Patents by Inventor Robert J. Collier

Robert J. Collier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7081482
    Abstract: The invention is directed to the use of ?-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: July 25, 2006
    Assignee: Alcon, Inc.
    Inventors: Robert J. Collier, Jr., Louis Desantis, Jr., Michael A. Kapin
  • Publication number: 20040116402
    Abstract: The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Application
    Filed: December 5, 2003
    Publication date: June 17, 2004
    Inventors: Peter G. Klimko, Robert J. Collier, Mark R. Hellberg
  • Publication number: 20040116403
    Abstract: The use of SOD mimics, particularly Mn(III) porphyrin complexes, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Application
    Filed: December 5, 2003
    Publication date: June 17, 2004
    Inventors: Peter G. Klimko, Robert J. Collier, Mark R. Hellberg
  • Publication number: 20030207890
    Abstract: Compositions and methods for treating disorders of the outer retina with compounds with 5-HT1A against activity are disclosed.
    Type: Application
    Filed: September 9, 2002
    Publication date: November 6, 2003
    Inventors: Robert J Collier, Michael A Kapin, Mark R Hellberg, Thomas R Dean
  • Publication number: 20030119846
    Abstract: Compounds with 5-HT1A agonist activity which are useful for controlling the visual field loss associated with glaucoma are disclosed.
    Type: Application
    Filed: September 9, 2002
    Publication date: June 26, 2003
    Inventors: Robert J. Collier Jr, Mark R. Hellberg, Thomas R. Dean
  • Publication number: 20030114512
    Abstract: Compounds with both 5-HT2 and 5-HT1A agonist activity which are useful for lowering and controlling IOP and the treatment of glaucomatous optic neuropathy.
    Type: Application
    Filed: September 9, 2002
    Publication date: June 19, 2003
    Inventors: Robert J Collier, Thomas R Dean, Mark R Hellberg
  • Patent number: 6509355
    Abstract: This invention is directed to the use of glutamate antagonists to treat the disorders of outer retina.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: January 21, 2003
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert J. Collier, Jr., Mark R. Hellberg, Michael A. Kapin, George E. Barnes, Michael L. Chandler
  • Publication number: 20020193373
    Abstract: The invention is directed to the use of beta-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina.
    Type: Application
    Filed: May 15, 2002
    Publication date: December 19, 2002
    Inventors: Robert J. Collier, Jr., Louis Desantis, Jr., Michael A. Kapin
  • Patent number: 5719167
    Abstract: The present invention is directed to compositions containing angiostatic compounds and methods for their use in preventing pathological neovascularization.
    Type: Grant
    Filed: August 7, 1995
    Date of Patent: February 17, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventors: Rupa Doshi, Jon Nixon, Robert J. Collier, Jr.
  • Patent number: 5691360
    Abstract: Compounds having both calcium antagonist and antioxidant activity are disclosed. The compounds are useful in preventing or alleviating damage to tissues at the cellular level. Methods of treatment which employ these properties of the compounds and corresponding pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 25, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, George Barnes, Robert J. Collier, Jr.
  • Patent number: 5646149
    Abstract: Compounds having both calcium antagonist and antioxidant activity are disclosed. The compounds are useful in preventing or alleviating damage to tissues at the cellular level. Methods of treatment which employ these properties of the compounds and corresponding pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, George Barnes, Robert J. Collier, Jr.
  • Patent number: 5424321
    Abstract: Compounds having both calcium antagonist and antioxidant activity are disclosed. The compounds are useful in preventing or alleviating damage to tissues at the cellular level. Methods of treatment which employ these properties of the compounds and corresponding pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: December 8, 1993
    Date of Patent: June 13, 1995
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, George Barnes, Robert J. Collier, Jr.
  • Patent number: 5374523
    Abstract: An assay for determining the presence in bovine genetic material of a genetic marker located on the bovine somatotropin gene indicative of an inheritable trait of increased milk production is provided. The marker is a polymorphism in the gene encoding somatotropin at amino acid position 126 which results in two forms of somatotropin existing in bovine. The assay comprises analyzing a bovine to determine its genotype with respect to the somatotropin gene. Bovine with the desired marker can be selected for inclusion in breeding programs or for milking. The desired marker indicative of superior milk production is dependent upon the breed of cattle. Holstein cattle that are homozygous for the leucine forms of somatotropin are desired. Jersey cattle that are homozygous for the valine form of somatotropin are desired. A kit for performing the assay is also provided.
    Type: Grant
    Filed: August 10, 1992
    Date of Patent: December 20, 1994
    Assignee: Monsanto Company
    Inventors: Robert J. Collier, Scott D. Hauser, Gwen G. Krivi, Matthew C. Lucy
  • Patent number: 5182302
    Abstract: The growth of milk-producing mammary parenchyma in a mammal can be significantly enhanced by administering to the mammal by intramammary infusion a substance having a mitogenic effect on mammary epithelial cells in said mammal. Good growth enhancement can be achieved using very small quantities of such substances, and in relatively short periods of time.
    Type: Grant
    Filed: June 28, 1991
    Date of Patent: January 26, 1993
    Assignee: Monsanto Company
    Inventors: Robert J. Collier, Michael F. McGrath
  • Patent number: 5130300
    Abstract: The growth of milk-producing mammary parenchyma in a mammal can be significantly enhanced by administering to the mammal by intramammary infusion a substance having a mitogenic effect on mammary epithelial cells in said mammal. Good growth enhancement can be achieved using very small quantities of such substances, and in relatively short periods of time.
    Type: Grant
    Filed: March 14, 1990
    Date of Patent: July 14, 1992
    Assignee: Monsanto Company
    Inventors: Robert J. Collier, Michael F. McGrath
  • Patent number: 5130299
    Abstract: The growth of milk-producing mammary parenchyma in a mammal can be significantly enhanced by administering to the mammal by intramammary infusion a substance having a mitogenic effect on mammary epithelial cells in said mammal. Good growth enhancement can be achieved using very small quantities of such substances, and in relatively short periods of time.
    Type: Grant
    Filed: June 28, 1991
    Date of Patent: July 14, 1992
    Assignee: Monsanto Company
    Inventors: Robert J. Collier, Michael F. McGrath
  • Patent number: 5059586
    Abstract: The growth of milk-producing mammary parenchyma in a mammal can be significantly enhanced by administering to the mammal by intramammary infusion a substance having a mitogenic effect on mammary epithelial cells in said mammal. Good growth enhancement can be achieved using very small quantities of such substances, and in relatively short periods of time.
    Type: Grant
    Filed: September 2, 1987
    Date of Patent: October 22, 1991
    Assignee: Monsanto Company
    Inventors: Robert J. Collier, Michael F. McGrath
  • Patent number: 4393312
    Abstract: For a given resolution or address dimension, the pattern-writing speed of an electron beam exposure system is increased by utilizing a new mode of raster scanning. In the new mode, the writing spot dimensions of the electron beam are varied rapidly during the scan. In an electron column designed for variable-spot raster scanning, an illuminated aperture is demagnified to form the writing spot. By imaging a first aperture upon a second aperture and rapidly deflecting the image of the first aperture, the portion of the second aperture that is illuminated by the electron beam is altered. In that way, the spot size is selectively varied in a high-speed way during the raster scanning process.
    Type: Grant
    Filed: November 29, 1977
    Date of Patent: July 12, 1983
    Assignee: Bell Telephone Laboratories, Incorporated
    Inventors: Robert J. Collier, Michael G. R. Thomson
  • Patent number: 4167676
    Abstract: An attractive high-throughput technique for writing microcircuit patterns with a scanning electron spot of variable size is described in application Ser. No. 855,608, filed Nov. 29, 1977. In such an electron beam exposure system, two spaced-apart apertured mask plates with a deflector therebetween are included in the electron column of the system. As described herein, a third apertured mask plate and an associated deflector are serially added to the aforenoted components in the column. In this way, the throughput and other performance characteristics of such a system are significantly enhanced.
    Type: Grant
    Filed: February 21, 1978
    Date of Patent: September 11, 1979
    Assignee: Bell Telephone Laboratories, Incorporated
    Inventor: Robert J. Collier
  • Patent number: 4060620
    Abstract: The administration of reserpine to nonlactating dairy cattle produces a marked increase in circulating serum prolactin levels. The parenteral administration of reserpine to nonlactating cows which have been hormonally induced into lactation, as by the parenteral administration of an estrogen and progesterone, and dexamethasone, results in a substantial rise in milk production.
    Type: Grant
    Filed: May 17, 1976
    Date of Patent: November 29, 1977
    Assignee: University of Illinois Foundation
    Inventors: Dale E. Bauman, Robert J. Collier, Ray L. Hays