Abstract: Methods and constructs for engineering circular RNA are disclosed. In some embodiments, the methods and constructs comprise a vector for making circular RNA, the vector comprising the following elements operably connected to each other and arranged in the following sequence: a.) a 5? homology arm, b.) a 3? group I intron fragment containing a 3? splice site dinucleotide, c.) optionally, a 5? spacer sequence, d.) a protein coding or noncoding region, e.) optionally, a 3? spacer sequence, f) a 5? Group I intron fragment containing a 5? splice site dinucleotide, and g.) a 3? homology arm, the vector allowing production of a circular RNA that is translatable or biologically active inside eukaryotic cells. Methods for purifying the circular RNA produced by the vector and the use of nucleoside modifications in circular RNA produced by the vector are also disclosed.

Abstract: The present disclosure relates to systems and methods for an interactive, intelligent hub built around the completion of a task. This hub brings together resources, information, suggested steps, and other automated assistance to facilitate the completion of the task. AI-based assistance may indicate which steps can be completed by automated processes, and dispatch those processes, or suggest resources to assist in the completion of other steps. The hub displays the current status of the task, and lives until the completion of the task, or abandonment by the user.

Abstract: An optical communication system includes a transmitter and at least one receiver employing a feature of an outdoor environment, or includes a transmitter and a receiver in each of multiple transceivers employing a respective or shared feature of the outdoor environment. The transmitter includes a laser emitting a beam of laser pulses having a wavelength. The transmitter encodes data into the laser pulses in the beam, and transmits the beam of laser pulses through free space of the outdoor environment and then onto a feature of the outdoor environment. Each receiver includes a line filter blocking light not having the wavelength. The receiver decodes data from the light that passes through the line filter and includes a diffusion of the beam from the feature.

Abstract: An engine comprises an air intake arrangement configured to receive air; a heat exchanger arrangement arranged downstream of the air intake arrangement, configured to cool the air, and comprising a plurality of heat exchanger modules; and one or more turbomachinery components configured to receive cooled air from the heat exchanger arrangement. The plurality of heat exchanger modules are arranged to be generally centred on and to be arranged along a longitudinal axis of the engine. At least one of the plurality of heat exchanger modules is arranged to at least partially overlap with at least one other one of the plurality of heat exchanger modules relative to the longitudinal axis of the engine.

Abstract: Respiratory biofeedback-based content selection and playback includes using data obtained using one or more sensors of a mobile device running a software application to produce a respiratory data stream of a user of the software application and select content to output to the user. The respiratory data stream represents various respiratory information of the user and is processed to determine a user state of the user. Certain content is selected based on the user state and based on a defined respiratory objective of a guided session being run using the software application. Initial content previously output to the user during the guided session may then be adjusted by outputting the selected content to the user. A change in the user state resulting from the outputting of the selected content may then be used to determine a progress of the user toward achieving the defined respiratory objective of the guided session.

Abstract: A system and method for remotely monitoring and analyzing devices on a wireless network, such as a ZIGBEE® network, is disclosed. The devices store event logs in a memory device whenever certain events occurs. These event logs are transmitted to a gateway device. The gateway device may operate in standalone mode or in network coprocessor (NCP) mode. The gateway device may then decode the event logs into a human readable output. This human readable output may then be uploaded to a server in the cloud, where further analysis of the human readable output may be performed. This information may then be retrieved by remote devices, such as smart phones. In other modes, the event logs are uploaded to the server in the cloud and the decoding is performed in the cloud.

Abstract: Methods and constructs for engineering circular RNA are disclosed. In some embodiments, the methods and constructs comprise a vector for making circular RNA, the vector comprising the following elements operably connected to each other and arranged in the following sequence: a.) a 5? homology arm, b.) a 3? group I intron fragment containing a 3? splice site dinucleotide, c.) optionally, a 5? spacer sequence, d.) a protein coding or noncoding region, e.) optionally, a 3? spacer sequence, f.) a 5? Group I intron fragment containing a 5? splice site dinucleotide, and g.) a 3? homology arm, the vector allowing production of a circular RNA that is translatable or biologically active inside eukaryotic cells. Methods for purifying the circular RNA produced by the vector and the use of nucleoside modifications in circular RNA produced by the vector are also disclosed.

Abstract: Methods and constructs for engineering circular RNA are disclosed. In some embodiments, the methods and constructs comprise a vector for making circular RNA, the vector comprising the following elements operably connected to each other and arranged in the following sequence: a.) a 5? homology arm, b.) a 3? group I intron fragment containing a 3? splice site dinucleotide, c.) optionally, a 5? spacer sequence, d.) a protein coding or noncoding region, e.) optionally, a 3? spacer sequence, f) a 5? Group I intron fragment containing a 5? splice site dinucleotide, and g.) a 3? homology arm, the vector allowing production of a circular RNA that is translatable or biologically active inside eukaryotic cells. Methods for purifying the circular RNA produced by the vector and the use of nucleoside modifications in circular RNA produced by the vector are also disclosed.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, apparatuses, and processes that dynamically and securely augment a programmatically established communications session, such as a chatbot session, to include one or more additional responsive applications. For example, an apparatus may receive messaging data during a first communication session programmatically established between a device and a first executed application program, and may determine that an additional apparatus is configured to perform operations consistent with the messaging data. The apparatus may transmit a digital token and at least a portion of the messaging data to an additional apparatus. A second application executed by the additional apparatus may validate the digital token and based on the portion of the messaging data, establish a second communication session between the device and the executed first and second application programs.

Abstract: A data management device, communication system and methods for tagging data in a data table and triggering automated action. A data management device receives from a first data provider one or more records of a data table, each record comprising a plurality of fields. The data table is associated with an account having one or more authorized users. The plurality of fields each has a value set by the first data provider. The data manger determines one or more tags for the one or more records in accordance with a plurality of autotagging rules. The data manger appends the one or more records to include one or more tag fields corresponding to the one or more tags for the one or more records. The appended records are stored in a database. One or more automated actions may be triggered based on one or more tag fields of one or more of the plurality of records.

Abstract: Systems, apparatuses, and methods are described for a stairlift overspeed safety system are disclosed. The overspeed safety system may include a centripetal cam assembly, a trigger assembly, and a jammer assembly. The centripetal cam assembly may include a spring-loaded plate and a plurality of centripetal cams connected to the spring-loaded plate, configured to move to an extended position when the rail speed exceeds the speed threshold. The trigger assembly may include a trigger plate configured to be pushed by at least one of the centripetal cams when moved to the extended position. Pushing the trigger plate may cause a switch to open to shut off power to the motorized stairlift. The jammer assembly may include a jammer configured to wedge between teeth of a rack and pinion of the motorized stairlift to initiate a deceleration to stop movement of the motorized stairlift.

Abstract: Methods, systems, and devices for activity classification are described. A system may receive physiological data associated with a user via a wearable device, where the physiological data includes at least motion data. The system may identify an activity segment during which the user is engaged in a physical activity based on the motion data, where the activity segment is associated with activity segment data including at least the physiological data collected during the activity segment. The system may generate activity classification data associated with the activity segment based on the activity segment data, the activity classification data including a set of classified activity types and corresponding confidence values. The system may then cause a graphical user interface (GUI) of a user device to display the activity segment data and at least one classified activity type of the set of classified activity types.

Abstract: Systems, apparatuses, and methods are described for a stairlift overspeed safety system are disclosed. The overspeed safety system may include a centripetal cam assembly, a trigger assembly, and a jammer assembly. The centripetal cam assembly may include a spring-loaded plate and a plurality of centripetal cams connected to the spring-loaded plate, configured to move to an extended position when the rail speed exceeds the speed threshold. The trigger assembly may include a trigger plate configured to be pushed by at least one of the centripetal cams when moved to the extended position. Pushing the trigger plate may cause a switch to open to shut off power to the motorized stairlift. The jammer assembly may include a jammer configured to wedge between teeth of a rack and pinion of the motorized stairlift to initiate a deceleration to stop movement of the motorized stairlift.

Abstract: An enclosure configured to simultaneously accommodate different connectorization applications includes a backplate and a bulkhead bracket and splice retention clips coupled to the backplate. The bulkhead bracket includes openings configured to house adapters for a first connecterized application. The splice retention clips are configured to accommodate one or more of a fusion splice protector and a mechanical splice for a second connecterized application. The bulkhead bracket, with or without an adapter, is configured to be uncoupled from the backplate to allow access to the splice retention clips for insertion or deletion of the fusion splice protector or the mechanical splice. The bulkhead bracket is configured to be recoupled with the backplate and over the splice retention clips.

Abstract: A programmable, deformable incident-energy shaper comprising: a base having top and bottom surfaces with a perforation there-between; a protrusion connected to, and extending outwardly from, a center of the top surface; a deformable layer firmly attached to the base's perimeter and to a tip of the protrusion such that a majority of the deformable layer is suspended in free space between the tip and the perimeter, wherein the deformable layer is configured to flex inwardly or outwardly, and wherein the perforation provides a fluid channel to ambient fluid; and an actuator, operatively coupled to the deformable layer and configured to cause the deformable layer to flex inwardly or outwardly upon command.

Abstract: A system for detecting sound comprising a laser beam transmitter transmitting at least two parallel modulated laser beams through a medium having a measurable index of refraction, a beam termination mechanism configured to terminate the laser beams' transmission through the medium, a guide mechanism used to guide the terminated laser beam to at least one beam combiner, an envelope detector optically coupled to the beam combiner, wherein the envelope detector is configured to receive the terminated laser beam from the beam combiner, creating an angle modulated signal; a processor used to process the angle modulated signal to recover the sound.

Abstract: A system and method for remotely monitoring and analyzing devices on a wireless network, such as a ZIGBEE® network, is disclosed. The devices store event logs in a memory device whenever certain events occurs. These event logs are transmitted to a gateway device. The gateway device may operate in standalone mode or in network coprocessor (NCP) mode. The gateway device may then decode the event logs into a human readable output. This human readable output may then be uploaded to a server in the cloud, where further analysis of the human readable output may be performed. This information may then be retrieved by remote devices, such as smart phones. In other modes, the event logs are uploaded to the server in the cloud and the decoding is performed in the cloud.

Abstract: Systems, methods, and non-transitory computer-readable media can receive render instructions for rendering an animation. The animation comprises a plurality of layers, each layer comprising one or more layer properties, and a first dynamic property to be defined at runtime prior to rendering the animation. The first dynamic property is mapped to a first set of layer properties of the one or more layer properties. A first dynamic property value is received for the first dynamic property. The first set of layer properties are defined based on the first dynamic property value. The animation is rendered on a computing device based on the render instructions and the first dynamic property value.

Abstract: The disclosure concerns snake-derived peptides and the useful application of such peptides to inhibit bacterial, fungal, viral and parasitic infections. The disclosed peptides are also useful for the treatment of an inflammatory condition or cancers.