of tryptophan.The neutral amino acid composition can be administered alone or concomitantly with a drug which increases or decreases catecholaminergic neurotransmission.
    Type: Grant
    Filed: August 31, 1981
    Date of Patent: March 6, 1984
    Assignee: Massachusetts Institute of Technology
    Inventor: Richard J. Wurtman