Abstract: Systems, methods and apparatus for controlling operation of dual fuel engines are disclosed that regulate the fuelling amounts provided by a first fuel and a second fuel during operation of the engine. The first fuel can be a liquid fuel and the second fuel can be a gaseous fuel. The fuelling amounts are controlled to improve operational outcomes of the duel fuel engine.

Abstract: A routing platform coupled to a data network maintains, on local storage of the routing platform, a reflected file system structure corresponding to that of a file system on a network file share. The file system includes a file system object including file system object data, and the reflected file system structure includes a copy of the file system object lacking the file system object data. The routing platform presents, as a proxy, the network file share to a client node communicatively coupled to the routing platform via the data network. The routing platform routes file system protocol traffic between the client node and the network file share, and, if needed, does so by reference to the reflected file system structure.

Abstract: A system and method for triggering on platform usage can include at a platform, receiving and storing a trigger configuration of an account; operating a platform comprising internally executing a process on behalf of an account and publishing at least one event when executing the process; at the platform, incrementing a counter in response to the at least one event and if the stored trigger configuration species a usage key associated with a category of counted events of the at least one event; monitoring counters in a context of an associated trigger; and processing the trigger upon the counter satisfying condition of an associated trigger.

Abstract: A downhole electric submersible pump (ESP) assembly. The downhole ESP assembly comprises a permanent magnet motor (PMM) comprising a first drive shaft, a stator, and a rotor disposed within the stator and comprising a core coupled to the first drive shaft, wherein the core retains a first permanent magnet element within a first magnet pocket defined by the core that extends axially parallel to the first drive shaft and retains a second permanent magnet element within a second magnet pocket defined by the core that extends axially parallel to the first drive shaft; a seal section having a second drive shaft coupled to the first drive shaft; and a pump assembly having a third drive shaft coupled to the second drive shaft.

Abstract: Technologies for sanitizing medical devices are described. In particular, sanitizing systems, components of sanitizing systems, and methods for sanitizing medical devices such as continuous positive airway pressure (CPAP) equipment are described. In embodiments, the sanitizing systems include a sanitizing gas generator and a base including at least one exhaust port and a filter.

Abstract: Systems, methods, and non-transitory computer-readable media can access a plurality of schema-based encodings providing a structured representation of an environment captured by one or more sensors associated with a plurality of vehicles traveling through the environment. The plurality of schema-based encodings can be clustered into one or more clusters of schema-based encodings. At least one scenario associated with the environment can be determined based at least in part on the one or more clusters of schema-based encodings.

Abstract: Described herein is a system for heating and/or cooling a fluid that includes a temperature forcing device having a bottom plate and a top plate hingedly coupled to the bottom plate. At least one of the bottom plate and the top plate has a recess or other area for receiving at least one flexible fluid holder (e.g., a polymer bag). The bottom plate and/or top plate also has at least one protrusion and/or recession in its interior wall(s) such that a fluid passageway in the flexible fluid holder is defined when the fluid holder is placed between the top and bottom plates, and the plates are closed together. The fluid holder then has a fluid inlet for receiving the fluid to be heated and/or cooled and a fluid outlet for delivering the fluid. The fluid, upon being heated and/or cooled by the temperature forcing device, may then be delivered to a patient or may be delivered to another system component, e.g., for additional heating/cooling.

Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating cystic fibrosis, e.g., in subjects having a mutation resulting in F508del, are described.

Abstract: Some implementations include an apparatus configured to, in a wellbore, eliminate voltage on one or more first conductors that are electrically connected to a surface-based power source. The apparatus may include a shorting ring electrically connectable to the first conductors and configured to electrically short the first conductors upon establishing an electrical connection with the first conductors. The apparatus may include a solenoid assembly to actuate in response to power on the first conductors from the surface-based power source. The apparatus may include a pin slider assembly connected to the first conductors and configured to move, in response to actuation by the solenoid assembly, between an electrical connection with the shorting ring and an electrical connection with one or more second conductors that have an electrical connection with a permanent magnet motor winding in the wellbore.

Abstract: An illustrative valve block includes a plate, a fluid transfer block, and a diaphragm. The plate includes a channel configured to receive a first fluid and a recess connected to the channel. The fluid transfer block includes an inlet connection configured to receive a second fluid and an outlet connection. The fluid transfer block also includes a plurality of valve inlet bores connected to the inlet connection. The plurality of valve inlet bores are distributed along at least part of a first curved shape. The fluid transfer block further includes a plurality of valve outlet bores each fluidly connected to the outlet connection. The plurality of valve outlet bores are distributed along at least part of a second curved shape. The diaphragm is between the pressure plate and the fluid transfer block. The plurality of valve inlet bores and the plurality of valve outlet bores adjoin the recess.

Abstract: Aspects of the disclosure relate to a clutch assembly (100) for handling a container, and an associated method for using the clutch assembly. The clutch assembly includes a shaft (102) configured to rotate in a first direction and a second direction, opposite from the first direction. The clutch assembly further includes a clutch coupled to a first end of the shaft. The clutch includes at least two rollers (108) configured to move into a first position, extending radially beyond a periphery of the clutch, and out of the first position, extending radially flush with or inward from the periphery of the clutch.

Abstract: Sun shelves are described. An example sun shelf has a main body and a tubular member. The main body has a first wall, a second wall, a third wall, a fourth wall, a base, and defines a first intake, an outlet, and a recess. The first wall has a first height from the base. The second wall has a second height from the base. The third wall has a third height from the base. The fourth wall has a fourth height from the base. The fourth height is less than the first height, the second height, and the third height. The tubular member is attached to the main body and extends from the first intake to the outlet.

Abstract: This disclosure relates to systems and methods of integrated on-demand labeling of item containers. In particular, this disclosure relates systems and methods for automatically creating and using placards to label, track, and organize item containers and items.

Abstract: Disclosed embodiments relate to a pulsed-power drilling system, in which a pulsed-power drill is conveyed downhole and operated via coiled tubing. The coiled tubing may be configured to simultaneously transmit power and drilling fluid downhole. For example, the coiled tubing may include a flexible hollow fluid tube configured to transport drilling fluid therein, and a flexible cable tube disposed within the fluid tube. The cable tube may have one or more cable disposed within protective tubing, protecting the cables from drilling fluid in the fluid tube. Methods of making and using such coiled tubing with pulsed-power drills are also disclosed.

Abstract: The present invention provides a method for generating a biomarker signature for a subject with cancer. The method comprises calculating an intra-tumour heterogeneity measure and an inter-tumour heterogeneity measure for a plurality of genes. This is done using training data from a plurality of subjects who have had cancer, where the training data comprises gene expression data for a plurality of genes for each subject. A biomarker signature is generated by applying a heterogeneity filter to select genes having both an intra-tumour heterogeneity below an intra-tumour heterogeneity threshold and an inter-tumour heterogeneity above an inter-tumour heterogeneity threshold.

Abstract: A vertical bundle air-cooled heat exchanger, a finned tube assembly for an air cooled condenser and method for forming the same, and a system for removing thermal energy generated by radioactive materials. In one aspect, an air cooled condenser sized for industrial and commercial application includes an inlet steam distribution header for conveying steam, a condensate outlet header for conveying condensate, an array of tube bundles each having a plurality of finned tube assemblies having a bare steel tube with an exposed outer surface and a set of aluminum fins brazed directly onto the tube by a brazing filler metal. The steel tubes may be spaced apart by the aluminum fins and have an inlet end fluidly coupled to the inlet steam distribution header and an outlet end fluidly coupled to the outlet header. A forced draft fan may be arranged to blow air through the tube bundles.

Abstract: Techniques control a utility vehicle. Such techniques involve storing electric power in a lithium battery of the utility vehicle. Such techniques further involve operating a motor controller of the utility vehicle in a normal mode in which the motor controller provides electric power from a lithium battery of the utility vehicle to an electric motor of the utility vehicle to turn one or more ground engaging members of the utility vehicle. Such techniques further involve, after operating the motor controller in the normal operating mode, operating the motor controller in a walkaway mode in which the motor controller configures the electric motor to provide braking torque.

Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.

Abstract: The present application provides the preparation and use of a 3,4-dihydroxyl-N-(1?-benzyl-2?-hydroxyethyl)-2-methyl pyridine chloride. According to the present application, a 3,4-dihydroxyl-N-(1?-benzyl-2?-hydroxyethyl)-2-methyl pyridine chloride is directly synthesized by a one-step reaction, and the compound includes a pharmaceutically acceptable salt thereof. 3,4-dihydroxyl-N-(1?-benzyl-2?-hydroxyethyl)-2-methyl pyridine chloride has been proved to have a good antiparkinsonian activity by animal tests, and it is a class of novel antiparkinsonian drug candidates.