Patents by Inventor Robert Leanna

Robert Leanna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of a renin inhibiting compound
    Patent number: 5275950
    Abstract: Intermediates and a process for their preparation are disclosed which are useful for the preparation of a renin inhibiting compound of the formula: ##STR1## wherein R is a nitrogen-containing heterocycle which is bonded via a nitrogen atom to the sulfonyl group, R.sub.6 is hydrogen, alkoxy, halogen or loweralkyl, R.sub.7 is loweralkyl having 2 to 7 carbon atoms, and R.sub.8 is loweralkyl, cycloalkyl, or aryl or a pharmaceutically acceptable acid addition salt thereof.
    Type: Grant
    Filed: February 10, 1993
    Date of Patent: January 4, 1994
    Assignee: Abbott Laboratories
    Inventors: Daniel A. Dickman, Bruce W. Horrom, Chi-Nung W. Hsiao, M. Robert Leanna, Hormoz Mazdiyasni, Howard E. Morton, Thomas M. Zydowsky, William R. Baker, Stephen L. Condon
  • Isomerically pure 2-piperidone compounds
    Patent number: 5229518
    Abstract: The present invention relates to intermediates useful in the process for the preparation of a compound of the formula: ##STR1## wherein R.sub.2a is hydrogen or loweralkyl, R.sub.2b is hydrogen, loweralkyl, cycloalkyl or phenyl and R.sub.1 is loweralkyl, cycloalky, cycloalkylalkyl, phenyl or benzyl. These intermediates are compounds of the formula: ##STR2## wherein R.sub.1, R.sub.2a and R.sub.2b are defined as above.
    Type: Grant
    Filed: November 20, 1991
    Date of Patent: July 20, 1993
    Assignee: Abbott Laboratories
    Inventors: Daniel J. Plata, Anthony K. L. Fung, Howard E. Morton, M. Robert Leanna, William R. Baker, John K. Pratt
  • Intermediates to 4-amino-hexahydrobenz[cd]indoles and processes therefor
    Patent number: 5212319
    Abstract: New intermediates, and processes therefor, provide an efficient method for deriving 4-amino-1,2,-2a,3,4,5-hexahydrobenz[cd]indoles, which are themselves intermediates to useful CNS agents, from the Kornfeld-Woodward ketone and like compounds. Preferred embodiments provide means for the preparation of substantially pure enantiomers of the desired 4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indole.
    Type: Grant
    Filed: November 26, 1991
    Date of Patent: May 18, 1993
    Assignee: Eli Lilly and Company
    Inventors: Thomas J. Kress, M. Robert Leanna, Michael J. Martinelli, Barry C. Peterson