Abstract: In an embodiment, an electronic component includes a power semiconductor device embedded in a dielectric core layer and at least one contact layer protruding from a first side face of the dielectric core layer. The contact layer includes an electrically insulating layer and at least one contact pad arranged on the electrically insulating layer. The at least one contact pad is electrically coupled with the power semiconductor device.

Abstract: In an embodiment, a method includes inserting an electronic component including a power semiconductor device embedded in a dielectric core layer into a slot in a side face of a circuit board. The inserting the electronic component causes one or more electrically conductive contacts on one or more surfaces of the electronic component to electrically couple with one or more corresponding electrical contacts arranged on one or more surfaces of the slot.

Abstract: Described is an apparatus for intraocular injection comprising a body adapted to accommodate a syringe having a needle, a needle cover adapted to cover the needle, and two or more resilient arms extending distally from the body. The body has a longitudinal axis. The arms are adapted to selectively engage the needle cover.

Abstract: An improved drink can is disclosed wherein the drink can has a drink opening and a vent opening which are positioned opposite from each other with respect to a central portion of a top end of a drink can. The tab is attached to the central portion and can be pulled upward to open the drink opening then pushed back downward to open the vent opening. To aid in opening the vent opening with the tab, the vent opening may have a ridge to provide additional leverage when the tab pushes downward on a score line that defines the vent opening. The tab may be enlarged so that upon breakage of the score line to the vent opening, the tab contacts the top end of the can and does not allow the user's finger to proceed into the vent opening and possibly cut the user's finger.

Abstract: A drink can has a drink opening and a vent opening. These openings are positioned opposite from each other with respect to a central portion of a top end of a drink can. The tab is attached to the central portion and can be pulled upward to open the drink opening then pushed back downward to open the vent opening. To aid in opening the vent opening with the tab, the vent opening may have a ridge to provide additional leverage when the tab pushes downward on a score line that defines the vent opening. The tab may be enlarged so that upon breakage of the score line to the vent opening, the tab contacts the top end of the can and does not allow the user's finger to proceed into the vent opening and possibly cut the user's finger.

Abstract: A method of increasing muscle mass and strength in mammals by orally administering a therapeutically effective amount of phosphatidic acid. The phosphatidic acid is preferably administered as a plurality of doses per day with at least one dose being administered during the anabolic window following exercise. Preferably, the method further includes the cotemporaneous administration of a therapeutically effective amount of creatine, optionally as phosphatidylcreatine. In addition or in the alternative, the method further includes the cotemporaneous administration of a therapeutically effective amount of leucine, optionally as phosphatidylleucine.

Abstract: Described is an apparatus for intraocular injection comprising a body adapted to accommodate a syringe having a needle, an outer sleeve telescopically coupled to the body, and at least two arms hingedly coupled to the outer sleeve. Each of the arms comprises a medial portion adapted to encase at least a portion of the needle. When the body moves distally relative 10 to said outer sleeve, the body engages the arms separating the medial portions.

Abstract: Described is an apparatus for intraocular injection comprising an inner sleeve adapted to accommodate a syringe having a needle, a needle cover adapted to cover the needle, and an outer sleeve telescopically coupled to the inner sleeve. The inner sleeve includes a distal end adapted to engage the needle cover. Movement of the inner sleeve relative to the outer sleeve causes removal of the needle cover from the needle.

Abstract: Described is a medicament delivery device comprising a body adapted to be placed on the eye and a reservoir formed in the body containing a medicament. The body has a first surface adapted to contact at least a portion of the eye and be centered around a cornea. At least one projection is formed on the first surface. The projection includes a channel adapted to create a fluid flow path for the medicament from the reservoir to a terminal end of the projection.

Abstract: Small molecule inhibitors of XBP1 splicing by IRE1 are provided, as well as methods for their use in treating or preventing cancer (e.g., endocrine resistant breast cancer), diabetes, and obesity.

Abstract: An apparatus for intraocular injection comprising a body adapted to accommodate an injection device, a displacement device coupled to a distal end of the body, and a sleeve coupled to the body and axially moveable relative to the body. The displacement device includes at least one rotatable member adapted to contact a superficial layer of an eye, and the sleeve engages and causes rotation of the at least one rotatable member as the sleeve moves from a first axial position to a second axial position. Rotation of the at least one rotatable member displaces the superficial layer relative to an underlying layer of the eye.

Abstract: A venting blade assembly for poultry processing. The venting blade assembly includes a projecting cylindrical barrel having an open first end. An attachment mechanism attaches an opposed second end of the cylindrical barrel to an axial advancement and rotation mechanism. A flat circular abutment shoulder at the first end is substantially perpendicular to the cylindrical barrel in order to engage the poultry. The first end of the cylindrical barrel also includes a beveled circular edge. A plurality of helical recesses in the first end of the cylindrical barrel forms a plurality of cutting tips.

Abstract: An improved drink can is disclosed wherein the drink can has a drink opening and a vent opening which are positioned opposite from each other with respect to a central portion of a top end of a drink can. The tab is attached to the central portion and can be pulled upward to open the drink opening then pushed back downward to open the vent opening. To aid in opening the vent opening with the tab, the vent opening may have a ridge to provide additional leverage when the tab pushes downward on a score line that defines the vent opening. The tab may be enlarged so that upon breakage of the score line to the vent opening, the tab contacts the top end of the can and does not allow the user's finger to proceed into the vent opening and possibly cut the user's finger.

Abstract: An apparatus for intraocular injection comprising a body adapted to accommodate an injection device and a displacement device coupled to a distal portion of the body. The displacement device comprises a first portion and a second portion connected to the first portion. Axial movement of the first portion within the body in a distal direction causes the second portion to displace a superficial layer of an eye relative to an underlying layer of the eye.

Abstract: An improved drink can with a drink opening and a vent opening are positioned opposite from ouch other with respect to a central portion of a top end of a drink can. The tab is attached to the central portion and can be pulled upward to open the drink opening then pushed back downward to open the vent opening. To aid in opening the vent opening with the tab, the vent opening may have a ridge to provide additional leverage when the tab pushes downward on a score line that defines the vent opening. The tab may be enlarged so that upon breakage of the score line to the vent opening, the tab contacts the top end of the can and does not allow the user's finger to proceed into the vent opening and possibly cut the user's finger.

Abstract: An improved drink can is disclosed wherein the drink can has a drink opening and a vent opening which are positioned opposite from each other with respect to a central portion of a top end of a drink can. The tab is attached to the central portion and can be pulled upward to open the drink opening then pushed back downward to open the vent opening. To aid in opening the vent opening with the tab, the vent opening may have a ridge to provide additional leverage when the tab pushes downward on a score line that defines the vent opening. The tab may be enlarged so that upon breakage of the score line to the vent opening, the tab contacts the top end of the can and does not allow the user's finger to proceed into the vent opening and possibly cut the user's finger.

Abstract: A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.

Abstract: A drink can having both drinking and venting openings is provided. The two openings are positioned a distance from one another with respect to a central portion of a top end of a drink can. A single tab is attached to the central portion of the top end, and can be pulled upward to open the drink opening, then pushed downward to open the vent opening. To aid in opening the vent opening with the single tab, the venting portion is provided with a protrusion comprising opposed sloping sides to focus the force when the tab is pushed downward on a score line that defines the vent opening. Advantageously, the tab may be larger than the vent opening so that, upon breakage of the vent opening score line, the tab contacts the top end of the can, thereby preventing the user's finger from proceeding into sharp portions of the vent opening.

Abstract: An electronic device includes at least one terminal formed on the electronic device. The electronic device also includes at least one of a semiconductor device, an integrated circuit chip, and a computer. A seamless conductive mesh is formed on at least one surface of the electronic device. The conductive mesh is in electrical contact with the terminal. The terminal facilitates electrical conduction between the conductive mesh and an electrical detection circuit. The electronic device also may include a pattern having traces formed on at least two surfaces where each of the traces includes a continuous loop of conductive material is formed on at least two surfaces. The electronic device also may include a first plurality of conductive loops formed on the electronic device that are continuous and surround the electronic device in a first direction and a second plurality of conductive loops formed on the electronic device that are continuous and surround the electronic device in a second direction.

Abstract: The invention is directed to a process that combines the solvent deasphalting with resin hydrotreatment so as to reduce the costs associated with performing each of the steps separately. The integrated process of the invention permits higher product yields coupled with lower energy and transportation costs.