Abstract: A vacuum assisted suction and irrigation system includes a suction and irrigation wand, an irrigation fluid supply, a vacuum source, and a dual impeller fluid pump. The vacuum source is connected to a suction valve of the suction and irrigation wand to provide suction within the suction and irrigation wand. The irrigation fluid supply is connected to the suction and irrigation wand via the dual impeller fluid pump to supply pressurized irrigation fluid to the suction and irrigation wand. The vacuum source is connected to the fluid pump to pressurize the irrigation fluid being delivered to the suction and irrigation wand.

Abstract: In certain embodiments the present invention provides methods useful in the treatment of glioma, such as glioblastoma, such methods comprising administering to a subject in need thereof a CSF-IR inhibitor together with one or more additional active agents such as IGF-IR inhibitors, PI3K inhibitors, IL4 inhibitors, NFAT inhibitors, and/or Stat6 inhibitors. In certain embodiments the present invention provides pharmaceutical compositions comprising a CSF-IR inhibitor together with one or more of such additional active agents.

Abstract: A dual-diaphragm loudspeaker driver assembly can include a multiple pole magnet structure, and first and second pole piece assemblies can be provided on opposite first and second sides of the multiple pole magnet structure. In an example, each pole piece assembly defines an airgap over a polarity transition region on a respective side of the magnet structure. First and second voice coils can be provided in respective ones of the airgaps, wherein each of the voice coils is coupled to a respective diaphragm assembly, and at least one acoustic tuning port can be configured to provide a damped acoustic communication path between first and opposite second sides of each diaphragm assembly.

Abstract: Devices, methods and systems for removing unwanted tissue from within a patient's vasculature system are provided. Specifically, a laser ablation catheter having a tip with an open, arched-shaped cross section is described. The cross section of the tip enhances the catheter's ability to ablate, separate, and/or dilate the various layers within a patient's vasculature, thereby facilitating the removal undesirable lesions and fibrous tissue within a patient's vasculature.

Abstract: Certain embodiments are directed to device that use a Spectrum Modulated Frequency controlled LED source that strongly attracts a selected target insect or insect population to a trapping and/or killing system to facilitate the capture or disposal of selected genus of flying insects while limiting the attraction of other flying insects.

Abstract: A dual-diaphragm loudspeaker driver assembly can include a multiple pole magnet structure, and first and second pole piece assemblies can be provided on opposite first and second sides of the multiple pole magnet structure. In an example, each pole piece assembly defines an airgap over a polarity transition region on a respective side of the magnet structure. First and second voice coils can be provided in respective ones of the airgaps, wherein each of the voice coils is coupled to a respective diaphragm assembly, and at least one acoustic tuning port can be configured to provide a damped acoustic communication path between first and opposite second sides of each diaphragm assembly.

Abstract: A method for the fail-safe termination of in vivo drug delivery from an implantable drug delivery system, the method comprising: providing an implantable drug delivery system comprising: a housing having a reservoir for containing a drug, and a port for dispensing the drug to a patient; and an emergency deactivation unit disposed between the reservoir and the port, the emergency deactivation unit comprising a composite structure comprising a biocompatible ferromagnetic mesh open to fluid flow and a hydrophobic meltable material, the hydrophobic meltable material comprising at least one hole therein for enabling a fluid to pass through the hydrophobic meltable material; implanting the implantable drug delivery system within a patient; enabling the drug to flow from the reservoir, through the at least one hole in the hydrophobic meltable material and out the port; and when drug flow is to be terminated, applying a magnetic field to the composite structure, such that a current is induced in the ferromagnetic mes

Abstract: Techniques are disclosed for automatic data translation in computing systems. Certain techniques are disclosed herein that enable applications to utilize data in optimal formats specific to each application in an effectively transparent manner, removing the burden to perform data format or type checking, conversions, etc. An automatic data translation module (ADTM) is implemented that automatically translates data as it passes between certain applications. In some embodiments, the ADTM receives a first particular format of data from a first application and automatically/transparently converts the first particular format of data into another representation of the same data, but in a second format utilized by a recipient application.

Abstract: In certain embodiments the present invention provides methods useful in the treatment of glioma, such as glioblastoma, such methods comprising administering to a subject in need thereof a CSF-IR inhibitor together with one or more additional active agents such as IGF-IR inhibitors, PI3K inhibitors, IL4 inhibitors, NFAT inhibitors, and/or Stat6 inhibitors. In certain embodiments the present invention provides pharmaceutical compositions comprising a CSF-IR inhibitor together with one or more of such additional active agents.

Abstract: A base plate for supporting a plurality of interlocking building bricks includes a planar sheet having a top surface and a bottom surface, with a plurality of nodes projecting from the top surface. The plurality of nodes includes a node having a vertical cylindrical wall and a horizontal top wall, the vertical cylindrical wall tapering along its vertical height; the node also having a bevel extending around a circumference of the node at an edge where the vertical cylindrical wall transitions to the horizontal top wall. A method of assembling a composite base plate includes securing two component base plates to one another via a common backing material. A method of printing on a base plate includes applying ultraviolet ink to at least the top surface of the base plate from an ultraviolet light printer, the base plate having a plurality of studs or nodes projecting from the top surface.

Abstract: A base plate for supporting a plurality of interlocking building bricks includes a planar sheet having a top surface and a bottom surface, with a plurality of nodes projecting from the top surface. The plurality of nodes includes a node having a vertical cylindrical wall and a horizontal top wall, the vertical cylindrical wall tapering along its vertical height; the node also having a bevel extending around a circumference of the node at an edge where the vertical cylindrical wall transitions to the horizontal top wall. A method of assembling a composite base plate includes securing two component base plates to one another via a common backing material. A method of printing on a base plate includes applying ultraviolet ink to at least the top surface of the base plate from an ultraviolet light printer, the base plate having a plurality of studs or nodes projecting from the top surface.

Abstract: Techniques are disclosed for automatic data translation in computing systems. Certain techniques are disclosed herein that enable applications to utilize data in optimal formats specific to each application in an effectively transparent manner, removing the burden to perform data format or type checking, conversions, etc. An automatic data translation module (ADTM) is implemented that automatically translates data as it passes between certain applications. In some embodiments, the ADTM receives a first particular format of data from a first application and automatically/transparently converts the first particular format of data into another representation of the same data, but in a second format utilized by a recipient application.

Abstract: A base plate for supporting a plurality of interlocking building bricks includes a planar sheet having a top surface and a bottom surface, with a plurality of nodes projecting from the top surface. The plurality of nodes includes a node having a vertical cylindrical wall and a horizontal top wall, the vertical cylindrical wall tapering along its vertical height; the node also having a bevel extending around a circumference of the node at an edge where the vertical cylindrical wall transitions to the horizontal top wall. A method of assembling a composite base plate includes securing two component base plates to one another via a common backing material. A method of printing on a base plate includes applying ultraviolet ink to at least the top surface of the base plate from an ultraviolet light printer, the base plate having a plurality of studs or nodes projecting from the top surface.

Abstract: An electrical control system having a direct current to direct current regulator receiving a direct current supply input, wherein the regulator outputs a controlled voltage direct current inverter power feed. Included is an inverter in electrical communication with the regulator and receives the controlled voltage direct current inverter power feed, the inverter outputs an alternating current motor power feed to a permanent magnet brushless direct current motor that outputs a shaft rotational speed and a back electromotive force. Also, a control is provided for regulating the controlled voltage direct current inverter power feed based upon criteria utilizing the back electromotive force or an auxiliary motor stator wire loop signal in conjunction with an optional voltage look-up table to substantially make the controlled voltage result in a reduction of a pulse width modulation switching frequency to further smooth and reduce harmonic of the alternating current waveform to increase motor efficiency.

Abstract: Devices, methods and systems for removing unwanted tissue from within a patient's vasculature system are provided. Specifically, a laser ablation catheter having a tip with an open, arched-shaped cross section is described. The cross section of the tip enhances the catheter's ability to ablate, separate, and/or dilate the various layers within a patient's vasculature, thereby facilitating the removal undesirable lesions and fibrous tissue within a patient's vasculature.

Abstract: The present invention may be used to process various foods by pressing them through a receiving receptacle equipped with a processing disk. A body may have a plurality of platforms, frames and support configurations conducive for efficient function. A motor may be in the uppermost section of the body. A switch of choice may activate the motor and set in motion the press process. A ball bearing assembly and press assembly may complete the food press processing function. A receiving receptacle may receive produce for processing by the press plate and push produce through a processing disk, cup or sieve. A set of micro switches may serve to control the electric and mechanical function specific to the task. A press plate with configurations compatible to the disk selected may complete the process when the processed produce is dispensed into a dish or appropriate container.

Abstract: An electrical control system having a direct current to direct current regulator receiving a direct current supply input, wherein the regulator outputs a controlled voltage direct current inverter power feed. Included is an inverter in electrical communication with the regulator and receives the controlled voltage direct current inverter power feed, the inverter outputs an alternating current motor power feed to a permanent magnet brushless direct current motor that outputs a shaft rotational speed and a back electromotive force. Also, a control is provided for regulating the controlled voltage direct current inverter power feed based upon criteria utilizing the back electromotive force or an auxiliary motor stator wire loop signal in conjunction with an optional voltage look-up table to substantially make the controlled voltage result in a reduction of a pulse width modulation switching frequency to further smooth and reduce harmonic of the alternating current waveform to increase motor efficiency.

Abstract: The present invention may be used to process various foods by pressing them through a receiving receptacle equipped with a processing disk. A body may have a plurality of platforms, frames and support configurations conducive for efficient function. A motor may be in the uppermost section of the body. A switch of choice may activate the motor and set in motion the press process. A ball bearing assembly and press assembly may complete the food press processing function. A receiving receptacle may receive produce for processing by the press plate and push produce through a processing disk, cup or sieve. A set of micro switches may serve to control the electric and mechanical function specific to the task. A press plate with configurations compatible to the disk selected may complete the process when the processed produce is dispensed into a dish or appropriate container.

Abstract: A method and device implementing a downloadable operatively connected to a plurality of gaming machines either by a direct communications link or through the use of one or more site controllers or PCs. Each gaming machine and site controller or PC contains two executable spaces, one of which typically contains the software image currently being implemented by the device. The other executable space is designated to receive from the central system a new software image that will be utilized by the device. The central system transfers a new image to be executed, via packet encrypted communications, to a networked device which stores the image in an executable space, while continuing to run the currently designated image. Upon instruction from the central system, the device switches over to the new image, allowing one or more machines to implement a software upgrade on a continuous basis.

Abstract: A method and article of manufacture of treating abnormal biological tissue. The article includes use of electrochemically treated water in combination with a biologically active tissue treatment component, particularly for dermal tissue treatment. The electrochemical treatment method includes exposure of untreated water to halogen containing species, such as hypochlorous and hypobromous acid. The biologically active tissue treatment component can be a cortisone or clobetasol containing media.