Abstract: Systems and apparatus for configurable current steering in a printed circuit board (PCB) include a plurality of power sources each including a power output, and a plurality of power loads each including a power input. A power distribution element includes a switching array configurable to selectively couple a respective power output of each of the plurality of power sources to a respective power input of each of the plurality of power loads. A controller is configured to determine that a first power load of the plurality of power loads is included in a first system configuration, and provide a control signal to the power distribution element to configure the switching array to couple a respective power output of a first power source of the plurality of power sources to a respective power input of the first power load.

Abstract: The present disclosure relates to methods for detecting unique genetic signatures derived from markers such as, for example, mutations, somatic or germ-line, in nucleic acids obtained from biological samples. The sensitivity of the methods provides for detection of mutations associated with a disease, e.g., cancer mutations, or with inherited disease, e.g., an autosomal recessive disease, in a noninvasive manner at ultra-low proportions of sequences carrying mutations to sequences carrying normal, e.g., non-cancer sequences, or a reference sequence, e.g., a human reference genome.

Abstract: A system for generating hydrogen includes a chamber configured to receive a fluid, and a first end plate and a second end plate configured to be positioned within the chamber and defining a longitudinal axis between first end plates. The system further includes a plurality of plates positioned between the first end plate and the second end plate, configured to be submerged in the fluid, and including: a cathode plate, an anode plate, and a semi-permeable membrane plate positioned between the cathode plate and the anode plate and configured to allow the passage of some elements therethrough and to block the passage of other elements therethrough. The system further includes at least one plasma source configured to be positioned within the fluid on an axial end of the plurality of plates and configured to generate a directed flow of plasma through the chamber along the axis.

Abstract: Techniques for determining ground surface voxels based on multiresolution planes are discussed herein. Such multiresolution planes may be generated, validated, and used to connect voxels associated with the ground. In some examples, a vehicle may use capture or otherwise receive lidar data while traversing within a driving environment. The vehicle may associate the lidar data with a voxel space. Voxels can be associated with a cell of a multiresolution grid and the vehicle may determine multiresolution planes associated with the multiresolution space. For example, the vehicle may determine a first plane associated with a first resolution level, in addition to determining a plurality of planes associated with a second resolution level. The vehicle may determine the validity of the plane(s) at the various resolution levels. Based on the validity of the planes, the vehicle may connect the valid planes that are associated with the ground surface.

Abstract: A technique automatically identifies and resolves prohibited maneuvers in candidate routes generated by a routing system. Examples of prohibited maneuvers include traveling over a non-navigable path, traveling in an incorrect direction over a roadway, and an improper turn. The technique determines whether the candidate routes contain prohibited maneuvers by comparing the candidate routes with plural types of route-related validation data in plural respective validation processes. For example, a first validation process compares the candidate routes with a collection of GPS traces. A second validation process compares the candidate routes with map reference data. The technique further includes provisions for correcting the causes of identified prohibited maneuvers. Overall, the technique reduces the amount of manual effort involved in verifying the accuracy of routes produced by the routing system, and improves the accuracy, reliability, and safety of the routing system.

Abstract: In some general aspects, a surface of a structure within a chamber of an extreme ultraviolet (EUV) light source is cleaned using a method. The method includes generating a plasma state of a material that is present at a location adjacent to a non-electrically conductive body that is within the chamber. The generation of the plasma state of the material includes electromagnetically inducing an electric current at the location adjacent the non-electrically conductive body to thereby transform the material that is adjacent the non-electrically conductive body from a first state into the plasma state. The plasma state of the material includes plasma particles, at least some of which are free radicals of the material. The method also includes enabling the plasma particles to pass over the structure surface to remove debris from the structure surface without removing the structure from the chamber of the EUV light source.

Abstract: The present disclosure relates to a laboratory execution system that provides for automation of laboratory processes. A centralized data management system may be dynamically updated and used to facilitate management of components of the laboratory execution system, such as an automation system and an analytics results management system that may facilitate complex analytical functions, such as synthesizing raw test data. Potential workflows include the detection of specific molecules of interest.

Abstract: The present invention provides for methods and compositions for one-pot Golden Gate cloning, or conventional two-pot restriction enzyme cloning, regardless of internal restriction sites. It uses modified nucleotides during PCR of DNA, or through post-hoc enzymatic modification of already existing DNA, wherein the modification blocks the internal restriction sites while leaving the flanking restriction sites unblocked.

Abstract: An example method includes providing, to a sequence model (i) a plurality of few-shot prompts, wherein each prompt comprises a demonstration passage, a demonstration task, and a demonstration query, wherein the demonstration task describes a type of retrieval, and wherein the demonstration query is relevant to the demonstration task, and (ii) a plurality of passages sampled from a corpus of passages. The method also includes receiving, from the sequence model and for the plurality of passages and based on the plurality of few-shot prompts, a respective plurality of predicted task-query pairs, the sequence model having been prompted to predict a task based on an input passage, and predict an output query relevant to the predicted task. The method further includes generating a synthetic training dataset comprising the plurality of passages and the respective plurality of predicted task-query pairs. The method also includes providing the synthetic training dataset.

Abstract: The present disclosure relates to a laboratory execution system that provides for automation of laboratory processes. A centralized data management system may be dynamically updated and used to facilitate management of components of the laboratory execution system, such as an automation system and an analytics results management system that may facilitate complex analytical functions, such as synthesizing raw test data. Potential workflows include the detection of specific molecules of interest.

Abstract: The present disclosure relates to a laboratory execution system that provides for automation of laboratory processes. A centralized data management system may be dynamically updated and used to facilitate management of components of the laboratory execution system, such as an automation system and an analytics results management system that may facilitate complex analytical functions, such as synthesizing raw test data. Potential workflows include the detection of specific molecules of interest.

Abstract: The present disclosure relates to a laboratory execution system that provides for automation of laboratory processes. A centralized data management system may be dynamically updated and used to facilitate management of components of the laboratory execution system, such as an automation system and an analytics results management system that may facilitate complex analytical functions, such as synthesizing raw test data. Potential workflows include the detection of specific molecules of interest.

Abstract: A radiation shield assembly is described, configured to block radiation emanating from a radiation source from reaching a user. Two shields are supported by a support arm, and are configured to rotate and translate relative to one another about the support arm's longitudinal axis. This allows the shield to be easily configured and reconfigured as necessary to visualize various parts of a patient's body via radiography.

Abstract: Systems and other embodiments described herein relate to vehicle collision energy absorption with increased airflow towards an engine compartment of a vehicle. In one embodiment, the system includes a front energy absorber with a first top surface having an angle and a rear energy absorber with a second top surface that is curved. The rear energy absorber is separated from the front energy absorber by a gap and a plane of the first top surface is tangential to the second top surface.

Abstract: In some general aspects, a surface of a structure within a chamber of an extreme ultraviolet (EUV) light source is cleaned using a method. The method includes generating a plasma state of a material that is present at a location adjacent to a non-electrically conductive body that is within the chamber. The generation of the plasma state of the material includes electromagnetically inducing an electric current at the location adjacent the non-electrically conductive body to thereby transform the material that is adjacent the non-electrically conductive body from a first state into the plasma state. The plasma state of the material includes plasma particles, at least some of which are free radicals of the material. The method also includes enabling the plasma particles to pass over the structure surface to remove debris from the structure surface without removing the structure from the chamber of the EUV light source.

Abstract: The present disclosure introduces systems and related methods. Each system includes a first water electrolysis subsystem and a second water electrolysis subsystem. The first water electrolysis subsystem electrolyzes water to produce hydrogen and waste thermal energy. The second water electrolysis subsystem electrolyzes water to produce hydrogen utilizing the waste thermal energy produced by the first water electrolysis subsystem.

Abstract: A technique generates estimated time-of-arrival (ETA) information to assist in navigating from one physical location to another. The technique uses a computer-implemented route-finding engine to identify a route between a specified starting location and an ending location of a trip. The route includes a sequence of segments. The technique then uses a machine-trained model to map information regarding the segments to ETA information. The ETA information provides an estimate of a time-of-arrival for the trip as a whole. The ETA information also provides an estimate of parameters that describe the level of confidence of the time-of-arrival estimate for the trip. A training system produces the machine-trained model using a loss function, part of which models the time-of-arrival for the trip as a mixture of distributions.

Abstract: A radiation shield assembly is described, configured to block radiation emanating from a radiation source from reaching a user. Two shields are supported by a support arm, and are configured to rotate and translate relative to one another about the support arm's longitudinal axis. This allows the shield to be easily configured and reconfigured as necessary to visualize various parts of a patient's body via radiography.

Abstract: There are disclosed certain substituted pyrazine-2-carboxamides of Formula (I), and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are inhibitors of hematopoietic progenitor kinase 1 (HPK1) and are thereby particularly useful in the treatment or prophylaxis of cancer.

Abstract: A system for monitoring and optimizing fuel consumption by a genset at an oil rig is described. Gensets require large amounts of fuel to initiate and to maintain in a standby, idling position. The system accesses data in a drill plan to determine the present and future power requirements and initiates gensets if needed; otherwise gensets can be shut down. Excess power can be stored in a power storage unit such as a capacitor, battery, or a liquid air energy storage unit.