Abstract: Disclosed herein are arylpyridinone compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structures of Formulas (I)-(IV): wherein the R groups, m, n, and X are as defined in the detailed description. Methods of inhibition of ITK activity in a human or animal subject are also provided.

Abstract: A panel system includes a chassis holding one or more tray arrangements, which are each configured to receive one or more cassettes at two or more bays. The tray arrangements and cassettes cooperate to define a cassette sensor arrangement and a port occupancy sensor arrangement having separate interface points. The cassette sensor arrangement may include electronic memory storing physical layer information about the cassette. All active components of the port occupancy sensor arrangement are disposed on the tray while the electronic memories of the cassette sensor arrangement are stored on the cassettes.

Abstract: An interconnect structure for an integrated circuit includes a plurality of first-type interconnect elements and a second-type of interconnect element which directly contact an underlying first-type interconnect element. The second-type interconnect element extends along a first axis to define a horizontal length and along a second axis to define a vertical height. The second-type interconnect element and the first-type interconnect element define a conductive via comprising a metal material extending continuously along the second axis from a base of the underlying first-type interconnect element and stopping at the upper surface of the second-type interconnect element. The vertical height of the second-type interconnect element is greater than the vertical height of the first-type interconnect elements.

Abstract: A technology is described for a dual path repeater configurable for a split mode and a multiple input multiple output (MIMO) mode. The dual path repeater can comprise first and second server ports and first and second donor ports. Four amplification and filtering paths are communicatively coupled between the ports. Each amplification and filtering path include a software defined filter (SDF). The SDFs are configured to filter the same 3GPP bands to provide MIMO communication or the first SDF and the second SDF are configured to filter different bands to enable the dual path switchable repeater to provide split mode communication on multiple TDD/FDD bands.

Abstract: Nanofiber filter media ribbons are flexible elongate strips of polymeric material having a surface on which is formed an array of nanofibers. Ribbons are formable into woven or non-woven mats. The array of nanofibers can be configured to filter a predetermined contaminant from a fluid stream passing through the mats. Filter ribbons are formable by applying a moldable polymer to a first angular location of a rotating cylindrical roll having an array of nanoholes formed in a circumferential surface thereof so that the polymer covers the surface of the roll and infiltrates the nanoholes; cooling the polymer while rotating the polymer-covered roll to a second angular position; and removing the cooled polymer from the roll as an elongate film having an array of nanofibers formed on a surface thereof by the polymer that infiltrated the nanoholes.

Abstract: A method comprises storing first transaction data for a first transaction producing a first version of a first dataset, second transaction data for a second transaction transforming a first version of the first dataset to a second version of the first dataset, and third transaction data for a third transaction transforming the second version of the first dataset to a third version of the first dataset; storing dependency information indicating a first dependency of the third transaction on the second transaction and a second dependency of the second transaction on the first transaction; receiving a first instruction to revoke a first permission of a first user to access the second version of the first dataset; automatically revoking a certain permission of the first user to access the third version of the first dataset based on the dependency information.

Abstract: A technology is described for a time division duplex (TDD) repeater with circulators. The TDD repeater can comprise a first port, a second port, a first circulator, a second circulator, and first and second amplification paths coupled between the first circulator and first port and the second circulator and second port. The TDD repeater can comprise a software defined filter (SDF) on each of the first and second amplification paths to filter selected symbols of TDD signals on the first and second amplification paths.

Abstract: Systems, methods, and apparatuses disclosed herein can generate vibrations in relation to, for example, synchronous with, audio that is associated with an event being hosted at a venue. These systems, methods, and apparatuses can generate the vibrations at the one or more frequencies over the one or more intervals in time to provide physical sensations to an audience within the venue as the audience is viewing the event. These physical sensations can provide new immersive experiences to the audience as the audience is viewing the event. These systems, methods, and apparatuses can be mechanically coupled, for example, attached, to seats within the venue. The vibrations generated by these systems, methods, and apparatuses can propagate through the seats onto the audience to provide the new immersive experiences to the audience as the audience is viewing the event.

Abstract: The current invention features a rod screw for medical application that can be configured and used to fixate fracture of bones varying in shape and dimension, and treating maladies such as scoliosis, and securing an implanted device, to tissue such as bone. This is achieved by designing a flexible rod screw with a mechanism to lock the configuration in a rigid state. In an embodiment, a bone-fracture fixation device, such as a rod screw, includes a flexible body, a plurality of flexible members, and first and second interfaces. The flexible members are disposed longitudinally within the flexible body, such that the flexible body is rigid when the flexible members are fixed into position. And the first and second interfaces are respectively coupled to the flexible body, each of at least one of the first and second interfaces including a respective at least one hole each configured to receive a respective attachment member configured to engage a bone.

Abstract: A method for controlling a dual fuel engine system includes estimating a total indicated engine load, where the total indicated engine load is based on a sum of a measured engine power and a power loss estimate. The method further includes determining a total fueling amount based on an engine speed and the total indicated engine load, where the total fueling amount includes a gas fueling amount and a diesel fueling amount. The method also includes controlling the dual fuel engine system using the total fueling amount.

Abstract: A technology is described for a terrestrial and non-terrestrial signal repeater system operable to receive, filter, amplify, and transmit terrestrial and non-terrestrial signals. The repeater system includes a donor port, a server port, a first direction amplification and filtering paths and second direction amplification and filtering paths coupled between the ports, and a controller. One or more donor antennas are configured to be coupled to a donor port of the repeater. One of the one or more donor ports can be configured to transmit and receive signals with an orbiting satellite.

Abstract: A method for controlling a dual fuel engine system includes determining a friction power loss amount of an internal combustion engine of the dual fuel engine system, where the friction power loss amount is based on an engine speed of the internal combustion engine and a friction torque estimate. The method also includes determining an accessory power loss amount of a power of the internal combustion engine, where the accessory power loss amount is based on the engine speed and an accessory torque estimate. The method further includes estimating a net engine power amount based on the accessory power loss amount and a brake power amount of the internal combustion engine, estimating an indicated diesel power, and estimating, based on the estimated net engine power, a first indicated engine power and a first gas power.

Abstract: In one example, a centrifugal fan includes a bearing, a shaft rotatably supported by the bearing, fan blades operatively connected to and rotatable with the shaft to take in air axially and to exhaust air radially, and a groove in the shaft extending axially along an outer surface of the shaft through the bearing.

Abstract: A technology is described for a repeater. The repeater can comprise a first antenna port, a second antenna port, one or more first direction amplification and filtering paths, one or more second direction amplification and filtering paths, and a controller. The first antenna port can be configured to be coupled to a first antenna. The second antenna port can be configured to be coupled to a second antenna. The one or more first direction amplification and filtering paths can be coupled between the first antenna port and the second antenna port. The one or more second direction amplification and filtering paths can be coupled between the first antenna port and the second antenna port. The controller can be configured to switch the repeater between a radio frequency (RF) mode or a fiber optic mode.

Abstract: The present invention relates to new pyrrolopyridine compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK1 and JAK3 kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.

Abstract: In various embodiments, crowd sourcing techniques are provided to enable RTT-based positioning of UE. To address issues of discovering which beacons (e.g., Wi-Fi APs, cellular base stations, BLE transmitters, etc.) support measurement of RTT (e.g., according to IEEE 802.11mc, 3GPP Release 16, etc.), beacon RTT capabilities may be crowd-sourced from UE and maintained by a cloud-based location platform in a beacon database (or more specifically, a RTT database portion thereof). To address the issue of determining physical antenna positions, RTT measurements may be crowd-sourced from UE for those beacons that are RTT capable, and used by a trilateration algorithm (e.g., a WLS multilateration algorithm) to determine physical antenna positions, which also may be maintained in the beacon database. Accuracy of the trilateration may be enhanced by obtaining raw GNSS measurements (e.g., psuedoranges) from the UE, and performing a cloud-based RTK GNSS position fix for the UE.

Abstract: A circumcision device and methods for using and manufacturing the same are disclosed. Embodiments of the circumcision device include a connector that permits the circumcision device to be connected by hand to and disconnected by hand from a tissue holding member while the tissue holding member is holding penile tissue. The connector permits the circumcision device to rotate while connected to the tissue holding member. Embodiments include a blade (cutting member) that is bent at an angle that may be oblique, and the blade may include a slot on either side of or across the bend. Further embodiments include at least one gripping member that extends perpendicularly to the axis the device rotates around, while additional embodiments include at least one gripping member that is aligned with the connector to assist in connection and removal of the device from a tissue holding member.

Abstract: A system for distributing wireless networking components in a venue. The system includes panels that define a floor surface. The panels each have a planar configuration with an upper surface opposite a lower surface. The panels include a material that is transparent to radio waves, and the panels define a storage space below the panels and the storage space may be used to store and distribute wireless networking component.

Abstract: In various embodiments, crowd sourcing techniques are provided to enable RTT-based positioning of UE. To address issues of discovering which beacons (e.g., Wi-Fi APs, cellular base stations, BLE transmitters, etc.) support measurement of RTT (e.g., according to IEEE 802.11mc, 3GPP Release 16, etc.), beacon RTT capabilities may be crowd-sourced from UE and maintained by a cloud-based location platform in a beacon database (or more specifically, a RTT database portion thereof). To address the issue of determining physical antenna positions, RTT measurements may be crowd-sourced from UE for those beacons that am RTT capable, and used by a trilateration algorithm (e.g., a WLS multilateration algorithm) to determine physical antenna positions, which also may be maintained in the beacon database. Accuracy of the trilateration may be enhanced by obtaining raw GNSS measurements (e.g., psuedoranges) from the UE, and performing a cloud-based RTK GNSS position fix for the UE.

Abstract: Technology for a repeater is disclosed. The repeater can include a first-direction signal path configured to amplify and filter a signal in a first-direction band using a first bandpass filter. The repeater can include a second-direction signal path configured to amplify and filter a signal in a second-direction band using a second bandpass filter. The second-direction band can be spectrally adjacent to the first-direction band. The first bandpass filter and the second bandpass filter can provide filtering to isolate the first-direction band from the spectrally adjacent second-direction band.