Patents by Inventor Richard S. Smith

Richard S. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7326535
    Abstract: Epstein-Barr virus (EBV) specific polypeptides are disclosed. Also disclosed are the use of these polypeptides for the production of polypeptide-specific antibodies and the diagnosis and treatment of EBV-associated disease.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: February 5, 2008
    Assignees: Ortho Diagnostic Systems Inc., Georgetown University
    Inventors: Richard S. Smith, Gary R. Pearson, D. Elliot Parks, Susan Pothen Varghese
  • Patent number: 7235517
    Abstract: Degreasing compositions that may be used, for example, to degrease substrates such as contaminated surfaces of automobile engines are disclosed. The degreasing compositions comprise a builder, an amphoteric surfactant, and an alkoxylated acetylenic diol having the structure of formula (I) or (II): where: R1 and R4 are, independently, alkyl radicals containing from 3 to 10 carbon atoms; R2 and R3 are, independently, selected from the group consisting of methyl and ethyl; and (x+y)=2 to 50; ?where: r and t are each, independently, 1 or 2; (n+m)=1 to 30; and (p+q)=1 to 30. Certain embodiments of the degreasing composition are non-caustic, low VOC and may be low phosphate or phosphate-free.
    Type: Grant
    Filed: December 31, 2002
    Date of Patent: June 26, 2007
    Assignee: 3M Innovative Properties Company
    Inventor: Richard S. Smith
  • Patent number: 7153201
    Abstract: An oval rod sharpener having an interrupted diamond abrasive surface having plurality of holes forming wells for collecting filings during sharpening. The abrasive surface is formed by multiple layers of micron sized diamonds, such as monocrystalline diamonds. A plastic pad is provided on the tip end of the oval abrasive rod to protect a support surface on which the sharpener rests during a sharpening operation.
    Type: Grant
    Filed: July 12, 2004
    Date of Patent: December 26, 2006
    Assignee: Smith Abrasives, Inc.
    Inventor: Richard S Smith
  • Patent number: 7060283
    Abstract: Epstein-Barr virus (EBV) specific polypeptides consisting of a series of one to 1000 peptide units selected from the group consisting of peptide units ?, ?, ? and ?, wherein ? is 25 amino acids or less and has the formula (?ETFTETWNRFITHTE?) (SEQ ID NO:1), ? is 25 amino acids or less and has the formula (?GMLEASEGLDGWIHQ?) (SEQ ID NO:2), ? is 25 amino acids or less and has the formula (?HQQGGWSTLIEDNI?) (SEQ ID NO:3), ? is 25 amino acids or less and has the formula (?KQKHPKKVKQAFNPL?) (SEQ ID NO:4), ? and ? are each independently from 0 to 5 naturally occurring amino acids, and the polypeptide is capable of binding antibody in a specimen from an individual with Epstein-Barr virus (EBV)-associated disease are disclosed. Also disclosed are the use of these polypeptides for the production of polypeptide-specific antibodies and the diagnosis and treatment of EBV-associated disease.
    Type: Grant
    Filed: September 15, 1993
    Date of Patent: June 13, 2006
    Assignees: Ortho Diagnostic Systems, Inc., Georgetown Univeristy
    Inventors: Richard S. Smith, Gary R. Pearson, D. Elliot Parks, Susan Pothen Varghese
  • Publication number: 20040127380
    Abstract: Degreasing compositions that may be used, for example, to degrease substrates such as contaminated surfaces of automobile engines are disclosed.
    Type: Application
    Filed: December 31, 2002
    Publication date: July 1, 2004
    Applicant: 3M Innovative Properties Company
    Inventor: Richard S. Smith
  • Publication number: 20040013665
    Abstract: Epstein-Barr virus (EBV) specific polypeptides are disclosed. Also disclosed are the use of these polypeptides for the production of polypeptide-specific antibodies and the diagnosis and treatment of EBV-associated disease.
    Type: Application
    Filed: May 21, 2003
    Publication date: January 22, 2004
    Applicants: Ortho Diagnostic Systems, Inc., Georgetown University
    Inventors: Richard S. Smith, Gary R. Pearson, D. Elliot Parks, Susan Pothen Varghese
  • Patent number: 6506553
    Abstract: A novel assay utilizing Epstein-Barr virus (EBV) specific peptides is disclosed. The assay is particularly useful for detecting early antigen antibodies in a blood sample from an individual having an EBV-associated disease, the disease preferably being infectious mononucleosis.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: January 14, 2003
    Assignee: Ortho Diagnostics Systems, Inc.
    Inventors: Richard S. Smith, D. Elliot Parks
  • Patent number: 6215295
    Abstract: A photonic radio-frequency (RF) field probe for detecting and measuring RF fields incorporates a probe head, a fiber cable and a photodetector/power-laser unit. An antenna drives a small, fiber-coupled laser, biased by a fiber-coupled optical power converter through series resistors, together with electrical connections and supporting apparatus. Methods of calibration include use of a reference oscillator in the probe head, use of the relationship between optical power sent to the optical power converter and resulting photodetector signal, and measurement of signal-fiber attenuation from light reflected by the laser in the probe head. Other probe embodiments utilize a reflective multiple quantum well modulator and embodiments which measure all three directional components of the RF field.
    Type: Grant
    Filed: July 24, 1998
    Date of Patent: April 10, 2001
    Inventor: Richard S. Smith, III
  • Patent number: 5955413
    Abstract: Organic solvent free carpet cleaning compositions maintain the stainblocking properties of factory applied treatments. The compositions contain a methacrylic acid polymer component, a sequestering agent, an anionic surfactant, and optionally water.
    Type: Grant
    Filed: October 24, 1997
    Date of Patent: September 21, 1999
    Assignee: 3M Innovative Properties Company
    Inventors: Jason A. Campagna, Richard S. Smith
  • Patent number: 5814467
    Abstract: The present invention describes an Apo AI polypeptide capable of immunologically mimicking an Apo AI epitope. The polypeptide is useful in diagnostic methods and systems for detecting Apo AI in vascular fluid samples, and for preparation of anti-Apo AI antibodies. In addition, the polypeptide is useful in therapeutic methods for increasing esterified cholesterol in a human patient.
    Type: Grant
    Filed: August 19, 1994
    Date of Patent: September 29, 1998
    Assignee: The Scripps Research Institute
    Inventors: Linda K. Curtiss, Carole L. Banka, David J. Bonnet, Richard S. Smith
  • Patent number: 5786206
    Abstract: Methods and compositions are described for determining the level of low density lipoproteins (LDL) in plasma. Native apoprotein B-100 (apo B-100) present in LDL particles is immunologically mimicked by a polypeptide of the invention. A polypeptide includes an amino acid residue sequence corresponding to a pan epitope region of the target apoprotein. A preferred polypeptide is a fusion protein that simultaneously mimics native apo B-100 and native apo A-I. Improved assay systems and methods for determining HDL and LDL levels in a body fluid sample are also described.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: July 28, 1998
    Assignee: The Scripps Research Institute
    Inventors: Richard S. Smith, Linda K. Curtiss, Kanaka Raju Koduri, Joseph L. Witztum, Stephen G. Young
  • Patent number: 5717065
    Abstract: Antigens, immunogens, inocula, antibodies, and particularly diagnostic methods and systems relating to Epstein-Barr virus nuclear antigen (EBNA) are disclosed. The diagnostic methods and systems utilize a synthetic, random copolymer polypeptide containing about 6 to about 40 amino acid residues having a sequence corresponding to the sequence of a CMV-encoded polypeptide antigen. The diagnostic methods and systems are particularly useful in identifying infections mononucleosis during its acute phase.
    Type: Grant
    Filed: August 9, 1988
    Date of Patent: February 10, 1998
    Assignee: The Scripps Research Institute
    Inventors: Gary Rhodes, Richard S. Smith
  • Patent number: 5672651
    Abstract: This invention provides compositions for treating fibrous substrates to render those substrates durably repellent to water and oil and durably resistant to dry soil comprising a fluorochemical polymer formed by: (a) reacting a tri- or higher order isocyanate with a fluorochemical alcohol; (b) reacting the resulting product with an amount of water sufficient to react with between 5 and 50% of the isocyanate groups present in the product compound; and (c) thereafter reacting the product with a difunctional poly(oxyalkylene)-containing material.
    Type: Grant
    Filed: October 20, 1995
    Date of Patent: September 30, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: Richard S. Smith
  • Patent number: D526876
    Type: Grant
    Filed: March 14, 2005
    Date of Patent: August 22, 2006
    Assignee: Smith Abrasives, Inc.
    Inventor: Richard S. Smith
  • Patent number: D529779
    Type: Grant
    Filed: July 12, 2004
    Date of Patent: October 10, 2006
    Assignee: Smith Abrasives, Inc.
    Inventor: Richard S. Smith
  • Patent number: D486052
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: February 3, 2004
    Assignee: Smith Abrasives, Inc.
    Inventor: Richard S. Smith
  • Patent number: D493684
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: August 3, 2004
    Assignee: Smith Abrasives, Inc.
    Inventor: Richard S. Smith
  • Patent number: D498654
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: November 23, 2004
    Assignee: Smith Abrasives, Inc.
    Inventor: Richard S. Smith
  • Patent number: D499004
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: November 30, 2004
    Assignee: Smith Abrasives, Inc.
    Inventor: Richard S. Smith
  • Patent number: D499323
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: December 7, 2004
    Assignee: Smith Abrasives, Inc.
    Inventor: Richard S. Smith