Abstract: A multi-layer, super-planar laminate structure can be formed from distinctly patterned layers. The layers in the structure can include at least one rigid layer and at least one flexible layer; the rigid layer includes a plurality of rigid segments, and the flexible layer can extend between the rigid segments to serve as a joint. The layers are then stacked and bonded at selected locations to form a laminate structure with inter-layer bonds, and the laminate structure is flexed at the flexible layer between rigid segments to produce an expanded three-dimensional structure, wherein the layers are joined at the selected bonding locations and separated at other locations. A layer with electrical wiring can be included in the structure for delivering electric current to devices on or in the laminate structure.

Abstract: The carbohydrate processing enzyme PNGase F was catalytically inactivated through mutation. Additional mutations yielded a catalytically inactive carbohydrate-binding protein with lectin-like properties including high affinity and specificity N-linked glycans, O-linked glycans, or both.

Abstract: A thermal powered medical device generates power from a temperature differential between a living body and a differential temperature source. The power is supplied to power one or more electrical components of the medical device.

Abstract: An Engine Start and Battery Support Module for a vehicle is provided that utilizes a bank of Ultra Capacitors (UCs) charged with or without running the vehicle's alternator to levels that support both engine starting assistance and hotel load support. The UCs' per-cell charge can be adjusted and raised during periods of low temperatures and even higher during ultralow temperatures. The adjustment, which can be dynamic and/or automatic, increases the UC energy storage capability. Further, the release of energy from the UCs is controlled by a pulse width modulation (PWM) controller based on the DC bus voltage. The UCs can be charged either from an onboard DC/DC converter, an AC hook up, or from smartly switching the banks of UCs between parallel and serial configurations.

Abstract: A skin measuring microscope includes a housing, an electronic imager disposed along an imaging axis, and an illumination system. The illumination system includes a plurality of LEDs disposed in a ring-like configuration adjacent a distal end of the housing.

Abstract: A system and a method for testing a visual field of a subject are described. The method includes determining inter-eye distance of the subject. Visual stimuli are displayed on a left display region and a right display region of a two-dimensional display to the subject based on the determined inter-eye distance. The left display region is configured to display content specific to the left eye and the right display region is configured to display content specific to the right eye of the subject. Subject responses to the visual stimuli are tracked. Based on the subject responses, a condition of the visual field of each eye the subject is evaluated and then results of the evaluation describing the subject's visual field condition is reported or stored.

Abstract: A handheld device includes an electronic instrument and a capacitive power supply for storing and delivering power to the electronic instrument. The capacitive power supply includes at least one capacitor, and an electronic circuit operable to boost a voltage from the capacitor to a higher voltage for use by the electronic instrument. The capacitive power supply can be rapidly recharged. Some configurations include an accelerometer which permits the handheld device to detect movement and perform various operations responsive to detected movement. A dual charging station is also disclosed.

Abstract: In some embodiments, a dielectric elastomer device may include at least first and second dielectric elastomer layers, and a first layer of conductive particles disposed between the first and second dielectric elastomer layers and forming a first electrode of the device, wherein portions of the second dielectric elastomer layer are directly bonded with portions of the first dielectric elastomer layer through the first layer of the conductive particles. The dielectric elastomer layer may, for example, comprise a cured acrylic elastomer precursor with an additive including urethane, polybutadiene, or silicone. Electrodes in different layers may be interconnected by infusing a liquid or semi-liquid conductive material in contact with each of a plurality of the electrodes of the actuator or sensor device, and solidifying the conductive material to form a conductive path that interconnects the plurality of electrodes.

Abstract: A printed stretchable strain sensor comprises a seamless elastomeric body and a strain-sensitive conductive structure embedded in the seamless elastomeric body. The strain-sensitive conductive structure comprises one or more conductive filaments arranged in a continuous pattern. A method of printing a stretchable strain sensor comprises depositing one or more conductive filaments in a predetermined continuous pattern into or onto a support matrix. After the depositing, the support matrix is cured to embed a strain-sensitive conductive structure in a seamless elastomeric body.

Abstract: A hand-held medical device includes a housing, an electronic imager, and an optical system aligned with the electronic imager along an imaging axis of the device. An illumination system includes at least one light source for directing light towards a target of interest, as well as a display connected to the electronic imager and attached to the housing. A processor, disposed within the housing, is connected to the electronic imager, the illumination assembly and the display, and includes processing logic and data storage for storing a plurality of images.

Abstract: A temperature determination method includes temporarily contacting a forehead of a subject with a first surface of a removable patch, and exposing a second surface of the patch opposite the first surface to ambient conditions. The method also includes sensing a temperature of the first surface of the patch while the first surface is in contact with the forehead at a first location thereon, sensing a temperature of the second surface of the patch, and calculating a sub-skull temperature of the subject based on the sensed temperatures of the first and second surface.

Abstract: A method of making an actuator having a complex internal shape includes providing a core of a shape that defines an internal cavity of an actuator; molding an actuator around the core, wherein the core occupies the internal cavity of the actuator, the cavity having an opening; generating a pressure differential between an exterior surface of the actuator and the internal cavity of the actuator, wherein the external pressure is less than the internal pressure, to expand the actuator cavity; and removing the core through the opening of the expanded actuator cavity.

Abstract: A printed stretchable strain sensor comprises a seamless elastomeric body and a strain-sensitive conductive structure embedded in the seamless elastomeric body. The strain-sensitive conductive structure comprises one or more conductive filaments arranged in a continuous pattern. A method of printing a stretchable strain sensor comprises depositing one or more conductive filaments in a predetermined continuous pattern into or onto a support matrix. After the depositing, the support matrix is cured to embed a strain-sensitive conductive structure in a seamless elastomeric body.

Abstract: A self-folding machine comprises a laminate including a flexible layer with a first side and a second side; a first rigid layer including at least one gap laminated to the first side of the flexible layer; a second rigid layer including at least one gap laminated to the second side of the flexible layer, wherein the rigid layers are more rigid than the flexible layer; a first contractible layer laminated to the first rigid layer and extending across at least one gap in the first rigid layer; and a second contractible layer laminated to the second rigid layer and extending across at least one gap in the second rigid layer, wherein the first and second contractible layers retract to respectively create folds in the machine across gaps in the first and second rigid layers when activated.

Abstract: In a method for printing an RFID tag on an object, a deposition mask is applied to the surface of an object. With the deposition mask on the surface of the object, RFID materials are deposited on at least one portion of the surface exposed by aperture(s) in the deposition mask. In particular embodiments, RFID tags can be deposited on medical instruments.

Abstract: A light-intensity-based forced sensor comprises a Sarrus linkage, a biasing mechanism, a light emitter, and a light detector includes a first plate, a second plate, and at least one collapsible linkage pivotably coupled to both the first and the second plates. The biasing mechanism biases the collapsible linkage toward an extended configuration. The light emitter is coupled with and displaceable with the first plate; and the light detector is coupled with and displaceable with the second plate and configured to receive light emitted from the light emitter and generate an electrical signal in response to light received from the light emitter, wherein the generated electrical signal provides an indication of the distance between the first plate and the second plate. The sensor can be distally mounted on, e.g., an endoscope to provide haptic feedback at the distal end of the endoscope.

Abstract: Provided are lectenz molecules, which are mutated carbohydrate processing enzyme enzymes that are catalytically inactive and that have had their substrate affinity increased by at least 1.2 fold. Further provided are methods for making and methods of using such lectenz. Further provided are compositions and methods directed to the multiplexed analysis of carbohydrates and carbohydrate containing compounds. The compositions and methods utilize suspension array technology (SAT) and an array of different carbohydrate binding molecules, each carbohydrate binding molecules with a known carbohydrate binding specificity, to obtain a glycoprofile of the carbohydrate structure(s) in a sample. Each carbohydrate binding molecule of a given specificity is linked to the external surface of a population of individually addressable particles.

Abstract: An Engine Start and Battery Support Module for a vehicle is provided that utilizes a bank of Ultra Capacitors (UCs) charged with or without running the vehicle's alternator to levels that support both engine starting assistance and hotel load support. The UCs' per-cell charge can be adjured and raided during periods of low temperatures and even higher during ultralow temperatures. The adjustment, which can be dynamic and/or automatic, increases the UC energy storage capability. Further, the release of energy from the UCs is controlled by a pulse width modulation (PWM) controller based on the DC bus voltage. The UCs can be charged either from an onboard DC/DC converter, an AC hook up, or from smartly switching the banks of UCs between parallel and serial configurations.

Abstract: An example system includes a patch defining a first surface and a second surface opposite the first surface. The first surface is removably attachable to skin of a subject. The patch includes a conductor associated with the first surface, a first sensor configured to determine a temperature of the conductor, and a second sensor configured to determine an additional temperature. The first sensor is separated from the second sensor by material having a known thermal resistance. The patch also includes a transmitter operably connected to the first and second sensors.

Abstract: An elastic strain sensor can be incorporated into an artificial skin that can sense flexing by the underlying support structure of the skin to detect and track motion of the support structure. The unidirectional elastic strain sensor can be formed by filling two or more channels in an elastic substrate material with a conductive liquid. At the ends of the channels, a loop port connects the channels to form a serpentine channel. The channels extend along the direction of strain and the loop portions have sufficiently large cross-sectional area in the direction transverse to the direction of strain that the sensor is unidirectional. The resistance is measured at the ends of the serpentine channel and can be used to determine the strain on the sensor. Additional channels can be added to increase the sensitivity of the sensor. The sensors can be stacked on top of each other to increase the sensitivity of the sensor.