Abstract: Provided herein are genetic markers and a coding sequence associated with a low- or ultra-low anatabine trait in tobacco.

Abstract: A system, such as a system of a computing resource service provider, detects changes to a pipeline template package that encodes information associated with application code and infrastructure that may be utilized as part of deploying the application code in stages of a pipeline. An infrastructure template that is usable to provision an execution environment may be generated for a corresponding stage of the development, and may be utilized as part of a process for provisioning an execution environment which may, for example, run tests to verify the quality of the application code.

Abstract: In a method for recording a transaction between first and second transacting network nodes associated with a global blockchain is provided. The transacting nodes are associated with a selected sub-chain of the global blockchain. The selected sub-chain is selected from among a plurality of sub-chains of the global sub-chain. In response to the first transacting node causing cryptocurrency to be sent to a first public address associated with the second transacting node as part of a transaction between the first and second transacting nodes, the given transaction is recorded in the selected sub-chain. Subsequent to recording the given transaction, the transaction recorded on the global blockchain using a second public address of the second transacting network node. The recording is performed using an atomic commit process that prevents the first and second transacting nodes from conducting any other transactions while the given transaction is being recorded on the global blockchain.

Abstract: A method for communicating information relating to test results of a user includes obtaining test results of a user. An assertion is derived from the test results of the user. The test results are input to a pre-provisioned first algorithm. The assertion is encapsulated in a first data object by a PGE that controls an environment in which the first algorithm is executed. A first proof is generated which is configured to be usable to verify that the first algorithm used the test results to produce the assertion when provided to a PVE along with the first data object. The test results itself are excluded from the first proof and the first data object such that privacy of the test results is maintained. The first proof and the first data object are communicated to a receiving communication device from an enterprise communication device associated with the user and an enterprise.

Abstract: In devices that determine levels of substance use, a substance level in a test sample provided to the testing device by a test subject is determined. A sequence of images are captured to include a portion of the face of the test subject providing the test sample and a display of the testing device. A value indicative of the substance level detected within the test sample is determined. A validity indicator indicating validity of the value indicative of the substance level is determined. A current location is determined. The value indicative of the substance level, the validity indicator, and the current location are sent to a remote server.

Abstract: A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hydrophobicity modifying agent, a pH modifying agent and a buffer. A method of treating a patient having pulmonary arterial hypertension includes providing a patient a dry powder inhaler, providing the patient at least one capsule for use in the dry powder inhaler, the capsule including at least 25 micrograms of treprostinil.

Abstract: A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hydrophobicity modifying agent, a pH modifying agent and a buffer. A method of treating a patient having pulmonary arterial hypertension includes providing a patient a dry powder inhaler, providing the patient at least one capsule for use in the dry powder inhaler, the capsule including at least 25 micrograms of treprostinil.

Abstract: We describe instruments, and cartridges therefor, for processing droplets of water in oil-in-water emulsions, the droplets containing biological entities such as cells. In one embodiment a method of such processing comprises: providing a plurality of the entities in a fluid: preparing a droplet from said fluid: determining whether said droplet contains one or more entities of said plurality of entities, or whether said droplet does not contain a said entity; sorting said droplet dependent on an outcome of said determination; and dispensing said sorted droplet into a reservoir, wherein said dispensing comprises: identifying said sorted droplet for dispensing; extracting said sorted droplet from a first fluidic flow path of said fluid by transferring said sorted droplet from said first fluidic flow path into a second fluidic flow path; and ejecting said sorted droplet from said second fluidic flow path into said reservoir by applying pressure to said second fluidic flow path.

Abstract: An improved cake cover for protecting and securing a cake, or other food item. The cake cover is preferably comprised of a washable enclosure having a plurality of receptacles positioned thereon for receipt of a plurality of interchangeable inserts, thereby allowing the user to customize the appearance and function of the cake cover. The plurality of inserts may include, without limitation, a candle holding insert, a light emitting insert and a sound emitting insert. An outer surface of the cake cover may further comprise decorative texturing that mimics the appearance of a traditionally baked cake, and/or may be constructed of a transparent or translucent material to enable the cake stored therein to be viewed through the cake cover. Finally, the cake cover may further comprise a securing means for securing the cover to a surface.

Abstract: A nozzle for a turbine system includes an airfoil, an inner sidewall, and an outer sidewall. Each of the inner sidewall and outer sidewall includes a peripheral edge defining a pressure side slash face, a suction side slash face, a leading edge face, and a trailing edge face. At least one of the inner sidewall pressure side slash face, the inner sidewall suction side slash face, the outer sidewall pressure side slash face, or the outer sidewall suction side slash face includes a first swept surface extending at a first angle relative to a nominal slash face angle and a second swept surface extending at a second angle relative to the nominal slash face angle. The first and second swept surfaces meet at an arc having a peak that is circumferentially aligned with a stiffening member extending circumferentially on a respective sidewall.

Abstract: Instruments and cartridges for processing droplets in emulsions containing biological entities such as cells. A method of such processing comprises providing a plurality of the entities in a fluid; preparing a droplet from the fluid; determining whether the droplet contains one or more entities of said plurality of entities, or whether said droplet does not contain a said entity; sorting said droplet dependent on an outcome of the determination; and dispensing the sorted droplet into a reservoir. The dispensing may comprise identifying and extracting the sorted droplet from a first fluidic flow path of said fluid by transferring the sorted droplet from into a second fluidic flow path and then ejecting the sorted droplet into a reservoir by applying pressure to the second fluidic flow path. The droplet contents may be tracked so that the contents of an individual droplet can be sorted, selectively dispensed, and retrieved.

Abstract: A seeding unit comprising: a support; a soil opening member mounted to the support; and a seed delivery outlet, defining an exit aperture for releasing seed; wherein the soil opening member comprises: an upper blade portion operative to form a seed collection slot in the ground; and a lower blade portion laterally offset from the upper blade portion and operative to form a deep rooting slot in the ground that is offset laterally from the seed collection slot.

Abstract: A method for providing a secure computing environment creates an isolated computing environment using supervisory programs that are provided with a public access key of a public-private access key pair and not the private key of the public-private access key pair such that access to the computing environment is unavailable to the supervisory programs to thereby prevent the supervisory programs from affecting results of computations executed in the computing environment. An isolated computing environment is a computing environment in which only a specified maximum number of application processes and specified system processes implementing the computing environment are able to operate. A baseline digest of the isolated computing environment is caused to be generated and stored in a location so that the baseline digest is validated by or available to at least one third party to thereby establish a trusted and isolated computing environment.

Abstract: Seed sowing apparatus comprising: a frame defining a leading part supporting a soil opening stage and a trailing part supporting a soil closing stage trailing the soil opening stage, wherein the soil opening stage comprises a plurality of laterally spaced seeding units, each seeding unit comprising a soil opening member associated with a respective seed delivery outlet connected to a seed source, wherein each seeding unit is configured to form a respective seeded trench in the ground when the apparatus is in use driven through soil in a forward direction of travel; wherein the soil closing stage comprises a plurality of laterally spaced soil deflection members each associated with a respective one of the seeding units, each soil deflection member being spaced laterally from the soil opening member of its respective seeding unit and configured to deflect soil toward the seeded trench formed by the seeding unit.

Abstract: The present disclosure describes a gummy dosage form including: an amino acid in an amount of about 20% by weight or greater; a hydrophilic bulking agent; and a hydrophilic long-chain polymer, wherein at least a portion of the hydrophilic long-chain polymer comprises low methoxyl pectin. The gummy dosage forms can further include additives such as flavorants, fiber, and pH-adjusters. The disclosure further comprises methods for preparing such gummy dosage forms, wherein a hydrophilic bulking agent, a hydrophilic long-chain polymer, and water are combined to give a mixture and heated to give a hydrocolloid system in the form of a slurry; mixing an amino acid with the slurry; and setting the resulting mixture to give the gummy dosage form.

Abstract: In devices that determine levels of substance use, a substance level in a test sample provided to the testing device by a test subject is determined. A sequence of images are captured to include a portion of the face of the test subject providing the test sample and a display of the testing device. A value indicative of the substance level detected within the test sample is determined. A validity indicator indicating validity of the value indicative of the substance level is determined. A current location is determined. The value indicative of the substance level, the validity indicator, and the current location are sent to a remote server.

Abstract: A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hydrophobicity modifying agent, a pH modifying agent and a buffer. A method of treating a patient having pulmonary arterial hypertension includes providing a patient a dry powder inhaler, providing the patient at least one capsule for use in the dry powder inhaler, the capsule including at least 25 micrograms of treprostinil.

Abstract: Described are shoes for ball sports including an upper having an outer surface. An actuator is configured to change at least one surface property of a portion of the outer surface of the upper, and a sensor is configured to be sensitive to movements of the shoe. A processing unit is connected to the actuator and the sensor and configured to process sensor data retrieved from the sensor and to cause the actuator to change the at least one surface property of the portion of the outer surface of the upper if a predetermined event is detected in the sensor data.

Abstract: In accordance a method for storing a dataset, the dataset may be split into fragments that are distributed among different nodes of a network for storage. The fragments may then be retrieved as and when needed and re-assembled. The method allows multiple different fragments to be stored and re-assembled on demand. The dataset is initially stored in a user computing device in communication with a data storage system and a custodial entity. The fragments are stored so that no single computing entity in the storage system or the custodian ever contains or gains knowledge of all the fragments. Additionally, the user computing device that was initially in possession of the dataset and which caused the fragments to be stored in the storage system may be replaced with different user computing devices without losing the capability of storing and re-assembling the user data on demand by the replacement user computing device.

Abstract: A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hydrophobicity modifying agent, a pH modifying agent and a buffer. A method of treating a patient having pulmonary arterial hypertension includes providing a patient a dry powder inhaler, providing the patient at least one capsule for use in the dry powder inhaler, the capsule including at least 25 micrograms of treprostinil.