Abstract: The present invention relates to a cell comprising a chimeric costimulatory antigen receptor (CoStAR) useful in adoptive cell therapy (ACT). The CoStAR can act as a modulator of cellular activity enhancing responses to defined antigens. The present invention also provides CoStAR proteins, nucleic acids encoding the CoStAR and therapeutic uses thereof.

Abstract: A satellite system may have a constellation of communications satellites that provides services to users with electronic devices such as portable electronic devices and home and office equipment. A network operations center may use gateways to communicate with the satellite constellation. The satellite constellation may include sets of satellites with different orbits such as circular orbits with different inclinations, sets of satellites with elliptic orbits, sets of satellites with circular orbits of different altitudes including low earth orbits, medium earth orbits, and/or geosynchronous orbits, and/or sets of satellites with other orbits. The satellite orbits of the satellites in the satellite constellation may be selected to provide coverage to desired user population concentrations at different locations on the earth without using an excessive number of satellites.

Abstract: A screening system for solid removal includes a housing and a screen positioned within the housing. A flow inlet is operatively connected to an interior chamber defined by the screen. A sump is downstream from the flow inlet for capturing solids that do not pass through the screen. A flow outlet is downstream from the screen in fluid communication with the flow inlet. A moveable cleaning assembly may be positioned either within a perimeter of the screen, around the perimeter of the screen or both. The moveable cleaning assembly is moveable with respect to the screen.

Abstract: A satellite system may have a constellation of communications satellites that provides services to users with electronic devices such as portable electronic devices and home and office equipment. A network operations center may use gateways to communicate with the satellite constellation. The satellite constellation may include sets of satellites with different orbits such as circular orbits with different inclinations, sets of satellites with elliptic orbits, sets of satellites with circular orbits of different altitudes including low earth orbits, medium earth orbits, and/or geosynchronous orbits, and/or sets of satellites with other orbits. The satellite orbits of the satellites in the satellite constellation may be selected to provide coverage to desired user population concentrations at different locations on the earth without using an excessive number of satellites.

Abstract: A satellite system may have a constellation of communications satellites that provides services to users with electronic devices such as portable electronic devices and home/office equipment. A network operations center may use gateways to communicate with the satellite constellation. The satellite constellation may include sets of satellites with different orbits such as circular orbits with different inclinations, sets of satellites with elliptic orbits, sets of satellites with circular orbits of different altitudes including low earth orbits, medium earth orbits, and/or geosynchronous orbits, sets of satellites with sun synchronous orbits, and/or sets of satellites with other orbits. The orbits of the satellites in the constellation may be selected to provide coverage to desired user population concentrations at different locations on the Earth, while reducing the amount of capacity that goes unused (e.g., is idle) at one or more times of day.

Abstract: A synthetic hydrogel is described, including hydrated mucin glycoproteins cross-linked with multi-arm thiol functional cross-linker, which can be prepared to model viscoelastic and micro-rheological properties of natural mucus. Such synthetic hydrogel can be prepared from a wide variety of mucin raw materials. Also described is a method of microrheologically characterizing mucus, by dispersing in the mucus muco-inert particles (MIP), irradiating the mucus containing MIP with polarized light, and measuring fluorescence polarization (FP) resulting from rotational diffusion of the MIP in the mucus in response to such irradiating, as a microrheological characteristic of the mucus. This method can be carried out using a plate reader equipped with a spectrofluorometer and polarized filter set, and therefore can be readily carried out in clinical settings without the necessity of specialized microrheological equipment.

Abstract: A satellite system may have a constellation of communications satellites in orbits such as highly inclined eccentric geosynchronous orbits and low earth orbits. To place satellites in inclined eccentric geosynchronous orbits, a series of launch vehicles may be launched. Each launch vehicle may be used to place a set of satellites, such as a set of three satellites, into a common orbital plane with distinct longitude of ascending node values. To place satellites in low earth orbits, a series of launch vehicles may be launched, each of which releases satellites in sequence from a stack of satellites into a common orbital plane. After desired separations have been produced between the released satellites, circularization procedures may be performed using the propulsion systems of the satellites to place the satellites into final orbit.

Abstract: A satellite system may have a constellation of communications satellites that provides services to users with electronic devices such as portable electronic devices and home/office equipment. A network operations center may use gateways to communicate with the satellite constellation. The satellite constellation may include sets of satellites with different orbits such as circular orbits with different inclinations, sets of satellites with elliptic orbits, sets of satellites with circular orbits of different altitudes including low earth orbits, medium earth orbits, and/or geosynchronous orbits, sets of satellites with sun synchronous orbits, and/or sets of satellites with other orbits. The orbits of the satellites in the constellation may be selected to provide coverage to desired user population concentrations at different locations on the Earth, while reducing the amount of capacity that goes unused (e.g., is idle) at one or more times of day.

Abstract: A satellite system may have a constellation of communications satellites that provides services to users with electronic devices such as portable electronic devices and home and office equipment. A network operations center may use gateways to communicate with the satellite constellation. The satellite constellation may include sets of satellites with different orbits such as circular orbits with different inclinations, sets of satellites with elliptic orbits, sets of satellites with circular orbits of different altitudes including low earth orbits, medium earth orbits, and/or geosynchronous orbits, and/or sets of satellites with other orbits. The satellite orbits of the satellites in the satellite constellation may be selected to provide coverage to desired user population concentrations at different locations on the earth without using an excessive number of satellites.

Abstract: A dewatering system for removing solids from an influent includes a filtration assembly and a feed pipe upstream thereof. The dewatering system includes a solids receptacle downstream of the filtration assembly, and an effluent collector adjacent to the filtration assembly and in fluid communication with the filtration assembly. The dewatering system includes a sensor to sense a characteristic of an influent, an effluent and/or a solid. A control system is operatively connected to the sensor to receive a sensor signal therefrom and to generate an adjustment signal based on the sensor signal to improve the efficiency of the dewatering system.

Abstract: A satellite system may have a constellation of communications satellites that provides services to users with electronic devices such as portable electronic devices and home and office equipment. A network operations center may use gateways to communicate with the satellite constellation. The satellite constellation may include sets of satellites with different orbits such as circular orbits with different inclinations, sets of satellites with elliptic orbits, sets of satellites with circular orbits of different altitudes including low earth orbits, medium earth orbits, and/or geosynchronous orbits, and/or sets of satellites with other orbits. The satellite orbits of the satellites in the satellite constellation may be selected to provide coverage to desired user population concentrations at different locations on the earth without using an excessive number of satellites.

Abstract: A satellite system may have a constellation of communications satellites that provides services to users with electronic devices such as portable electronic devices and home and office equipment. A network operations center may use gateways to communicate with the satellite constellation. The satellite constellation may include sets of satellites with different orbits such as circular orbits with different inclinations, sets of satellites with elliptic orbits, sets of satellites with circular orbits of different altitudes including low earth orbits, medium earth orbits, and/or geosynchronous orbits, and/or sets of satellites with other orbits. The satellite orbits of the satellites in the satellite constellation may be selected to provide coverage to desired user population concentrations at different locations on the earth without using an excessive number of satellites.

Abstract: A satellite system may have a constellation of communications satellites that provides services to users with electronic devices such as portable electronic devices and home and office equipment. A network operations center may use gateways to communicate with the satellite constellation. The satellite constellation may include sets of satellites with different orbits such as circular orbits with different inclinations, sets of satellites with elliptic orbits, sets of satellites with circular orbits of different altitudes including low earth orbits, medium earth orbits, and/or geosynchronous orbits, and/or sets of satellites with other orbits. The satellite orbits of the satellites in the satellite constellation may be selected to provide coverage to desired user population concentrations at different locations on the earth without using an excessive number of satellites.

Abstract: A dewatering system for removing solids from an influent includes a filtration assembly and a feed pipe upstream thereof. The dewatering system includes a solids receptacle downstream of the filtration assembly, and an effluent collector adjacent to the filtration assembly and in fluid communication with the filtration assembly. The dewatering system includes a sensor to sense a characteristic of an influent, an effluent and/or a solid. A control system is operatively connected to the sensor to receive a sensor signal therefrom and to generate an adjustment signal based on the sensor signal to improve the efficiency of the dewatering system.

Abstract: A satellite system may have a constellation of communications satellites that provides services to users with electronic devices such as portable electronic devices and home and office equipment. A network operations center may use gateways to communicate with the satellite constellation. The satellite constellation may include sets of satellites with different orbits such as circular orbits with different inclinations, sets of satellites with elliptic orbits, sets of satellites with circular orbits of different altitudes including low earth orbits, medium earth orbits, and/or geosynchronous orbits, and/or sets of satellites with other orbits. The satellite orbits of the satellites in the satellite constellation may be selected to provide coverage to desired user population concentrations at different locations on the earth without using an excessive number of satellites.

Abstract: A satellite system may have a constellation of communications satellites that provides services to users with electronic devices such as portable electronic devices and home/office equipment. A network operations center may use gateways to communicate with the satellite constellation. The satellite constellation may include sets of satellites with different orbits such as circular orbits with different inclinations, sets of satellites with elliptic orbits, sets of satellites with circular orbits of different altitudes including low earth orbits, medium earth orbits, and/or geosynchronous orbits, sets of satellites with sun synchronous orbits, and/or sets of satellites with other orbits. The orbits of the satellites in the constellation may be selected to provide coverage to desired user population concentrations at different locations on the Earth, while reducing the amount of capacity that goes unused (e.g., is idle) at one or more times of day.

Abstract: Apparatus and methods for determining orbital parameters for spacecraft are provided. A computing device can receive a first plurality of orbital parameters defining a first orbit by a first spacecraft of a particular object. The first orbit can have a corresponding first ground track over the particular object. The computing device can receive a following time for a second spacecraft. The computing device can determine a second plurality of orbital parameters for a second orbit by the second spacecraft of the particular object based on the first plurality of orbital parameters and the following time. The second orbit can have a corresponding second ground track over the particular object that follows the first ground track. The computing device can generate an output that includes the second plurality of orbital parameters.

Abstract: Apparatus and methods for determining orbital parameters for spacecraft are provided. A computing device can receive a first plurality of orbital parameters defining a first orbit by a first spacecraft of a particular object. The first orbit can have a corresponding first ground track over the particular object. The computing device can receive a following time for a second spacecraft. The computing device can determine a second plurality of orbital parameters for a second orbit by the second spacecraft of the particular object based on the first plurality of orbital parameters and the following time. The second orbit can have a corresponding second ground track over the particular object that follows the first ground track. The computing device can generate an output that includes the second plurality of orbital parameters.

Abstract: Disclosed is a portable and compact hybrid power unit for ready to use, plug-in power for nearly any environment. Open Energy System (OES) is self-contained in a durable shell that can be deployed almost anywhere in the world. The OES transforms from a rugged box into an energy generating unit with all equipment assembled and ready to generate power. Pre-assembled solar modules can slide out from the opening sides of the unit along a rolling channel, lock into place and open into a ready-to-generate solar electric array. In addition, the OES is mobile and transportable. It can hitch to a vehicle, be dropped in by helicopter, shipped in or used as a permanent unit. Further, the OES unit is designed to fit 5 to a standard shipping container and can be deployed using various shipping methods.

Abstract: Disclosed is a portable and compact hybrid power unit for ready to use, plug-in power for nearly any environment. Open Energy System (OES) is self-contained in a durable shell that can be deployed almost anywhere in the world. The OES transforms from a rugged box into an energy generating unit with all equipment assembled and ready to generate power. Pre-assembled solar modules can slide out from the opening sides of the unit along a rolling channel, lock into place and open into a ready-to-generate solar electric array. In addition, the OES is mobile and transportable. It can hitch to a vehicle, be dropped in by helicopter, shipped in or used as a permanent unit. Further, the OES unit is designed to fit 5 to a standard shipping container and can be deployed using various shipping methods. From the military fighting around the world in rural and hostile areas to reaching disaster affected areas that are in need of crucial power, OES reaches those in need of clean electric power.