Abstract: The present disclosure is directed to systems and methods for providing a stable topological representation of pathway networks as well as features associated with these networks. The disclosure is exemplified using road networks which have applications in mapping, navigation, and autonomous vehicles. Extensions may be learned through practice of the disclosure. Utilizing implementations disclosed herein may provide advantages for data conflation between different mapping systems and map data while improving overall stability by developing a common reference standard that is tied to semantic features rather than abstract geographic representations.

Abstract: Transit Cleaning Unit is able to clean the walls, overhead, insulators third rail covers and flooring of the subway systems in a minimum amount of time. It provides an effective means of providing a clean environment for the benefit of the customers.

Abstract: A dual output laser diode may include first and second end facets and an active section. The first and second end facets have low reflectivity. The active section is positioned between the first end facet and the second end facet. The active section is configured to generate light that propagates toward each of the first and second end facets. The first end facet is configured to transmit a majority of the light that reaches the first end facet through the first end facet. The second end facet is configured to transmit a majority of the light that reaches the second end facet through the second end facet.

Abstract: An information handling system housing vents air at a grid of openings formed in a wall with a member extending outward from each intersection of the grid to define air channels. Each member terminates with a polished planar surface that reflects light against a flat underlying material. Variable angles of the polished planar surface relative to the plane of the wall creates a presentation of isolated reflections against the flat background that vary based upon a viewing angle of the housing wall.

Abstract: A seatbelt pretensioning retractor assembly for use in a vehicle is provided. The seatbelt pretensioning retractor assembly includes a housing adapted for being mounted to a frame and having an interior cavity, a pretensioner tube having an arcuate and curved shape, a sprocket rotatably mounted to the housing and fixedly coupled to a spindle, a driving element as a pretensioner rod disposed within the tube and a guide plate having a guide portion and a rod guide. The pretensioner rod extends in a longitudinal direction from a proximal end portion to a distal end portion. In addition, the pretensioner rod forms a recessed portion or a recessed section to facilitate engaging with the sprocket during pretensioning.

Abstract: Playlists comprising media objects can be modified by adding personalized supplemental media objects that can provide a customized entertainment experience. As an example, an application can overlay a playlist on a consumer's device and can call a user-configurable rules engine that can select a supplemental media object (e.g., a pre-recorded and/or dynamically synthesized media file) that is to be played with the media objects. In one example, the supplemental media object can be associated with a user-selected voice personality and can be streamed from a network storage device via a communication network coupled to the consumer device.

Abstract: The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).

Abstract: Provided are shear-thinning ocular hydrogel compositions that comprise 0.1 to 5.0 wt. % (e.g. 0.1 to 3.5 wt. % or 0.1 to 2.5 wt. %) of a microgel particle-forming polymer; and 0.5 to 100 mM of a monovalent and/or polyvalent metal ion salt as a cross-linking agent; dispersed in an aqueous vehicle. The hydrogel compositions have a pH within the range of 3 to 8 and the viscosity of the gel composition reduces when the gel is exposed to shear. The compositions comprise decorin. The may also comprise an antibiotic, such as gentamicin, and an anti-inflammatory steroid, such as prednisolone. The compositions are suitable for medical use in the treatment of the eye. For example, the compositions are suitable for use in the inhibition of scarring and/or the prevention or treatment of microbial keratitis.

Abstract: A vertical joint system for substrates is formed with joints and which engaged by relative motion in a direction perpendicular to major surfaces and of the substrate. The joints are configured to enable relative rotation of up to 3 degrees while maintaining engagement of the joints. The joints and are further configured to form two locking planes one on each of the inner and outer most sides of the joint. Engagement about the locking planes is provided by transverse outward extending surfaces. At least one surface in each pair of engaging surfaces is smoothly curved. The joints and can be further arranged to provide a third locking plane parallel to and between the locking planes. The joints are disengaged by combination of a downward rotation of one joint relative the other then application of a downward force.

Abstract: Transit Cleaning Unit is able to clean the walls, overhead, insulators third rail covers and flooring of the subway systems in a minimum amount of time. It provides an effective means of providing a clean environment for the benefit of the customers.

Abstract: The invention relates to a compound of general formula (I): wherein R1, R2, R3, R4, Q, m and n are as defined herein. The compounds are inhibitors of Bcl3 and are useful for the treatment of cancer, particularly metastatic cancer.

Abstract: A fabrication carrier for fiber optic connectors defines a body configured to removably hold a plurality of fiber optic ferrules. The body allows each of the fiber optic ferrules to be movable along its axis under a bias when the ferrules are mounted to the body. The body can be coupled to a polishing plate for use with a ferrule polishing apparatus in a polishing step. Coupling of the body to the polishing plate allows each of the ferrules to at least partially protrude past a bottom face of the polishing plate for contact with the polishing apparatus. The body of the fabrication carrier is configured as a fixture that can be used in at least one additional fabrication step aside from the polishing step when not mounted to the polishing plate.

Abstract: The invention provides a fluid pump apparatus comprising a fluid inlet, a fluid outlet, a screw member and a rotatable pump member. The screw member has at least one helical screw blade configured to be rotated by a fluid flow stream and the rotatable pump member is in fluid communication with the fluid inlet and/or fluid outlet.

Abstract: Examples described herein include multiple control systems for medical devices, such as medical ventilators. Examples of multiple control of a medical ventilator in an isolation room are described.

Abstract: The invention provides a cell binding composition comprising a shear thinning gel wherein the shear thinning gel having attached to it one or more cell selective binding agents, or the shear thinning gel having dispersed therein a plurality of gel beads, the gel beads having attached to them one or more cell selective binding agents. Methods of enriching cells using the compositions and using the cells to treat injury or disease are also provided.

Abstract: According to the present techniques there is provided a data processing device, for applying to packaging, the device having a flexible substrate, the flexible substrate comprising: storage circuitry to store device data therein; processing circuitry to process the device data; and communication circuitry to communicate with a remote resource to transmit the device data thereto; sensor circuitry to generate sensed device data, and wherein the device is configured to store the sensed device data in the storage circuitry, process the sensed device data and/or transmit the sensed device data to a remote resource.

Abstract: The present invention provides rapid-acting insulin and insulin analogue formulations. The invention further provides delivery devices, particularly infusion sets, which allow for the rapid absorption of insulin and insulin analogues, as well as other active agents. Methods of using the insulin and insulin analogue formulations as well as the insulin delivery devices for treating subjects with diabetes mellitus are also provided.

Abstract: This application is directed to performing a plurality of activities each of which is performed in a respective application with content associated with a content type selected from a group consisting of television programming, online content, on-device application, information views, and other content types. Each activity is associated with a timestamp, and described using a predefined format covering an action and content associated with the action. Each of the plurality of activities is then logged into an activities log in accordance with the predefined format. A plurality of user selectable affordances are displayed concurrently in a home screen on a display of the client device. Each of the affordances is associated with one of the plurality of activities performed with associated content, and the plurality of affordances includes at least two affordances associated with two distinct activities of the plurality of activities performed by two distinct applications.

Abstract: The invention relates to a compound of general formula (I): wherein R1, R2, R3, R4, Q, m and n are as defined herein. The compounds are inhibitors of Bcl-3 and are useful for the treatment of cancer, particularly metastatic cancer.