Patents by Inventor Robert Lanza

Robert Lanza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11566228
    Abstract: Methods of generating and expanding human hemangio-colony forming cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: January 31, 2023
    Assignee: Astellas Institute for Regenerative Medicine
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Publication number: 20220288131
    Abstract: The present invention generally relates to novel mesoderm-derived vascular progenitor cells (meso-VPCs) and methods of producing the meso-VPCs. The present invention also relates to methods of treating a vascular disease, such as critical limb ischemia, by administering the meso-VPCs into a subject.
    Type: Application
    Filed: August 27, 2020
    Publication date: September 15, 2022
    Inventors: Maria Mirotsou, Nutan Prasain, Amrita Singh, Robert Lanza
  • Publication number: 20220280572
    Abstract: The present invention provides methods for treating vascular diseases with hemogenic endothelial cells (HEs) obtained in vitro from pluripotent stem cells. The present invention also provides compositions and methods of producing the HEs.
    Type: Application
    Filed: August 27, 2020
    Publication date: September 8, 2022
    Inventors: Nagisa Sakurai, Maria Mirotsou, Nutan Prasain, Amrita Singh, Robert Lanza
  • Publication number: 20220277126
    Abstract: Systems and methods for obfuscating a circuit design are described. One of the methods includes receiving the circuit design from a user computing device. The circuit design includes a plurality of circuit components. The method further includes obfuscating each of the circuit components by transforming layout features associated with the circuit design into a generic layout feature representation. The generic layout feature representation excludes scaled representations of the layout features. The method also includes generating a visual representation of the obfuscated designs. Each of the obfuscated designs has an input port and an output port. The method further includes enabling placement of the obfuscated designs and routing between the input ports and the output ports of the obfuscated designs. The method includes generating an obfuscated integrated circuit design having a master input port, a master output port, the obfuscated designs, and the routing between the obfuscated designs.
    Type: Application
    Filed: May 16, 2022
    Publication date: September 1, 2022
    Inventors: Bertrand Irissou, John M. Hughes, Lucio Lanza, Mohamed K. Kassem, Michael S. Wishart, Rajeev Srivastava, Risto Bell, Robert Timothy Edwards, Sherif Eid, Greg P. Shaurette
  • Publication number: 20200263132
    Abstract: Methods for generating enucleated erythroid cells using pluripotent stem cells are provided. The methods permit the production of large numbers of cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Methods for generating megakaryocyte and platelets are also provided.
    Type: Application
    Filed: February 25, 2020
    Publication date: August 20, 2020
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Publication number: 20200157503
    Abstract: Methods of generating and expanding human hemangio-colony forming cells and non-engrafting hemangio cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells, non-engrafting hemangio cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Human non-engrafting hemangio cells are a novel progenitor cell population that is related to but distinct from the hemangioblast and human hemangio-colony forming cells. The invention also provides compositions, preparations, and solutions comprising hemangio-colony forming cells, non-engrafting hemangio cells or cells differentiated therefrom.
    Type: Application
    Filed: November 21, 2019
    Publication date: May 21, 2020
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Patent number: 10197694
    Abstract: Systems and methods for deploying and using a controlled-frequency downhole seismic source are provided. A downhole seismic source may be placed into a borehole in a geological formation and coupled rigidly to the geological formation via an edge of the borehole. A controlled-frequency seismic signal may be generated sufficient to enable a seismic measurement of the geological formation.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: February 5, 2019
    Assignee: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: James Minto, Robert Lanza, Ryosei Aoki, Herve Denaclara
  • Publication number: 20190017027
    Abstract: Methods of generating and expanding human hemangio-colony forming cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications.
    Type: Application
    Filed: February 22, 2018
    Publication date: January 17, 2019
    Applicant: Astellas Institute for Regenerative Medicine
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Publication number: 20190002828
    Abstract: Methods for generating enucleated erythroid cells using pluripotent stem cells are provided. The methods permit the production of large numbers of cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Methods for generating megakaryocyte and platelets are also provided.
    Type: Application
    Filed: April 25, 2018
    Publication date: January 3, 2019
    Applicant: Astellas Institute for Regenerative Medicine
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Patent number: 9988602
    Abstract: Methods for generating enucleated erythroid cells using pluripotent stem cells are provided. The methods permit the production of large numbers of cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Methods for generating megakaryocyte and platelets are also provided.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: June 5, 2018
    Assignee: Astellas Institute for Regenerative Medicine
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Patent number: 9938500
    Abstract: Methods of generating and expanding human hemangio-colony forming cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: April 10, 2018
    Assignee: Astellas Institute for Regenerative Medicine
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Publication number: 20170152481
    Abstract: Methods of generating and expanding human hemangio-colony forming cells and non-engrafting hemangio cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells, non-engrafting hemangio cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Human non-engrafting hemangio cells are a novel progenitor cell population that is related to but distinct from the hemangioblast and human hemangio-colony forming cells. The invention also provides compositions, preparations, and solutions comprising hemangio-colony forming cells, non-engrafting hemangio cells or cells differentiated therefrom.
    Type: Application
    Filed: July 6, 2016
    Publication date: June 1, 2017
    Applicant: Ocata Therapeutics, Inc.
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Publication number: 20170121681
    Abstract: Methods for generating enucleated erythroid cells using pluripotent stem cells are provided. The methods permit the production of large numbers of cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Methods for generating megakaryocyte and platelets are also provided.
    Type: Application
    Filed: March 24, 2016
    Publication date: May 4, 2017
    Applicant: Ocata Therapeutics, Inc.
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Patent number: 9562217
    Abstract: This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: February 7, 2017
    Assignee: Astellas Institute for Regenerative Medicine
    Inventors: Irina V. Klimanskaya, Robert Lanza
  • Publication number: 20160299246
    Abstract: Systems and methods for deploying and using a controlled-frequency downhole seismic source are provided. A downhole seismic source may be placed into a borehole in a geological formation and coupled rigidly to the geological formation via an edge of the borehole. A controlled-frequency seismic signal may be generated sufficient to enable a seismic measurement of the geological formation.
    Type: Application
    Filed: April 7, 2016
    Publication date: October 13, 2016
    Inventors: James Minto, Robert Lanza, Ryosei Aoki, Herve Denaclara
  • Patent number: 9410123
    Abstract: Methods of generating and expanding human hemangio-colony forming cells and non-engrafting hemangio cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells, non-engrafting hemangio cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Human non-engrafting hemangio cells are a novel progenitor cell population that is related to but distinct from the hemangioblast and human hemangio-colony forming cells. The invention also provides compositions, preparations, and solutions comprising hemangio-colony forming cells, non-engrafting hemangio cells or cells differentiated therefrom.
    Type: Grant
    Filed: May 6, 2009
    Date of Patent: August 9, 2016
    Assignee: Ocata Therapeutics, Inc.
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Patent number: 9383462
    Abstract: A seismic generation system may include an electrical source, a conductor coupled to the electrical source and to be positioned in a wellbore in a subterranean formation with a casing therein, and a seismic generation source assembly to be positioned in the wellbore and coupled to the conductor. The seismic generation source assembly may include a source element having a sealed housing, an armature within the sealed housing, source electromagnets coupled to the armature, and electromagnetic clamps coupled to the armature, each electromagnetic clamp having opposite magnetic poles. The sealed housing may include respective ferromagnetic portions adjacent the opposite magnetic poles of each electromagnetic clamp, and non-ferromagnetic portions between the opposite magnetic poles of each electromagnetic clamp.
    Type: Grant
    Filed: June 18, 2012
    Date of Patent: July 5, 2016
    Assignee: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: James Minto, Robert Lanza, Bradley Bryans, Leo M. Dekkers, Shantonu Ray
  • Publication number: 20160115450
    Abstract: Methods of generating and expanding human hemangio-colony forming cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications.
    Type: Application
    Filed: September 29, 2015
    Publication date: April 28, 2016
    Applicant: OCATA THERAPEUTICS, INC.
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Patent number: 9080150
    Abstract: This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells.
    Type: Grant
    Filed: May 22, 2012
    Date of Patent: July 14, 2015
    Assignee: Ocata Therapeutics, Inc.
    Inventors: Irina V. Klimanskaya, Robert Lanza
  • Patent number: 9040770
    Abstract: This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: May 26, 2015
    Assignee: Ocata Therapeutics, Inc.
    Inventors: Irina Klimanskaya, Robert Lanza