Patents by Inventor Robert F. Rosenbluth

Robert F. Rosenbluth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7483558
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: January 27, 2009
    Assignee: MicroVention, Inc.
    Inventors: George R. Greene, Jr., Robert F. Rosenbluth, Brian J. Cox
  • Publication number: 20080223367
    Abstract: Methods and Devices for treating airway openings and breathing disorders including obstructive sleep apnea are disclosed. Structures and methods disclosed herein maintain and preserve airway openings against posterior collapse of the tongue.
    Type: Application
    Filed: January 29, 2008
    Publication date: September 18, 2008
    Inventors: Brian J. Cox, Robert F. Rosenbluth, Dean Schaefer
  • Patent number: 7201762
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Grant
    Filed: December 16, 2002
    Date of Patent: April 10, 2007
    Assignee: Microvention, Inc.
    Inventors: George R. Greene, Jr., Robert F. Rosenbluth, Brian J. Cox
  • Patent number: 7033374
    Abstract: A vaso-occlusive device includes a microcoil formed into a minimum energy state secondary configuration comprising a plurality of curved segments, each defining a discrete axis, whereby the device, in its minimum energy state configuration, defines multiple axes. In a preferred embodiment, the secondary configuration-comprises a plurality of interconnected closed loops defining a plurality of discrete axes. In a second embodiment, the secondary configuration defines a wave-form like structure comprising an array of laterally-alternating open loops defining a plurality of separate axes. In a third embodiment, the secondary configuration forms a series of tangential closed loops, wherein the entire structure subtends a first angle of arc, and wherein each adjacent pair of loops defines a second angle of arc. In a fourth embodiment, the secondary configuration forms a logarithmic spiral.
    Type: Grant
    Filed: January 11, 2002
    Date of Patent: April 25, 2006
    Assignee: Microvention, Inc.
    Inventors: Dean Schaefer, Brian J. Cox, George R. Greene, Jr., David A. Ferrera, Matthew Fitz, Robert F. Rosenbluth
  • Patent number: 7029487
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: April 18, 2006
    Assignee: Microvention, Inc.
    Inventors: George R. Greene, Jr., Robert F. Rosenbluth, Brian J. Cox
  • Patent number: 7029486
    Abstract: A microcoil vaso-occlusive device has a minimum energy state secondary configuration having a plurality of curved segments, each defining a discrete axis. The secondary configuration may be a plurality of interconnected closed loops; an array of laterally-alternating open loops; a series of tangential closed loops; or a logarithmic spiral. The device, in its secondary cofiguration, has a dimension that is substantially larger than the largest dimension of the vascular site in which it is to be deployed. Thus, confinement of the device within the site causes it to assume a configuration with a higher energy state than the minimum energy state. Because the secondary configuration is larger (in at least one dimension) than the site, the device is constrained, by contact with the walls of the site, from returning to its secondary configuration, and shifting of the device due to blood flow is minimized.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: April 18, 2006
    Assignee: Microvention, Inc.
    Inventors: Dean Schaefer, Brian J. Cox, George R. Greene, Jr., David A. Ferrera, Matthew Fitz, Robert F. Rosenbluth
  • Publication number: 20040133232
    Abstract: Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing clots or other obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable with or over a guidewire which has been pre-inserted through or around the clot. Also, in some embodiments, the embolectomy catheters include clot removal devices which are deployable from the catheter after the catheter has been advanced at least partially through the clot. The clot removal device may include a deployable wire nest that is designed to prevent a blood clot from passing therethrough.
    Type: Application
    Filed: December 9, 2003
    Publication date: July 8, 2004
    Applicant: MicroVention, Inc.
    Inventors: Robert F. Rosenbluth, George R. Green, Brian J. Cox, Thomas R. Sternweiler, Sean L. Chow, Richard R. Monetti
  • Patent number: 6689141
    Abstract: A mechanism for the deployment of a filamentous endovascular device includes a flexible deployment tube having an open proximal end, and a coupling element attached to the proximal end of the endovascular device. The deployment tube includes a distal section terminating in an open distal end, with a lumen defined between the proximal and distal ends. A retention sleeve is fixed around the distal section and includes a distal extension extending a short distance past the distal end of the deployment tube. The endovascular device is attached to the distal end of the deployment tube by fixing the retention sleeve around the coupling element, so that the coupling element is releasably held within the distal extension of the deployment tube. In use, the deployment tube, with the implant attached to its distal end, is passed intravascularly through a microcatheter to a target vascular site until the endovascular device is located within the site.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: February 10, 2004
    Assignee: MicroVention, Inc.
    Inventors: David A. Ferrera, George R. Greene, Jr., Brian J. Cox, Robert F. Rosenbluth
  • Patent number: 6685722
    Abstract: Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing clots or other obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable with or over a guidewire which has been pre-inserted through or around the clot. Also, in some embodiments, the embolectomy catheters include clot removal devices which are deployable from the catheter after the catheter has been advanced at least partially through the clot. The clot removal device may include a deployable wire nest that is designed to prevent a blood clot from passing therethrough.
    Type: Grant
    Filed: November 10, 1999
    Date of Patent: February 3, 2004
    Assignee: MicroVention, Inc.
    Inventors: Robert F. Rosenbluth, George R. Green, Jr., Brian J. Cox, Thomas R. Sternweiler, Sean L. Chow, Richard R. Monetti
  • Patent number: 6607538
    Abstract: A mechanism for the deployment of an endovascular device having a coupling element attached to its proximal end, includes a deployment tube having a proximal end, a distal section, open distal end, and a lumen extending between the proximal and distal ends. A retention sleeve, fixed around the distal section, includes an extension extending past the distal end of the tube. The retention sleeve is fixed around the coupling element, so that the coupling element is releasably held within the extension. In use, the deployment tube, with the implant attached to its distal end, is passed intravascularly until the device is deployed within a target site. A liquid is injected through the lumen so as to push the coupling element out of the retention sleeve by fluid pressure, thereby detaching the endovascular device from the deployment tube.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: August 19, 2003
    Assignee: Microvention, Inc.
    Inventors: David A. Ferrera, George R. Greene, Jr., Brian J. Cox, Robert F. Rosenbluth
  • Publication number: 20030088311
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Application
    Filed: December 16, 2002
    Publication date: May 8, 2003
    Inventors: George R. Greene, Robert F. Rosenbluth, Brian J. Cox
  • Publication number: 20030083737
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Application
    Filed: December 4, 2002
    Publication date: May 1, 2003
    Inventors: George R. Greene, Robert F. Rosenbluth, Brian J. Cox
  • Patent number: 6511492
    Abstract: Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherschlerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable over a guidewire which has been pre-inserted through or around the obstructive matter. Also, in some embodiments, the embolectomy catheters include obstructive matter capturing receptacles which are deployable from the catheter after the catheter has been advanced at least partially through the obstructive matter.
    Type: Grant
    Filed: May 1, 1998
    Date of Patent: January 28, 2003
    Assignee: MicroVention, Inc.
    Inventors: Robert F. Rosenbluth, Brian J. Cox, George R. Greene, Jr.
  • Publication number: 20030018356
    Abstract: A vaso-occlusive device includes a microcoil formed into a minimum energy state secondary configuration comprising a plurality of curved segments, each defining a discrete axis, whereby the device, in its minimum energy state configuration, defines multiple axes. In a preferred embodiment, the secondary configuration comprises a plurality of interconnected closed loops defining a plurality of discrete axes. In a second embodiment, the secondary configuration defines a wave-form like structure comprising an array of laterally-alternating open loops defining a plurality of separate axes. In a third embodiment, the secondary configuration forms a series of tangential closed loops, wherein the entire structure subtends a first angle of arc, and wherein each adjacent pair of loops defines a second angle of arc. In a fourth embodiment, the secondary configuration forms a logarithmic spiral.
    Type: Application
    Filed: September 19, 2002
    Publication date: January 23, 2003
    Inventors: Dean Schaefer, Brian J. Cox, George R. Greene, David A. Ferrera, Matthew Fitz, Robert F. Rosenbluth
  • Publication number: 20030014075
    Abstract: Methods and apparatus for treating or preventing endoleaks after an endovascular graft (e.g., a stent, tubular graft, stent-graft, coated stent, covered stent, intravascular flow modifier or other endovascular implant that affects, limits or prevents blood flow into a vascular defect such as an aneurysm, arterio-venous fistula, arterio-venous malformation, vessel wall perforation, etc.) has been implanted in the vasculature of a human or veterinary patient. An expansile polymeric material, such as a swellable polymer (e.g., a hydrogel), a flexible or elastomeric polymer foam (e.g. silicone, polyurethane, etc.) or a carrier member (e.g, a coil, filament, wire, etc) that carries a quantity of such expansile polymer is delivered into a perigraft space (i.e., space between the endovascular graft and the surrounding blood vessel wall) such that the polymeric material expands in situ to substantially fill the perigraft space or a portion thereof.
    Type: Application
    Filed: July 16, 2001
    Publication date: January 16, 2003
    Applicant: MicroVention, Inc.
    Inventors: Robert F. Rosenbluth, Brian J. Cox, Jay A. Lenker
  • Patent number: 6500190
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embodied. Preferably, the implant is formed of a hydrophobic, macro porous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolism a vascular site, the implant is compressed and passed through a micro catheter, the distal end of which has been passed into a vascular site.
    Type: Grant
    Filed: December 5, 2000
    Date of Patent: December 31, 2002
    Assignee: MicroVention
    Inventors: George R. Greene, Jr., Robert F. Rosenbluth, Brian J. Cox
  • Publication number: 20020188311
    Abstract: A mechanism for the deployment of a filamentous endovascular device includes a flexible deployment tube having an open proximal end, and a coupling element attached to the proximal end of the endovascular device. The deployment tube includes a distal section terminating in an open distal end, with a lumen defined between the proximal and distal ends. A retention sleeve is fixed around the distal section and includes a distal extension extending a short distance past the distal end of the deployment tube. The endovascular device is attached to the distal end of the deployment tube by fixing the retention sleeve around the coupling element, so that the coupling element is releasably held within the distal extension of the deployment tube. In use, the deployment tube, with the implant attached to its distal end, is passed intravascularly through a microcatheter to a target vascular site until the endovascular device is located within the site.
    Type: Application
    Filed: May 10, 2002
    Publication date: December 12, 2002
    Inventors: David A. Ferrera, George R. Greene, Brian J. Cox, Robert F. Rosenbluth
  • Publication number: 20020107534
    Abstract: A vaso-occlusive device includes a microcoil formed into a minimum energy state secondary configuration comprising a plurality of curved segments, each defining a discrete axis, whereby the device, in its minimum energy state configuration, defines multiple axes. In a preferred embodiment, the secondary configuration-comprises a plurality of interconnected closed loops defining a plurality of discrete axes. In a second embodiment, the secondary configuration defines a wave-form like structure comprising an array of laterally-alternating open loops defining a plurality of separate axes. In a third embodiment, the secondary configuration forms a series of tangential closed loops, wherein the entire structure subtends a first angle of arc, and wherein each adjacent pair of loops defines a second angle of arc. In a fourth embodiment, the secondary configuration forms a logarithmic spiral.
    Type: Application
    Filed: January 11, 2002
    Publication date: August 8, 2002
    Inventors: Dean Schaefer, Brian J. Cox, George R. Greene, David A. Ferrera, Matthew Fitz, Robert F. Rosenbluth
  • Patent number: 6375669
    Abstract: Apparatus for vascular embolization, deployable through a microcatheter, includes a flexible, elongate deployment tube dimensioned for insertion through the microcatheter, and a filamentous embolic device releasably attached to the distal end of the tube. The embolic device is controllably transformable from a soft, compliant state to a rigid or semi-rigid state. The embolic device may include a polymeric material that is transformable by contact with vascular blood or with a liquid that is cooler than vascular blood, or it may include a metallic material that is transformable by electrolytic corrosion. The embolic device may be a continuous filamentous polymeric extrusion; an elongate microcoil filled with polymeric material; an elongate, multi-segmented chain including polymeric interconnecting portions; or an elongate chain of metal segments that are fused together by electrolytic corrosion.
    Type: Grant
    Filed: December 23, 1999
    Date of Patent: April 23, 2002
    Assignee: MicroVention, Inc.
    Inventors: Robert F. Rosenbluth, Brian J. Cox, George R. Green, Jr.
  • Patent number: 6299619
    Abstract: An embolization device includes a plurality of highly-expansible embolizing elements disposed at spaced intervals along a filamentous carrier. In a preferred embodiment, the carrier is a suitable length of very thin, highly flexible filament of nickel/titanium alloy. The embolizing elements are separated from each other on the carrier by radiopaque spacers in the form of highly flexible microcoils made of platinum or platinum/tungsten alloy. In a preferred embodiment, the embolizing elements are made of a hydrophilic, macroporous, polymeric, hydrogen foam material. The device is particularly suited for embolizing a vascular site such as an aneurysm. The embolization bodies have an initial configuration in the form of small, substantially cylindrical “micropellets” of small enough outside diameter to fit within a microcatheter. The bodies are hydrophilically expansible into an expanded configuration in which they substantially conform to and fill the vascular site while connected to the carrier.
    Type: Grant
    Filed: April 4, 2000
    Date of Patent: October 9, 2001
    Assignee: MicroVention, Inc.
    Inventors: George R. Greene, Jr., Robert F. Rosenbluth, Brian J. Cox