Abstract: A tactile stimulus presentation device includes a stage, a contact member, a drive mechanism, an information setting part, and a control part. The stage includes an opening and an arrangement surface, the arrangement surface on which a body part of a subject is arranged thereon so as to close the opening. The contact member is for giving a tactile stimulus to the subject by being in contact with the body part of the subject arranged on the arrangement surface of the stage through the opening. The drive mechanism is a mechanism for holding the contact member and moving the contact member in a direction substantially parallel to the arrangement surface and in a direction substantially perpendicular to the arrangement surface. The information setting part is configured to set information to be presented by gibing tactile stimulation to the subject by tactile stimulation.

Abstract: The brain function measurement apparatus comprises a plurality of measurement probes; a holder which is fitted to the head of a subject and comprises a plurality of probe attachment parts; a light blocking member which is arranged so as to cover the holder and blocks light from entering the plurality of probes; and a contact prevention member which prevents the light blocking member from contacting the measurement probes.

Abstract: A tactile stimulus presentation device includes a stage, a contact member, a drive mechanism, an information setting part, and a control part. The stage includes an opening and an arrangement surface, the arrangement surface on which a body part of a subject is arranged thereon so as to close the opening. The contact member is for giving a tactile stimulus to the subject by being in contact with the body part of the subject arranged on the arrangement surface of the stage through the opening. The drive mechanism is a mechanism for holding the contact member and moving the contact member in a direction substantially parallel to the arrangement surface and in a direction substantially perpendicular to the arrangement surface. The information setting part is configured to set information to be presented by gibing tactile stimulation to the subject by tactile stimulation.

Abstract: An electrophoresis plate has a plurality of separation channels provided inside a substrate. The separation channels are arranged along the surface of the substrate without intersecting each other, and the separation channels have openings on both ends on the substrate surface. When a voltage is applied between the two ends of the channel, a sample is separated by electrophoresis along the channel. The openings on one end are placed in a matrix pattern as sample inlet ports, and the pitch of that placement is set equal to the pitch of the wells of a sample plate containing the samples to be injected into the sample inlet ports. Since the pitch of the sample inlet ports pattern is equal to the pitch of the sample plate wells, sample injection can be performed quickly and conveniently even with a large number of separation channels.

Abstract: For automating the operation of an electrophoresis apparatus and improving the throughput, the present electrophoresis apparatus has two platens capable of controlling temperature of electrophoresis plates placed thereon, a loading medium charging unit for sending a loading medium under pressure, a loading medium charging nozzle mechanism having a pair of nozzles connected to the loading medium charging unit, a pipetter mechanism for dispensing samples to sample dispensing openings of the electrophoresis plates placed on the platens, a stacker mechanism for storing sample plates, a loading buffer solution supplying mechanism, a loading buffer solution dispensing mechanism connected to the loading buffer solution supplying mechanism, a power unit for allowing electrophoresis separation for each electrophoresis plate placed on the platens, and a detector for optically detecting components migrating through each electrophoresis flow channel of the electrophoresis plates.

Abstract: Capillary columns (102) pass through and are inserted in a rubber plate (14), held and fixed by elastic force of rubber, and two-dimensionally arranged on a sample injection side. it fixes the capillary columns (102) arranged on a plane in close contact by holding the same with a holder plate (6a) from below and with a rubber plate (16) from above on a detection side. In order to press the capillary columns (102) against the holder plate 6a and fix the same with the rubber plate (16), a holder plate (6b) fixing the rubber plate (16) to the holder plate (6a) on both sides of the arrangement of the capillary columns (102) is provided.

Abstract: For automating the operation of an electrophoresis apparatus and improving the throughput, the present electrophoresis apparatus has two platens capable of controlling temperature of electrophoresis plates placed thereon, a loading medium charging unit for sending a loading medium under pressure, a loading medium charging nozzle mechanism having a pair of nozzles connected to the loading medium charging unit, a pipetter mechanism for dispensing samples to sample dispensing openings of the electrophoresis plates placed on the platens, a stacker mechanism for storing sample plates, a loading buffer solution supplying mechanism, a loading buffer solution dispensing mechanism connected to the loading buffer solution supplying mechanism, a power unit for allowing electrophoresis separation for each electrophoresis plate placed on the platens, and a detector for optically detecting components migrating through each electrophoresis flow channel of the electrophoresis plates.

Abstract: An electrophoretic member is structured such that a plate member as a base plate is provided with a separating flow path in a shape of a groove, and another plate member is provided with through-holes as small reservoirs at positions corresponding to both ends of the flow path. Both plate members are bonded together, so that the flow path is disposed inside thereof and both ends of the flow path communicate with the reservoirs to constitute an integrated base plate. Larger reservoirs having a size greater than that of the small reservoirs are connected at the positions of the small reservoirs on the plate member. Thus, a sample injection quantity can be minimized.

Abstract: An electrophoresis plate has a plurality of separation channels provided inside a substrate. The separation channels are arranged along the surface of the substrate without intersecting each other, and the separation channels have openings on both ends on the substrate surface. When a voltage is applied between the two ends of the channel, a sample is separated by electrophoresis along the channel. The openings on one end are placed in a matrix pattern as sample inlet ports, and the pitch of that placement is set equal to the pitch of the wells of a sample plate containing the samples to be injected into the sample inlet ports. Since the pitch of the sample inlet ports pattern is equal to the pitch of the sample plate wells, sample injection can be performed quickly and conveniently even with a large number of separation channels.

Abstract: Capillary columns (102) pass through and are inserted in a rubber plate (14), held and fixed by elastic force of rubber, and two-dimensionally arranged on a sample injection side. it fixes the capillary columns (102) arranged on a plane in close contact by holding the same with a holder plate (6a) from below and with a rubber plate (16) from above on a detection side. In order to press the capillary columns (102) against the holder plate 6a and fix the same with the rubber plate (16), a holder plate (6b) fixing the rubber plate (16) to the holder plate (6a) on both sides of the arrangement of the capillary columns (102) is provided.

Abstract: An electrophoretic apparatus which can analyze multiple tests specimens and being comprised of an electrophoretic member having a relatively simple configuration of passages, such that one or a plurality of passages are formed inside a plate-shaped member therein in which holes are formed connecting to the passages at positions corresponding to the ends of each passage, a voltage application part for applying a voltage across the passages, a detector part for detecting a specimen within the passage and an electrophoretic-member holding part for holding a plurality of the electrophoretic members so as to provide for simultaneous electrophoretic operations.

Abstract: Capillary columns (102) pass through and are inserted in a rubber plate (14), held and fixed by elastic force of rubber, and two-dimensionally arranged on a sample injection side. It fixes the capillary columns (102) arranged on a plane in close contact by holding the same with a holder plate (6a) from below and with a rubber plate (16) from above on a detection side. In order to press the capillary columns (102) against the holder plate 6a and fix the same with the rubber plate (16), a holder plate (6b) fixing the rubber plate (16) to the holder plate (6a) on both sides of the arrangement of the capillary columns (102) is provided.

Abstract: A capillary 1 is moved to a position above a vessel 17 having a solution 15 stored therein. Then, the vessel 17 is raised while the inside of a tube 5 is opened to an ambient pressure until one end 1a of the capillary 1 is dipped into the solution 15. The solution 15 is introduced into the capillary 1 by means of capillarity. Next, the vessel 17 is lowered, to thereby removing the end 1a of the capillary 1 from the solution 15 stored in the vessel 17. Subsequently, the capillary 1 is moved to a position above a vessel 19 to which the solution 15 is to be transferred. Then, the tube 5 is connected to a pressure mechanism, thereby pressurizing the inside of the capillary 1 from another end 1b thereof. The solution 15 in the capillary 1 is then discharged to the vessel 19.

Abstract: A micro array chip is formed by high-speed in jection molding. A chip body has a thickness of 1 mm and each well has a capacity of 1.2 &mgr;L with the bottom having a wall thickness of 250 &mgr;m. An opening of each well is surrounded by an annular protrusion part, which is raised from a surface of the chip body by a height of 200 &mgr;m. The openings of wells may be closed with a sheet of sealant made of aluminum or a resin. An overall shape of the micro array chip is rectangular and is a flat plate with a level bottom surface. Therefore, the micro array chip can be used with a heat block in flat plate form, which is independent of chip specifications such as a number of wells and their shape.

Abstract: Capillary columns (102) pass through and are inserted in a rubber plate (14), held and fixed by elastic force of rubber, and two-dimensionally arranged on a sample injection side. It fixes the capillary columns (102) arranged on a plane in close contact by holding the same with a holder plate (6a) from below and with a rubber plate (16) from above on a detection side. In order to press the capillary columns (102) against the holder plate 6a and fix the same with the rubber plate (16), a holder plate (6b) fixing the rubber plate (16) to the holder plate (6a) on both sides of the arrangement of the capillary columns (102) is provided.

Abstract: A reservoir member is made of an elastic resin material. Additional reservoirs formed of through-holes are provided to the reservoir member at positions corresponding to reservoirs of an electrophoretic member. The surface of the reservoir member to be tightly attached to the electrophoretic member is formed flat. The reservoir member is tightly attached to the electrophoretic member without using any adhesive in such a way that the reservoirs align with the additional reservoirs. Thus, the capacities of the respective reservoirs can be increased. Since the electrophoretic member can be easily separated from the reservoir member, the reservoirs and additional reservoirs can be cleaned easily after the analysis, thereby reducing cross-contamination in samples.

Abstract: Capillary columns (102) pass through and are inserted in a rubber plate (14), held and fixed by elastic force of rubber, and two-dimensionally arranged on a sample injection side. It fixes the capillary columns (102) arranged on a plane in close contact by holding the same with a holder plate (6a) from below and with a rubber plate (16) from above on a detection side. In order to press the capillary columns (102) against the holder plate 6a and fix the same with the rubber plate (16), a holder plate (6b) fixing the rubber plate (16) to the holder plate (6a) on both sides of the arrangement of the capillary columns (102) is provided.

Abstract: A micro array chip is formed by high-speed injection molding. A chip body has a thickness of 1 mm and each well has a capacity of 1.2 &mgr;L with the bottom having a wall thickness of 250 &mgr;m. An opening of each well is surrounded by an annular protrusion part, which is raised from a surface of the chip body by a height of 200 &mgr;m. The openings of wells may be closed with a sheet of sealant made of aluminum or a resin. An overall shape of the micro array chip is rectangular and is a flat plate with a level bottom surface. Therefore, the micro array chip can be used with a heat block in flat plate form, which is independent of chip specifications such as a number of wells and their shape.

Abstract: An end of a capillary storing a sample in its interior is inserted into a sample reservoir in a microchip and positioned near an inlet of a channel connecting to the sample reservoir. Electrodes are placed in the other end of the capillary and a waste reservoir. A predetermined voltage is applied between the electrodes so that a potential is applied between the other end of capillary and waste reservoir. As a result, the sample in the capillary is introduced electrophoretically into a separating medium in the channel. When the sample has been introduced into the channel after the lapse of a specified time, the voltage application between the electrodes is stopped and the capillary is pulled out of the sample reservoir. The sample can be introduced into the channel without placing it in the sample reservoir in a filling amount.

Abstract: A capillary 1 is moved to a position above a vessel 17 having a solution 15 stored therein. Then, the vessel 17 is raised while the inside of a tube 5 is opened to an ambient pressure until one end 1a of the capillary 1 is dipped into the solution 15. The solution 15 is introduced into the capillary 1 by means of capillarity. Next, the vessel 17 is lowered, to thereby removing the end 1a of the capillary 1 from the solution 15 stored in the vessel 17. Subsequently, the capillary 1 is moved to a position above a vessel 19 to which the solution 15 is to be transferred. Then, the tube 5 is connected to a pressure mechanism, thereby pressurizing the inside of the capillary 1 from another end 1b thereof. The solution 15 in the capillary 1 is then discharged to the vessel 19.