Patents by Inventor Robert B. Garland

Robert B. Garland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intermediates for the synthesis of 4-demethoxydaunorubicin
    Patent number: 4161480
    Abstract: The present invention encompasses novel intermediates having the following structural formulas: ##STR1## wherein X is hydrogen, methoxy, or hydroxy; ##STR2## wherein X is hydrogen, methoxy, or hydroxy; and ##STR3## wherein X is hydrogen, methoxy, or hydroxy. Compounds of the present invention are useful in synthesizing 4-demethoxydaunorubicin, daunorubicin, adriamycin, and carminomycin which are potent antitumor agents.
    Type: Grant
    Filed: June 5, 1978
    Date of Patent: July 17, 1979
    Assignee: G. D. Searle & Co.
    Inventors: Raphael Pappo, Robert B. Garland
  • Total synthesis of 11-alkyl steroids
    Patent number: 3962291
    Abstract: A novel total synthesis of 11-alkyl steroids, utilizing readily available and inexpensive raw materials, is described. The resulting products are useful and novel pharmacological agents possessing, for example, selective hormonal properties.
    Type: Grant
    Filed: September 5, 1974
    Date of Patent: June 8, 1976
    Assignee: G. D. Searle & Co.
    Inventors: Robert B. Garland, Raphael Pappo