Abstract: Personal care compositions comprising a PPARG antagonist, use of such compositions, and methods of marketing such compositions. The personal care compositions can be applied topically, ingested orally, injected, or used as part of a regimen.

Abstract: The present invention relates to the use of alpha (2) macroglobulin complexes isolated from the serum of a mammal. The invention also relates to methods for making such complexes and compositions comprising alpha (2) macroglobulin complexes, isolated from the serum of a mammal, wherein such compositions are used in methods for the treatment and prevention of cancer and infectious disease. The invention also relates to methods for treating and preventing cancer and infectious disease using such complexes comprising, isolated from the serum of a mammal. The invention also encompasses methods for production of alpha (2) macroglobulin complexes.

Abstract: A heatable steering wheel includes a steering wheel blank, a heating mat wrapped around the steering wheel blank, a first, visible hard sheathing whose surface is refinished after having been installed, a second, visible softer sheathing, both of the sheathings abutting each other in an abutting area, and a coupling element in the abutting area. The coupling element, as seen from the outside, has a depression and that, starting from the first sheathing, extends under the abutting area all the way to an abutting edge of the second sheathing. The heating mat extends continuously under the first sheathing and under the coupling element all the way to under the second sheathing.

Abstract: The present invention provides a method and system for evaluating wireless applications utilizing a test console, an application model builder, a test repository manager, a simulator, a test controller, test agents, and a comparator in order to test the performance of a plurality of mobile user devices on a wireless network.

Abstract: The present invention provides methods for generating antigen-reactive cytotoxic T cells in vitro comprising culturing immune cells and antigenic cells that have at least one MHC allele in common (and preferably, are syngeneic), in which the antigenic cells have been treated according to the methods of the invention. The antigenic cells are treated by subjecting them to osmotic shock followed by irradiation. As a result, a subset of T cells are activated and mature into antigen-reactive cytotoxic T cells. The effectiveness of the procedure may be enhanced by repeated restimulations and/or the addition of heat shock protein-peptide complexes. Methods and compositions are also disclosed for the treatment and prevention in a subject of cancer or infectious disease comprising administering to the subject matched cytotoxic T cells that are generated in vitro by the present methods.

Abstract: A process for forming angled trim lines on vehicle frame cross members to mate and secure the ends of the cross members with frame side rail members with a high degree of accuracy and in a cost efficient manner. The process includes the steps of removing portions of the end of a rectangular tube to form angled trim lines and connecting the angled trim lines with the frame side rail member. A cam trimming die is used to form the angled trim lines. The die includes substantially symmetrical drivers, slide cams, and filler cams. The drivers move the slide cams and filler cams in opposing directions. The slide cams carry cutting steels that form the angled trim lines as the slide cam moves. The filler cams support the rectangular tube and produce a sheering effect with the cutting steels as they move past one another.

Abstract: A guide rail, and method of making same, for the guiding and/or tightening of chains that are used in internal-combustion engines, for example, for driving camshafts, auxiliaries or the like is disclosed. For reasons concerning weight and manufacturing, the guide rail consists of a plastic material and is formed by a slideway lining body and a carrier. Both the carrier and the slideway lining body are produced in a progressive manufacturing cycle and are interconnected via one or several dovetailed connections.

Abstract: Air air-cooled multi-cylinder internal combustion engine with a cylinder row through which cooling air flows transversely to the cylinders. Two guide ribs are cast-on at the cooling air discharge side of each cylinder at a distance to one another which are constructed as thin-walled profiles and are angularly bent through about 90.degree. in mutually opposite directions.

Abstract: The camshaft of an internal combustion engine is driven by a chain drive from an adjacent parallel intermediate shaft, which itself is driven with a toothed belt by the engine crankshaft. For a four valve cylinder head having two overhead camshafts, one camshaft is used as the intermediate shaft. By means of a hydraulic tensioning device applied at the chain drive, the relative rotating position of both camshafts and thus also the control time of the valves can be changed.

Abstract: An air-cooled multi-cylinder internal combustion engine includes cylinder heads cast together in a cylinder head casting; the cylinder heads are cooled from the inside by an S-shaped air flow extending between the valves. The cooling air thereby flows-in through an inlet channel at the inlet side of the cylinder heads, is deflected through 90.degree. in a central connecting channel and after a once-more 90.degree. deflection flows into the atmosphere through outlet channels which are formed between the individually cast exhaust gas outlet channels.

Abstract: A pressure relief valve for a lubrication system of an internal combustion engine includes a valve body disposed within a generally cylindrical bore in a housing. The valve body is axially movable within the bore and is provided with a sealing surface on one end. A spring biases the sealing surface against a valve seat in the housing. A guide, which is preferably sleeve-shaped, is non-fixedly arranged within the bore for guiding the axial movement of the valve body and reducing the impact of manufacturing tolerance variations on valve operation. In a preferred embodiment, the sealing surface of the valve body is spherically shaped and the valve seat is conically shaped. A vent passage is provided in the sleeve-shaped guide to equalize pressures within the bore during operation of the valve.

Abstract: Gear belt tensioning apparatus is provided for controlling the tension in a gear belt for driving an internal combustion engine camshaft or the like. This apparatus includes a tension roller which engages directly with the gear belt and which is controlled by a temperature responsive control element. In order to accommodate for changes in temperature of the internal combustion engine, the control element is composed of a plurality of stacked bimetal dish-shaped spring members arranged in a cylindrical recess of an abutment fixed to the engine housing. These spring members are arranged in packets of four members each, which packets are then arranged so as to have the spring members of one packet facing in the opposite direction of the next adjacent packet of spring members.