Abstract: A serial packet sync encoder is used to encode a serial packet sync datastream. In an embodiment, the serial packet sync datastream is made up of the packet sync vector and a unique preamble bit sequence that is preselected. In another embodiment, the serial packet sync datastream is made up of a non-unique bit sequence. A serial packet sync transmitter is used to transmit the serial packet sync datastream. A serial packet sync receiver is provided for receiving the serial packet sync datastream. In an embodiment, the serial packet sync transmitter and the serial packet sync receiver are shift registers. In this way, the serial packet sync datastream can be transmitted and received using only a single pin. The serial packet sync datastream is useful for providing an indication that an event, such as a grant arrival, has occurred. A preamble comparator is provided to compare the received serial packet sync datastream and the preselected preamble to determine if the two match.

Abstract: A serial packet sync encoder is used to encode a serial packet sync datastream. In an embodiment, the serial packet sync datastream is made up of the packet sync vector and a unique preamble bit sequence that is preselected. In another embodiment, the serial packet sync datastream is made up of a non-unique bit sequence. A serial packet sync transmitter is used to transmit the serial packet sync datastream. A serial packet sync receiver is provided for receiving the serial packet sync datastream. In an embodiment, the serial packet sync transmitter and the serial packet sync receiver are shift registers. In this way, the serial packet sync datastream can be transmitted and received using only a single pin. The serial packet sync datastream is useful for providing an indication that an event, such as a grant arrival, has occurred. A preamble comparator is provided to compare the received serial packet sync datastream and the preselected preamble to determine if the two match.

Abstract: Data packets transmitted over a cable network are suppressed by hardware at the transmitting end and expanded on the receiving end. This conserves bandwidth as well as reduces the processing resource requirements in both the CM and the CMTS. An extended header element is added to a data packet that is to be transmitted over the cable network. The extended header element contains an index that is used along with the SID to access a rule. The rule is used to determine which bytes are to be suppressed at the transmitter and expanded at the receiver.

Abstract: A plurality of CMTS devices are linked together and synchronized to facilitate communication between the respective CMTS devices and respective downstream cable modems. According to one embodiment of the invention, one of the CMTS devices is designated as a master device, and the other CMTS devices are designated as slave devices. The respective CMTS devices are connected to each other by means of a synchronization bus. The master CMTS device then generates and broadcasts a future time stamp value, which is received by the respective slave CMTS devices. When the time stamp counter in the master CMTS device reaches the transmitted value, a control signal is broadcast over the synchronization bus. The slave CMTS devices then retrieve the time stamp value and reset their respective local time stamp counters to the received value. In this manner, the CMTS devices are synchronized.

Abstract: Upstream requests such a bandwidth requests, are processed by CMTS out of order on a priority basis to reduce latency in responding to the request. Specifically, a cable modem termination system (CMTS) is connected to a plurality of cable modems by a cable plant. The CMTS has a burst receiver adapted to be connected to the cable plant to process upstream data packet units and bandwidth requests transmitted by the cable modems. Each packet includes a header that uniquely distinguishes the bandwidth requests from other data types. Packet data units are arranged in a first memory queue. Bandwidth requests are arranged in a second memory queue. The headers of the packets processed by the burst receiver are inspected as they arrive at the CMTS to determine if the packets are packet data units or bandwidth requests. Packet data units are routed to the first memory queue. Bandwidth requests are routed to the second memory queue.

Abstract: Data packets transmitted over a cable network are suppressed by hardware at the transmitting end and expanded on the receiving end. This conserves bandwidth as well as reduces the processing resource requirements in both the CM and the CMTS. An extended header element is added to a data packet that is to be transmitted over the cable network. The extended header element contains an index that is used along with the SID to access a rule. The rule is used to determine which bytes are to be suppressed at the transmitter and expanded at the receiver.

Abstract: A plurality of CMTS devices are linked together and synchronized to facilitate communication between the respective CMTS devices and respective downstream cable modems. According to one embodiment of the invention, one of the CMTS devices is designated as a master device, and the other CMTS devices are designated as slave devices. The respective CMTS devices are connected to each other by means of a synchronization bus. The master CMTS device then generates and broadcasts a future time stamp value, which is received by the respective slave CMTS devices. When the time stamp counter in the master CMTS device reaches the transmitted value, a control signal is broadcast over the synchronization bus. The slave CMTS devices then retrieve the time stamp value and reset their respective local time stamp counters to the received value. In this manner, the CMTS devices are synchronized.

Abstract: Data packets transmitted over a cable network are suppressed by hardware at the transmitting end and expanded on the receiving end. This conserves bandwidth as well as reduces the processing resource requirements in both the CM and the CMTS. An extended header element is added to a data packet that is to be transmitted over the cable network. The extended header element contains an index that is used along with the SID to access a rule. The rule is used to determine which bytes are to be suppressed at the transmitter and expanded at the receiver.

Abstract: A serial packet sync encoder is used to encode a serial packet sync datastream. In an embodiment, the serial packet sync datastream is made up of the packet sync vector and a unique preamble bit sequence that is preselected. In another embodiment, the serial packet sync datastream is made up of a non-unique bit sequence. A serial packet sync transmitter is used to transmit the serial packet sync datastream. A serial packet sync receiver is provided for receiving the serial packet sync datastream. In an embodiment, the serial packet sync transmitter and the serial packet sync receiver are shift registers. In this way, the serial packet sync datastream can be transmitted and received using only a single pin. The serial packet sync datastream is useful for providing an indication that an event, such as a grant arrival, has occurred. A preamble comparator is provided to compare the received serial packet sync datastream and the preselected preamble to determine if the two match.

Abstract: A plurality of CMTS devices are linked together and synchronized to facilitate communication between the respective CMTS devices and respective downstream cable modems. According to one embodiment of the invention, one of the CMTS devices is designated as a master device, and the other CMTS devices are designated as slave devices. The respective CMTS devices are connected to each other by means of a synchronization bus. The master CMTS device then generates and broadcasts a future time stamp value, which is received by the respective slave CMTS devices. When the time stamp counter in the master CMTS device reaches the transmitted value, a control signal is broadcast over the synchronization bus. The slave CMTS devices then retrieve the time stamp value and reset their respective local time stamp counters to the received value. In this manner, the CMTS devices are synchronized.

Abstract: The invention provides a method for treating leukemia in a patient. The method comprises administering to the patient a substance that increases expression of folate receptor &bgr; on leukemia cells in the patient, called a FR-&bgr; inducer, and administering a folate-conjugated therapeutic that targets the leukemia cells in the patient. The invention also comprises pharmaceutical compositions containing one or both of a FR-&bgr; inducer and a folate-conjugated therapeutic.

Abstract: A network gateway is configured to facilitate on line and off line bi-directional communication between a number of near end data and telephony devices with far end data termination devices via a hybrid fiber coaxial network and a cable modem termination system. The described network gateway combines a QAM receiver, a transmitter, a DOCSIS MAC, a CPU, a voice and audio processor, a voice synchronizer, an Ethernet MAC, and a USB controller to provide high performance and robust operation.

Abstract: A simple, rapid method for creating a lipidic vector for delivery of a therapeutic molecule entails bringing the molecule into contact with a polycation, thereby forming a complex, and then mixing the complex with an anionic lipidic preparation. Tissue-specific targeting peptides, fusogenic peptides and nucleus-targeting peptides also can be added to the lipid preparation. The result is a stable lipidic vector of reduced immunogenicity and cytotoxicity. The vector also displays enhanced transfection activity.

Abstract: A mandrel device which guides the end of a pipe or tube to a position outwardly of the path of an expander body, with a camming mechanism to force the expander body from an inward position to an outward position, and holding that outward position so as to achieve the desired gasket-receiving enlargement of the tubular work object. In a subsequent stage, another camming feature forces the expander body radially inwardly, to permit the tubular work object, now carrying the sealing ring in a position which would mean interference by the expander body, to be released over the end of the mandrel. The two camming components are carried by sub-assemblies axially movable with respect to stationary parts of the mandrel; and they are interrelated to have both movement together and movement with respect to one another, achieving the outward and inward camming effects in a plural-stage motion sequence and nature.

Abstract: Oil-soluble spacing agents for use in fracturing underground oil or gas formations comprising polymerized dimethyl-alpha-methylstyrenes.