Abstract: A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hydrophobicity modifying agent, a pH modifying agent and a buffer. A method of treating a patient having pulmonary arterial hypertension includes providing a patient a dry powder inhaler, providing the patient at least one capsule for use in the dry powder inhaler, the capsule including at least 25 micrograms of treprostinil.

Abstract: In accordance a method for storing a dataset, the dataset may be split into fragments that are distributed among different nodes of a network for storage. The fragments may then be retrieved as and when needed and re-assembled. The method allows multiple different fragments to be stored and re-assembled on demand. The dataset is initially stored in a user computing device in communication with a data storage system and a custodial entity. The fragments are stored so that no single computing entity in the storage system or the custodian ever contains or gains knowledge of all the fragments. Additionally, the user computing device that was initially in possession of the dataset and which caused the fragments to be stored in the storage system may be replaced with different user computing devices without losing the capability of storing and re-assembling the user data on demand by the replacement user computing device.

Abstract: A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hydrophobicity modifying agent, a pH modifying agent and a buffer. A method of treating a patient having pulmonary arterial hypertension includes providing a patient a dry powder inhaler, providing the patient at least one capsule for use in the dry powder inhaler, the capsule including at least 25 micrograms of treprostinil.

Abstract: A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hydrophobicity modifying agent, a pH modifying agent and a buffer. A method of treating a patient having pulmonary arterial hypertension includes providing a patient a dry powder inhaler, providing the patient at least one capsule for use in the dry powder inhaler, the capsule including at least 25 micrograms of treprostinil.

Abstract: Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter.

Abstract: A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hydrophobicity modifying agent, a pH modifying agent and a buffer. A method of treating a patient having pulmonary arterial hypertension includes providing a patient a dry powder inhaler, providing the patient at least one capsule for use in the dry powder inhaler, the capsule including at least 25 micrograms of treprostinil.

Abstract: A vibration damping system for a turbine nozzle or blade includes a body opening extending through a body of the turbine nozzle or blade between a tip end and a base end thereof. Elongated vibration damping element is disposed in the body opening and includes an elongated body having a first, free end and a second end fixed relative to one of the base end and the tip end. At least one wire mesh member surrounds the elongated body. The wire mesh member(s) frictionally engage with an inner surface of the body opening to damp vibration. A related method is also disclosed.

Abstract: A biodegradable unisex disposable safety razor includes an ergonomic handle and a fixed head arranged on one end of the handle. The head includes a skin contacting surface, an internal process cavity with a single blade having a single cutting edge. The blade communicates with four independent passages located on the head. The device, which functions with no moving parts and/or electronics has an integrated and enhanced; skin lubrication system, an acoustic alert method for achieving an optimal shave, a method to alternate the shaving blade material temperature, dependent care assist functionality, a fully internal surface wetting antibacterial protection method, an external user safety protection guard, a post shave debris clean-out in conjunction to a fully internal material surface dry-out sanitization system aimed at improving the devices overall hygiene.

Abstract: Rotor blades, vibrational dampening elements, and methods are provided. A rotor blade includes a platform, a shank extending radially inward from the platform, and an airfoil extending radially outward from the platform. One or more fluid chambers are defined within the rotor blade. Glass is disposed within each fluid chamber of the one or more fluid chambers. A mass is disposed within each fluid chamber of the one or more fluid chambers. The mass is movable within the glass relative to the airfoil.

Abstract: Described are shoes for ball sports including an upper having an outer surface. An actuator is configured to change at least one surface property of a portion of the outer surface of the upper, and a sensor is configured to be sensitive to movements of the shoe. A processing unit is connected to the actuator and the sensor and configured to process sensor data retrieved from the sensor and to cause the actuator to change the at least one surface property of the portion of the outer surface of the upper if a predetermined event is detected in the sensor data.

Abstract: Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter.

Abstract: Described are shoes for ball sports including an upper having an outer surface. An actuator is configured to change at least one surface property of a portion of the outer surface of the upper, and a sensor is configured to be sensitive to movements of the shoe. A processing unit is connected to the actuator and the sensor and configured to process sensor data retrieved from the sensor and to cause the actuator to change the at least one surface property of the portion of the outer surface of the upper if a predetermined event is detected in the sensor data.

Abstract: A method for communicating information relating to test results of a user includes obtaining test results of a user. An assertion is derived from the test results of the user. The test results are input to a pre-provisioned first algorithm. The assertion is encapsulated in a first data object by a PGE that controls an environment in which the first algorithm is executed. A first proof is generated which is configured to be usable to verify that the first algorithm used the test results to produce the assertion when provided to a PVE along with the first data object. The test results itself are excluded from the first proof and the first data object such that privacy of the test results is maintained. The first proof and the first data object are communicated to a receiving communication device from an enterprise communication device associated with the user and an enterprise.

Abstract: A method for sharing information has an assertion associated therewith such that the receiving communication device is able to verify the assertion without the sender revealing underlying data demonstrating the validity of the assertion. The assertion is derived from underlying data input to a pre-provisioned first algorithm. The assertion is encapsulated in a first data object by a PGE that controls an environment in which the first algorithm is executed. A first proof is generated that is configured to verify that the first algorithm used the underlying data to produce the assertion when provided to a PVE along with the first data object. The underlying data is excluded from the first proof and the first data object such that privacy of the underlying data is maintained. The information, the first proof and the first data object are sent to the receiving communication device from the sending communication device.

Abstract: Seed sowing apparatus comprising: a frame defining a leading part supporting a soil opening stage and a trailing part supporting a soil closing stage trailing the soil opening stage, wherein the soil opening stage comprises a plurality of laterally spaced seeding units, each seeding unit comprising a soil opening member associated with a respective seed delivery outlet connected to a seed source, wherein each seeding unit is configured to form a respective seeded trench in the ground when the apparatus is in use driven through soil in a forward direction of travel; wherein the soil closing stage comprises a plurality of laterally spaced soil deflection members each associated with a respective one of the seeding units, each soil deflection member being spaced laterally from the soil opening member of its respective seeding unit and configured to deflect soil toward the seeded trench formed by the seeding unit.

Abstract: A nozzle for a turbine system includes an airfoil, an inner sidewall, and an outer sidewall. Each of the inner sidewall and outer sidewall includes a peripheral edge defining a pressure side slash face, a suction side slash face, a leading edge face, and a trailing edge face. At least one of the inner sidewall pressure side slash face, the inner sidewall suction side slash face, the outer sidewall pressure side slash face, or the outer sidewall suction side slash face includes a first swept surface extending at a first angle relative to a nominal slash face angle and a second swept surface extending at a second angle relative to the nominal slash face angle. The first and second swept surfaces meet at an arc having a peak that is circumferentially aligned with a stiffening member extending circumferentially on a respective sidewall.

Abstract: Provided herein are genetic markers and a coding sequence associated with a low- or ultra-low anatabine trait in tobacco.

Abstract: A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hydrophobicity modifying agent, a pH modifying agent and a buffer. A method of treating a patient having pulmonary arterial hypertension includes providing a patient a dry powder inhaler, providing the patient at least one capsule for use in the dry powder inhaler, the capsule including at least 25 micrograms of treprostinil.

Abstract: Systems and techniques described herein are concerned with providing supervisory control of computer programs. In particular, a method for executing application code defining a computer program includes providing a “kill switch” to the operator, which allows the operator to disable the computer program. The kill switch is configured so that the computer program is incapable of over-riding it.

Abstract: Systems and techniques described herein are concerned with providing supervisory control of computer programs. In particular, a method for executing application code defining a computer program includes providing a “kill switch” to the operator, which allows the operator to disable the computer program. The kill switch is configured so that the computer program is incapable of over-riding it.