Patents by Inventor Richard Li

Richard Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11905533
    Abstract: Disclosed herein is an adeno-associated virus (AAV) particle comprising a surface-bound peptide that enhances transduction of cells across the blood-brain barrier (BBB). Also disclosed herein is a modified AAV capsid protein comprising an insertion of a polypeptide that enhances transduction of cells across the BBB, and an AAV particle comprising the modified AAV capsid protein. Specific peptides are provided. Pharmaceutical formulations and method of administering/delivering a nucleic acid to a cell of the brain and/or central nervous system are also disclosed.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: February 20, 2024
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Chengwen Li, Richard Jude Samulski
  • Patent number: 11901935
    Abstract: The present application relates to wireless communications suitable for smart manufacturing and industrial automation. In particular, the application proposes a wireless communication device (UE) and a network device (BS), in particular suitable for cyclic communication. The BS is configured to provide a first information defining a hopping sequence to a UE, and to provide a second information to the UE defining when the hopping sequence should be repeated, in particular periodically repeated. The UE is accordingly configured to receive the first information from the BS, and to receive the second information from the BS. The hopping sequence specifies at least two spatial resources and/or at least two radio resources, which the UE is configured to use for transmissions to and/or from the BS.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: February 13, 2024
    Inventors: Konstantinos Manolakis, Daniel Medina, Mario Hernán Castañeda Garcia, Richard Stirling-Gallacher, Zhongfeng Li
  • Patent number: 11902817
    Abstract: A device may receive input data associated with a wireless network, and may extract data from the input data to generate extracted data. The device may create PRB images based on the extracted data, and may process the PRB images, with a first model, to associate labels with each of the PRB images. The device may process the labels and the PRB images, with a second model, to identify potential issues associated with the PRB images, and may process data identifying the potential issues associated with the PRB images, with a third model, to compress the data identifying the potential issues into an array. The device may process the array, with a fourth model, to determine probability scores associated with the potential issues, and may select a potential issue with a greatest probability score as a detected issue. The device may perform actions based on the detected issue.
    Type: Grant
    Filed: October 6, 2022
    Date of Patent: February 13, 2024
    Assignee: Verizon Patent and Licensing Inc.
    Inventors: Christian Winter, Brian A. Ward, Richard S. Delk, Xia Li
  • Publication number: 20240026168
    Abstract: Curable heat-expanding debondable coating compositions for use as a pre-coating or surface preparation in conjunction with adhesive composition. The debondable coating compositions include heat-expandable microspheres which are designed to expand in a specified temperature range, thereby debonding the coating compositions from a substrate. Adhesive compositions are overlaid on the debonding coating and are subsequently debonded from the substrate along with the debondable coating composition.
    Type: Application
    Filed: September 25, 2023
    Publication date: January 25, 2024
    Inventors: Wenhua Zhang, Richard Corrao, Ling Li
  • Patent number: 11877595
    Abstract: At least one example embodiment provides a non-combustible smoking system or kit, comprising: a cartridge having a first end and a second end; and a tobacco containing section having a third end and a fourth end. The cartridge includes: a pre-vapor formulation reservoir element and a pre-vapor heating element coupled to the pre-vapor formulation reservoir element. The tobacco containing section includes a tobacco housing and a tobacco heating element. The first end of the cartridge is configured to be connected to the fourth end of the tobacco containing section, and the second end of the cartridge is configured to be connected to the third end of the tobacco containing section.
    Type: Grant
    Filed: April 8, 2021
    Date of Patent: January 23, 2024
    Inventors: Christopher S. Tucker, Barry Smith, Ed Cadieux, David Bennett, Raquel Olegario, San Li, Georgios Karles, Richard Jupe, Peter Lipowicz, Benjamin Ragland
  • Patent number: 11880957
    Abstract: One example method involves operations for receiving a request to transform an input image into a target image. Operations further include providing the input image to a machine learning model trained to adapt images. Training the machine learning model includes accessing training data having a source domain of images and a target domain of images with a target style. Training further includes using a pre-trained generative model to generate an adapted source domain of adapted images having the target style. The adapted source domain is generated by determining a rate of change for parameters of the target style, generating weighted parameters by applying a weight to each of the parameters based on their respective rate of change, and applying the weighted parameters to the source domain. Additionally, operations include using the machine learning model to generate the target image by modifying parameters of the input image using the target style.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: January 23, 2024
    Assignee: Adobe Inc.
    Inventors: Yijun Li, Richard Zhang, Jingwan Lu, Elya Shechtman
  • Publication number: 20240015166
    Abstract: A computer-implemented method is disclosed. The method includes: authenticating a user for login to a service for a first authenticated user session; in response to authenticating the user, sending, to a client device associated with the user, a first data string associated with a first validity period; receiving, from the client device after expiry of the first authenticated user session, a data access request to access protected data, the data access request including the first data string; validating the first data string based on checking the first validity period; and in response to determining that the first data string is valid, transmitting, to the client device, a data access response including at least a subset of the requested protected data.
    Type: Application
    Filed: September 26, 2023
    Publication date: January 11, 2024
    Applicant: The Toronto-Dominion Bank
    Inventors: Denny Devasia KURUVILLA, Esli GJINI, Sarah REEVE, Matija BOSNJAKOVIC, Guy DAGMARA, Jaspal Singh SAMRA, Abhiney NATARAJAN, Haobin LI, Richard YU, Md Abdur Razzak CHOWDHURY, Dani KARTIKAY, Ryan WU, Andrey PETROV, Peter HORVATH, Prashanth DAPPULA, Sivashanthan SIVAPALAN, Nolan GLYNN-UDROW
  • Publication number: 20240010797
    Abstract: A composition contains filler particles dispersed in a matrix material, wherein the matrix material includes: (a) a first polyorganosiloxane that comprises an average of 2 or more succinic anhydride groups per molecule; and (b) a second polyorganosiloxane other than the first polyorganosiloxane; wherein the filler particles are present at a concentration in a range of 15 to 80 volume-percent based on composition volume and wherein the first polyorganosiloxane is present at a concentration sufficient to provide succinic anhydride groups at a concentration of 0.30 to 200 micromoles per gram of matrix material.
    Type: Application
    Filed: January 13, 2022
    Publication date: January 11, 2024
    Inventors: Zhanjie Li, Kyle McDonald, Andrés E. Becerra, Joseph Sootsman, Chi-Hao Chang, Darren Hansen, Dongchan Ahn, Richard Cooper
  • Patent number: 11865219
    Abstract: A concentrated liquid sanitizing and rinse composition containing peroxycarboxylic acid(s) and compatible rinse aid surfactants is disclosed. The sanitizing and rinsing compositions are formulated in a single liquid concentrate, replacing a traditional dual product of a sanitizer and rinse aid. The sanitizing and rinsing chemistries are particularly effective at neutral pHs against gram negative organisms at elevated temperatures. Methods of using the concentrated liquid sanitizing and rinse composition are also disclosed.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: January 9, 2024
    Assignee: ECOLAB USA INC.
    Inventors: Steven J. Lange, Junzhong Li, Xin Sun, Allison Brewster, Richard Staub
  • Publication number: 20240002494
    Abstract: Described are methods and compositions for clinical proven safe and effective treatment of ulcerative colitis, particularly moderately to severely active ulcerative colitis in patients who have had an inadequate response to or are intolerant of a conventional or existing therapy by intravenous and/or subcutaneous administration of an anti-IL-12/IL-23p40 antibody.
    Type: Application
    Filed: June 16, 2023
    Publication date: January 4, 2024
    Inventors: Jewel Johanns, Katherine Li, Colleen Marano, Richard Strauss, Hongyan Zhang, Christopher O'Brien, Omoniyi Adedokun, Kimberly Shields-Tuttle
  • Publication number: 20240000977
    Abstract: Methods and/or kits for aiding, preventing, treating, or ameliorating the negative effects for a patient suffering from cancer are disclosed herein. In accordance with an aspect of the invention, that includes determining a sensitivity of one or more cancer cells by administering an immunohistochemical stain configured to determine an abundance of DACH1a gene.
    Type: Application
    Filed: October 19, 2021
    Publication date: January 4, 2024
    Inventors: Richard G. Pestell, Zhiping Li, Xuanmao Jiao, Anthony Wayne Ashton
  • Patent number: 11862674
    Abstract: The present invention provides a high voltage semiconductor device comprising a combined junction terminal protection structure with a ferroelectric material and method of making the same, the device comprises: an active area formed with the high voltage semiconductor device; a combined junction terminal protection structure having a RESURF (Reduced Surface Field) structure, the RESURF structure comprising a first biasing field plate electrically connecting to the active area and a ferroelectric material layer positioned below the first biasing field plate and in contact with the first biasing field plate. The high voltage semiconductor device structure may further assist in raising breakdown voltage (BV) of the device and meanwhile effectively reduce on-resistance (Ron) of the device compared with current junction terminal protection structure, and then miniaturization of the device structure may be fulfilled more easily.
    Type: Grant
    Filed: June 18, 2021
    Date of Patent: January 2, 2024
    Assignee: SiEn (QingDao) Integrated Circuits Co., Ltd.
    Inventors: Min-Hwa Chi, Min Li, Richard Ru-Gin Chang
  • Patent number: 11857498
    Abstract: A medication component mixing system is formed of a first syringe, such as a female syringe, and a second syringe such as a male syringe, wherein the system is configured to mix a female portion and a male portion of the medication. The female syringe and the male syringe mechanically couple to one another in an end-to-end fashion for mixing of the contents of the female and male portions.
    Type: Grant
    Filed: September 19, 2022
    Date of Patent: January 2, 2024
    Assignee: Indivior UK Limited
    Inventors: Andrew Watkins, Qi Li, Richard L. Norton, Daniel Barnhill, Trant Holt
  • Patent number: 11862013
    Abstract: A system, method and server for a controlling a relation between a vehicle and traffic flow over a road segment. The system includes a telemetric device of the vehicle and a processor of the server. The telemetric device obtains telemetric data related to the road segment being traversed by the vehicle. The processor determines a property of the road segment based on the telemetric data and a road profile for the road segment, determines a disruption score indicative of a level of disruption in the traffic flow for the road segment based on the property, and outputs a notification signal when the disruption score is above a selected disruption threshold. The notification signal is usable for controlling the relation between the vehicle and the traffic flow.
    Type: Grant
    Filed: May 17, 2021
    Date of Patent: January 2, 2024
    Inventors: Donald K. Grimm, Richard Gordon, Chuan Li, Shu Chen, Fan Bai
  • Publication number: 20230414140
    Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
    Type: Application
    Filed: December 22, 2022
    Publication date: December 28, 2023
    Inventors: Ying Li, Apurv Ullas Kamath, Richard C. Yang, Mark C. Brister
  • Publication number: 20230414325
    Abstract: The present disclosure provides method, systems, and devices for adjusting an arch of teeth. An appliance includes a removable shell formed of a first material having a number of cavities formed therein, wherein the number of cavities are shaped to receive teeth of a patient, and an arch element extending from the removable shell in a lingual direction and across at least a portion of the arch width of the removable shell, wherein the arch element is designed to expand an arch of the teeth of the patient, wherein the arch element has a width specific to a stage of a treatment plan.
    Type: Application
    Filed: September 11, 2023
    Publication date: December 28, 2023
    Inventors: Ryan KIMURA, John MORTON, Richard SHAW, Chunhua LI
  • Publication number: 20230422347
    Abstract: A transmitting device and a receiving device for wireless communications are provided, particularly for vehicle-to-everything (V2X) or cooperative intelligent transport systems (C-ITS) communications. The transmitting device is configured to determine more than one transmission for transmitting a packet, and transmit the packet to a receiving device and/or a group of receiving devices using the determined transmissions. The receiving device is configured to receive a packet in more than one transmission from a transmitting device, and combine the transmissions to obtain the packet. Corresponding transmitting and receiving methods are also provided.
    Type: Application
    Filed: June 26, 2023
    Publication date: December 28, 2023
    Inventors: Zhongfeng Li, Yilin Li, Jian Luo, Richard Stirling-Gallacher
  • Publication number: 20230416323
    Abstract: Provided are various embodiments relating to feline erythropoietin (EPO) polypeptide analogs with one or more additional glycosylation sites and methods of producing and using the same to treat anemia in companion animals. Also provided are various embodiments relating to EPO polypeptides having a mutation in the second binding site, polypeptides comprising an extracellular domain of EPO receptor, and methods of using the same for treating polycythemia in mammals.
    Type: Application
    Filed: May 30, 2023
    Publication date: December 28, 2023
    Inventors: Hangjun Zhan, Lam Nguyen, Yongzhong Li, Qingyi Chu, Estela Garcia-Murillo, Victoria Leitman, Stephen Sundlof, Richard Chin, Shyr Jiann Li
  • Publication number: 20230405536
    Abstract: An inline static mixer includes an outer tube and an inner tube positioned inside the outer tube and arranged coaxially with respect to the outer tube with a space between the inner and outer tubes. The inner tube is operable to receive and convey a hydrocarbon stream and the outer tube is operable to receive and convey a diluent stream. At least one baffle extends from the inner tube toward the outer tube and through at least a portion of the space that is operable to generate a twisted diluent flow from the diluent stream. The twisted diluent flow and the hydrocarbon stream are mixed downstream of an outlet of the inner tube with the twisted diluent flow forming a boundary layer along an internal surface of the outer tube to minimize fouling from liquid or liquid droplets of the hydrocarbon stream after mixing.
    Type: Application
    Filed: June 12, 2023
    Publication date: December 21, 2023
    Inventors: Baozhong Zhao, Xueping Li, Kishan Thakurdin, Alejandro Carrillo, Richard Jibb
  • Patent number: 11845122
    Abstract: A stamping machine configured to shape a sheet material including an upper binder including first teeth, a lower binder including second teeth, and a punch. A first cylinder is positioned between a lower binder and a support surface. A second cylinder is positioned between the upper binder and the lower binder. A cushion pin is positioned at the support surface that is configured to contact and control movement of the lower binder relative to the punch. A force exerted by the second cylinder is greater than that exerted by the first cylinder, and the force exerted by the cushion pin is greater than that exerted by the second cylinder. The first and second cylinders and the cushion pin are used to control when the first and second teeth are permitted to engage the sheet material, which assists in preventing or minimizing spring back of the sheet material through post-stretching.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: December 19, 2023
    Assignee: FCA US LLC
    Inventors: Dajun Zhou, Kaiping Li, Robert D Miller, Richard J Siemen, Yongiun Zhou