Abstract: The INTERIOR COMFORT HVAC USER-FEEDBACK CONTROL SYSTEM AND APPARATUS transforms qualitative feedback received from a user/occupant into a “comfort map,” or modifications thereto, a comfort map being defined at least in part by one or more comfort event windows. The comfort map data is used to determine a temperature setpoint sequence that avoids regions of the map corresponding to known and/or predicted regions of user discomfort.

Abstract: Methods of isolating nucleic acid and protein molecules from a single formalin-fixed, paraffin-embedded (FFPE) tissue sample section include lysing the cells of the tissue sample section, alkylating, reducing, and enzymatically digesting proteins in the lysate, and separating nucleic acids present in the lysate from the digested proteins. Cell lysis is performed under conditions that permit extraction of DNA, RNA, and proteins that are suitable for genomic and proteomic analysis. In particular, the buffer conditions, reaction time, and temperature of the lysis reaction are such that a suitable amount of DNA, RNA, and proteins are released and in stable condition for separation and proteogenomic analysis. Systems for performing methods include reagents and apparatus for performing steps of the method. Panels for detecting the presence and level of expression of peptides to differentiate between disease states include a plurality of peptides.

Abstract: A fastener includes a pin member, a swage collar, and a nut. The pin member includes a shank portion having first and second ends and a threaded portion including an external thread. The swage collar has first and second ends and is adapted to be installed on the pin member and swaged onto the external thread of the pin member. The second end of the swage collar is positioned distal from the first end of the pin member when the swage collar is installed on the pin member. The nut is adapted to be installed on the pin member and has first and second ends and an internal thread adapted to engage the external thread of the pin member. When the nut is installed on the pin member, the nut is adapted to engage the swage collar such that the swage collar is retained on the pin member before swaging.

Abstract: This invention relates to quinazoline compounds of Formula (I) which are inhibitors of the histone lysine methyltransferase (HKMTase) EZH2, and to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of EZH2 provides a therapeutic or prophylactic effect.

Abstract: Coat-in-place assemblies and methods to provide an aesthetically pleasing sprinkler assembly. A coat-in-place assembly includes a sprinkler body having a proximal portion and a distal portion, a thermally responsive trigger disposed adjacent the distal portion; and an escutcheon centered about the distal portion of the sprinkler body to define a void between the sprinkler axis and the escutcheon. A coating-inhibiting-cap encloses and protects the thermally responsive trigger between the sprinkler body and the cap. The cap extends into the void and is radially spaced inward relative to the escutcheon so as expose surfaces of the escutcheon for coating.

Abstract: Systems for examining a route inject one or more electrical examination signals into a conductive route from onboard a vehicle system traveling along the route, detect one or more electrical characteristics of the route based on the one or more electrical examination signals, and detect a break in conductivity of the route responsive to the one or more electrical characteristics decreasing by more than a designated drop threshold for a time period within a designated drop time period. Feature vectors may be determined for the electrical characteristics and compared to one or more patterns in order to distinguish between breaks in the conductivity of the route and other causes for changes in the electrical characteristics.

Abstract: A voice command definition file (VCDF) declaratively defines voice commands for an application. For example, the VCDF may include definitions for: voice commands; one or more phrases/utterances that may be said to execute each of the commands; a navigation location to navigate to within the application (e.g. a page); phrase lists containing items that may be used as a parameter in a voice command; examples; feedback; and the like. A user may say a single utterance to launch the application, navigate to the associated location of the command and execute the command. The VCDF may define multiple ways to listen for a particular command. The VCDF may be edited/defined by a user and may include a user friendly name for an application. A speech engine loads the VCDF for use such that it may recognize the commands associated with an application. The definitions may be updated during runtime.

Abstract: A method for operating a wireline winch configured to convey a wireline coupled to a downhole tool disposed in a borehole penetrating the earth includes: receiving a first cumulative surface wireline tension limit for downhole wireline components; calculating a second cumulative surface wireline tension limit for surface components using wireline speed and surface equipment data; combining the first and the second cumulative surface wireline tension limits to provide a total cumulative surface wireline tension limit as a function of depth; presenting the total cumulative surface wireline tension limit as a function of depth and operating wireline tension values as a function of depth for the downhole tool to a user; performing an assessment of the operating wireline tension values as a function of depth versus the total cumulative surface wireline tension limit as a function of depth; and operating the wireline winch using the assessment and a winch controller.

Abstract: An aircraft fuselage (4) comprising: an aircraft door or access panel (2) comprising a receiving element (14); and locking apparatus for securing the aircraft door/panel (2) in an opening of aircraft fuselage (4), the locking apparatus comprising: a shaft (8); a mounting member (10) for mounting the shaft (8) to the fuselage (4); securing means (12) fixedly mounted to the shaft (8) and arranged such that rotation of the shaft (8) about its longitudinal axis moves the securing means (12) from being not coupled to a receiving element (14) to being coupled to a receiving element (14) or vice versa; a locking member (52) for coupling to the shaft (8) such that rotation of the shaft (8) causes movement of the locking member (52); and fixing means for fixedly attaching the locking member (52) to the aircraft fuselage (4) thereby preventing rotation of the shaft (8).

Abstract: Systems and methods for the categorization of websites are presented. A website is categorized using one or a combination of its domain name and its web page content. The domain name is tokenized, and the tokens compared to categories in a category structure to determine probabilities that the token belongs to each category. Combinations of tokens are similarly compared to the categories. A category may be determined with reference to a vector space in which a training set of websites having known categories is converted according to a methodology into reference vectors containing keyword frequencies. A target website is converted to a target vector using the same methodology, and a distance score of the target vector to each reference vector is calculated. The website represented by the target vector is assigned the category of the reference vector having the lowest distance score.

Abstract: Communications apparatus has a short range wireless radio frequency communicator (1301a) capable of at least one of seeking to initiate short range communication by transmitting an RF signal and of responding to such initiation so that communication between two short range wireless radio frequency communicators occurs when an antenna of a short range wireless radio frequency communicator seeking to initiate communication by transmitting an RF signal is in range of or comes into range of the antenna of another short range wireless radio frequency communicator responsive to such initiation so that the magnetic field of the RF signal transmitted by the short range wireless radio frequency communicator seeking to initiate communication is inductively coupled to the antenna of the short range wireless radio frequency communicator responsive to such initiation to enable communication of at least one of power and data between the short range wireless radio frequency communicators.

Abstract: A fishing weight (100) that includes an oblong body (104), for instance in the shape of a football. A passage (116) extends through the oblong body (104) to allow fishing line (140) to extend through the passage (116). The passage (116) is positioned so that the fishing line (140) pulls the fishing weight (100) in a “sideways” orientation through the water. In one embodiment, the passage (116) proceeds other than linearly through the oblong body (104) of the fishing weight (100).

Abstract: A system for testing or calibrating a part, the system including: a plurality of test stations, each test station including a container and a clamping mechanism, wherein the clamping mechanism includes: a clamp frame including: two clamp plates; a plurality of clamp bars configured to securely hold the clamp plates at a distance relative to each other; a seal manifold provided on one of the two clamp plates; and a clamping module, located opposite the seal manifold on another of the two clamp plates, wherein the clamping module includes: a plurality of pistons to hold the part against the seal manifold for the test operation; and at least one cleaning station comprising a spin mechanism for spinning the part to remove excess fluid; and a robotic system for moving individual parts to and from the plurality of test stations and to and from the at least one cleaning station.

Abstract: A system and method for treating a portion of a wellbore that includes a bottom hole assembly (BHA) connected to a work string. The BHA includes a packing element movable between an unset position and a set position and a locator device movable between retracted position and expanded positions. The locator device may be a locator collet. The locator collet may be expanded by a cone movable with respect to the collet. The expanded locator device is configured to engage a profile in a ported tubular within the wellbore. The engagement between the locator device and the profile selectively prevents further movement of the BHA and provides an indication of the location the BHA. The packing element may then be actuated and the wellbore treated through a port in the ported tubular. The BHA may then be moved to a different ported housing to treat another portion of the wellbore.

Abstract: A system, method, and apparatus are discussed for a passive optical camera-based system to detect a presence of one or more vehicles with one or more cameras. A detection algorithm is applied to recognize of the presence of the one or more vehicles using one or more imaging processors and the one or more cameras to detect fluctuations in light intensity from scattered light and/or reflections off of that vehicle. Those scattered light and/or reflections are captured in images contained in a set of frames from the one or more cameras.

Abstract: Aspects of the present disclosure involve a reservation system that monitors, purchases airline tickets and/or airline reservations automatically and in real-time. One or more graphical-user interfaces are generated that reduce the time it takes for a user to identify and reserve and airline ticket.

Abstract: A fastener includes a pin member, a swage collar, and an insert. The pin member includes an elongated shank portion, a head, a threaded portion having an external thread and a plurality of lock grooves, and a pull portion. The swage collar includes a shank having a flange and a through bore with a first interior portion extending from a first end of the collar to a stepped portion and forming a first inner wall having a first inner diameter, and a second interior portion extending from the stepped portion to a second end of the collar and forming a second inner wall having a second inner diameter. The insert includes a through bore forming an inner wall that has an internal thread adapted to engage the external thread of the pin member.

Abstract: Systems and methods for examining a route inject one or more electrical examination signals into a conductive route from onboard a vehicle system traveling along the route, detect one or more electrical characteristics of the route based on the one or more electrical examination signals, apply a filter to the one or more electrical characteristics, and detect a break in conductivity of the route responsive to the one or more electrical characteristics decreasing by more than a designated drop threshold for a time period within a designated drop time period. Feature vectors may be determined for the electrical characteristics and compared to one or more patterns in order to distinguish between breaks in the conductivity of the route and other causes for changes in the electrical characteristics.

Abstract: A frame error correction circuit may identify and correct errors in data frames provided to a receiver as part of a diversity communications scheme. The frame error correction circuit may further align the data frames so that the data frames can be compared. The frame error correction circuit may perform a bit-wise comparison of the data frames and identify inconsistent bit positions where bits in the data frames differ from one another. Once inconsistent bit positions have been identified, the frame error correction circuit may access a permutation table of permutations of bits at the inconsistent bit positions. In some implementations, the frame error correction circuit uses the permutation table to reassemble permutations of the data frames. In various implementations, the frame error correction circuit performs a CRC of each permutation of the data frames, and provides a valid permutation to a network.

Abstract: A bowtie whose frontal construction is a photorealistic representation of an actual specific species of open-winged moth in a manner that looks precise to the naked eye which a person can wear on one's neck or collar in the manner that one normally wears a bowtie.