Patents by Inventor Robert J. Smith

Robert J. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8913693
    Abstract: A method of balancing a quadrature modulator includes exciting an in-phase input of the quadrature module and sweeping a phase of an injection signal through a range of degrees, and determining a plurality of in-phase DC components. The method further includes exciting a quadrature input of the quadrature module and sweeping a phase of the injection signal through the range of degrees, and determining a plurality of quadrature DC components. An in-phase sinusoidal equivalent of the plurality of in-phase DC components and a quadrature sinusoidal equivalent of the plurality of quadrature DC components may be determined. At least one correction factor that balances the quadrature modulator may be determined based on a comparison between the in-phase sinusoidal equivalent and the quadrature sinusoidal equivalent.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: December 16, 2014
    Assignees: Raytheon Company, Purdue Research Foundation
    Inventors: Robert J. Smith, Abdullah Eroglu
  • Patent number: 8883455
    Abstract: An automated method for detecting the presence of a nucleic acid in a sample, where the method is performed within a housing of a self-contained, stand-alone analyzer. The method includes purifying the nucleic acid after it has been immobilized on a magnetically-responsive solid support. A pipette of the analyzer is used to form a reaction mixture comprising the purified nucleic acid and all reagents required to perform a nucleic acid amplification. Amplification products are synthesized that include a nucleotide sequence contained in the nucleic acid or the complement of the nucleic acid. The amplification products are exposed to a probe in a mixture, where the probe forms a hybrid with one of the amplification products. The formation of the hybrid in the mixture provides an indication of the presence of the nucleic acid in the sample.
    Type: Grant
    Filed: September 11, 2013
    Date of Patent: November 11, 2014
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Ralph E. Burns, Ernest V. Hansberry, Glenn A. Horner, Cheryl A. Jakub, John E. Kling, Donald J. Nieglos, Robert E. Schneider, Robert J. Smith
  • Publication number: 20140248619
    Abstract: An automated method for detecting the presence of a nucleic acid in a sample, where the method is performed within a housing of a self-contained, stand-alone analyzer. The method includes purifying the nucleic acid after it has been immobilized on a magnetically-responsive solid support. A pipette of the analyzer is used to form a reaction mixture comprising the purified nucleic acid and all reagents required to perform a nucleic acid amplification. Amplification products are synthesized that include a nucleotide sequence contained in the nucleic acid or the complement of the nucleic acid. The amplification products are exposed to a probe in a mixture, where the probe forms a hybrid with one of the amplification products. The formation of the hybrid in the mixture provides an indication of the presence of the nucleic acid in the sample.
    Type: Application
    Filed: May 21, 2014
    Publication date: September 4, 2014
    Applicant: Gen-Probe Incorporated
    Inventors: Kelly G. AMMANN, Ralph E. BURNS, Ernest V. HANSBERRY (Deceased), Glenn A. HORNER, Cheryl A. JAKUB, John E. KLING, Donald J. NIEGLOS, Robert E. SCHNEIDER, Robert J. SMITH
  • Patent number: 8709814
    Abstract: In a computer-controlled, automated method, a nucleic acid amplification procedure is performed within a prescribed incubation temperature range within an instrument that comprises at least one thermal element situated at a first location of the instrument and an amplification incubator situated at a second, spaced-apart location of the instrument. A receptacle and its contents are exposed to the thermal element for a predetermined period of time at the first location, such that the temperature of the contents of the receptacle is adjusted to approximate the incubation temperature. The receptacle is then moved from the first location and into the amplification incubator, and, in the amplification incubator, a nucleic acid contained in the contents of the receptacle is subjected to the nucleic acid amplification procedure.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: April 29, 2014
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Robert E. Schneider, Robert J. Smith
  • Publication number: 20140011295
    Abstract: An automated method for detecting the presence of a nucleic acid in a sample, where the method is performed within a housing of a self-contained, stand-alone analyzer. The method includes purifying the nucleic acid after it has been immobilized on a magnetically-responsive solid support. A pipette of the analyzer is used to form a reaction mixture comprising the purified nucleic acid and all reagents required to perform a nucleic acid amplification. As a result of the nucleic acid amplification, amplification products are synthesized that include a nucleotide sequence contained in the nucleic acid or the complement of the nucleic acid. The amplification products are exposed to a probe in a mixture, where the probe forms a hybrid with one of the amplification products. A label associated with the probe is detected as an indication of the formation of the hybrid, and the formation of the hybrid in the mixture provides an indication of the presence of the nucleic acid in the sample.
    Type: Application
    Filed: September 11, 2013
    Publication date: January 9, 2014
    Applicant: Gen-Probe Incorporated
    Inventors: Kelly G. AMMANN, Ralph E. BURNS, Ernest V. HANSBERRY (Deceased), Glenn A. HORNER, Cheryl A. JAKUB, John E. KLING, Donald J. NIEGLOS, Robert E. SCHNEIDER, Robert J. SMITH
  • Patent number: 8580574
    Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: November 12, 2013
    Assignee: Gen-Probe Incorporated
    Inventor: Robert J. Smith
  • Patent number: 8569019
    Abstract: An automated process for isolating and amplifying a target nucleic acid in a self-contained analyzer.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: October 29, 2013
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Ralph E. Burns, Ernest V. Hansberry, Glenn A. Horner, Cheryl A. Jakub, John E. Kling, Donald J. Nieglos, Robert E. Schneider, Robert J. Smith
  • Patent number: 8569020
    Abstract: An automated method for performing multiple nucleic acid amplification procedures in multiple receptacles of a set of receptacles contained in an analyzer.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: October 29, 2013
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Ralph E. Burns, Ernest V. Hansberry, Glenn A. Horner, Cheryl A. Jakub, John E. Kling, Donald J. Nieglos, Robert E. Schneider, Robert J. Smith
  • Patent number: 8546110
    Abstract: An automated method for preparing and amplifying a sequence contained in a nucleic acid present in a sample, the nucleic acid being prepared in a receptacle that is part of a unit that includes a plurality of receptacles and holds a removable contact-limiting element for aspirating a fluid component of the sample from the receptacle.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: October 1, 2013
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Ralph E. Burns, Ernest V. Hansberry, Glenn A. Horner, Cheryl A. Jakub, John E. Kling, Donald J. Nieglos, Robert E. Schneider, Robert J. Smith
  • Publication number: 20130252511
    Abstract: Disclosed are moisturizing fabric materials for use in articles of wear such as bras. The moisturizing fabric materials include a moisturizer comprising plant oil, plant extract, and an emulsifier. The moisturizer is bonded to polymeric fabric material via a bonding agent to provide the moisturizing fabric material. Also disclosed is a method of manufacturing an article of wear such as a bra using moisturizing fabric material.
    Type: Application
    Filed: March 23, 2012
    Publication date: September 26, 2013
    Applicant: VICTORIA'S SECRET STORE BRAND MANAGEMENT, INC.
    Inventors: Dulce Almario, Mark Knitowski, Nathalie Martinet, Robert J. Smith, Mayur Vansia, Jasmine Yip
  • Patent number: 8440429
    Abstract: An automated method for preparing and amplifying a sequence contained in a nucleic acid present in a sample, the nucleic acid being prepared in a receptacle that is part of a unit that includes a plurality of receptacles and holds a removable contact-limiting element for aspirating a fluid component of the sample from the receptacle.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: May 14, 2013
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Ralph E. Burns, Ernest V. Hansberry, Glenn A. Horner, Cheryl A. Jakub, John E. Kling, Donald J. Nieglos, Robert E. Schneider, Robert J. Smith
  • Patent number: 8337753
    Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: December 25, 2012
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Robert E. Schneider, Robert J. Smith
  • Publication number: 20120301924
    Abstract: In a computer-controlled, automated method, a nucleic acid amplification procedure is performed within a prescribed incubation temperature range within an instrument that comprises at least one thermal element situated at a first location of the instrument and an amplification incubator situated at a second, spaced-apart location of the instrument. A receptacle and its contents are exposed to the thermal element for a predetermined period of time at the first location, such that the temperature of the contents of the receptacle is adjusted to approximate the incubation temperature. The receptacle is then moved from the first location and into the amplification incubator, and, in the amplification incubator, a nucleic acid contained in the contents of the receptacle is subjected to the nucleic acid amplification procedure.
    Type: Application
    Filed: April 16, 2012
    Publication date: November 29, 2012
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Kelly G. AMMANN, Robert E. SCHNEIDER, Robert J. SMITH
  • Patent number: 8318500
    Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: November 27, 2012
    Assignee: Gen-Probe, Incorporated
    Inventors: Kelly G. Ammann, Robert E. Schneider, Robert J. Smith
  • Patent number: 8309358
    Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: November 13, 2012
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Robert E. Schneider, Robert J. Smith
  • Patent number: 8282343
    Abstract: A vane for a gas turbine engine includes a cap arrangement having a cap insert and a cap adapted to receive the insert. The cap insert has a wall defining a through passage from top to bottom of the cap insert for receiving a cable or the like therethrough. The wall has a slot with a convoluted profile.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: October 9, 2012
    Assignee: Rolls-Royce PLC
    Inventor: Robert J. Smith
  • Patent number: 8221682
    Abstract: An automated analyzer for performing multiple diagnostic assays includes multiple modules in which aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a sample, pre-heating the sample, incubating the sample, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. A receptacle transporting system moves reaction receptacles from one station to the next. A method for performing an assay includes an automated process for isolating and amplifying a target analyte. The process is performed by moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for pre-heating and incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the analyte after the separation step and before incubation.
    Type: Grant
    Filed: September 14, 2011
    Date of Patent: July 17, 2012
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Robert E. Schneider, Robert J. Smith
  • Patent number: 8192992
    Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.
    Type: Grant
    Filed: October 25, 2007
    Date of Patent: June 5, 2012
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Robert E. Schneider, Robert J. Smith
  • Publication number: 20120070884
    Abstract: An automated analyzer for performing multiple diagnostic assays includes multiple modules in which aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a sample, pre-heating the sample, incubating the sample, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. A receptacle transporting system moves reaction receptacles from one station to the next. A method for performing an assay includes an automated process for isolating and amplifying a target analyte. The process is performed by moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for pre-heating and incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the analyte after the separation step and before incubation.
    Type: Application
    Filed: September 14, 2011
    Publication date: March 22, 2012
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Kelly G. AMMANN, Robert E. Schneider, Robert J. Smith
  • Patent number: 8137620
    Abstract: An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.
    Type: Grant
    Filed: October 9, 2007
    Date of Patent: March 20, 2012
    Assignee: Gen-Probe Incorporated
    Inventors: Kelly G. Ammann, Robert E. Schneider, Robert J. Smith