Abstract: System and method for fluorescent light detection from biological samples to enhance the numerical aperture and/or reduce the cross-talk of the fluorescent light.

Abstract: A method for calibrating a production printing cartridge for use in an imaging system includes the steps of obtaining first standard cartridge signature color data associated with a standard printing cartridge and a first substrate, obtaining second standard cartridge signature color data associated with the standard printing cartridge and a second substrate, obtaining first production cartridge signature color data associated with the production printing cartridge and the first substrate, and estimating second production cartridge signature color data associated with the production printing cartridge and the second substrate based on the first standard cartridge signature color data, the second standard cartridge signature color data, and the first production cartridge signature color data.

Abstract: The invention relates to an optical detection system for a thermal cycling device including at least one light source, a light detection device for detecting light received from a plurality of biological samples, and a lens having a plurality of focusing lens segments greater than the plurality of biological samples to direct light into the plurality of biological samples.

Abstract: Methods and systems of processing an image. One embodiment includes applying a controlled, adaptive histogram equalization technique to improve the quality of an image. Another embodiment may include classifying an image. Both embodiments may use a concentration ratio of an image or portions thereof.

Abstract: A method of gamut mapping includes the steps of defining a mapping function establishing a continuous first derivative of change of at least one color space component from a first color gamut to a second color gamut, and applying the function to first color gamut data for the at least one color space component.

Abstract: A method for correcting color shift in an imaging system, including an imaging object, and a standard color conversion lookup table associated with the imaging object, includes measuring a plurality of test patches to obtain color data associated with the imaging object. A signature color data lookup table is generated, based on the color data, and is combined with the standard color conversion lookup table to generate a composite color conversion lookup table for use with the imaging object.

Abstract: Apparatus and method for loading a channel device for electrophoretic separation including cilia which can be deflected into wells of a multi-well tray.

Abstract: Apparatus and methods for detecting analytes in a sample are provided. The apparatus can include: one or more channels having a detection zone; one or more irradiation sources disposed for irradiating the detection zone with radiation; a detector capable of collecting at least one charge corresponding to an emission beam emitted from the detection zone, the detector having an output; and a time delay integration system coupled to the detector for effecting time delay integration of the at least one charge by accumulating the at least one charge before reading the at least one charge at the output of the detector. Various embodiments provide an apparatus with a multi-notch filter. Various embodiments provide a solid state laser, a micro-wire laser, or an organic light-emitting diode as a irradiation source.

Abstract: An apparatus for detecting analytes in a sample is provided. The apparatus can include: a flow cytometry system including one or more detection zones; one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from detectable analytes in the one or more detection zones, which have been excited by the radiation, wherein at least one detector includes an output; a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector; and a sorting mechanism, for example, to effect flow cytometry. Methods for detecting analytes in a sample are also provided.