Abstract: A cutting element assembly includes a cutter support including a cutter bore. A cutting element is in the cutter bore and a resilient element is integral with the cutter support. The resilient element is longitudinally compressible and has a displacement of greater than 0.1 mm and optionally less than 2 mm. Another cutting assembly includes a cutter support coupled to multiple cutting elements. A resilient element of the cutter support is compressible based on a force applied to the cutter support through one or more of the cutting elements. The resilient element can include a slit in the cutter support. A slit may, for instance, extend perpendicular or transverse to an axis of the cutting elements and allow the cutter support to flex and close off or reduce a size of the slit when forces act on one or more of the cutting elements.

Abstract: A radiation shield assembly is described, configured to block radiation emanating from a radiation source from reaching a user. Two shields are supported by a support arm, and are configured to rotate and translate relative to one another about the support arm's longitudinal axis. This allows the shield to be easily configured and reconfigured as necessary to visualize various parts of a patient's body via radiography. Sterile coverings are provided to ensure asepsis during a surgical procedure.

Abstract: Techniques for determining ground surface voxels based on multiresolution planes are discussed herein. Such multiresolution planes may be generated, validated, and used to connect voxels associated with the ground. In some examples, a vehicle may use capture or otherwise receive lidar data while traversing within a driving environment. The vehicle may associate the lidar data with a voxel space. Voxels can be associated with a cell of a multiresolution grid and the vehicle may determine multiresolution planes associated with the multiresolution space. For example, the vehicle may determine a first plane associated with a first resolution level, in addition to determining a plurality of planes associated with a second resolution level. The vehicle may determine the validity of the plane(s) at the various resolution levels. Based on the validity of the planes, the vehicle may connect the valid planes that are associated with the ground surface.

Abstract: A technique automatically identifies and resolves prohibited maneuvers in candidate routes generated by a routing system. Examples of prohibited maneuvers include traveling over a non-navigable path, traveling in an incorrect direction over a roadway, and an improper turn. The technique determines whether the candidate routes contain prohibited maneuvers by comparing the candidate routes with plural types of route-related validation data in plural respective validation processes. For example, a first validation process compares the candidate routes with a collection of GPS traces. A second validation process compares the candidate routes with map reference data. The technique further includes provisions for correcting the causes of identified prohibited maneuvers. Overall, the technique reduces the amount of manual effort involved in verifying the accuracy of routes produced by the routing system, and improves the accuracy, reliability, and safety of the routing system.

Abstract: In some general aspects, a surface of a structure within a chamber of an extreme ultraviolet (EUV) light source is cleaned using a method. The method includes generating a plasma state of a material that is present at a location adjacent to a non-electrically conductive body that is within the chamber. The generation of the plasma state of the material includes electromagnetically inducing an electric current at the location adjacent the non-electrically conductive body to thereby transform the material that is adjacent the non-electrically conductive body from a first state into the plasma state. The plasma state of the material includes plasma particles, at least some of which are free radicals of the material. The method also includes enabling the plasma particles to pass over the structure surface to remove debris from the structure surface without removing the structure from the chamber of the EUV light source.

Abstract: The present invention provides for methods and compositions for one-pot Golden Gate cloning, or conventional two-pot restriction enzyme cloning, regardless of internal restriction sites. It uses modified nucleotides during PCR of DNA, or through post-hoc enzymatic modification of already existing DNA, wherein the modification blocks the internal restriction sites while leaving the flanking restriction sites unblocked.

Abstract: A radiation shield assembly is described, configured to block radiation emanating from a radiation source from reaching a user. Two shields are supported by a support arm, and are configured to rotate and translate relative to one another about the support arm's longitudinal axis. This allows the shield to be easily configured and reconfigured as necessary to visualize various parts of a patient's body via radiography.

Abstract: In some general aspects, a surface of a structure within a chamber of an extreme ultraviolet (EUV) light source is cleaned using a method. The method includes generating a plasma state of a material that is present at a location adjacent to a non-electrically conductive body that is within the chamber. The generation of the plasma state of the material includes electromagnetically inducing an electric current at the location adjacent the non-electrically conductive body to thereby transform the material that is adjacent the non-electrically conductive body from a first state into the plasma state. The plasma state of the material includes plasma particles, at least some of which are free radicals of the material. The method also includes enabling the plasma particles to pass over the structure surface to remove debris from the structure surface without removing the structure from the chamber of the EUV light source.

Abstract: The present disclosure introduces systems and related methods. Each system includes a first water electrolysis subsystem and a second water electrolysis subsystem. The first water electrolysis subsystem electrolyzes water to produce hydrogen and waste thermal energy. The second water electrolysis subsystem electrolyzes water to produce hydrogen utilizing the waste thermal energy produced by the first water electrolysis subsystem.

Abstract: A technique generates estimated time-of-arrival (ETA) information to assist in navigating from one physical location to another. The technique uses a computer-implemented route-finding engine to identify a route between a specified starting location and an ending location of a trip. The route includes a sequence of segments. The technique then uses a machine-trained model to map information regarding the segments to ETA information. The ETA information provides an estimate of a time-of-arrival for the trip as a whole. The ETA information also provides an estimate of parameters that describe the level of confidence of the time-of-arrival estimate for the trip. A training system produces the machine-trained model using a loss function, part of which models the time-of-arrival for the trip as a mixture of distributions.

Abstract: A radiation shield assembly is described, configured to block radiation emanating from a radiation source from reaching a user. Two shields are supported by a support arm, and are configured to rotate and translate relative to one another about the support arm's longitudinal axis. This allows the shield to be easily configured and reconfigured as necessary to visualize various parts of a patient's body via radiography.

Abstract: There are disclosed certain substituted pyrazine-2-carboxamides of Formula (I), and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are inhibitors of hematopoietic progenitor kinase 1 (HPK1) and are thereby particularly useful in the treatment or prophylaxis of cancer.

Abstract: A system for monitoring and optimizing fuel consumption by a genset at an oil rig is described. Gensets require large amounts of fuel to initiate and to maintain in a standby, idling position. The system accesses data in a drill plan to determine the present and future power requirements and initiates gensets if needed; otherwise gensets can be shut down. Excess power can be stored in a power storage unit such as a capacitor, battery, or a liquid air energy storage unit.

Abstract: A magnetic traction assembly is disclosed for a railcar mover that provides additional downforce to improve traction for a railcar mover when required. The magnetic traction assembly may comprise a frame, an actuator, and a magnetic element positioned underneath a railcar mover. The magnetic element may be lowered to a deployed position, where the magnetic element is positioned near the railroad rails such that the magnetic field from the magnetic element interacts with the railroad rail creating an attraction force that provides additional downforce to the railcar mover.

Abstract: Described herein are technologies related to generating a predicted routine of a user of a mobile computing device. Location entries generated by the mobile computing device are processed to generate visit entries, wherein the visit entries are representative of visits made by the user to places over several days. An input sequence of states is constructed based upon the visit entries, wherein each state has a place identifier assigned thereto, and further wherein each state corresponds to a time interval of predefined length. A predicted routine of the user is generated based upon the input sequence of states.

Abstract: The present disclosure presents a system and methodology for cryptocurrency trading. The system comprises a home-based trading machine, one or more servers and at least one database, each of which communicating via a network. The home-based trading machine is configured to encrypt at least one set of API credentials accessible to at least one currency exchange application in an encrypted packet; receive, from an electronic processing device operable by a vendor of the encrypted packet, the encrypted packet; implement the encryption key to decrypt the API key and the API secret key to unlock the encrypted packet to perform a cryptocurrency trade; and upon completion of the cryptocurrency trade, re-encrypt the API credentials.

Abstract: Systems and methods for controlling an autonomous vehicle are provided. In one example embodiment, a computer-implemented method includes determining vehicle diagnostics information associated with a first autonomous vehicle that is part of a fleet of vehicles controlled by a first entity to provide a vehicle service to a second entity. The method includes determining remote inspection information that includes an assessment of one or more categories pertaining to a third entity, based at least in part on the vehicle diagnostics information. The method includes providing the remote inspection information to the third entity to provide the vehicle service.

Abstract: A cutting element assembly includes a cutter support including a cutter bore. A cutting element is in the cutter bore and a resilient element is integral with the cutter support. The resilient element is longitudinally compressible and has a displacement of greater than 0.1 mm and optionally less than 2 mm. Another cutting assembly includes a cutter support coupled to multiple cutting elements. A resilient element of the cutter support is compressible based on a force applied to the cutter support through one or more of the cutting elements. The resilient element can include a slit in the cutter support. A slit may, for instance, extend perpendicular or transverse to an axis of the cutting elements and allow the cutter support to flex and close off or reduce a size of the slit when forces act on one or more of the cutting elements.

Abstract: The specification relates to compounds of Formula (1): and to pharmaceutically acceptable salts thereof, to processes and intermediates used for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of cancer.

Abstract: A system for monitoring and optimizing fuel consumption by a genset at an oil rig is described. Gensets require large amounts of fuel to initiate and to maintain in a standby, idling position. The system accesses data in a drill plan to determine the present and future power requirements and initiates gensets if needed; otherwise gensets can be shut down. Excess power can be stored in a power storage unit such as a capacitor, battery, or a liquid air energy storage unit.