Patents by Inventor Richard To

Richard To has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Methods of Treatment of HPV Related Diseases

Publication number: 20160317641

Abstract: The present invention provides methods of mucosal tissue administration of therapeutic HPV vaccines, in a prime-boost regimen, which generated antigen-specific CD8+ T cell-mediated immune responses and the expression of tissue-resident memory T cell (Trm) markers on the CD8+ T cells. In some embodiments, the inventive methods employed pNGVL4a-sig/E7(detox)/HSP70 DNA vaccine and TA-HPV in a prime-boost regimen which shows vaccination in the infected mucosal tissues, including those in the cervicovaginal tract, elicited potent antitumor effects and a more effective local immune response in the tissues and regional lymph node, when compared to intramuscular vaccination. Furthermore, targeting the induction of Trm-mediated immune responses can serve as an ideal methodology especially for therapeutic HPV vaccines.

Type: Application

Filed: August 6, 2014

Publication date: November 3, 2016

Inventors: Tzyy-Choou Wu, Chien-Fu Hung, Richard Roden
UNIFIED PROCESSING TEST STRUCTURE

Publication number: 20160321164

Abstract: A method, comprises receiving a test case on a processor, receiving an input from a user to call the test case in a first calling environment, identifying the first calling environment, setting a first indicator in a memory indicating the first calling environment, running a directive in the test case, wherein the directive calls a subroutine associated with the directive, and running the subroutine called by the directive wherein the subroutine includes receiving the first indicator indicating the first calling environment, performing a first task associated with the directive wherein the first task is performed in the first calling environment responsive to receiving the first indicator indicating the first calling environment, and outputting a result of the first task to a user on a display.

Type: Application

Filed: April 29, 2015

Publication date: November 3, 2016

Inventor: Richard L. Fine
Cord Reel Variable Current Thermal Management and Damage Detection

Publication number: 20160318412

Abstract: A battery charging assembly includes a load management system, a charging cord with a battery connector, and circuitry for detecting cord removal or damage. The load management system monitors the heat buildup in a coiled portion of the charging cord and issues a corresponding signal to control the current flowing through the cord.

Type: Application

Filed: April 28, 2016

Publication date: November 3, 2016

Inventors: John Alford, Frank Ray, Richard Unetich, Peter Veiga
FLAT PANEL LIGHTING DEVICE

Publication number: 20160320038

Abstract: The light fixture includes a frame, a substantially flat light emitting diode (LED) panel disposed within the frame, power circuitry disposed within at least one of a number of channels within the frame, and a central wire-way. The frame includes a bottom assembly and a top assembly coupled to the bottom assembly. The bottom assembly and the top assembly cooperate to form the channels within the frame. The bottom assembly has a back surface. The power circuitry is configured to electrically couple the substantially flat LED panel to an external AC power supply. The central wire-way is disposed adjacent the back surface of the bottom assembly and configured to route wiring to or from the power circuitry disposed within at least one of the channels within the frame.

Type: Application

Filed: July 13, 2016

Publication date: November 3, 2016

Inventors: J. Richard MYERS, John Araki
MATERIAL REMOVAL DEVICE AND METHOD OF USE

Publication number: 20160317181

Abstract: A catheter having a tubular body and a rotatable shaft disposed within a lumen of the tubular body. A cutting element is coupled to the rotatable shaft, the cutting element having a cutting edge, the cutting element and rotatable shaft being longitudinally moveable within the tubular body between a stored position in which the cutting element is parallel a longitudinal axis of the tubular body and a cutting position in which the cutting element is deflected between the proximal and distal ends of the tubular body to extend beyond an outer diameter of the tubular body. The cutting element is configured to cut material from the wall of a vessel at a treatment site as the catheter is pushed distally through the treatment site. The catheter includes a collection chamber positioned proximally of the cutting window.

Type: Application

Filed: April 27, 2016

Publication date: November 3, 2016

Inventor: Richard S. Kusleika
EMBOLIC DEFLECTION DEVICE

Publication number: 20160317277

Abstract: There is disclosed a porous emboli deflector for preventing cerebral emboli while maintaining cerebral blood flow during an endovascular or open surgical procedure. The device prevents the entrance of emboli of a size able to cause stroke (such as greater than 100 microns) from entering either the right or left common carotid arteries, and/or the right or left vertebral arteries by deflecting emboli downstream of these vessels. The device can be placed prior to any manipulation of the heart or aorta allowing maximal protection of the brain during the index procedure. The deflector has a low profile within the aorta which allows sheaths, catheters, or wires used in the index procedure to pass. Also disclosed are methods for insertion and removal of the deflector.

Type: Application

Filed: May 12, 2016

Publication date: November 3, 2016

Inventors: Judith T. Carpenter, Jeffrey P. Carpenter, David A. Rezac, Jeffrey C. Cerier, Richard C. Fortier, Timothy W. Robinson
HIGH POWER RELAY

Publication number: 20160322175

Abstract: A contact arrangement for a relay 1 enables a particularly high maximal current and at the same time safe operation, if it has a base 10 to which a static contact 20 is mounted and if it further comprises a movable contact 30, which is movable between a first position and a second position wherein the movable contact electrically connects the static contact 20 in its first position and wherein the movable contact is disconnected from the static contact in its second position and a stranded wire 35 connecting the second contact with a connection terminal 42 and which mechanically supports the movable contact 30.

Type: Application

Filed: July 13, 2016

Publication date: November 3, 2016

Inventors: Richard Bayer, Sven Assmus
Content Delivery

Publication number: 20160323348

Abstract: A system for delivering content at varying qualities from a server to multiple client across a network has a server side converter and a client side converter. The server side converter makes unicast requests to a server for representations of content and converts these to multiple representations to be delivered as multicast streams. The client side converter receives a request for content from clients, determines a representation of content to obtain and subscribes to an appropriate multicast stream. The client side then converts the multicast stream back into segments available to a client by unicast request. In this way, data is delivered efficiently across a network from a server side to a client side whilst maintaining compatibility that client devices can issue traditional unicast requests.

Type: Application

Filed: December 23, 2014

Publication date: November 3, 2016

Inventors: Richard BRADBURY, Andrew LIPSCOMBE
JOINTS BETWEEN A COMPOSITE SKIN AND A LOAD-BEARING COMPONENT AND METHODS OF FORMING SAME

Publication number: 20160318596

Abstract: A method of forming a direct bearing joint includes coupling a first load-bearing structure to a second load-bearing structure. The second load-bearing structure includes a first structural feature comprising a first arcuate shape. The method also includes coupling a composite skin including a second structural feature comprising a second arcuate shape to the second load-bearing structure. The composite skin is coupled to the second load-bearing structure such that the first and second structural features are mated against each other to facilitate distributing compressive loads from the second load-bearing structure into the composite skin.

Type: Application

Filed: July 13, 2016

Publication date: November 3, 2016

Inventors: Richard R. Rosman, Bernhard Dopker, Wallace Chi-Hua Chan
PLANTS AND SEEDS OF HYBRID CORN VARIETY CH089982

Publication number: 20160316692

Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH089982. The invention thus relates to the plants, seeds and tissue cultures of the variety CH089982, and to methods for producing a corn plant produced by crossing a corn plant of variety CH089982 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH089982.

Type: Application

Filed: May 1, 2015

Publication date: November 3, 2016

Inventors: Scott A. Bergemann, Fufa H. Birru, Michael Dragonuk, L. John Frederickson, Peter Guzman, Michael A. Josephs, Christopher L. Souder, Richard G. Stelpflug
Auxiliary Axle and Suspension Assembly

Publication number: 20160318567

Abstract: A vehicle suspension assembly includes providing an axle assembly having a first end including a first mounting structure and a second end, providing a first bearing block and a second bearing block, forming a first aperture in the first bearing block and a second aperture in the second bearing block, attaching the first and second bearing blocks to the first mounting structure subsequent to forming the first and second apertures; and providing a first spindle assembly coupled to the first mounting structure by a first spherical bearing located within the first aperture and a second spherical bearing located within the second aperture, wherein a first kingpin assembly extends through the first and second spherical bearings, thereby coupling the first spindle with the first mounting structure.

Type: Application

Filed: July 8, 2016

Publication date: November 3, 2016

Applicant: SAF-HOLLAND, Inc.

Inventors: Richard Conaway, Daniel R. Dykstra, Marc Johnson, Doug Thole, Boyd Freeman
UNITARY FLEXIBLE TAG ARTICLE

Publication number: 20160321960

Abstract: A unitary tag article is provided that may be characterized as a one-piece elastic sheet. The one-piece tag includes a fastener portion and a label portion that are formed from the same elastic sheet. The fastener portion is adapted to fasten onto an item, and the label portion is adapted to identify the item or provide information about the item. In one or more embodiments, the one-piece tag may serve a dual purpose of bundling items and identifying or providing information about said items.

Type: Application

Filed: May 2, 2016

Publication date: November 3, 2016

Inventors: Ginger Coleman, Peter Ferguson, Bridget Harvey, Michael Hughes, Rusty Smoke, Richard R. Spencer
GAS TURBINE ENGINE COMPRESSOR ROTOR VAPORIZATION COOLING

Publication number: 20160319667

Abstract: A gas turbine engine rotor includes a rotor that provides a cooling cavity. The cooling cavity has a first chamber and a second chamber that are fluidly connected to one another by a passageway. At least one of the first and second rotor portions is configured to support a blade that is fluidly isolated from the cavity. A phase change material is arranged in the cavity. The phase change material is configured to be arranged in the first chamber in a first state and in the second chamber in the second state. The passageway is configured to carry the phase change material between the second and first chambers once changed between the first and second states.

Type: Application

Filed: December 2, 2014

Publication date: November 3, 2016

Inventors: Mark F. Zelesky, Michael Winter, Paul E. Coderre, Richard L. Sykes
ELECTRICAL STIMULATION LEADS AND SYSTEMS HAVING A RF SHIELD ALONG AT LEAST THE LEAD AND METHODS OF MAKING AND USING

Publication number: 20160317805

Abstract: An electrical stimulation system includes a lead or lead extension; a control module coupleable to the lead or lead extension; and a continuous conductive RF shield having a first portion extending along at least a portion of the lead and a second portion configured and arranged to form a perimeter band disposed around the housing of the control module. Alternatively, an electrical stimulation lead or lead extension includes a body; first contacts disposed along the distal end portion of the body; second contacts disposed along the proximal end portion of the body; a conductive RF shield disposed over, and extending along, at least a portion of the body; and a non-conductive jacket disposed over the conductive RF shield. The non-conductive jacket defines at least one window which exposes a portion of the conductive RF shield radially beneath the at least one window.

Type: Application

Filed: April 29, 2016

Publication date: November 3, 2016

Inventors: Joshua Dale Howard, Richard Mustakos
DNA-CELL CONJUGATES

Publication number: 20160319238

Abstract: The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The modified cells can be linked to a substrate surface and used in assay or bioreactors.

Type: Application

Filed: March 1, 2016

Publication date: November 3, 2016

Inventors: Shih-Chia Hsiao, Matthew B. Francis, Carolyn Bertozzi, Richard Mathies, Ravi Chandra, Erik Douglas, Amy Twite, Nicholas Toriello, Hiroaki Onoe
Crow Bar or Pry Bar with Lever Arm and Method Therefore

Publication number: 20160318743

Abstract: Long-handled lever rotates lower cam surface about an upper pivot axle between 2 spaced-apart fixed wedge-bodies which are further held apart by a lower pivot axle. A movable wedge-body between the fixed bodies rotates on the lower axle due to a cam follower actuated by the lever cam surface. At rest without cam action, the 3 acute-angle-shaped wedge feet form a composite wedge forced into the pry space between beams, etc. With lever rotations, the movable wedge foot moves away from the fixed wedge feet by rotation about the lower pivot axle. The method mounts fixed wedges on first and second pivots. Counterclockwise movement leverages the lever about the first pivot, rotating a convex cam over a concave cam follower on an upper ankle of the movable wedge causing clockwise rotation of the movable wedge about the second pivot resulting in separation of fixed versus movable acute wedge surfaces.

Type: Application

Filed: April 26, 2016

Publication date: November 3, 2016

Inventor: Edward M. Richards
PLANTS AND SEEDS OF HYBRID CORN VARIETY CH024432

Publication number: 20160316671

Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH024432. The invention thus relates to the plants, seeds and tissue cultures of the variety CH024432, and to methods for producing a corn plant produced by crossing a corn plant of variety CH024432 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH024432.

Type: Application

Filed: April 30, 2015

Publication date: November 3, 2016

Inventors: Scott A. Bergemann, Fufa H. Birru, L. John Frederickson, Peter Guzman, Richard G. Stelpflug
Replaceable Wear Tooth Assembly

Publication number: 20160319606

Abstract: An improved tooth 21 and tooth holder 22 assembly for use with a digging implement such as a post hole digger has a first retention member 23 and a second retention member 24 each of which can be used in isolation or in combination. The first retention member 23 comprises a nylon plug having opposed serrated teeth 25 and which is pushed into an opening in the tooth holder 22. The tooth contains rigid profiles 26 and when the tooth is pushed into the tooth holder, the serrations and profiles mesh together to positively retain the tooth within the tooth holder. The second retention means 24 comprises a resilient pin. The tooth and the tooth holder have a positive and negative wedge type shape which allows the tooth to be attached in one orientation only.

Type: Application

Filed: April 11, 2016

Publication date: November 3, 2016

Inventors: Grant Richard Wright, George Anolis Boxsell
SYSTEMS AND METHODS FOR 3D POINT CLOUD PROCESSING

Publication number: 20160321820

Abstract: Generally discussed herein are systems, apparatuses, and methods for moving object detection. In one or more embodiments, a method can include computing a central value for each color of each pixel in a series of frames from a static imaging device to create a static reference frame, computing a difference between pixel values of a first frame captured after the series of frames by the static imaging device and a central value of a corresponding pixel value in the static reference frame, comparing the computed differences to a difference threshold, aggregating contiguous pixels corresponding to differences greater than the difference threshold into contiguous segments of pixels, and determining if the contiguous segments correspond to a moving object by registering the contiguous segments to pixels of a frame preceding the first frame.

Type: Application

Filed: May 1, 2015

Publication date: November 3, 2016

Inventor: Richard W. Ely
SELF-BUFFERING PROTEIN FORMULATIONS

Publication number: 20160319011

Abstract: The invention herein described, provides, among other things, self-buffering protein formulations. Particularly, the invention provides self-buffering pharmaceutical protein formulations that are suitable for veterinary and human medical use. The self-buffering protein formulations are substantially free of other buffering agents, stably maintain pH for the extended time periods involved in the distribution and storage of pharmaceutical proteins for veterinary and human medical use. The invention further provides methods for designing, making, and using the formulation. In addition to other advantages, the formulations avoid the disadvantages associated with the buffering agents conventionally used in current formulations of proteins for pharmaceutical use.

Type: Application

Filed: July 19, 2016

Publication date: November 3, 2016

Inventors: Yatin R. Gokarn, Eva Kras, Richard Louis Remmele, JR., David Brems, Susan Irene Hershenson

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