Patents by Inventor Robert F. Leveen

Robert F. Leveen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6575967
    Abstract: A volumetric tissue ablation apparatus includes a probe having a plurality of wires journaled through a catheter with a proximal end connected to the active terminal of a generator and a distal end projecting from a distal end of the catheter. The probe wire distal ends are arranged in an array with the distal ends located generally radially and uniformly spaced-apart from the catheter distal end. A conductor connected to the return terminal of the generator is located relative to the probe wire array to form a closed electrical circuit through tissue to be ablated. Preferably, the probe wire array includes 10 wires, each formed in an arch from the catheter distal end. The conductor can be either a conventional ground plate upon which the tissue is supported, or a conductor wire extending through the probe and electrically insulated from the probe wires.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: June 10, 2003
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Robert F. Leveen, Randy Fox
  • Patent number: 6468273
    Abstract: A volumetric tissue ablation apparatus includes a probe having a plurality of wires journaled through a catheter with a proximal end connected to the active terminal of a generator and a distal end projecting from a distal end of the catheter. The probe wire distal ends are arranged in an array with the distal ends located generally radially and uniformly spaced-apart from the catheter distal end. A conductor connected to the return terminal of the generator is located relative to the probe wire array to form a closed electrical circuit through tissue to be ablated. Preferably, the probe wire array includes 10 wires, each formed in an arch from the catheter distal end. The conductor can be either a conventional ground plate upon which the tissue is supported, or a conductor wire extending through the probe and electrically insulated from the probe wires.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: October 22, 2002
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Robert F. Leveen, Randy Fox
  • Patent number: 6454765
    Abstract: A volumetric tissue ablation apparatus includes a probe having a plurality of wires journaled through a catheter with a proximal end connected to the active terminal of a generator and a distal end projecting from a distal end of the catheter. The probe wire distal ends are arranged in an array with the distal ends located generally radially and uniformly spaced-apart from the catheter distal end. A conductor connected to the return terminal of the generator is located relative to the probe wire array to form a closed electrical circuit through tissue to be ablated. Preferably, the probe wire array includes 10 wires, each formed in an arch from the catheter distal end. The conductor can be either a conventional ground plate upon which the tissue is supported, or a conductor wire extending through the probe and electrically insulated from the probe wires.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: September 24, 2002
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Robert F. Leveen, Randy Fox
  • Patent number: 5868740
    Abstract: A volumetric tissue ablation apparatus includes a probe having a plurality of wires journaled through a catheter with a proximal end connected to the active terminal of a generator and a distal end projecting from a distal end of the catheter. The probe wire distal ends are arranged in an array with the distal ends located generally radially and uniformly spaced apart from the catheter distal end. A conductor connected to the return terminal of the generator is located relative to the probe wire array to form a closed electrical circuit through tissue to be ablated. Preferably, the probe wire array includes 10 wires, each formed in an arch from the catheter distal end. The conductor can be either a conventional ground plate upon which the tissue is supported, or a conductor wire extending through the probe and electrically insulated from the probe wires.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: February 9, 1999
    Assignee: Board of Regents-Univ of Nebraska
    Inventors: Robert F. LeVeen, Randy Fox
  • Patent number: 5855576
    Abstract: A volumetric tissue ablation apparatus includes a probe having a plurality of wires journaled through a catheter with a proximal end connected to the active terminal of a generator and a distal end projecting from a distal end of the catheter. The probe wire distal ends are arranged in an array with the distal ends located generally radially and uniformly spaced apart from the catheter distal end. A conductor connected to the return terminal of the generator is located relative to the probe wire array to form a closed electrical circuit through tissue to be ablated. Preferably, the probe wire array includes 10 wires, each formed in an arch from the catheter distal end. The conductor can be either a conventional ground plate upon which the tissue is supported, or a conductor wire extending through the probe and electrically insulated from the probe wires.
    Type: Grant
    Filed: December 12, 1996
    Date of Patent: January 5, 1999
    Assignee: Board of Regents of University of Nebraska
    Inventors: Robert F. LeVeen, Randy Fox
  • Patent number: 5827276
    Abstract: A volumetric tissue ablation apparatus includes a probe having a plurality of wires journaled through a catheter with a proximal end connected to the active terminal of a generator and a distal end projecting from a distal end of the catheter. The probe wire distal ends are arranged in an array with the distal ends located generally radially and uniformly spaced apart from the catheter distal end. A conductor connected to the return terminal of the generator is located relative to the probe wire array to form a closed electrical circuit through tissue to be ablated. Preferably, the probe wire array includes 10 wires, each formed in an arch from the catheter distal end. The conductor can be either a conventional ground plate upon which the tissue is supported, or a conductor wire extending through the probe and electrically insulated from the probe wires.
    Type: Grant
    Filed: December 12, 1996
    Date of Patent: October 27, 1998
    Assignee: Board of Regents of Univ of Nebraksa
    Inventors: Robert F. LeVeen, Randy Fox
  • Patent number: 5810755
    Abstract: A wound dressing, suitable for use in protecting an open wound or burned tissue from direct exposure to air and capable of maintaining an aqueous environment of wounded tissue with which it is in brought into contact is comprised of a hydrophilic, yet insoluble material, advantageously a polymeric compound capable of being reversibly complexed with elemental iodine, thereby permitting release of therapeutic amounts of free iodine into a wound with which it is brought in contact. As a shaped mass of pliable and absorbent material, such a polymeric foam, such dressing is particularly suited for application to fresh and infected burns and open wounds. When alternatively configured as a hydrophilic film complexed with free iodine for use as a surgical drape, in addition to providing a barrier against direct exposure to air, such dressing is bacteriocidal, preventing infection of the wound from airborne contaminants in the operating room.
    Type: Grant
    Filed: September 12, 1996
    Date of Patent: September 22, 1998
    Inventors: Harry H. LeVeen, Mary Louise LeVeen, Eric G. LeVeen, Robert F. LeVeen
  • Patent number: 5698214
    Abstract: Monilial Vulvovaginitis is treated by application of a composition containing one or more substances which inhibit glucose transfer into cells and cell metabolism. The composition of the invention is conveniently combined with a suitable carrier such as a non-aqueous gel and other therapeutically useful components.
    Type: Grant
    Filed: February 24, 1992
    Date of Patent: December 16, 1997
    Inventors: Harry H. Leveen, Eric G. Leveen, Robert F. Leveen
  • Patent number: 5573547
    Abstract: A method of fixation for use within animal and human bodies provides for the insertion of brushes, of cylindrical and conical designs, into openings wherein bristles of the brushes are deflected by walls of the openings such that the brushes are locked in place and resist forces applied thereto. An embodiment of the invention includes boring a hole into a cancellous bone structure and inserting a brush into the hole. The hole is of a smaller diameter than the brush and is locked in the hole by the bristles. Tissue, such as tendon, may then be attached to material affixed to an end of the brush. Another embodiment of the method includes insertion of a brush into a blood vessel such that the blood flow is either occluded or strained by the bristles of the brush.
    Type: Grant
    Filed: October 19, 1993
    Date of Patent: November 12, 1996
    Inventors: Harry H. LeVeen, Eric G. LeVeen, Robert F. LeVeen
  • Patent number: 5520632
    Abstract: A device for the transfer of body fluids which accumulate in the peritoneum cavity into the vascular system comprising a peritoneal tube connected to the inlet chamber of a hollow plastic implanted valve assembly, causing a valve to open and passing the fluid under pressure into a second reservoir from where the fluid is conducted through a venous tubing which is connected to the jugular vein of the patient. The valve assembly comprises a plastic housing with an inlet and outlet, the peritoneal tube being secured to the inlet leading to an inlet reservoir located within the valve housing and the venous tube being secured to the outlet leading from the outlet reservoir located within the valve housing.
    Type: Grant
    Filed: April 11, 1991
    Date of Patent: May 28, 1996
    Assignee: Robert Leveen
    Inventors: Robert F. Leveen, Eric G. Leveen
  • Patent number: 5388449
    Abstract: An osmolarity sensor continuously senses an osmolarity of a fluid. A principle of operation is based on achieving an equilibrium of a vapor pressure of a specimen solution with a vapor pressure of a standard solution. In an embodiment, the standard solution is contained in a cavity defined by a vapor-permeable membrane which is immersed in a specimen solution. The standard solution and the specimen solution are allowed to come into equilibrium by a movement of water vapor across the vapor-permeable membrane, which is permeable only to water vapor and not to any solutes or water itself. The movement of the water vapor between the standard solution and the specimen is measured by sensing a volume of water transferred between the standard solution and the specimen solution. A measurement of a volume change of the standard solution is made by sensing a change a conductivity of the standard solution.
    Type: Grant
    Filed: July 6, 1993
    Date of Patent: February 14, 1995
    Inventors: Harry H. LeVeen, Eric G. LeVeen, Robert F. LeVeen
  • Patent number: 5156164
    Abstract: A bacteriocidal virocidal sponge containing iodine and a surfactant which can be used as a contraceptive and as therapy for vaginitis. It consists of a polyurethane open cell foam impregnated with a surfactant and iodine. A bactericidal tampon containing an iodophor does not induce toxic shock syndrome.
    Type: Grant
    Filed: February 4, 1991
    Date of Patent: October 20, 1992
    Inventors: Harry H. LeVeen, Robert F. LeVeen
  • Patent number: 5128147
    Abstract: A sterile injectable mixture which intensifies and localizes radio frequency thermotherapy; the injectable mixture contains finely ground ferrite particles in a viscid aqueous suspension, the ferrite being matched for maximum radio frequency absorption at a specific frequency. A chemotherapeutic agent, a surfactant and a bioacceptable hydrophic colloid are also contained in the mixture.
    Type: Grant
    Filed: August 6, 1990
    Date of Patent: July 7, 1992
    Assignee: Thermal Developments, Inc.
    Inventors: Harry H. Leveen, Eric G. Leveen, Robert F. Leveen
  • Patent number: 5123909
    Abstract: A device for cracking plaque from a blood vessel comprising a fixed jaw member assembly, a moveable jaw member and hammer assembly slidably mounted on the fixed jaw member assembly and a spring transmitting a driving force to the hammer assembly. A handle is connected to the fixed jaw member assembly and a trigger activation assembly is mounted in the handle to activate a trigger releasing the hammer assembly to transmit a driving force against the moveable jaw member and an adjacent blood vessel.
    Type: Grant
    Filed: May 21, 1990
    Date of Patent: June 23, 1992
    Inventors: Harry H. LeVeen, Robert F. LeVeen, Eric G. LeVeen
  • Patent number: 5110801
    Abstract: Acne is treated by administering to the subject a substance which is effective in blocking glucose entry into sebaceous cells, thereby inhibiting the production of sebum by these cells. Typically, the substance is administered topically and is dissolved or suspended in an appropriate solvent. The preferred substance is phloretin, which can for example, be dissolved in propylene glycol.
    Type: Grant
    Filed: February 22, 1989
    Date of Patent: May 5, 1992
    Inventors: Harry H. Leveen, Robert F. Leveen
  • Patent number: 5070889
    Abstract: A bacteriocidal virocidal sponge containing iodine and/or chlorhexidine and a surfactant which can be used as a contraceptive and virocidal and bacteriocidal sponge positioned within a human body comprising a polyurethane open cell foam impregnated with a surfactant and iodine and/or chlorhexidine. A bactericidal tampon containing an iodophor or chlorhexidine does not induce toxic shock syndrome.
    Type: Grant
    Filed: November 15, 1990
    Date of Patent: December 10, 1991
    Inventors: Harry H. Leveen, Robert F. Leveen, Eric G. Leveen
  • Patent number: 5000749
    Abstract: A bacteriocidal virocidal sponge containing iodine and a surfactant which can be used as a contraceptive and as therapy for vaginitis. It consists of a polyurethane open cell foam impregnated with a surfactant and iodine. A bactericidal tampon containing an iodophor does not induce toxic shock syndrome.
    Type: Grant
    Filed: March 2, 1989
    Date of Patent: March 19, 1991
    Inventors: Harry H. LeVeen, Eric G. LeVeen, Robert F. LeVeen
  • Patent number: 5000750
    Abstract: A medical apparatus for the removal of stool comprising an auger assembly, a helical auger and a hand crank connected to said auger to apply torque to the auger rotatably mounted in a cylindrical connecter housing. A bayonet lock mounted to said connecter housing is adapted to lock and hold a rectal insertion tube in a fixed position. The rectal insertion tube comprising a tube body having a diameter greater than the helix of the auger and has a handle at one end extending therefrom, the other end of the tube body being adapted to be inserted into a rectal ampulla.
    Type: Grant
    Filed: December 14, 1988
    Date of Patent: March 19, 1991
    Assignee: Device Developments, Inc.
    Inventors: Robert F. LeVeen, Eric G. LeVeen
  • Patent number: 4988355
    Abstract: A surgical clamp comprising a pair of arms, each arm being interconnected at one end to one end of the other arm by a flexible, resilient member normally urging said arms apart while maintaining facing surfaces. A clamping strip of resilient material is mounted on the arms, the resilient material being softer than the material of the clamping arms. A releasable ratchet assembly including a ratchet body and flexible tubing is positioned on the opposite end of one of the arms extending toward and being engageable with a holding lip on the other arm, so that when the arms are moved toward each other, the arms can be held in fixed relative positions, mounted to said body.
    Type: Grant
    Filed: January 16, 1990
    Date of Patent: January 29, 1991
    Inventors: Eric G. Leveen, Robert F. Leveen
  • Patent number: 4968439
    Abstract: A canteen containing an iodine polyurethane complex open cell foam sponge for sterilization of water contained in the canteen.
    Type: Grant
    Filed: October 13, 1988
    Date of Patent: November 6, 1990
    Assignee: Medicinal Developments, Inc.
    Inventors: Harry H. Leveen, Eric G. Leveen, Robert F. LeVeen