Abstract: A flat tire safety system, having: (a) a pair of elongated semicircular members dimensioned to wrap around a tire rim and be positioned within a tire; and (b) a pair of clamping assemblies, each clamping assembly securing an end of the first elongated semicircular member to the end of the second elongated semicircular member, wherein each clamping assembly has: (i) a housing, (ii) a double-headed bolt passing through the housing, (iii) a tightening bolt mounted in the housing, wherein rotating the tightening bolt turns the double-headed bolt, (iv) a ratchet on the housing for permitting the tightening bolt to rotate in a tightening direction and preventing the tightening bolt from rotating in a loosening direction, (v) a release on the housing for selectively permitting the tightening bolt to rotate in the loosening direction, and (c) a pair of anchors, wherein each anchor is embedded in the end of one of the elongated semicircular members, and wherein one end of the double-headed bolt passes through each of

Abstract: In an example, a method can include segmented image volume data for at least one anatomic structure, wherein the segmented image volume data includes a 3-D image volume that includes the at least one anatomic structure. The method can include searching outward from a computed centerline for the at least one anatomic structure to detect a surface of one or more regions of interest of the at least one anatomic structure by evaluating values associated with voxels representing the 3-D image volume that includes the at least one anatomic structure relative to a threshold. The method can further include isolating the one or more regions of interest of the at least one anatomic structure in response to the searching and generating a region of interest model based on the one or more isolated regions of interest.

Abstract: The present disclosure relates generally to eukaryotic initiation factor 2B modulators, or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or prodrug thereof, and methods of making and using thereof.

Abstract: The present disclosure relates generally to eukaryotic initiation factor 2B modulators, or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or prodrug thereof, and methods of making and using thereof.

Abstract: This invention relates to the compound (2R)-2-(6-{5-chloro-2-[(oxan-4-yl)amino]pyrimidin-4-yl}-1-oxo-2,3-dihydro-1H-isoindol-2-yl)-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide, and in particular to novel physical forms of the compound, a process for preparing the compound and synthetic intermediates for use in the process, and novel formulations containing the compound, as well as therapeutic uses of the compound.

Abstract: Some embodiments of the present disclosure disclose methods and systems for cataloguing provenances of watches and for authenticating watches based on the catalogue. In some embodiments, an image of a face of a watch and a video of a hand of the watch moving across the face of the watch may be obtained. Further, a set of scale-invariant features of the face may be extracted using a feature transformation algorithm. Further, a motion curve tracing the hand of the watch moving across the face of the watch may be extracted using a visual motion tracker. In addition, the physical attributes of the watch may also be obtained. In some embodiments, the feature transformation features, the motion curve and the physical attributes may be stored in a database configured to catalogue the provenance of watches, which can also be used to authenticate watches.

Abstract: In an example, an apparatus for access regulation of peripheral devices may include a processor and a communication interface to communicate to a peripheral device and to the processor. The processor may identify a pattern associated with receiving input data from a first peripheral device, wherein the pattern includes a keystroke rate, a delay in a keystroke pattern, a keystroke pressure, or a combination thereof. Similarly, the processor may, in response to detecting enumeration of a second peripheral device coupled to the apparatus, compare particular input data received from the second peripheral device with the pattern, and regulate access of the second peripheral device to the apparatus, based on the comparison.

Abstract: The present invention relates to spiral wind turbines and an energy-harnessing system. The system features a plurality of spiral wind turbines adapted to collect drag energy of moving vehicles and for converting the collected energy into electricity. The spiral wind turbines can also be installed for collecting air flow energy from heating vents on rooftops, smokestacks or similar structures. The system uses wind energy along with captured moving air or heated air energy for producing electric power using electric generators and storing same using storage batteries. The turbines are vertically rotating, and the method of attachment/installation will depend on the type of turbine and the location. The system allows federal, state, and local governments, as well as others, to generate electricity passively.

Abstract: The present disclosure relates generally to eukaryotic initiation factor 2B modulators, or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers, or prodrug thereof, and methods of making and using thereof.

Abstract: Early detection of tumors is a major determinant of survival of patients suffering from tumors, suffering from these cancers, including bladder tumors. Genetic markers can be highly and consistently accumulated in bladder tumor tissue, other tumor tissue, and/or in urine of patients having bladder cancer. Detection of these markers can be an effective diagnostic tool to guide therapy. Detection and quantification of a plurality of bladder tumor markers using polymerase chain reaction methods can increase the sensitivity and specificity of detection of bladder cancer, provide methods for determining the stage and type of bladder cancer, and provide specific methods for treatment.

Abstract: In an example, a system includes a firmware controller to initiate a SM execution mode of the system. The firmware controller scans memory for a process pool tag. The firmware controller compares the process pool tag to a set of operating system process pool tags and detects a coherency discrepancy between the process pool tag and the set of operating system process pool tags. The firmware controller exits the SM execution mode of the system.

Abstract: The present disclosure relates generally to eukaryotic initiation factor 2B modulators, or a pharmaceutically acceptable salt, stereoisomer, mixture of stereoisomers or prodrug thereof, and methods of making and using thereof.

Abstract: Methods and systems described in this disclosure allow customers to personalize their phone experience when calling into an organization. In some embodiments, customers who may benefit from this service are identified based on the content of the customer's previous or current phone calls to the organization. The identified customers may be invited to enroll and to provide preferences for a customized Interactive Voice Response experience. In some embodiments, the customer can elect to hear the balances of one or more of his accounts without going through a phone menu or asking a representative to look up the relevant amounts. Once enrolled, when the customer dials into the organization and upon successful authentication, the organization proactively states the customer's account balances with no further customer request.

Abstract: Systems and methods for continuously monitoring a workcell during operation of industrial machinery are disclosed. The system may comprise a safety system that includes at least one sensor and supporting software and/or hardware for acquiring image data associated with the workcell; a monitoring system for detecting a parameter value associated with the safety system; and a controller configured to determine a status of the safety system based at least in part on the detected parameter value and cause an alert to be issued if the status of the safety system does not satisfy a target objective.

Abstract: The present invention relates to novel oxadiazoles of formula I, or the N-oxides and/or their agriculturally useful salts and to their use for controlling phytopathogenic fungi, or to a method for combating phytopathogenic harmful fungi, which process comprises treating the fungi or the materials, plants, the soil or seeds to be protected against fungal attack, with an effective amount of at least one compound of formula I, or an N-oxide, or an agriculturally acceptable salt thereof; the present invention also relates to mixtures comprising at least one such compound of formula I and at least one further pesticidally active substance selected from the group consisting of herbicides, safeners, fungicides, insecticides, and plant growth regulators; and to agrochemical compositions comprising at least one such compound of formula I and to agrochemical compositions further comprising seeds.

Abstract: Methods and systems described in this disclosure allow customers to quickly be authenticated. In some embodiments, a device and a user verifier are associated with a user profile. When a call is received from the device, the user may be requested to input the user verifier. After verifying that the device is unique to the user and that the user verifier matches the user verifier associated with the user profile, the user may be authenticated to the call or activity.

Abstract: A method of forming a ceramic-metal composite part is described herein. The method includes maintaining molten metal in an interior of a housing in a liquefied state, the interior including a first chamber, a second chamber, and a port defined therebetween. The method further includes sealing the port such that the molten metal in the first chamber is maintained at a first liquid level, suspending a part at a height within the first chamber above the first liquid level, forming a pressure differential between the first chamber and the second chamber, unsealing the port such that molten metal from the second chamber flows into the first chamber, and resealing the port when the molten metal in the first chamber reaches a second liquid level such that the ceramic part is submerged in the molten metal.

Abstract: This invention relates to prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for colorectal cancer. Specifically, this invention relates to the use of genetic markers for the prediction of the prognosis of cancer, such as colorectal cancer based on signatures of genetic markers. In various aspects, the invention relates to a method of predicting the likelihood of long-term survival of a cancer patient, a method of determining a treatment regime for a cancer patient, a method of preparing a treatment modality for a cancer patient, among other methods as well as kits and devices for carrying out these methods.

Abstract: The present invention relates to trifluoromethyloxadiazoles of the formula (I), or the N-oxides, or the agriculturally useful salts thereof; to a process for preparing compounds of the formula (I); to intermediates which are useful in the preparation of compounds of the formula (I); to the use of compounds of the formula (I) for controlling phytopathogenic fungi; to a method for combating phytopathogenic harmful fungi, which process comprises treating the fungi, the plants, the soil or seeds to be protected against fungal attack, with an effective amount of at least one compound of the formula (I), or an N-oxide, or an agriculturally acceptable salt thereof; and to agrochemical compositions comprising at least one compound of the formula (I), or an N-oxide, or an agriculturally acceptable salt thereof; and to agrochemical compositions further comprising seeds.

Abstract: This invention relates to the compound (2R)-2-(6-{5-chloro-2-[(oxan-4-yl)amino]pyrimidin-4-yl}-1-oxo-2,3-dihydro-1H-isoindol-2-yl)-N-[(1S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl]propanamide, and in particular to novel physical forms of the compound, a process for preparing the compound and synthetic intermediates for use in the process, and novel formulations containing the compound, as well as therapeutic uses of the compound.