Abstract: A line pulling system having a chassis, a reel carrier assembly, an electric power source, and an electric jack assembly. The electric jack assembly can include a housing, a leg configured to extend and retract axially from the housing, an electric motor, a current sensor configured to detect a current supplied to the electric motor, and a controller. The controller can receive current data and, if the current is less than a threshold current, supply a first voltage to the electric motor to cause the electric motor to extend or retract the leg at a first speed. If the current is greater than or equal to the threshold current, the controller can supply a second voltage to the electric motor. The second voltage can cause the electric motor to extend or retract the leg at a second speed that is less than the first speed.

Abstract: A lottery ticket dispensing unit includes at least one ticket compartment and a separation module that has a drive roller and an opposed idler roller. A motor is geared to the drive roller and is switchable between a convey mode wherein the drive roller engages and conveys a leading ticket to a separation position and a brake mode wherein the motor provides a reverse retarding force to the drive roller to brake the drive roller against an attempted reeling of the lottery tickets. from the dispensing unit. A controller switches the motor between the convey and brakes modes such that in the brake mode, power to the motor is interrupted and windings in the motor are short-circuited.

Abstract: Materials and methods for preparing nucleic acid libraries for next-generation sequencing are described herein. A variety of approaches are described relating to the use of unique molecular identifiers with transposon-based technology in the preparation of sequencing libraries. Also described herein are sequencing materials and methods for identifying and correcting amplification and sequencing errors.

Abstract: The present disclosure relates to a synthetic Túngara frog foam composition. The synthetic Túngara frog foam composition comprises six synthetically synthesized ranaspumin proteins (RSN-1 to RSN-6) wherein only the active segments of the RSN proteins are synthesized and six synthetically synthesized polysaccharides comprising four tetrasaccharides, a heptasaccharide and a nonasaccharide. Multiple novel applications of the foam are described.

Abstract: A system for providing impact absorption on an interior surface of an aircraft performing parabolic flight maneuvers including: (1) a liner layer having a first side and an opposing second side; (2) a first compression deflection padding layer having a first side, adhered to the second side of the liner layer, and an opposing second side; (3) a second compression deflection padding layer having a first side, adhered to the second side of the first compression deflection padding layer, and an opposing second side; and (4) a flooring layer having a first side, adhered to the second side of the second compression deflection padding layer, and an opposing second side.

Abstract: A hydraulic system for use during reduced gravity flight including: (1) a reservoir; (2) a hydraulic device; (3) a supply line providing fluid communication between the reservoir and the hydraulic device; (4) a return line providing fluid communication between the hydraulic device and the reservoir; (5) a supply valve located on the supply line between the reservoir and the hydraulic device and selectively configurable in an open or closed position; and (6) a return valve located on the return line between the reservoir and the hydraulic device and selectively configurable in an open or closed position; and (7) wherein the supply valve is adapted to prevent fluid communication between the reservoir and the hydraulic device when in the supply valve closed position; and (8) wherein the return valve is adapted to prevent fluid communication between the reservoir and the hydraulic device when in the return valve closed position.

Abstract: A method of site-specific modification of an endogenous target DNA of a eukaryotic cell is provided. The method includes contacting the endogenous target DNA having an intended modification site with (i) a gene editing system configured to introduce a double strand break in the endogenous target DNA at or near the intended modification site, and (ii) a donor DNA repair template comprising a plurality of tandem repeat sequences. In the method, each of the plurality of tandem repeat sequences comprises an exogenous donor DNA sequence flanked by a donor 5? flanking sequence and a donor 3? flanking sequence. The donor 5? flanking sequence and the donor 3? flanking sequence are homologous to a continuous DNA sequence on either side of the intended modification site in the endogenous target DNA.

Abstract: In certain aspects, the disclosure provides soluble heteromeric polypeptide complexes comprising an extracellular domain of an ALK7 receptor and an extracellular domain of ActRIIB In certain aspects, these ALK7:ActRIIB heteromultimers are can be used to improve metabolic parameters in a patient in need thereof. In certain aspects, these ALK7:ActRIIB heteromultimers are can be used to treat or prevent one or more kidney-associated disease or condition in a patient in need thereof.

Abstract: A non-destructive testing (NDT) system can provide a tree model of an inspection on a display of an NDT device and on a web page configured in a web browser on a computing device coupled to the NDT device. Inspection data acquired using the NDT device can be provided in real-time as the inspection data is associated with a node configured in the tree model. The NDT system can generate an inspection tree model based on an inspection template including a template tree model. Defect properties, inspection instructions, and/or image transforms can be applied to nodes of the template tree model such that the generated inspection tree model includes the applied defect properties, inspection instructions, and/or image transforms, which can then be applied to the inspection data acquired at the inspection point location corresponding to each node.

Abstract: The present disclosure relates to agonists of interferon alpha and beta receptor subunit 2 (IFNAR2) for use in the treatment or prevention of viral disease, particularly COVID-19. In particular embodiments, COVID-19 is associated with pneumonia or acute respiratory distress syndrome (ARDS). In other aspects, the subject being treated is undergoing extra-corporeal membrane oxygenation, mechanical ventilation, non-invasive ventilation, receiving oxygen therapy or receiving antiviral or steroid treatment.

Abstract: The present invention is directed to a method of treating skin and scalp comprising applying on the scalp or skin a composition comprising a scalp care active selected from the group consisting of 2-Pyridinol-N-oxide, a pyrithione or a polyvalent metal salt of pyrithione, one or more iron chelator having an A log P value of greater than or equal to 0.4 and mixtures therein; exposing the scalp and skin to electromagnetic radiation having wavelength from about 350 nm to about 500 nm and power from about about 0.1 mWatts/cm2 to about 1000 mWatts/cm2 and for a time period from about 2 seconds to about 5 minutes; wherein the antimicrobial treatment results in reduction of fungal growth as measured by the Fungal Growth Sensitivity Test of at least 50% compared to the dark sample.

Abstract: A support base for a child safety seat includes a shell, a belt clamp and a latching mechanism. The shell is adapted to receive a child seat thereon, and has a belt anchoring region including a first surface and a second surface. The belt clamp is pivotally connected with the shell, and is operable to clamp a first belt portion and a second belt portion respectively adjacent to the first surface and the second surface. The latching mechanism is operable to lock the belt clamp in a clamping state.

Abstract: Presented herein are systems and methods for prediction, and especially automated prediction, of subject response to cancer therapies. Also presented herein are methods for selection of cancer therapies based upon predicted subject response and/or technologies for administering cancer therapies to appropriate subjects.

Abstract: Examples disclosed herein relate to a gaming device including a memory, a processor, a display, a plurality of display areas located on the display, and a plurality of external lights located at an outer area of a front surface of the electronic gaming device. The plurality of external lights forming au-shape with a left side, a right side, and a bottom where each of the left side, the right side, and the bottom includes a first light column, a second light column, and a third light column. The gaming device including a processor that initiates a base game via the plurality of display areas located on the display.

Abstract: Described herein are methods and compositions for reducing or preventing arrhythmias associated with or caused by transplantation of cardiomyocytes to cardiac tissue. In particular embodiments, the pre-treatment of in vitro-differentiated cardiomyocytes with amiodarone before administration to cardiac tissue for engraftment reduces or prevents engraftment arrhythmias, and/or reduces the need for adjunctive anti-arrhythmia drugs after cell administration.

Abstract: An example device comprises: a head-mounted display; a housing for the head-mounted display, the housing including an external surface; sensors to monitor a wearer of the head-mounted display; a visual indicator at the external surface; and a controller. The controller is generally to: control subsets of the sensors to be on or off based on respective permissions for usage of subsets of the sensors; and control the visual indicator to indicate respective status of the subsets of the sensors.

Abstract: Embodiments of the present disclosure describe fabric covers, such as those used for air conditioning units, having a first air permeable panel for covering a horizontal top panel of an air conditioner unit; a second air permeable panel extending downward from the first air permeable panel for covering vertical side panels of the air conditioner unit; and an adjustable fastener provided in a bottom portion of the second air permeable panel for securing the cover to a base of the air conditioner unit.

Abstract: Apparatus, systems, and processes control an electric motor to drive a hoop onto a wooden barrel, among other purposes. A controller may be connected to the electric motor and configured to receive user input data and generate one or more control signals for the electric motor that correspond to a torque generation of the electric motor and/or a rotation speed of the electric motor. A barrel hoop driver may comprise the controller and electric motor, where the electric motor drives a press member for driving hoops onto wooden barrels.

Abstract: A system and method are disclosed for modeling a non-relational database as a normalized relational database. In one embodiment, the system identifies a column having a first type in a column-oriented, non-relational database; determines whether the column-oriented, non-relational database includes at least one column having a second type and identifies the one or more columns having the second type; virtually divides the column-oriented, non-relational database based on column type; and generates a normalized, relational model based on the virtual division of the column-oriented, non-relational database, the normalized, relational model including catalog information representing a parent table including the column having the first type and, when the column-oriented, non-relational database includes at least one column having the second type, catalogue information representing a child table, the parent table and child table both represented as relational tables.

Abstract: This application describes methods of preparing an immobilized library of tagged RNA fragments. Also described herein are a number of methods of preparing DNA and RNA sequencing libraries from a single sample. These methods can include library preparation from single cells.