Abstract: Provided is a method of granting access, including compiling a training profile of each of two or more persons, wherein the training profile includes one or more oculomotor features exhibited during one or more tasks, associating a training profile of one of the two or more persons with a permission, detecting a testing profile of one of the two or more persons, wherein the testing profile includes one or more of the one or more oculomotor features exhibited by during one or more of the one or more tasks, identifying a target profile, granting access if and only if the target profile is associated with the permission, wherein the one or more tasks are selected from fixation, saccade speed, saccade accuracy, visually-guided saccades, anti-saccades, memory-guided saccades, free viewing, pursuit.

Abstract: An inductive position sensor device for detecting the position of a coupling element which can be arranged on a movable actuator element of an electric machine is disclosed. The inductive position sensor device includes (i) at least one transmitter coil for generating electromagnetic waves, (ii) at least one receiver coil for detecting the electromagnetic waves which are generated by the transmitter coil and are influenced by the actuator element, and (iii) a computing unit which is designed to actuate the transmitter coil and evaluate the electromagnetic waves detected by the receiver coil in order to determine the position. The coils are arranged on a front face of a common printed circuit board, and the computing unit is arranged on a rear face of the common printed circuit board. The coils are electrically connected to the computing unit by connection lines which extend along the printed circuit board and through the printed circuit board. The connection lines run substantially parallel to one another.

Abstract: The disclosure describes articles having coating systems configured to inhibit or prevent crystallization of TGO at the operating temperature of the article. An article includes a substrate defining a surface; a bond coat on the surface of the substrate; a coating layer that includes a boron dopant configured to inhibit crystallization of amorphous silicon dioxide thermally grown oxide on the bond coat at an operating temperature of the article. By inhibiting or preventing TGO crystallization, the described coating systems may increase a useable life of the component.

Abstract: Methods and constructs for engineering circular RNA are disclosed. In some embodiments, the methods and constructs comprise a vector for making circular RNA, the vector comprising the following elements operably connected to each other and arranged in the following sequence: a.) a 5? homology arm, b.) a 3? group I intron fragment containing a 3? splice site dinucleotide, c.) optionally, a 5? spacer sequence, d.) a protein coding or noncoding region, e.) optionally, a 3? spacer sequence, f) a 5? Group I intron fragment containing a 5? splice site dinucleotide, and g.) a 3? homology arm, the vector allowing production of a circular RNA that is translatable or biologically active inside eukaryotic cells. Methods for purifying the circular RNA produced by the vector and the use of nucleoside modifications in circular RNA produced by the vector are also disclosed.

Abstract: The disclosure concerns snake-derived peptides and the useful application of such peptides to inhibit bacterial, fungal, viral and parasitic infections. The disclosed peptides are also useful for the treatment of an inflammatory condition or cancers.

Abstract: An auxiliary measurement display device, comprises a communication interface configured to receive incoming measurement-related data and transmit outgoing measurement-related data, a display configured to display measurement information, a user interface configured to receive user input, and a controller coupled to the communication interface and the display and the user interface, wherein the controller is configured to control the display to display the measurement information based on the incoming measurement-related data, and wherein the controller is configured to generate the outgoing measurement-related data based on the received user input and transmit the outgoing measurement-related data via the communication interface. In addition, the present disclosure provides a respective computer program product, a measurement server, a respective measurement system and a respective method.

Abstract: Methods, systems, and devices for emotional well-being correlation are described. A system may receive physiological data associated with a user from a wearable device worn by the user, environmental data including characteristics of an environment of the user, and feedback data from the user indicating a physical state or a psychological state of the user when experiencing the at least one environmental characteristic. The system may additionally determine a set of relationships between the received environmental data and the received feedback data, the received physiological data, or both. Additionally, the system may generate a message for the user based on the set of relationships and display the message to the user via a graphical user interface (GUI) of a user device. The message may include instructions for regulating the physical state of the user, the psychological state of the user, or both, when experiencing the characteristics of the environment.

Abstract: A method and system provide for on-board localization in a unmanned aerial system (UAS). A map image if generated (using previously acquired images) of an area that the UAS is overflying. The map image is then processed by orthorectifying, referencing the map image in a global reference frame, and generating an abstract map by detecting features and locating the features in the global reference frame. The UAS is then localized by acquiring camera images during flight, selecting a subset of the camera images as localization images, detecting on-board image features (in the localization images), mapping features from the detected on-board image features to the abstract map, deleting outliers to determine an estimated 3D pose, and refining the 3D pose. The localized UAS then used to autonomously navigate the UAS.

Abstract: Systems, apparatuses, and methods are described for a stairlift overspeed safety system are disclosed. The overspeed safety system may include a centripetal cam assembly, a trigger assembly, and a jammer assembly. The centripetal cam assembly may include a spring-loaded plate and a plurality of centripetal cams connected to the spring-loaded plate, configured to move to an extended position when the rail speed exceeds the speed threshold. The trigger assembly may include a trigger plate configured to be pushed by at least one of the centripetal cams when moved to the extended position. Pushing the trigger plate may cause a switch to open to shut off power to the motorized stairlift. The jammer assembly may include a jammer configured to wedge between teeth of a rack and pinion of the motorized stairlift to initiate a deceleration to stop movement of the motorized stairlift.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, apparatuses, and processes that dynamically and securely augment a programmatically established communications session, such as a chatbot session, to include one or more additional responsive applications. For example, an apparatus may receive messaging data during a first communication session programmatically established between a device and a first executed application program, and may determine that an additional apparatus is configured to perform operations consistent with the messaging data. The apparatus may transmit a digital token and at least a portion of the messaging data to an additional apparatus. A second application executed by the additional apparatus may validate the digital token and based on the portion of the messaging data, establish a second communication session between the device and the executed first and second application programs.

Abstract: Circular RNA and transfer vehicles, along with related compositions and methods are described herein. In some embodiments, the inventive circular RNA comprises group I intron fragments, spacers, an IRES, duplex forming regions, and an expression sequence. In some embodiments, the expression sequence encodes a chimeric antigen receptor (CAR). In some embodiments, circular RNA of the invention has improved expression, functional stability, immunogenicity, ease of manufacturing, and/or half-life when compared to linear RNA. In some embodiments, inventive methods and constructs result in improved circularization efficiency, splicing efficiency, and/or purity when compared to existing RNA circularization approaches.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, apparatuses, and processes that dynamically and securely augment participants in programmatically established chatbot sessions. For example, an apparatus may obtain messaging data generated during a first communications session involving a first device and based on the messaging data, detecting an occurrence of an event that triggers an establishment of a second communications session involving the first device and a second device. The apparatus may generate and transmit, to the second device, notification data causing the second device to validate one or more authentication credentials, and may receive confirmation data indicative of the one or more validated authentication credentials from the second device. Based on the confirmation data, the apparatus may perform operations that establish the second communications session in accordance with at least a portion of the messaging data.

Abstract: Circular RNA and transfer vehicles, along with related compositions and methods are described herein. In some embodiments, the inventive circular RNA comprises group I intron fragments, spacers, an IRES, duplex forming regions, and an expression sequence. In some embodiments, the expression sequence encodes a chimeric antigen receptor (CAR). In some embodiments, circular RNA of the invention has improved expression, functional stability, immunogenicity, ease of manufacturing, and/or half-life when compared to linear RNA. In some embodiments, inventive methods and constructs result in improved circularization efficiency, splicing efficiency, and/or purity when compared to existing RNA circularization approaches.

Abstract: A system and method for ingesting, normalizing and analyzing multiple disparate datasets surrounding live sports events combined with real-time viewing content recognition and understanding on a user device to enable digital services to recommend real-time, personalized interactive offers such as sports bet offers to the device that are synchronized to live events being visual or audibly projected proximate the user device despite inherent latency between the user device and the projected live event.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, apparatuses, and processes that dynamically configure and populate a digital interface based on sequential elements of message data exchanged during a chatbot session established programmatically between an apparatus and a device. For example, the apparatus may generate first messaging data that includes a candidate input value for an interface element of a digital interface, and transmit the first messaging data to the device during the programmatically established chatbot session. The apparatus may also receive, from the device during the programmatically established chatbot session, second messaging data that includes a confirmation of the candidate input value. Based on the second messaging data, the apparatus may generate populated interface data that associates the interface element with the confirmed candidate input value, and store the populated interface data within a memory.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, apparatuses, and processes that dynamically and securely augment participants in programmatically established chatbot sessions. For example, an apparatus may obtain messaging data generated during a first communications session involving a first device and based on the messaging data, detecting an occurrence of an event that triggers an establishment of a second communications session involving the first device and a second device. The apparatus may generate and transmit, to the second device, notification data causing the second device to validate one or more authentication credentials, and may receive confirmation data indicative of the one or more validated authentication credentials from the second device. Based on the confirmation data, the apparatus may perform operations that establish the second communications session in accordance with at least a portion of the messaging data.

Abstract: Disclosed herein are circular RNAs and transfer vehicles, along with related compositions and methods of treatment. The circular RNAs can comprise group I intron fragments, spacers, an IRES, duplex forming regions, and/or an expression sequence, thereby having the features of improved expression, functional stability, low immunogenicity, ease of manufacturing, and/or extended half-life compared to linear RNA. Pharmaceutical compositions comprising such circular RNAs and transfer vehicles are particularly suitable for efficient protein expression in immune cells in vivo. Also disclosed are precursor RNAs and materials useful in producing the precursor or circular RNAs, which have improved circularization efficiency and/or are compatible with effective circular RNA purification methods.

Abstract: A threaded fastener composed of separate upper and lower portions with a small axial freedom of movement relative to one another. After being threaded into a blind hole together, the portions are moved relative to one another and locked in place, creating a distribution of stresses which resists backing-out of the fastener without the various drawbacks which limit prior art solutions to this and similar threaded fastener applications.

Abstract: Examples of ensemble knowledge transfer in collaborative learning include: receiving, at a primary node, from a plurality of remote nodes, a plurality of trained proxy machine learning (ML) models, wherein each proxy ML model is received from a different one of the plurality of remote nodes, and wherein each of the plurality of remote nodes is remote across a network from the primary node; training a primary ML model using the plurality of proxy ML models, wherein training the primary ML model comprises: for each of a plurality of training cases of a primary training dataset, weighting results from each of the proxy ML models based on at least a confidence of the respective proxy ML model regarding the training case.

Abstract: The present invention provides a compound of formula (1) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.