Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt or in-vivo hydrolysable ester thereof: ##STR1## wherein R.sup.1 is hydrogen or an amino protecting group and R is substituted methyl; optionally substituted C.sub.2-12 alkyl, alkenyl or alkynyl; carbocyclyl; aryl or heterocyclyl. These compounds have antibacterial properties, and therefore are of use in the treatment of bacterial infections in humans and animals caused by a wide range of organisms.

Abstract: A compound of the formula: ##STR1## wherein Y represents OH or a halogeno group;D represents hydrogen or a cyano group;B represents hydrogen or a methyl, ethyl or vinyl group;A represents methyl;n is 0, 1 or 2;with the proviso that(1) when the CH.sub.2 CH.dbd.CHB group is in the 4-position with respect to the CHDY group, then D must be hydrogen and B must be methyl, ethyl or vinyl and the configuration about the double bond in the CH.dbd.CHB group must be Z and(2) when the group CH.dbd.CHB is in the 3-position with respect to the CHDY group and D is CN then n must be 0 and(3) when the group CH.sub.2 CH.dbd.CHB is in the 2 or 3-position with respect to the CHDY group, then D is CN, are useful in the production of pesticidal esters of chrysanthemic and related acids.

Abstract: Pesticidal compounds have the formula: ##STR1## wherein D represents hydrogen or a cyano groupX represents chlorine or bromineA represents an alkyl groupn is 0 or an integer of 1-4 andRCOO is the residue of an acid RCOOH whose .alpha.-cyano-3-phenoxybenzyl ester has pesticidal properties. They are prepared by esterification methods.

Abstract: A compound of formula I: ##STR1## in which formula: D represents hydrogen or a cyano group;X represents halogen;A represents an alkyl group (typically a C.sub.1 -C.sub.6 alkyl group);n is 0 to 4;RCOO. represents a residue of an acid RCO.sub.2 H, which acid, or an ester-forming derivative of which acid, on reaction with .alpha.-cyano-3-phenoxybenzyl alcohol or an ester-forming derivative thereof, gives rise to an .alpha.-cyano-3-phenoxybenzyl ester having pesticidal properties.

Abstract: A compound of formula (I): ##STR1## in which R is optionally substituted phenyl; C.sub.3-8 cycloalkyl; C.sub.5-8 cycloalkenyl; C.sub.1-8 alkyl which may be straight or branched; C.sub.2-8 alkenyl which may be straight or branched; 5- or 6- membered heterocyclyl; or optionally substituted phenyl C.sub.1-4 alkyl, each of Y and Z, which may be the same or different, is oxygen or sulphur; and X is --CH.sub.2 -- or oxygen, a process for the preparation of such compounds and their use in human and veterinary medicine.

Abstract: In the preparation of 2,6-dimethylphenylisothiocyanate by reacting N-(2,6-dimethylphenyl)acetamide with sodium hydride in an organic solvent to form the corresponding anion of said amide, then reacting carbon disulfide with said anion to form said 2,6-dimethylphenylisothiocyanate, unexpectedly high yields are obtained by using as the organic solvent tetrahydrofuran or a mixture of N,N-dimethylacetamide and toluene. 2,6-Dimethylphenylisothiocyanate is an intermediate in the preparation of xylazine useful, for instance, as a sedative, an analgesic and muscle relaxant.

Abstract: Pesticidal compounds have the formula: ##STR1## wherein D represents hydrogen or a cyano or ethynyl group;B represents hydrogen or an alkyl or alkenyl group;A represents an alkyl group or a halogeno group or a CF.sub.3 group;n is 0 or an integer of 1-4; andRCOO is the residue of an acid RCOOH which is a 2,2-dimethyl-cyclopropane carboxylic acid carrying at the 3-position a dihalovinyl, an alkenyl or a carboalkoxyalkenyl group, provided that (1) when the group --CH.sub.2 CH.dbd.CHB is located at the 4-position on the ring with respect to the ester linkage, then D must be hydrogen and the group carried at the 3-position on the cyclopropane ring of the acid must be a dihalovinyl group and (2) when the group --CH.sub.2 CH.dbd.CHB is located at the 3-position on the ring and D is a CN group, then n must be 0.