Patents by Inventor Robert M. Gale

Robert M. Gale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190167655
    Abstract: A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a subject through skin over an extended period of time are disclosed.
    Type: Application
    Filed: February 8, 2019
    Publication date: June 6, 2019
    Inventors: Subramanian VENKATRAMAN, Shaoling Li, Robert M. Gale, Jane Stepic, William W. Van Osdol
  • Publication number: 20190022026
    Abstract: A method and a daily replacement patch for transdermally administering an opioid for analgesic effect. The patch is applied to a subject to deliver the opioid through the skin. The patch may be replaced daily and over an extended period of time.
    Type: Application
    Filed: September 26, 2018
    Publication date: January 24, 2019
    Inventors: Stephen S. Hwang, Robert M. Gale
  • Publication number: 20180098979
    Abstract: A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a subject through skin over an extended period of time are disclosed.
    Type: Application
    Filed: December 8, 2017
    Publication date: April 12, 2018
    Inventors: SUBRAMANIAN S. VENKATRAMAN, SHAOLING LI, ROBERT M. GALE, JANE STEPIC, WILLIAM W. VAN OSDOL
  • Publication number: 20170105944
    Abstract: A method and a daily replacement patch for transdermal administering an opioid for analgesic effect. The patch is applied to a subject to deliver the opioid through the skin. The patch may be replaced dally and over an extended period of time.
    Type: Application
    Filed: December 23, 2016
    Publication date: April 20, 2017
    Inventors: Stephen S. Hwang, Robert M. Gale
  • Publication number: 20160374955
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Application
    Filed: September 13, 2016
    Publication date: December 29, 2016
    Applicant: ALZA Corporation
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J.N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Publication number: 20160331740
    Abstract: A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a subject through skin over an extended period of time are disclosed.
    Type: Application
    Filed: July 25, 2016
    Publication date: November 17, 2016
    Inventors: SUBRAMANIAN S. VENKATRAMAN, SHAOLING LI, ROBERT M. GALE, JANE STEPIC, WILLIAM W. VAN OSDOL
  • Patent number: 9446004
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: September 20, 2016
    Assignee: ALZA CORPORATION
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J. N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Publication number: 20160058747
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
    Type: Application
    Filed: November 6, 2015
    Publication date: March 3, 2016
    Applicant: ALZA CORPORATION
    Inventor: Robert M. Gale
  • Publication number: 20160051488
    Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Application
    Filed: October 30, 2015
    Publication date: February 25, 2016
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Patent number: 9205059
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: December 8, 2015
    Assignee: ALZA Corporation
    Inventor: Robert M. Gale
  • Patent number: 9205090
    Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: December 8, 2015
    Assignee: ALZA Corporation
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Publication number: 20150246007
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Application
    Filed: May 18, 2015
    Publication date: September 3, 2015
    Applicant: ALZA Corporation
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J.N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Publication number: 20150164820
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
    Type: Application
    Filed: February 23, 2015
    Publication date: June 18, 2015
    Applicant: ALZA Corporation
    Inventor: Robert M. Gale
  • Patent number: 9056061
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: June 16, 2015
    Assignee: ALZA Corporation
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J. N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Patent number: 8999379
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: April 7, 2015
    Assignee: ALZA Corporation
    Inventor: Robert M. Gale
  • Publication number: 20140271799
    Abstract: A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a subject through skin over an extended period of time are disclosed.
    Type: Application
    Filed: June 2, 2014
    Publication date: September 18, 2014
    Applicant: ALZA Corporation
    Inventors: SUBRAMANIAN S. VENKATRAMAN, SHAOLING LI, ROBERT M. GALE, JANE STEPIC, WILLIAM W. VAN OSDOL
  • Publication number: 20140249125
    Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Application
    Filed: May 9, 2014
    Publication date: September 4, 2014
    Applicant: ALZA Corporation
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Publication number: 20140180223
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
    Type: Application
    Filed: February 27, 2014
    Publication date: June 26, 2014
    Applicant: ALZA Corporation
    Inventor: Robert M. Gale
  • Patent number: 8758808
    Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: June 24, 2014
    Assignee: ALZA Corporation
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Patent number: 8747889
    Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: June 10, 2014
    Assignee: Durect Corporation
    Inventors: Robert M. Gale, Thomas M. Stein, Jay Audett, Jane Stepic, Joseph B. Phipps, Michael J. N. Cormier