Patents by Inventor Richard K. Cooper

Richard K. Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5998698
    Abstract: Novel means have been discovered for increasing the resistance of an animal host (including humans) to diseases caused by intracellular bacteria, protozoa, and viruses. The infection treated may, for example, be equine infectious anemia, or infection by the human immunodeficiency virus. Novel means have also been found for treating tumors Augmentation of the host's defenses against infectious diseases or tumors is achieved by "arming" the host's cells with an exogenous gene encoding a natural or synthetic lytic peptide. For example, the transfection of hematopoietic stem cells and embryonic cells will produce animals with enhanced disease resistance; and transfection of TIL (tumor infiltrating lymphocytes) cells or other cells can be used in the treatment of tumors. Genes coding for a cecropin or other native or synthetic lytic peptide can be transferred and stably expressed in mammalian, bony fish, other vertebrate, and other animal cells.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 7, 1999
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Richard K. Cooper, Frederick M. Enright
  • Patent number: 5719055
    Abstract: A novel transposen-based vector has been developed that enhances the integration of DNA into a host genome, particularly a eukaryotic genome. The novel vector has been used, for example, in the transformation of mammalian and fish cells with a gene coding for the inductive expression of the lytic peptide cecropin B, and in the production of transgenic fish containing a gene coding for the inductive expression of the lytic peptide cecropin B. This vector shows greater transformation efficiencies than do other means for transforming a gene into a eukaryotic chromosome. The novel vector allows the rapid and efficient transformation of a eukaryotic genome. Its use does not require the high level of skill needed for microinjections. Nor does it rely on homologous recombination events for a successful transformation, as do the prior methods of microinjection, electropotation, and lipofection. A novel modification of mini-transposons was made to adapt them to carry a gene of interest into a genome.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 17, 1998
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Richard K. Cooper
  • Patent number: 5556782
    Abstract: Novel means have been discovered for increasing the resistance of a mammalian host (including humans) to diseases caused by intracellular bacteria, protozoa, and viruses. Novel means have also been found for treating tumors. Augmentation of the host's defenses against infectious diseases or tumors is achieved by "arming" the host's cells with a gene encoding the lytic peptide cecropin B. The host's own leukocytes, other cells involved in resistance to infection, or other cells are transformed, and expression of the gene is induced when needed to combat pathogens. Transfection of hematopoietic stem cells with the cecropin B gene will enhance disease resistance in mammals; and transfection of TIL (tumor infiltrating lymphocytes) cells or other cells can be used in the treatment of tumors.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: September 17, 1996
    Assignee: Board of Supervisors of Louisiana State University and Agricultural & Mechanical College
    Inventors: Richard K. Cooper, Frederick M. Enright
  • Patent number: 5536658
    Abstract: The present invention provides a chondroitinase attenuated Edwardsiella ictaluri bacteria. Further, this invention provides a vaccine comprising a protective amount of a chondroitinase attenuated strain of Edwardsiella ictduri bacteria and a method for protecting a fish from Enteric Septicemia comprising administering the vaccine to the fish.
    Type: Grant
    Filed: October 23, 1992
    Date of Patent: July 16, 1996
    Assignee: The University of Georgia Research Foundation
    Inventors: Emmett B. Shotts, Jr., Richard K Cooper, II
  • Patent number: 4442522
    Abstract: A high efficiency, free electron laser utilizing a circular relativistic electron beam accelerator and a circular whispering mode optical waveguide for guiding optical energy in a circular path in the circular relativistic electron beam accelerator such that the circular relativistic electron beam and the optical energy are spatially contiguous in a resonant condition for free electron laser operation. Both a betatron and synchrotron are disclosed for use in the present invention. A free electron laser wiggler is disposed around the circular relativistic electron beam accelerator for generating a periodic magnetic field to transform energy from the circular relativistic electron beam to optical energy.
    Type: Grant
    Filed: January 26, 1982
    Date of Patent: April 10, 1984
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Charles A. Brau, Norman A. Kurnit, Richard K. Cooper
  • Patent number: 4350955
    Abstract: Means for producing a region of homogeneous magnetic field remote from the source of the field, wherein two equal field sources are arranged axially so their fields oppose, producing a region near the plane perpendicular to the axis midway between the sources where the radial component of the field goes through a maximum. Near the maximum, the field is homogeneous over prescribed regions.
    Type: Grant
    Filed: October 10, 1980
    Date of Patent: September 21, 1982
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Jasper A. Jackson, Richard K. Cooper
  • Patent number: 3951074
    Abstract: A high-speed terrestrial vehicle that is magnetically levitated by means of magnets which are used to induce eddy currents in a continuous electrically conductive nonferromagnetic track to produce magnetic images that repel the inducing magnet to provide primary lift for the vehicle. The magnets are arranged so that adjacent ones have their fields in opposite directions and the magnets are spaced apart a distance that provides a secondary lift between each magnet and the adjacent magnet's image, the secondary lift being maximized by optimal spacing of the magnets.
    Type: Grant
    Filed: September 27, 1974
    Date of Patent: April 20, 1976
    Assignee: The United States of America as represented by the United States Energy Research and Development Administration
    Inventor: Richard K. Cooper