Abstract: A cloud infrastructure orchestration service may maintain a service plan and manifest (SPAM) corresponding to a service to be bootstrapped (e.g., provisioned and deployed) to a cloud computing environment (e.g., to a data center). The service plan may specify a deterministic order of releases for performing a process to fully bootstrap the service using one or more build milestones and one or more execution units, each execution unit specifying ordered steps for transitioning between build milestones Each step may reference one or more execution target checkpoint transitions, which in turn reference an alias of a configuration file that defines a release. A manifest may be used to identify the configuration files and artifacts to be used by the releases and to validate the service plan. A SPAM may be used to reduce/eliminate nondeterministic behavior of previous orchestration systems and to provide visualizations of the bootstrapping process at different granularities.

Abstract: A cloud infrastructure orchestration service (CIOS) may track build progress made by any suitable number of regional orchestrators. An orchestrator control plane may be configured to generate a region build plan for bootstrapping a plurality of services within a data center. The orchestrator control plane may instruct a region orchestrator to execute a build according to the build plan. The region orchestrator may be configured to update an execution state corresponding to the execution of the region build plan as it executes steps of the ordered steps of the region build plan. At any suitable time (e.g., when executing one of the steps fails), intervention data may be received with which a new region build plan may be generated. The new region build plan may be used for subsequent execution of the region build. This may enable run-time corrections to be made.

Abstract: A cloud infrastructure orchestration service (CIOS) may track build progress made by any suitable number of regional orchestrators. The cloud infrastructure orchestration system may include any suitable number of regional orchestrators, each regional orchestrator executing in an isolated hosting environment (e.g., a service cell isolated from other service cells). An orchestrator control plane may be configured to generate a build plan for bootstrapping a plurality of services within a data center, the build plan may be generated based at least in part on a service build definition of a plurality of service build definitions, the service build definition specifying a deterministic process for bootstrapping a service of the plurality of services. The orchestrator control plane may instruct a regional orchestrator to perform bootstrapping operations according to the build plan and may track the progress of the bootstrapping operations on an ongoing basis.

Abstract: Security event data from each of a plurality of security data sources is received, each unit of the security event data being associated with a security event involving one or more human users included in a monitored set of human users. The security event data is used to generate for each of at least a subset of the monitored set of human users a user-specific security risk score that is determined based at least in part on: a level of access to protected resources that a user has; an attack type that has been attempted with respect to the user; and an action taken by the user, as reflected in the security event data associated with the user from two or more of said security data sources.

Abstract: The invention provides methods for detecting single nucleotide variants in lung cancer, especially stage 3a lung adenocarcinoma and lung squamous cell carcinoma. Additional methods and compositions, such as reaction mixtures and solid supports comprising clonal populations of nucleic acids, are provided.

Abstract: The present disclosure relates to a package architecture and a method for making the same. The disclosed package architecture includes a package carrier, a first device die and a second device die mounted on the package carrier, and a heat spreader. The first device die includes a first device body with a thickness between 5 ?m and 130 ?m, a die carrier, and an attachment section between the first device body and the die carrier, while the second device die includes a second device body. The first device body and the second device body are formed of different materials. A top surface of the die carrier of the first device die and a top surface of the second device body of the second device die are substantially coplanar. The heat spreader resides over the top surface of the die carrier and the top surface of the second device body.

Abstract: Methods and compositions for modulating a target genome are disclosed.

Abstract: A vehicle includes a first seat. A seat base is selectively coupled to the first seat via an engaging member extending from a proximal end of the seat base. The seat base has an attached configuration and a detached configuration. The seat base couples with the first seat and forms a second seat facing away from the first seat in the attached configuration. The seat base is decoupled from the first seat in the detached configuration. A backrest is common to the first and second seats in the attached configuration. A frame structure operably couples the first seat with the vehicle. The frame structure includes a receiving member interfacing with the seat base. The engaging member engages the receiving member to couple the seat base with the backrest.

Abstract: A seating assembly for a vehicle includes a backrest extending between a first surface and a second surface. The second surface opposes the first surface. A first seat base operably couples with the backrest to form a first seat of the seating assembly. The backrest is pivotable between a first use position and a second use position. A second seat base is operably coupled via a connection interface with the backrest. The second seat base and the backrest form a second seat of the seating assembly in the second use position. The second seat faces away from the first seat in the second use position. A cross-sectional plane intersecting each of the first surface and the second surface defines a cross-sectional area of the backrest that remains constant between the first use position and the second use position of the backrest.

Abstract: A seating assembly for a vehicle includes a first seat including a first seat base coupled with a backrest. A second seat includes a seat back and a second seat base pivotably coupled with the seat back and moveable between a stowed position and a deployed position. A locking feature between the second seat base and the seat back is moveable between a locked position and an unlocked position. The locking feature engages the second seat base in the locked position. The locking feature is disengaged from the second seat base in the unlocked position. A connection interface between the backrest and the seat back includes an engaging member and a receiving member. The engaging member selectively engages the receiving member to secure the second seat to the first seat in an attached configuration.

Abstract: Systems and methods for informed mobility platform for an item processing supervisor within a distribution facility are disclosed. In one embodiment, a supervisor mobile terminal for electronically managing item processing activities associated with a distribution facility is provided. The terminal may include a transceiver circuit configured to wirelessly communicate with a server computer a plurality of sets of data relating to the item processing activities. The terminal may further include a user interface configured to display the plurality of sets of data and a controller in data communication with the transceiver circuit and the user interface. The controller may be configured to control the user interface to modify the at least one set of data and control the transceiver circuit to wirelessly communicate the modified data with the server computer such that the at least one set of data stored in the server computer is updated with the modified data.

Abstract: An interposer card and a virtualization offloading card are provided for installation in a third-party server to integrate the third-party server into a cloud service provider network. The interposer card includes a baseboard management controller that interfaces with a management console of the cloud service provider network. This allows the third-party server to be converted into a server controlled by the cloud service provider network. Additionally, the baseboard management controller of the interposer card acts as a firewall between the third-party server and a management control network of the cloud service provider network. The interposer card and the virtualization offloading card are installed in a chassis of the third-party server via an expansion slot without requiring modification of the hardware or firmware of the third-party server.

Abstract: A well pump includes a plurality of diffusers, wherein each diffuser comprises a first threaded coupling on one longitudinal end and a second threaded coupling on an opposed longitudinal end. An impeller is disposed in each diffuser. The plurality of diffusers are coupled end to end to form a pump housing, in which the first threaded coupling on one diffuser is threadedly engaged to the second threaded coupling on adjacent diffuser.

Abstract: An actuator apparatus includes an actuator rod with an interior cavity and a set of rod holes. Each rod hole of the set of rod holes extends through the actuator rod to the cavity where the set of rod holes are positioned along a line. The actuator apparatus includes a light assembly positioned to light the cavity. The actuator apparatus includes an actuator block with an opening sized to conform to an outer surface of the actuator rod and a light sensor positioned in the actuator block to sense light coming through a rod hole aligned with the light sensor. The actuator apparatus includes a verification module with a light modulator that modulates light of the light assembly to transmit a position signal, and a verification circuit that transmits a verification signal in response to the light sensor receiving the position signal.

Abstract: A valve block includes a fluid-transfer plate with multiple inlet bores connecting to a common inlet channel, and multiple outlet bores connecting to a common outlet channel. The inlet bores and the outlet bores are arranged in a curved shape. The valve block also includes a pressure plate and diaphragm aligned and connected to the fluid-transfer plate in a way that allows pressurized material in the pressure plate to control the state of the channels formed by the inlet and outlet bores.

Abstract: A downhole electric submersible pump (ESP) assembly. The downhole ESP assembly comprises a hybrid permanent magnet motor (PMM) comprising a first drive shaft, a stator, and a rotor comprising a first permanent magnet element, a second permanent magnet element, and an induction squirrel cage, wherein the rotor is mechanically coupled to the first drive shaft and disposed within the stator; a seal section having a second drive shaft coupled to the first drive shaft; and a pump assembly having a third drive shaft coupled to the second drive shaft.

Abstract: An electric pushback vehicle includes a frame having a forward portion and a rear portion. The vehicle further includes front drive axle and a rear drive axle configured to communicate power to ground engaging members. A traction battery is housed within the electric pushback vehicle and provides electric power to an electric motor to drive an output shaft. A transmission is connected to receive mechanical power from the electric motor through a torque converter.

Abstract: Provided are compositions and methods for preparing and identifying antibodies having CDR3s that vary in sequence and in length from very short to very long which in certain embodiments may bind to a carbohydrate moiety or the active site of an enzyme. Libraries coding for antibodies with the CDR3s are also provided. The libraries can be provided by modifying a pre-existing nucleic acid library.

Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject.

Abstract: A method of forming a structural web for a wind turbine blade comprises providing a web member having a web portion and a flange portion extending away from each other, where 5 a heel of substantially curvilinear form is located between the web portion and the flange portion. A planar flange extender comprising a cured composite material is arranged together with the web member with the flange extender positioned adjacent to the flange portion so that a portion of the flange extender projects past the heel and away from the web portion. The flange extender is integrated with the web member in a resin matrix, or 10 with an adhesive, to form the structural web. A structural web and a wind turbine blade comprising the web is disclosed.