Abstract: Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are commonly used to assess patients with known or suspected pathologies of the lungs and liver. In particular, identification and quantification of possibly malignant regions identified in these high-resolution images is essential for accurate and timely diagnosis. However, careful quantitative assessment of lung and liver lesions is tedious and time consuming. This disclosure describes an automated end-to-end pipeline for accurate lesion detection and segmentation.

Abstract: Apparatus and method for treating a substrate, for example texturing a substrate. In some embodiments, a masking material is applied to a surface of the substrate in a predetermined pattern, the surface thereafter contacted with an etchant that removes the masking material. Contacting the surface with the etchant produces multiple co-located textures. In other embodiments, the masking step can be eliminated, and the etchant is applied in a predetermined pattern to produce multiple co-located textures. In still other embodiments, the substrate has a chemical composition, and the substrate is exposed to a leachant that leaches at least one constituent of the chemical composition to produce a substrate with a varying chemical composition at the substrate surface.

Abstract: An improvement to an air operated double diaphragm pump may include ball guides to restrain movement of balls relative to suction and delivery seats to substantially linear travel, as opposed to the prior art three-dimensional travel. The guides may have curved surfaces to reduce wear on balls over prior art designs. The pumps may have supports and an intake manifold whereby the intake manifold may be removed to access the intake balls and intake ball valve seals without requiring the pump to be completely removed from an installation as is required with prior art designs.

Abstract: This invention relates to compositions that include a polypeptide derived from E. coli or a fragment thereof; and modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof, and methods of use thereof.

Abstract: Connected computing enables the use of highly diverse environments that support operating frameworks for contemporary civilization. But computing productivity and trustworthiness are undermined by such environments' largely inchoate organization. These environments and their identity infrastructures are fragmented, and unnecessarily unreliable, insecure, and insufficiently informative due to current computing entity (e.g., resource) identification infrastructure design, which lacks root identification reliability. Such reliability is enabled herein by a fundamentally accurate and authenticity ensuring, near-existential or existential quality, biometrically and liveness based, portable identification and provenance infrastructure. Such an infrastructure provides ubiquitously available identification information that can be used universally for identification processes.

Abstract: An airplane door sill protector is provided. The sill protector is used to fit to a sill and fuselage of an airplane to prevent damage to the fuselage. The sill protector includes an elongated body having a base joined with a lip that forms a channel to receive the fuselage of the airplane door. A first and second curved section are positioned at opposing ends of the elongated body, such that each curved section arches away from a longitudinal axis and can accommodate a curved exterior edge of the airplane fuselage. The curved sections correspond to the curve of the fuselage and, in some embodiments, are extendable to fit openings of various sizes.

Abstract: Provided herein are recombinant antibodies and antigen-binding fragments thereof useful for binding to and inhibiting carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1). Also provided are methods of using the disclosed CEACAM1 antibodies and antigen-binding fragments thereof for reducing T-cell tolerance and for the treatment of cancer.

Abstract: A thin-film transistor (TFT), includes: a substrate (202); an organic semiconductor (OSC) layer (210) positioned on the substrate; a dielectric layer (214) positioned on the OSC layer; and a polymeric interlayer (212) disposed in-between the OSC layer and the dielectric layer, such that the dielectric layer is configured to exhibit a double layer capacitance effect. A method of forming a thin-film transistor, includes: providing a substrate; providing a bottom gate layer atop the substrate; disposing consecutively from the substrate, an organic semiconductor (OSC) layer, a dielectric layer, and a top gate layer; and patterning the OSC layer, the dielectric layer, and the top gate layer using a single mask.

Abstract: A modular toy system comprising a plurality of separate electronic toy modules, each electronic toy module comprising a function device operable to perform a user-perceptible function and a control circuit for controlling the function device; wherein at least a first electronic toy module of the plurality of electronic toy modules comprises a first control circuit, a first function device and a sensor system configured for contactless detection of respective coordinate values of at least two coordinates, each coordinate being indicative of a position or an orientation of at least a second electronic toy module of the plurality of electronic toy modules relative to the first electronic toy module; and wherein the first control circuit is configured to control operation of the first function device based on one or more of the detected coordinate values.

Abstract: The invention relates to RNA molecules encoding an E. coli fimbrial H antigen (FimH). The present disclosure further relates to compositions comprising the RNA molecules formulated in a lipid nanoparticle (RNA-LNP). The present disclosure further relates to the use of the RNA molecules, RNA-LNPs and compositions for the prevention of E. coli infection, including urinary tract infection.

Abstract: A composite includes a substrate and a target material, wherein the target material includes indium oxide (In2O3), tin oxide (SnO2), and gallium oxide (Ga2O3), and a method for making the same. The method includes positioning the substrate and a target in a chamber and applying radio frequency (RF) power to the chamber to sputter ions of target material from the target onto the substrate.

Abstract: Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are commonly used to assess patients with known or suspected pathologies of the lungs and liver. In particular, identification and quantification of possibly malignant regions identified in these high-resolution images is essential for accurate and timely diagnosis. However, careful quantitative assessment of lung and liver lesions is tedious and time consuming. This disclosure describes an automated end-to-end pipeline for accurate lesion detection and segmentation.

Abstract: Embodiments herein generally relate to methods, systems and devices for automated assembly of building structures. In at least one embodiment, there is provided a robotic assembly cell for assembling building structures. The robotic assembly cell comprises a perception sensor system; one or more assembly robots; and at least one processor operable to: receive instructions corresponding to an assembly sequence for assembling a building structure; determine a plurality of building parts required for assembling the building structure based on the assembly sequence; identify each building part within a facility, based on sensor data from the perception sensor system; configure the assembly robot to retrieve the target pieces; and configure the assembly robot to assemble the target pieces according to the assembly sequence.

Abstract: Provided herein are recombinant antibodies and antigen-binding fragments thereof useful for binding to and inhibiting carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1). Also provided are methods of using the disclosed CEACAM1 antibodies and antigen-binding fragments thereof for reducing T-cell tolerance and for the treatment of cancer.

Abstract: One aspect of the invention relates to a method comprising a single-stage conversion of an atmospheric pollutant, such as NO, NO2 and/or SOx in a first stream to one or more mineral acids and/or salts thereof by reacting with nonionic gas phase chlorine dioxide (ClO20 ), wherein the reaction is carried out in the gas phase. Another aspect of the invention relates to a method comprising first adjusting the atmospheric pollutant concentrations in a first stream to a molar ratio of about 1:1, and then reacting with an aqueous metal hydroxide solution (MOH). Another aspect of the invention relates to an apparatus that can be used to carry out the methods disclosed herein. The methods disclosed herein are unexpectedly efficient and cost effective, and can be applied to a stream comprising high concentration and large volume of atmospheric pollutants.

Abstract: A system and method for applying a construction material is provided. The method may include mixing blast furnace slag material, geopolymer material, alkali-based powder, and sand at a mixing device to generate a non-Portland cement-based material. The method may also include transporting the non-Portland cement-based material from the mixing device, through a conduit to a nozzle and combining the transported non-Portland cement-based material with water at the nozzle to generate a partially liquefied non-Portland cement-based material. The method may further include pneumatically applying the partially liquefied non-Portland cement-based material to a surface.

Abstract: This invention relates to compositions that include a polypeptide derived from E. coli or a fragment thereof; and modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof, and methods of use thereof.

Abstract: A first image capture device is operative to capture images in a first direction, the first image capture device comprising a first coupling configured to receive a complementary coupling of a second image capture device; the first image capture device further comprising a housing, a portion of which comprises a recessed area in the surface of the housing of the first image capture device; a second image capture device removably coupleable to the first image capture device and operative to capture images in a second direction different to the first direction, the second image capture device comprising a second coupling; the second image capture device further comprising a housing, a portion of which comprises a lug extending from the surface of the housing, wherein the first and second couplings are configured to electro-mechanically couple the second image capture device to the first image capture device by complementary inter-engagement.

Abstract: A toy construction system comprising a plurality of toy construction elements including a plurality of function construction elements. The toy construction elements and the function construction elements are detachably interconnected with each other forming a toy construction model. The toy construction model comprising at least a subset of the plurality of toy construction elements; each function construction element comprising a function device adapted to perform a user-perceptible function. The toy construction system further comprises a tag construction element detachably connectable to one or more of the toy construction elements. The tag construction element and the function construction elements are configured for communication of configuration data from the tag construction element to each of the subset of function construction elements when the tag construction element is connected to a toy construction element.

Abstract: The present disclosure provides antibodies specific for an epitope present on CD22. The antibodies are useful in various treatment, diagnostic, and monitoring applications, which are also provided.