Abstract: The present invention teaches multiple three-dimensional nanosensing geometries for simultaneously assaying both large and small bio-related molecules in one device. The invention delivers broader sensitivity and selectivity than devices that assay small or large molecules separately. The combination assays all classes of molecules, e.g., proteins, lipoproteins, nucleoproteins, lipids, phospholipids, carbohydrates, nucleic acids, simple sugars, hormones, volatile organic compounds, drugs, drug metabolites, etc. Broad collection enables i) rapid and accurate diagnosis, ii) likely courses of treatments, and iii) timely feedback that monitors and follows the progressions of treatment(s). In one example, a patients pattern of blood lipids, proteins—including proteins with alternate cleavage patterns, peptides—including endocrine peptides, thyroxine (and/or other hormones), and drug metabolites, forms a profile specific to that patient at that time.

Abstract: A social network server computer forms a social network including a primary member linked to a plurality of secondary members, each of whom provides a member profile. A network profile is generated based on an analysis of the member profiles. A social network server computer then determines a relative value of the social network with respect to a merchant by analyzing the associated network profile, and offers a merchant incentive to the primary member of the network as a function of the determined relative value. In a second embodiment, a merchant computer associated with a merchant determines a relative value of the social network with respect to a merchant by analyzing the network profile, and offers a merchant incentive to the primary member of the network as a function of the determined relative value. The merchant incentives may be also offered to the secondary members of the associated social network.

Abstract: The present invention provides a process and method for repurposing existing compounds by leveraging genomic, phenotypic and pharmacological data to cure disease. Applying advanced mathematical analytics using massively interconnected computing capabilities to identify target rich sets of existing compounds available for animal testing at the earliest stage in the process collapses cycle time of development, dramatically reducing costs. Target rich sets obtained through this invention produce compounds or compositions which each have a demonstrated ability to modulate disease or an associated phenotypic expression. By rendering the mechanism of action irrelevant, this invention collapses the time and cost to discovery of an efficacious drug from decades to days and from $Billions to $Millions.

Abstract: Disclosed is a device for testing or screening individuals for symptoms of disease, exposure to restricted chemical or bio-hazards. The device may be configured as a compact box or tubular assay chamber. A sluice or walkway is provided for assaying moving animals. The present device assays volatile compounds, especially volatile organic compounds (VOCs) emitting from a subject individual. Different VOCs are produced as metabolic activity changes as an individual addresses a pathogenic, chemical or biological stress or progresses through normal biologic cycles such as sleepwake, seasonal, fertility, etc. The system is especially advantageous for timing breeding events and apportioning feed for desired levels of milk production and calf health. Nanosensor elements within the device provide assessment of multiple VOCs to a system with integrated analysis capacities that rapidly compares instant data to a developed database.

Abstract: A disease, by definition, is an undesired or abnormal state. Diseases are characterized by symptoms that may change during disease progression. But each symptom is underpinned by at least one factor that alters metabolism within cells of the body. Without at least one change in cell activity (metabolism) there would be no symptoms. These metabolic alterations involve modified rates or occurrence of alternate biochemical reactions. Disease-associated patterns of reactions (metabolisms) produce a characterizing or signature pattern of reaction products and byproducts. These metabolites, especially volatile organic metabolites (VOCs), may be assayed using a device of this invention to produce results that indicate a subject's disease or class of diseases and to differentiate between diseases.

Abstract: A toddler walker having a body comprising a bottom panel, and a front panel, a rear panel, and a pair of side panels attached to the bottom panel so as to form an open box; at least four wheel assemblies, each comprising a wheel rotatably affixed to the body so that when the wheels rotate the body moves via the wheels along a surface; a handlebar assembly comprising a handlebar, means for adjusting the handlebar to a desired vertical position, and a pair of leg channels pivotally connected to the side panels to enable a toddler to grasp said handlebar assembly when located behind the body and direct movement of the body along the surface; and a display device assembly pivotally connected to the handlebar assembly and comprising means for removably attaching a display device further comprising means for adjusting the height of the display device.

Abstract: The present invention discloses a system and method for preparing and delivering various health and longevity compositions. This invention is designed to improve the quality of life and lifespan of mammals. The compositions of the present invention are selected and designed for the purpose of efficiently delivering health and longevity enhancing therapies through oral supplementation; misting; nasal spray; intravenous, IM, and/or sub-cutaneous, injection; suppository; etc. A non-toxic therapeutic anabolic hormone replenishment is combined with rapamycin and cannabidiol. The three compounds work together to improve quality of life and healthy lifespan. Preferred additional included supplements may include metformin, growth hormone, and/or supplemented minerals. A preferred embodiment features low dose continuous supplementation, e.g., to be incorporated with a daily meal. The process of the present invention delivers an orally ingested substance, e.g., a snack, a human food supplement, an animal treat, etc.

Abstract: This invention provides systems and methods for improved biosensor production resulting in enhanced surface adhesion with stronger dielectrics and reduced inter-sensor variance. The present invention greatly improves both the reliability and depth of data obtained. These greatly improved biosensors are ideally suited for the detection of early stage diseases and conditions such as cancers, pathogens, and toxic exposures. Practicing this invention allows for commercially viable manufacturing and the refurbishing of spent biosensors.

Abstract: The present invention teaches a system and method for identifying, targeting and destroying cancer cells without harming healthy tissue. This invention uses a vector engineered virus to selectively seek out cells that are both hotter than normal with a pH factor that is lower than normal thereby identifying cells that are cancerous regardless of location. Cancer succeeds for two reasons: i) rapid growth and ii) failure of the body's immune system to recognize the aberrant cells. This novel approach of using a dual vectored virus creates a dominant preference for locating and attaching to cancer cells, eliminating the need for chemotherapy, radiation therapy, and most major surgeries.

Abstract: A portable display device assembly suitable for use with a separate apparatus such as a toddler walker, cart, wagon or similar apparatus and which is adjustable to suit the needs of the user. The portable display device assembly has means for holding a display device, which includes a display device support panel and a display device support rail slidingly engaged with the display device support panel such that the height of the display device support rail may be raised or lowered with respect to the display device support panel. There is also a means for pivoting the display device support panel and means for attaching the means for holding a display device to a separate apparatus.

Abstract: Hospitals are stressful environments where injured and diseased persons receive healing or palliative care. Machine devices are used to monitor individual's health status and often deliver treatment. Treatment may be delivered with a goal of allowing the individual to live a relatively normal life outside the hospital, but treatments may be delivered with a goal of increasing an individual's comfort including reduction of hospital induced stress. Hospitals generally have specialized units, e.g., trauma, maternity, neonatal, pediatric, intensive car, surgery, medical, rehabilitation, neurologic, oncologic, etc. Many units may be sub-specialized, e.g., pediatric oncology, gynecologic surgery, orthopedic surgery, etc. Many units will have associated intensive care units where the more seriously ill individuals receive specialized care including intensive monitoring and varying degrees of pharmacologic and/or mechanical life or organ support.

Abstract: A portable display device assembly suitable for use with a separate apparatus such as a toddler walker, cart, wagon or similar apparatus and which is adjustable to suit the needs of the user. The portable display device assembly has means for holding a display device, which includes a display device support panel and a display device support rail slidingly engaged with the display device support panel such that the height of the display device support rail may be raised or lowered with respect to the display device support panel. There is also a means for pivoting the display device support panel and means for attaching the means for holding a display device to a separate apparatus.

Abstract: A toddler walker having a body comprising a bottom panel, and a front panel, a rear panel, and a pair of side panels attached to the bottom panel so as to form an open box; at least four wheel assemblies, each comprising a wheel rotatably affixed to the body so that when the wheels rotate the body moves via the wheels along a surface; a handlebar assembly comprising a handlebar, means for adjusting the handlebar to a desired vertical position, and a pair of leg channels pivotally connected to the side panels to enable a toddler to grasp said handlebar assembly when located behind the body and direct movement of the body along the surface; and a display device assembly pivotally connected to the handlebar assembly and comprising means for removably attaching a display device further comprising means for adjusting the height of the display device.

Abstract: The present invention provides a platform, system and devices for testing or screening individuals for symptoms of disease, exposure to chemicals or biohazards. The device may be configured similar to the appearance of familiar airport screening devices, but may be configured for use in a people moving device or a walkway. The present device assays volatile compounds, especially volatile organic compounds (VOCs) emitting from a subject person, group or item. Different VOCs are produced dependent on metabolic changes in response to pathogenic, chemical, or biological stresses. Nanosensor elements within the device provide assessments of multiple VOCs to the platform with its integrated analysis capacities that rapidly compare instant data to a developed database. Each chamber may participate in an interconnected system sharing data for continuous improvement of assay procedures and comparison results.

Abstract: The present invention provides a device and process that rapidly assesses volatile organic compounds (VOCs) present in a gaseous state by reading gas emitted through a subject's skin into the ambient surroundings. The device delivers rapid high-sensitivity capture, classification and pattern recognition to identify a unique VOC profile derived from that bio-sample. A flexible probe module can be appropriately configured with attachments to collect gases from the air surrounding any person, any area enclosed or proximal to a potential VOC source, and/or in clinical applications, near any skin surface, from zones or areas within or immediate adjacent to a body orifice such as nasal passage, otic canal, mouth, armpit, vagina, urethra, navel, anus, vagina, scalp, torso, palm, foot, etc. The device thus provides a practical screening device for clearing persons of interest, e.g., in a waiting room, planning to enter a room or building, a client seeking a personal meeting, etc.

Abstract: The present invention provides an improved system, device, and method for determining a comprehensive state of health in real time using non-invasive patient testing. The invention characterizes disease and other states of health by simultaneously assaying both liquid and gas in a sample or samples. During metabolism, the body performs a large variety of biochemical reactions. Reaction products, reaction by-products, and breakdown products are transported by the circulatory system throughout the body. Many of these molecular products are labile and volatilize into gases from bodily liquids. In gas form, these compounds appear as volatile organic compounds (VOCs).

Abstract: The present invention provides systems, methods, and devices for autonomous bio-powered medical management and reporting. The systems allow for interactivity between multiple devices for various activities including, but not limited to: medical diagnostics, therapeutic modulation, recording, and reporting. One or more of the autonomous bio-powered devices can be wearable and/or implantable (e.g., subdermal, spinal, cranial, pulmonary, musculoskeletal, urethral, etc. monitoring and control). These can replace, with a continuous stream of current status reports: thermometers, pulse oximeters, CO2 monitors, local circulation, local, regional or orgasmic nutrition status, cardiac rate and output, glucose, pharmaceutical levels, electrolytes, balance, individual muscles, muscle systems, sensory inputs, auditory inputs, visual inputs, etc., to arrive at a capability for delivering modulating treatments and/or induce mechanical, medical and/or physiological responses.

Abstract: The present invention provides methods and tools for improving training regimes and optimizing exercise effects. It is ideally suited for rehabilitation services, sports medicine, gym workouts, occupational therapy, physical therapy, and training setups including especially arduous endeavors or occupations, such as military personnel, fighter pilots, astronauts, law enforcement, intense athletes, etc. This invention provides enhanced biofeedback towards a complete and comprehensive understanding of the body's real-time metabolic status and capabilities. Specialists, such as cardiologists and vascular surgeons, will find the simultaneous feedback from separate quadrants of the body especially useful in predicting future events. A series of wearable wireless nanosensor appliances on the body and/or in handlebars, grips, gloves, etc., monitors biomolecules emitted from hands, ankles, fingers, head, torso, etc. The analytical system assesses real-time metabolic status of the individual.

Abstract: The present invention teaches multiple three-dimensional nanosensing geometries for simultaneously assaying both large and small bio-related molecules in one device. The invention delivers broader sensitivity and selectivity than devices that assay small or large molecules separately. The combination assays all classes of molecules, e.g., proteins, lipoproteins, nucleoproteins, lipids, phospholipids, carbohydrates, nucleic acids, simple sugars, hormones, volatile organic compounds, drugs, drug metabolites, etc. Broad collection enables i) rapid and accurate diagnosis, ii) likely courses of treatments, and iii) timely feedback that monitors and follows the progressions of treatment(s). In one example, a patient's pattern of blood lipids, proteins—including proteins with alternate cleavage patterns, peptides—including endocrine peptides, thyroxine (and/or other hormones), and drug metabolites, forms a profile specific to that patient at that time.

Abstract: Social network members control access to and utilization of their data. Static information associated with the member is acquired, and computer-based activities of the member are recorded to generate dynamic information associated with the member. A set of member preferences are acquired from the member, including an identification of a third party to whom access of the member profile is granted by the member in exchange for compensation to the member. A member profile is constructed including the static information associated with the member, the dynamic information associated with the member, and the member preferences. The member profile is transmitted to the third party identified in the member preferences, and compensation is provided to the member exchange for access to the member profile. The member profile is stored in a blockchain ledger and is updated by recording each computer-based activity to a record in the blockchain ledger.