Abstract: Disclosed herein are two-wire communication systems and applications thereof. In some embodiments, a slave node transceiver for low latency communication may include upstream transceiver circuitry to receive a first signal transmitted over a two-wire bus from an upstream device and to provide a second signal over the two-wire bus to the upstream device; downstream transceiver circuitry to provide a third signal downstream over the two-wire bus toward a downstream device and to receive a fourth signal over the two-wire bus from the downstream device; and clock circuitry to generate a clock signal at the slave node transceiver based on a preamble of a synchronization control frame in the first signal, wherein timing of the receipt and provision of signals over the two-wire bus by the node transceiver is based on the clock signal.

Abstract: CD47+ disease cells such as cancer cells are treated using a combination of CD47 blockade drug and a histone deacetylase (HDAC) inhibitor. The anti-cancer effect of one drug enhances the anti-cancer effect of the other. Specific combinations include SIRP?Fc as CD47 blockade drug, and one of depsipeptide and romidepsin as HDAC inhibitor. These combinations are useful particularly to treat blood cancers including lymphomas, leukemias and myelomas.

Abstract: CD47? disease cells such as cancer cells are treated using a combination of CD47 blockade drug and a proteasome inhibitor. The anti-cancer effect of one drug enhances the 5 anti-cancer effect of the other. Specific combinations include SIRP?Fc as CD47 blockade drug, and one of bortezomib, ixazomib and carfilzomib as proteasome inhibitor. These combinations are useful particularly to treat blood cancers including lymphomas, leukemias and myelomas.

Abstract: Many processes for audio signal processing can benefit from voice activity detection, which aims to detect the presence of speech as opposed to silence or noise. The present disclosure describes, among other things, leveraging energy-based features of voice and insights on first and second formant frequencies of vowels to provide a low-complexity and low-power voice activity detector. A pair of two channels is provided whereby each channel is configured to detect voice activity in respective frequency bands of interest. Simultaneous activity detected in both channels can be a sufficient condition for determining that voice is present. More channels or pairs of channels can be used to detect different types of voices to improve detection and/or to detect voices present in different audio streams.

Abstract: A control system having packaged sets of control logic, referred to as templates. A template may be deployed in a system many times to solve a system's needs. Upon deployment, the user may need to perform many binding operations. The present system and approach may greatly reduce the labor involved in deploying control templates and in templates configuring a system of devices. Semantic tagging may be used. When designing a template, binding hints may be provided for each entity in the template that requires binding upon deployment. The binding hints may be used as a search predicate. When a template is deployed into a control space, a search query with binding hints for each bindable entity defined, may automatically be executed against the control space. If there is a single result for a bindable entity, then it may be automatically bound. If there are multiple results, a user may be prompted to choose from a results list.

Abstract: A home automation (HA) system may include HA operation devices and HA user interface devices for respective users. Each HA user interface device may be configured to wirelessly communicate with at least one of the HA operation devices. The HA system may also include HA hub devices configured to provide communications for the HA user interface devices and the HA operation devices. A cloud server may be configured to communicate with the HA hub devices, determine a needed maintenance operation for a given one of the HA operation devices, and communicate the needed maintenance operation to the given one of the HA operation devices. The cloud server may also be configured to duplicate communicating the needed maintenance operation to others of the HA operation devices.

Abstract: A home automation (HA) system to be used within a structure may include a communications network extending within the structure and HA operation devices within the structure. The HA system may also include HA user interface devices for respective users within the structure and HA hub devices within the structure to provide communications via the communications network for the HA user interface devices and the HA operation devices. Each HA hub device may have a processing capacity associated therewith and determine a shareable processing capacity for sharing with at least one other HA hub device based upon a current processing capacity and at least one of the HA operation devices. Each HA hub device may also communicate the amount of shareable processing capacity to another HA hub device and perform processing operations for the other HA hub device based upon the communicated shareable processing capacity.

Abstract: Disclosed herein are two-wire communication systems and applications thereof. In some embodiments, a slave node transceiver for low latency communication may include upstream transceiver circuitry to receive a first signal transmitted over a two-wire bus from an upstream device and to provide a second signal over the two-wire bus to the upstream device; downstream transceiver circuitry to provide a third signal downstream over the two-wire bus toward a downstream device and to receive a fourth signal over the two-wire bus from the downstream device; and clock circuitry to generate a clock signal at the slave node transceiver based on a preamble of a synchronization control frame in the first signal, wherein timing of the receipt and provision of signals over the two-wire bus by the node transceiver is based on the clock signal.

Abstract: A home automation (HA) system may include addressable HA devices each having associated therewith a respective device capability, device configuration, and device state. The HA system may also include a cloud message queue controller and a cloud message queue memory coupled thereto in the cloud for storing the device configurations, device capabilities, and device states for the addressable HA devices. The HA system may also include a home device message queue controller and a home device message queue memory coupled thereto for storing the device configurations, device capabilities, and device states for the addressable HA devices. The cloud message queue controller and the home device message queue controller may synchronize device configurations, device capabilities, and device states for the addressable HA devices.

Abstract: Optical assemblies, interconnection substrates and methods of forming optical links are disclosed. In one embodiment, an optical assembly includes a first waveguide substrate, a second waveguide substrate, and an interconnection substrate having a first end face, a second end face, and a laser written waveguide. The first waveguide substrate is coupled to the first end face of the interconnection substrate, and the first waveguide is optically coupled to the laser written waveguide. The laser written waveguide terminates at the second end face of the interconnection substrate. The second waveguide substrate is coupled to the second end face of the interconnection substrate such that the second waveguide is optically coupled to the laser written waveguide at the second end face.

Abstract: Activity monitors and smart watches utilizing optical measurements are becoming widely popular, and users expect to get an increasingly accurate estimate of their heart rate (HR) from these devices. These devices are equipped with a light source and an optical sensor which enable estimation of HR using a technique called photoplethysmography (PPG). One of the main challenges of HR estimation using PPG is the coupling of motion into the optical PPG signal when the user is moving randomly or exercising. The present disclosure describes a computationally feasible and fast HR estimation algorithm to be executed at instances of little or no motion. Resulting HR readings may be useful on their own, or be provided to systems that monitor HR continuously to prevent the problem of such systems being locked on an incorrect HR for long periods of time. Implementing techniques described herein leads to more accurate HR measurements.

Abstract: Embodiments of a system and method for sharing media content are generally described herein. A method may include receiving, from a first clearing device, a first indication of approval for sharing media content from an originating device, the first indication identifying the originating device, sending an encryption key for sharing the media content to the originating device, receiving an encrypted file, the encrypted file including the media content encrypted using the encryption key from the originating device, sending the encryption key and the encrypted file to a second clearing device, receiving, from the second clearing device, a second indication of approval for viewing media content, the second indication identifying a destination device, and sending, in response to receiving the second indication of approval, the encryption key and the encrypted file to the destination device.

Abstract: Embodiments of the provided technology relate to methods, devices, and systems that drive a transfer of the digital profile of residual limb contours to a thermoplastic article such as a prosthetic socket strut. A method of reforming a thermoplastic article to assume a desired shape, such as a contour that replicates or is complementary to the contour of a body portion, may include heating a thermoplastic article to render the article malleable. The method may further include placing the thermoplastic article against a molding surface having a desired shape that replicates the portion of the body part. Next, the thermoplastic article may be pressed against the molding surface with a compliant molding press to reform at least a portion of the article into the desired shape. The reformed thermoplastic article may then be removed from the molding surface, the article retaining the desired shape after removal.

Abstract: Blockade of the CD47/SIRPa pathway depletes cancer cells. This anti-cancer activity is enhanced when macrophage stimulating agents are used in combination with the CD47 blockade drug. This anti-cancer combination therapy is particularly effective when the CD47 blockade drug is SIRPaFc.

Abstract: The present invention relates in one aspect to a method of detecting diaphragm excursion of an electrodynamic loudspeaker. The method comprises steps of generating an audio signal for application to a voice coil of the electrodynamic loudspeaker and adding a high-frequency probe signal to the audio signal to generate a composite drive signal. The method further comprises a step of applying the composite drive signal to the voice coil through an output amplifier and detecting a modulation level of a probe signal current flowing through the voice coil.

Abstract: A mattress protector includes a unitary flat sheet for covering a surface of a mattress and providing a liquiphobic barrier for the surface. The flat sheet has four corners with cuts in the sheet proximal to and following a contour of each corner (or alternatively following the contour of each corner and laterally from corner to corner) to form corner attachment members for extending from the surface and under the mattress, thereby securing the sheet to the mattress.

Abstract: A home automation (HA) system may include addressable HA devices each having associated therewith a respective device capability, device configuration, and device state. The HA system may also include a cloud message queue controller and a cloud message queue memory coupled thereto in the cloud for storing the device configurations, device capabilities, and device states for the addressable HA devices. The HA system may also include a home device message queue controller and a home device message queue memory coupled thereto for storing the device configurations, device capabilities, and device states for the addressable HA devices. The cloud message queue controller and the home device message queue controller may synchronize device configurations, device capabilities, and device states for the addressable HA devices.

Abstract: An apparatus for light diffraction and an organic light emitting diode (OLED) incorporating the light diffraction apparatus is disclosed. An apparatus for light diffraction may comprise an optional planarization layer, a transparent substrate, a waveguide layer. The planarization layer may have a refractive index of ns. The transparent substrate may have a refractive index of ng. The waveguide layer may have a refractive index nw distributed over of the transparent substrate. The waveguide layer may comprise a binding matrix, at least one nanoparticle. The waveguide layer may be interposed between the transparent substrate and the optional planarization layer.

Abstract: Data is received describing a local model of a first device generated by the first device based on sensor readings at the first device and a global model is updated that is hosted remote from the first device based on the local model and modeling devices in a plurality of different asset taxonomies. A particular operating state affecting one or more of a set of devices deployed in a particular machine-to-machine network is detected and the particular machine-to-machine network is automatically reconfigured based on the global model.