Abstract: A valve seat apparatus for use with fluid valves is described. An example disclosed valve seat apparatus includes a seat ring having an outer surface that includes a first annular recess at a first end of the seat ring, where the first annular recess is to receive a portion of a cage, a second annular recess proximate a second end of the seat ring opposite the first end, and where the second annular recess defines a groove in the outer surface of the seat ring, and a third annular recess adjacent the second annular recess. The example disclosed valve seat apparatus also includes a first seal assembly disposed in the third annular recess and a retainer disposed in the second annular recess to retain the seal assembly in the third annular recess.

Abstract: The present invention discloses compositions of novel DYRK1A protein inhibitors based on a 3,5-diarylazaindole motif and their preparation and use as medications in the treatment of cognitive disorders associated with dysfunction of DYRK1A protein, with Down's syndrome and with Alzheimer's disease.

Abstract: A valve seat apparatus for use with fluid valves is described. An example disclosed valve seat apparatus includes a seat ring having an outer surface that includes a first annular recess at a first end of the seat ring, where the first annular recess is to receive a portion of a cage, a second annular recess proximate a second end of the seat ring opposite the first end, and where the second annular recess defines a groove in the outer surface of the seat ring, and a third annular recess adjacent the second annular recess. The example disclosed valve seat apparatus also includes a first seal assembly disposed in the third annular recess and a retainer disposed in the second annular recess to retain the seal assembly in the third annular recess.

Abstract: A valve seat apparatus for use with fluid valves is described. An example valve seat apparatus includes a seat ring having an outer surface that includes a first annular recess and a second annular recess adjacent the first annular recess to form a stepped profile. A seal assembly is disposed within the first groove and a retainer is disposed in the second annular recess to retain the seal assembly in the first annular recess of the seat ring.

Abstract: The present invention relates to a compound of formula (I?) or a pharmaceutically acceptable salt, solvate or hydrate thereof, in which: X3 is F, OH or SH, Y3 is F, OH or SH, X1, X2, X4, X5, Y1, Y2, Y4 and Y5 are, independently of one another, H, F, Cl, Br, OH or SH, and 1 to 2 groups among the X1, X2, X4 and X5 radicals are other than H and/or 1 to 2 groups among the Y1, Y2, Y4 and Y5 radicals are other than H. The present invention also relates to a compound of formula (I?) for use as a medicament, in particular in the prevention and/or treatment of cognitive disorders associated with a dysfunction of the Dyrk1A protein.

Abstract: A keying mechanism within a device bay allows a device connector of a device to make electrical connection with the device bay connector when a key slot of the device is located in one of a plurality of predetermined locations on the device. The keying mechanism prevents the device connector from making electrical connection with the device bay connector when the device does not have a key slot in any of the predetermined locations.

Abstract: A keying mechanism within a device bay allows a device connector of a device to make electrical connection with the device bay connector when a key slot of the device is located in one of a plurality of predetermined locations on the device. The keying mechanism prevents the device connector from making electrical connection with the device bay connector when the device does not have a key slot in any of the predetermined locations.

Abstract: A valve seat apparatus for use with fluid valves is described. An example valve seat apparatus includes a seat ring having an outer surface that includes a first annular recess and a second annular recess adjacent the first annular recess to form a stepped profile. A seal assembly is disposed within the first groove and a retainer is disposed in the second annular recess to retain the seal assembly in the first annular recess of the seat ring.

Abstract: Grinding media, including shaped media such as spheres or rods ranging in size from about 0.5 micron to 100 mm in diameter, are formed from a multi-carbide material consisting essentially of two or more carbide-forming elements and carbon, with or without carbide-forming elements in their free elemental state. The media have extremely high mass density, extreme hardness, and extreme mechanical toughness.

Abstract: Embodiments of the invention provide a method and an apparatus for utilizing a microcontroller to provide an automatic order and timing power and reset sequencer. A first inter-integrated circuit (I2C) register table containing a modifiable system power-up sequence is accessed. An automatic system power-up operation is then performed in the order of the power-up sequence defined by the first I2C register table.

Abstract: Grinding media, including shaped media such as spheres or rods ranging in size from about 0.5 micron to 100 mm in diameter, are formed from a multi-carbide material consisting essentially of two or more carbide-forming elements and carbon, with or without carbide-forming elements in their free elemental state. The media have extremely high mass density, extreme hardness, and extreme mechanical toughness.

Abstract: Grinding media, including shaped media such as spheres or rods ranging in size from about 0.5 micron to 100 mm in diameter, are formed from a multi-carbide material consisting essentially of two or more carbide-forming elements and carbon, with or without carbide-forming elements in their free elemental state. The media have extremely high mass density, extreme hardness, and extreme mechanical toughness.

Abstract: Grinding media, including shaped media such as spheres or rods ranging in size from about 0.5 micron to 100 mm in diameter, are formed from a multi-carbide material consisting essentially of two or more carbide-forming elements and carbon, with or without carbide-forming elements in their free elemental state. The media have extremely high mass density, extreme hardness, and extreme mechanical toughness.

Abstract: A plurality of conductive pads of an apparatus in one example are disposed on a circuit board in a predetermined arrangement compatible with an arrangement of probes on an external test connector. One or more of the plurality of conductive pads is disposed on an embedded layer of the circuit board.

Abstract: Grinding media, including shaped media such as spheres or rods ranging in size from about 0.5 micron to 100 mm in diameter, are formed from a multi-carbide material consisting essentially of two or more carbide-forming elements and carbon, with or without carbide-forming elements in their free elemental state. The media have extremely high mass density, extreme hardness, and extreme mechanical toughness.

Abstract: Small particle compositions including nanoparticle compositions are provided. The particle compositions, in some cases, are characterized by having an extremely small average particle size (e.g., 150 nanometers or less). The small particles may comprise a semiconductor material and/or a light-emitting material. In some embodiments, the particles may be in the form a preferred shape including platelets, amongst others. The small particle compositions may be produced in a milling process. In some embodiments, the milling process uses preferred types of grinding media to form milled particles having desired characteristics (e.g., particle size, shape). The small (or nano) particle compositions may be used in a variety of different applications including light-emitting applications. In certain applications, it may be desirable to form thin films from the small particle compositions.

Abstract: Grinding media, including shaped media such as spheres or rods ranging in size from about 0.5 micron to 100 mm in diameter, are formed from a multi-carbide material consisting essentially of two or more carbide-forming elements and carbon, with or without carbide-forming elements in their free elemental state. The media have extremely high mass density, extreme hardness, and extreme mechanical toughness.

Abstract: Embodiments of the invention provide a method and an apparatus for utilizing a microcontroller to provide an automatic order and timing power and reset sequencer. A first inter-integrated circuit (I2C) register table containing a modifiable system power-up sequence is accessed. An automatic system power-up operation is then performed in the order of the power-up sequence defined by the first I2C register table.

Abstract: Small particle compositions are provided. The particles may have one or more desired features related to particle morphology, topology and crystallographic orientation. The small particle size coupled with such feature(s) can lead to significant property advantages in a variety of different applications including catalytic applications.

Abstract: Coal particle compositions are provided. The coal particle compositions, in some cases, are characterized by having an extremely small average particle size (e.g., 1.0 micron or less) and a high average surface area (e.g., greater than 3 m2/g). The small particle size and high surface area can lead to significant property advantages including more efficient combustion, more effective fractional distillation, and enhanced pollution separation, amongst others. The coal particle compositions may be produced in a milling process that uses preferred grinding media (e.g., high density grinding media) to reduce feed coal particles to a desired final particle size. The coal particle compositions may be used in a variety of different applications including fuel and non-fuel uses.