Abstract: Improved methods for generating a virtual representation of an interior space such as a room are provided. Techniques for capturing and normalizing sets of points for polygon mesh generation that utilize augmented reality toolkits are also described. The improved methods comprise: techniques for generating a polygon mesh that incorporates a projecting extrusion; techniques for generating a polygon mesh that incorporates curved surfaces; and techniques for generating a polygon mesh in real-time.

Abstract: A pipetting head (100) for a liquid dispensing apparatus (10) for use with an array of removable pipettes (1010) is provided. The pipetting head has a pipette body mounting assembly (120) for holding the pipette bodies (1100) of the removable pipettes. a plunger mounting assembly (140) for holding the plungers (1200) of the removable pipettes, and a dispense drive actuator assembly (160) with a dispense drive mechanism (162) for moving the plunger mounting assembly along a drive axis. The pipetting head also includes a pipette body clamping mechanism (130) having a clamp drive mechanism (133) which includes a linear actuator (133) and a clamp drive linkage having at least one standoff (135) fixed to a clamping plate (125) and extending axially between the clamping plate and the actuator. The actuator moves the at least one standoff axially to selectively engage the pipette body clamping mechanism.

Abstract: A pipetting head for a liquid dispensing apparatus is provided. The pipetting head has a pipette tip connection mechanism and a plunger clamping mechanism having a plurality of mounts for holding the plungers of the array of pipettes during use, a plurality of clamping rods, each extending inside one of the mounts, and a clamping drive mechanism operable to drive relative movement between the mounts and the clamping rods to selectively engage the clamping mechanism. The mounts each have a radially extending feature configured to form one half of a snap-fit connection. The clamping region of each of the clamping rods is axially adjacent to the radially extending feature of its associated mount when in a clamping position, and is axially offset from the radially extending feature of its associated mount when in the release position. The clamping rod prevents the snap-fit connection with the plunger from being released when in the clamping position.

Abstract: A pipetting head for a liquid dispensing apparatus is provided. The pipetting head has a pipette tip clamping mechanism and a plunger clamping mechanism. The pipette tip clamping mechanism and the plunger clamping mechanism each include a mounting plate having a plurality of mounts, a clamping plate having a plurality of clamping members each associated with one of the mounts, and a drive mechanism comprising an actuator operable to drive relative movement between the clamping plate and the mounting plate in an axial direction to selectively engage the clamping mechanism. The pipetting head further includes a drive actuator operable to move the plunger clamping mechanism in the axial direction towards or away from the plates of the pipette tip clamping mechanism to aspirate or dispense liquid during use. The drive actuator is configured to operate independently of the pipette tip clamping drive mechanism and the plunger clamping drive mechanism.

Abstract: The disclosure provides processes for synthesizing compounds for use as CFTR modulators.

Abstract: The disclosure provides processes for synthesizing compounds for use as CFTR modulators.

Abstract: A permanent magnet (PM) motor is provided to facilitate air movement through heat rejection equipment. The PM motor has a body, an upper bearing housing positioned on and extending upwardly from a top surface of the body, a shaft connected to and extending from the upper bearing housing and in communication with a fan, and a lower bearing housing positioned on and extending downwardly from a bottom surface of the body opposite the top surface. The PM motor further includes a mounting assembly having at least three discrete legs disposed on a lower end of the body and extending outwardly from the body.

Abstract: Improved methods for generating a virtual representation of an interior space such as a room are provided. Techniques for capturing and normalizing sets of points for polygon mesh generation that utilize augmented reality toolkits are also described. The improved methods comprise: techniques for generating a polygon mesh that incorporates a projecting extrusion; techniques for generating a polygon mesh that incorporates curved surfaces; and techniques for generating a polygon mesh in real-time.

Abstract: Methods, computer systems and computer programs for generating a virtual representation of an interior space such as a room are provided. Techniques for capturing and normalizing sets of points for polygon mesh generation that utilize augmented reality toolkits are also described.

Abstract: A countertop positionable refrigeration device for countertop controlled storage of cosmetics includes a refrigerator, which is substantially cuboid. The refrigerator comprises a storage compartment having a volume of from 2.50 to 4.00 liters. The refrigerator has a height of between 20.0 and 30.0 cm, a width of between 15.0 and 25.0 cm, and a depth of between 15.0 and 25.0 cm. A plurality of shelves is selectively engageable to the refrigerator so that the shelves are positioned within the storage compartment. Items, such as cosmetics, are stowable upon the shelves and are cooled by the refrigerator.

Abstract: The disclosure provides processes for synthesizing compounds for use as CFTR modulators.

Abstract: The present invention relates to internally profiled variable pitch tubes or pipes made of steel. The terms tube and pipe are used synonymously in the context of this invention. These tubes are used in the petrochemical industry to crack oil, gas and shale feedstocks into simple hydrocarbons such as ethylene and similar products.

Abstract: Implementations relate to systems and methods for generating a user profile based on periodic location fixes. A cellular telephone or other mobile device captures location information via GPS or other capability. A location history can be generated from accumulated location fixes. The location history is then analyzed to detect the user's travel and dwell patterns. That information can be combined with business classification (e.g., SIC, etc.) or Point of Interest (POI) databases to identify a user's likely home, work, or other locations based on dwell-times, time of day, and other parameters. The user's age and gender can potentially be inferred based on types of locations visited, such as school locations. The user profile can be correlated with market segmentation databases to generate a marketing rating, such as a Nielsen or Claritas rating. Advertising, media, or other content can then be tailored to the user's individual location and demographic profiles.

Abstract: A mass spectrometer is disclosed comprising: a first vacuum chamber having an inlet aperture; a second vacuum chamber; a differential pumping aperture separating the vacuum chambers; and an ion guide arranged in the first vacuum chamber for guiding ions from the inlet aperture to and through the differential pumping aperture. The ion guide has a construction for handling high gas loads such that the spectrometer is able to maintain the gas pressure in the first vacuum chamber such that when ions are accelerated therethrough the ions collide with gas and fragment.

Abstract: Implementations relate to systems and methods for generating a user profile based on periodic location fixes. A cellular telephone or other mobile device captures location information via GPS or other capability. A location history can be generated from accumulated location fixes. The location history is then analyzed to detect the user's travel and dwell patterns. That information can be combined with business classification (e.g., SIC, etc.) or Point of Interest (POI) databases to identify a user's likely home, work, or other locations based on dwell-times, time of day, and other parameters. The user's age and gender can potentially be inferred based on types of locations visited, such as school locations. The user profile can be correlated with market segmentation databases to generate a marketing rating, such as a Nielsen or Claritas rating. Advertising, media, or other content can then be tailored to the user's individual location and demographic profiles.

Abstract: A system monitors an event loop executing on a host and determines causes for delays in tasks of the event loop. The system may include circuitry that receives, from an agent of the host, event loop data defining suspend and resume times of the tasks of the event loop executing on the host. The circuitry determines, based on the event loop data, event loop analysis data defining execution times for each of the tasks. The circuitry determines, based on the event loop analysis data, a cause of a delay in a task of the event loop as resulting from at least one of (i) a task delay in execution of the task or (ii) a loop delay in execution of another task of the event loop.

Abstract: A system monitors an event loop executing on a host and determines causes for delays in tasks of the event loop. The system may include circuitry that receives, from an agent of the host, event loop data defining suspend and resume times of the tasks of the event loop executing on the host. The circuitry determines, based on the event loop data, event loop analysis data defining execution times for each of the tasks. The circuitry determines, based on the event loop analysis data, a cause of a delay in a task of the event loop as resulting from at least one of (i) a task delay in execution of the task or (ii) a loop delay in execution of another task of the event loop.

Abstract: Methods, computer systems and computer programs for generating a virtual representation of an interior space such as a room are provided. Techniques for capturing and normalizing sets of points for polygon mesh generation that utilize augmented reality toolkits are also described.

Abstract: An elevator test unit for testing the operation of an elevator system, the test unit including: a first input configured to receive a command input instructing the performance of a test operation in relation to an elevator car associated with the test unit; a first output configured, in response to receipt of the command input at the first input, to cause the generation of a first level request signal or a first simulated level request signal to be sent to a main elevator controller to cause the test operation; a second input configured to receive an indication of whether the test operation occurred successfully; and a second output configured to output a report based on the received indication.

Abstract: Methods, computer systems and computer programs for generating virtual representations of interior spaces such as rooms are provided. Some of the provided methods involve generating a polygon mesh representing the three-dimensional shape of an interior space from multiple sets of points. Techniques for capturing and normalizing the sets of points using augmented reality toolkits are also described. Another provided method involves scaling dimensions of pre-defined graphical models in order to generate refined models.