Abstract: A method includes obtaining a data, applying an erasure coding procedure to the data to obtain a plurality of data chunks and at least one parity chunk, deduplicating the plurality of data chunks to obtain a plurality of deduplicated data chunks, and storing, across a plurality of nodes, the plurality of deduplicated data chunks and the at least one parity chunk.

Abstract: In general, the invention relates to a method for managing data. The method includes detecting a persistent storage device failure in a persistent storage device of a plurality of persistent storage devices, and in response to the detecting, initiating a rebuilding of data in a spare persistent storage device using checkpoint metadata and slice metadata, wherein the data is a copy of data that was stored in the persistent storage device and wherein the spare persistent storage device is not one of the plurality of persistent storage device.

Abstract: A networked system may include an HCI component expansion/replacement system that is coupled to an HCI system and that periodically updates an HCI system solution database to identify a validated components for an HCI system platform that includes the HCI system, and validated software for each of the validated components. When the HCI component expansion/replacement system receives a request for a new component type to be provided in the HCI system, existing component information about a plurality of existing components that are included in the HCI system is retrieved and used to identify a first validated component that is identified in the HCI system solution database for the HCI system platform that includes the HCI system. The HCI component expansion/replacement system then provides the first validated software that is identified in the HCI system solution database for the first validated component to the HCI system.

Abstract: A magnetic microparticle drug carrier comprising mesoporous iron oxide is described. The drug carrier has an average diameter in a range of 0.5-1.2 ?m, a BET surface area ranging from 50-300 m2/g, and a pore volume ranging from 0.15-0.65 cm3/g. The drug carrier is made using a hard mesoporous silica template which is completely removed from the deposited iron oxide. The drug carrier may be loaded with high amounts of hydrophilic anticancer chemotherapeutic drugs and/or hydrophobic hormonal anticancer drugs, and released in a pH-controlled manner inside cancerous cells. Compared to free drugs, the drug microparticle carrier displays enhanced drug accumulation inside tumor tissues, deeply penetrates into a tumor region and kills the tumor cells inside. The designed carriers described here entrap and release different kinds of anticancer drugs in a controlled manner for synergistic combinatorial chemo/hormonal cancer therapy.

Abstract: A method and system for workload aware storage replication. Specifically, the disclosed method and system entail establishing preferential transports for critical workload data targeted for replication from one cluster infrastructure to another. Existing replication solutions fail to prioritize the replication of critical over non-critical workload data, which the disclosed method and system rectify.

Abstract: A method for securing data in a data cluster is performed by a data manager of a data cluster. The method includes receiving, by a data cluster, a write request for a user to write data to the data cluster, wherein the write request comprises an object identifier (OID) associated with data and a user identifier (UID) associated with the user; sending, to a key manager, an intermediate key request, wherein the intermediate key request comprises the UID; receiving, by the data cluster from the key manager, an intermediate key; processing the data to obtain a plurality of chunks and metadata associated with the plurality of chunks; generating an encryption key using the intermediate key and the OID; encrypting the metadata using the encryption key to generate encrypted metadata; deleting, after generating the encrypted metadata, the encryption key; and storing the encrypted metadata and the plurality of chunks in the data cluster.

Abstract: In general, the invention relates to a method for processing data. The method includes receiving a write request from a host, and in response to the write request, obtaining system metadata for a system, selecting, based on the system metadata, a selected component of the system to perform a data processing operation, and initiating the data processing operation on the selected component.

Abstract: A data storage system includes a first region, a second region, and a global enumerator. The first region stores a first copy of data. The second region stores a second copy of the data. The global enumerator performs a data control analysis of the data to identify that the first region is a high regulation region and the second region is a low regulation region; in response to making the identification: updates first metadata associated with the first copy of the data to regulate access to the first copy of the data; and updates second metadata associated with the second copy of the data to deregulate access to the second copy of the data.

Abstract: Compounds, methods of synthesis, and methods of cancer treatment by arylidene-1,3-dioxane-4,6-diones. A Meldrum's acid-based chemistry and hybrid solid-liquid method. The method includes protection of ketone and aldehyde components and simultaneous immobilization on the solid phase, introduction of substituents, grafts and derivatives compatible with the protection, detachment and restoration of active carbonyl reactivity, reaction of ketone library with malonate, reacting of the products with the aldehyde library in liquid phase and separation of the products by preparative HPLC.

Abstract: A method and system for collaborative workload placement and optimization. Specifically, the disclosed method and system entail implementing metric exchange between hosts in a clustered or non-clustered environment to perform infrastructure workload placement and optimization decisions. The exchange of metrics may be performed through a lightweight service, which would not impact any existing environment resource utilization. Further, resource utilization maps may be used to offer near real-time tracking of resource utilization across the aforementioned hosts, thereby facilitating resource utilization forecasting for the efficient placement and optimization of workloads throughout the environment.

Abstract: A method and system for workload aware storage replication. Specifically, the disclosed method and system entail establishing preferential transports for critical workload data targeted for replication from one cluster infrastructure to another. Existing replication solutions fail to prioritize the replication of critical over non-critical workload data, which the disclosed method and system rectify.

Abstract: A method and system for proximity based workload and data placement. Specifically, the disclosed method and system improve the efficiency and responsiveness of workload and/or workload data access to end-users through dynamic and automated needs detection and replication or migration orchestration between infrastructures (or geographical areas).

Abstract: A method and system for dynamic auto-generation of up-to-date deployment and operations guidance for solutions. Specifically, the method and system disclosed herein entail providing guidance tailored to a combination of components and/or subcomponents constituting a specific solution infrastructure. Further, the guidance accounts for deployment and operations cycle (DOC) stages, as well as configuration dependencies, when sequencing configuration steps relevant to the specific solution infrastructure.

Abstract: A method of making a structural lightweight and thermal insulating concrete is described. The concrete has a coarse aggregate partly replaced by recycled plastic pieces. This enables the concrete to maintain a high compressive strength, low thermal conductivity, and low weight, while providing a use for waste plastic. The waste plastic pieces may comprise polyethylene in the form of flakes, fibers, or granules. Due to its low unit weight, adequate compressive strength and high thermal resistance the developed concrete can be used as a structural lightweight and thermal insulating concrete. The use of this concrete leads to economic and environmental benefits.

Abstract: In general, the invention relates to a method for managing data. The method includes detecting a failure of a persistent storage device of a plurality of persistent storage devices, and in response to the detecting, initiating a rebuilding of data in a spare persistent storage device using proactive copy metadata, checkpoint metadata, and slice metadata, wherein the data is a copy of data that was stored in the persistent storage device.

Abstract: A method for managing data includes obtaining a workload generation request, wherein the workload generation request specifies a security compliant rule, in response to the workload generation request: selecting a first set of resource devices using a resource allocation master list, initiating a security compliance test on the first set of resource devices to obtain a security compliance result, making a first determination, based on the security compliance result, that the first set of resource devices meet a security compliance criterion, and in response to the first determination: storing a virtual certificate in a security compliance database based on the security compliance result, and allocating the first set of resource devices to a workload based on the workload generation request.

Abstract: A method for managing data includes selecting a first workload, wherein the first workload is implemented on at least a resource device, obtaining a snapshot of performance metrics for the resource device, storing the snapshot of performance metrics in a performance database, making a first determination that a minimum number of previous snapshots have been obtained after a previous performance analysis, and in response to the first determination: performing a performance analysis on a set of previous snapshots of the first workload to obtain a performance report, making a second determination, based on the performance report, that the resource device does not meet standard performance, and in response to the second determination, performing a resource device remediation on the resource device.

Abstract: In general, the invention relates to a method for managing data. The method includes detecting a failure of a persistent storage device of a plurality of persistent storage devices, and in response to the detecting, initiating a rebuilding of data in a spare persistent storage device using proactive copy metadata, checkpoint metadata, and slice metadata, wherein the data is a copy of data that was stored in the persistent storage device.

Abstract: A method for managing data includes obtaining a workload generation request, wherein the workload generation request specifies a security compliant rule, in response to the workload generation request: selecting a first set of resource devices using a resource allocation master list, initiating a security compliance test on the first set of resource devices to obtain a security compliance result, making a first determination, based on the security compliance result, that the first set of resource devices meet a security compliance criterion, and in response to the first determination: storing a virtual certificate in a security compliance database based on the security compliance result, and allocating the first set of resource devices to a workload based on the workload generation request.

Abstract: In general, the invention relates to a method for managing data. The method includes detecting a persistent storage device failure in a persistent storage device of a plurality of persistent storage devices, and in response to the detecting, initiating a rebuilding of data in a spare persistent storage device using checkpoint metadata and slice metadata, wherein the data is a copy of data that was stored in the persistent storage device and wherein the spare persistent storage device is not one of the plurality of persistent storage device.