Patents by Inventor Rob Burke

Rob Burke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of treating muscle dystrophy
    Patent number: 12648999
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).
    Type: Grant
    Filed: July 8, 2025
    Date of Patent: June 9, 2026
    Assignee: Avidity Biosciences, Inc.
    Inventors: Venkata Ramana Doppalapudi, Michael David Hood, Rob Burke, Michael Caramian Cochran, Beatrice Diana Darimont, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING
    Publication number: 20260060996
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Application
    Filed: August 27, 2025
    Publication date: March 5, 2026
    Inventors: Arthur A. LEVIN, Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, Hanhua HUANG, Rob BURKE
  • Compositions and methods of treating facioscapulohumeral muscular dystrophy
    Patent number: 12529056
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
    Type: Grant
    Filed: May 9, 2024
    Date of Patent: January 20, 2026
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Barbora Malecova, Rob Burke, David Sala Cano, Beatrice Diana Darimont
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE DYSTROPHY
    Publication number: 20260014266
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).
    Type: Application
    Filed: July 8, 2025
    Publication date: January 15, 2026
    Inventors: Venkata Ramana DOPPALAPUDI, Michael David HOOD, Rob BURKE, Michael Caramian COCHRAN, Beatrice Diana DARIMONT, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY
    Publication number: 20260007766
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Application
    Filed: September 17, 2025
    Publication date: January 8, 2026
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE DYSTROPHY
    Publication number: 20250381285
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).
    Type: Application
    Filed: July 8, 2025
    Publication date: December 18, 2025
    Inventors: Venkata Ramana DOPPALAPUDI, Michael David HOOD, Rob BURKE, Michael Caramian COCHRAN, Beatrice Diana DARIMONT, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING
    Publication number: 20250381286
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Application
    Filed: August 27, 2025
    Publication date: December 18, 2025
    Inventors: Arthur A. LEVIN, Andrew John GEALL, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Michael Caramian COCHRAN, Hanhua HUANG, Venkata Ramana DOPPALAPUDI, Rachel JOHNS
  • Compositions and methods of treating facioscapulohumeral muscular dystrophy
    Patent number: 12486328
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating facioscapulohumeral muscular dystrophy (FSHD).
    Type: Grant
    Filed: July 11, 2025
    Date of Patent: December 2, 2025
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Barbora Malecova, Rob Burke, Beatrice Diana Darimont, David Sala Cano
  • COMPOSITIONS AND METHODS OF TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY
    Publication number: 20250340880
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
    Type: Application
    Filed: July 11, 2025
    Publication date: November 6, 2025
    Inventors: Barbora MALECOVA, Rob BURKE, David SALA CANO, Beatrice Diana DARIMONT
  • COMPOSITIONS AND METHODS OF TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY
    Publication number: 20250333529
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating facioscapulohumeral muscular dystrophy (FSHD).
    Type: Application
    Filed: July 11, 2025
    Publication date: October 30, 2025
    Inventors: Barbora MALECOVA, Rob BURKE, Beatrice Diana DARIMONT, David SALA CANO
  • Compositions and methods of treating muscle dystrophy
    Patent number: 12427202
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).
    Type: Grant
    Filed: May 31, 2023
    Date of Patent: September 30, 2025
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Venkata Ramana Doppalapudi, Michael David Hood, Rob Burke, Michael Caramian Cochran, Beatrice Diana Darimont, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
    Publication number: 20250296946
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Application
    Filed: June 5, 2025
    Publication date: September 25, 2025
    Inventors: Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, David Sai-Ho CHU, Joel Daniel ARIAS, Rob BURKE
  • Nucleic acid-polypeptide compositions and uses thereof
    Patent number: 12364769
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: July 22, 2025
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Andrew John Geall, Venkata Ramana Doppalapudi, Joel Daniel Arias, David Sai-Ho Chu, Michael Caramian Cochran, Rob Burke, Philip Kovach, Barbora Malecova
  • Nucleic acid-polypeptide compositions and uses thereof
    Patent number: 12365704
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Grant
    Filed: December 19, 2022
    Date of Patent: July 22, 2025
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Venkata Ramana Doppalapudi, Michael Caramian Cochran, David Sai-Ho Chu, Joel Daniel Arias, Rob Burke
  • Nucleic acid-polypeptide compositions and uses thereof
    Patent number: 12351637
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: July 8, 2025
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Rachel Elizabeth Johns, Palani Balu, Rob Burke, Beatrice Diana Darimont
  • COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY
    Publication number: 20250195676
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Application
    Filed: January 17, 2025
    Publication date: June 19, 2025
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
    Publication number: 20250171544
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 29, 2025
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Rachel Elizabeth JOHNS, Palani BALU, Rob BURKE, Beatrice Diana DARIMONT
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING
    Publication number: 20250170260
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 29, 2025
    Inventors: Arthur A. LEVIN, Andrew John GEALL, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Michael Caramian COCHRAN, Hanhua HUANG, Venkata Ramana DOPPALAPUDI, Rachel JOHNS
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING
    Publication number: 20250161344
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 22, 2025
    Inventors: Arthur A. LEVIN, Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, Hanhua HUANG, Rob BURKE
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
    Publication number: 20250152726
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 15, 2025
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Joel Daniel ARIAS, David Sai-Ho CHU, Michael Caramian COCHRAN, Rob BURKE, Philip KOVACH, Barbora MALECOVA