Patents by Inventor Robert Lanza

Robert Lanza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110117062
    Abstract: This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells.
    Type: Application
    Filed: August 17, 2010
    Publication date: May 19, 2011
    Applicant: Advanced Cell Technology, Inc.
    Inventors: Irina V. Klimanskaya, Robert Lanza
  • Publication number: 20110086424
    Abstract: Methods for generating enucleated erythroid cells using pluripotent stem cells are provided. The methods permit the production of large numbers of cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Methods for generating megakaryocyte and platelets are also provided.
    Type: Application
    Filed: May 6, 2009
    Publication date: April 14, 2011
    Applicant: ADVANCED CELL TECHNOLOGY, INC.
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Publication number: 20110064705
    Abstract: Methods of generating and expanding human hemangio-colony forming cells and non-engrafting hemangio cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells, non-engrafting hemangio cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications. Human non-engrafting hemangio cells are a novel progenitor cell population that is related to but distinct from the hemangioblast and human hemangio-colony forming cells. The invention also provides compositions, preparations, and solutions comprising hemangio-colony forming cells, non-engrafting hemangio cells or cells differentiated therefrom.
    Type: Application
    Filed: May 6, 2009
    Publication date: March 17, 2011
    Applicant: ADVANCED CELL TECHNOLOGY, INC.
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Patent number: 7893315
    Abstract: This present invention provides novel methods for deriving embryonic stem cells and embryo-derived cells from an embryo without requiring destruction of the embryo. The invention further provides cells and cell lines derived without embryo destruction, and the use of the cells for therapeutic and research purposes. It also relates to novel methods of establishing and storing an autologous stem cell line prior to implantation of an embryo, e.g., in conjunction with reproductive therapies such as IVF.
    Type: Grant
    Filed: May 3, 2007
    Date of Patent: February 22, 2011
    Assignee: Advanced Cell Technology, Inc.
    Inventors: Young Gie Chung, Robert Lanza, Irina V. Klimanskaya
  • Publication number: 20110028780
    Abstract: Methods for generating embryos using pluripotent stem cells are provided. The subject methods include methods for generating chimeric embryos, wherein only a subset of the cells of each embryo are genetically identical to the pluripotent stem cells used in the generation process. The subject methods also include methods for generating embryos that are identical or are essentially genetic clones of the pluripotent stem cells (e.g., the resulting embryos are substantially identical, genetically, to the pluripotent stem cells used in the generation process).
    Type: Application
    Filed: December 19, 2008
    Publication date: February 3, 2011
    Inventor: Robert Lanza
  • Publication number: 20100299765
    Abstract: This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells.
    Type: Application
    Filed: May 18, 2010
    Publication date: November 25, 2010
    Inventors: Irina Klimanskaya, Robert Lanza
  • Patent number: 7838727
    Abstract: This present invention provides novel methods for deriving embryonic stem cells, those cells and cell lines, and the use of the cells for therapeutic and research purposes without the destruction of the embryo. It also relates to novel methods of establishing and storing an autologous stem cell line prior to implantation of an embryo, e.g., in conjunction with reproductive therapies such as IVF.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: November 23, 2010
    Assignee: Advanced Cell Technology, Inc.
    Inventors: Robert Lanza, Young Chung, Michael D. West
  • Publication number: 20100240132
    Abstract: The present invention relates generally to the field of somatic cell nuclear transfer (SCNT) and to the creation of cloned animals and cells. The disclosure relates to a method of cloning a mammal, obtaining pluripotent cells such as embryonic stem cells, or for reprogramming a mammalian cell using an oocyte and a fertilized embryo.
    Type: Application
    Filed: February 22, 2008
    Publication date: September 23, 2010
    Inventors: Robert Lanza, Young Chung
  • Patent number: 7795025
    Abstract: This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: September 14, 2010
    Assignee: Advanced Cell Technology, Inc.
    Inventors: Irina V. Klimanskaya, Robert Lanza
  • Patent number: 7794704
    Abstract: This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: September 14, 2010
    Assignee: Advanced Cell Technology, Inc.
    Inventors: Irina V. Klimanskaya, Robert Lanza
  • Patent number: 7736896
    Abstract: This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells.
    Type: Grant
    Filed: July 20, 2005
    Date of Patent: June 15, 2010
    Assignee: Advanced Cell Technology, Inc.
    Inventors: Irina Klimanskaya, Robert Lanza
  • Publication number: 20090104697
    Abstract: An improved method of producing differentiated progenitor cells comprising obtaining inner cell mass cells from a blastocyst and inducing differentiation of the inner cell mass cells to produce differentiated progenitor cells. The differentiated progenitor cells may be transfected such that there is an addition, deletion or alteration of a desired gene. The differentiated progenitor cells are useful in cell therapy and as a I source of cells for the production of tissues and organs for transplantation. Also provided is a method of producing a lineage-defective human embryonic stem cell.
    Type: Application
    Filed: May 16, 2008
    Publication date: April 23, 2009
    Inventors: Jose Cibelli, Michael D. West, Robert Lanza
  • Publication number: 20080057041
    Abstract: This present invention provides novel methods for deriving embryonic stem cells and embryo-derived cells from an embryo without requiring destruction of the embryo. The invention further provides cells and cell lines derived without embryo destruction, and the use of the cells for therapeutic and research purposes. It also relates to novel methods of establishing and storing an autologous stem cell line prior to implantation of an embryo, e.g., in conjunction with reproductive therapies such as IVF.
    Type: Application
    Filed: May 3, 2007
    Publication date: March 6, 2008
    Inventors: Young Chung, Robert Lanza, Irina Klimanskaya
  • Publication number: 20080014180
    Abstract: Methods of generating and expanding human hemangio-colony forming cells in vitro and methods of expanding and using such cells are disclosed. The methods permit the production of large numbers of hemangio-colony forming cells as well as derivative cells, such as hematopoietic and endothelial cells. The cells obtained by the methods disclosed may be used for a variety of research, clinical, and therapeutic applications.
    Type: Application
    Filed: April 13, 2007
    Publication date: January 17, 2008
    Inventors: Robert Lanza, Shi-Jiang Lu
  • Publication number: 20060206953
    Abstract: This present invention provides novel methods for deriving embryonic stem cells, those cells and cell lines, and the use of the cells for therapeutic and research purposes without the destruction of the embryo. It also relates to novel methods of establishing and storing an autologous stem cell line prior to implantation of an embryo, e.g., in conjunction with reproductive therapies such as IVF.
    Type: Application
    Filed: November 4, 2005
    Publication date: September 14, 2006
    Inventors: Robert Lanza, Young Chung, Michael West
  • Publication number: 20060051332
    Abstract: Tissues produced by culture of cells produced by nuclear transfer on a matrix derived from nuclear transfer embryos or embryos and pluripotent cells provided by other methods are provided. These tissues are useful for cell therapy.
    Type: Application
    Filed: May 23, 2003
    Publication date: March 9, 2006
    Applicant: Advanced Cell Technology, Inc.
    Inventor: Robert Lanza
  • Publication number: 20060026694
    Abstract: This invention relates to methods for making immune compatible tissues and cells for the purpose of transplantation and tissue engineering, using the techniques of nuclear transfer and cloning. Also encompassed are methods for determining the effect on immune compatibility of expressed transgenes and other genetic manipulations of the engineered cells and tissues.
    Type: Application
    Filed: May 17, 2005
    Publication date: February 2, 2006
    Inventors: Robert Lanza, Michael West
  • Publication number: 20060018886
    Abstract: This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells.
    Type: Application
    Filed: July 20, 2005
    Publication date: January 26, 2006
    Inventors: Irina Klimanskaya, Robert Lanza
  • Publication number: 20050265976
    Abstract: An improved method of producing differentiated progenitor cells comprising obtaining inner cell mass cells from a blastocyst and inducing differentiation of the inner cell mass cells to produce differentiated progenitor cells. The differentiated progenitor cells may be transfected such that there is an addition, deletion or alteration of a desired gene. The differentiated progenitor cells are useful in cell therapy and as a I source of cells for the production of tissues and organs for transplantation. Also provided is a method of producing a lineage-defective human embryonic stem cell.
    Type: Application
    Filed: December 29, 2004
    Publication date: December 1, 2005
    Applicant: Advanced Cell Technology, Inc.
    Inventors: Jose Cibelli, Michael West, Robert Lanza
  • Publication number: 20050255596
    Abstract: This invention relates to methods for rejuvenating normal somatic cells and for making normal somatic cells of a different type having the same genotype as a normal somatic cell of interest. These cells have particular application in cell and tissue transplantation. Also encompassed are methods of re-cloning cloned animals, particularly methods where the offspring of cloned mammals are designed to be genetically altered in comparison to their cloned parent, e.g., that are “hyper-young.” These animals should be healthier and possess desirable properties relative to their cloned parent. Also included are methods for activating endogenous telomerase, EPC-1 activity, and or the ALT pathway and/or extending the life-span of a normal somatic cell, and other genes associated with cell aging and proliferation capacity.
    Type: Application
    Filed: March 9, 2005
    Publication date: November 17, 2005
    Inventors: Michael West, Robert Lanza, Jose Cibelli