Patents by Inventor Robert M. Gale

Robert M. Gale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140180223
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
    Type: Application
    Filed: February 27, 2014
    Publication date: June 26, 2014
    Applicant: ALZA Corporation
    Inventor: Robert M. Gale
  • Patent number: 8758808
    Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: June 24, 2014
    Assignee: ALZA Corporation
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Patent number: 8747889
    Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: June 10, 2014
    Assignee: Durect Corporation
    Inventors: Robert M. Gale, Thomas M. Stein, Jay Audett, Jane Stepic, Joseph B. Phipps, Michael J. N. Cormier
  • Patent number: 8663680
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: March 4, 2014
    Assignee: ALZA Corporation
    Inventor: Robert M. Gale
  • Publication number: 20140030316
    Abstract: A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a subject through skin over an extended period of time are disclosed.
    Type: Application
    Filed: July 11, 2013
    Publication date: January 30, 2014
    Applicant: ALZA Corporation
    Inventors: Subramanian S. Venkatraman, Shaoling Li, Robert M. Gale, Jane Stepic, William W. Van Osdol
  • Publication number: 20130251760
    Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.
    Type: Application
    Filed: March 7, 2013
    Publication date: September 26, 2013
    Inventors: Robert M. Gale, Thomas M. Stien, Jay Audett, Jane Stepic, Joseph B. Phipps, Michael JN Cormier
  • Patent number: 8440220
    Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: May 14, 2013
    Assignee: Durect Corporation
    Inventors: Robert M. Gale, Thomas M. Stein, Jay Audett, Jane Stepic, Joseph B. Phipps, Michel J. N. Cormier
  • Patent number: 8383149
    Abstract: A polyacrylate formulation suitable for delivery of drug through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: February 26, 2013
    Assignee: ALZA Corporation
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Publication number: 20120310187
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
    Type: Application
    Filed: December 5, 2011
    Publication date: December 6, 2012
    Applicant: ALZA Corporation
    Inventor: Robert M. Gale
  • Patent number: 8075911
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: December 13, 2011
    Assignee: Alza Corporation
    Inventor: Robert M. Gale
  • Patent number: 7622136
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: November 24, 2009
    Assignee: ALZA Corporation
    Inventor: Robert M. Gale
  • Publication number: 20090258061
    Abstract: A method and a daily replacement patch for transdermally administering an opioid for analgesic effect. The patch is applied to a subject to deliver the opioid through the skin. The patch may be replaced daily and over an extended period of time.
    Type: Application
    Filed: October 15, 2008
    Publication date: October 15, 2009
    Applicant: JOHNSON & JOHNSON
    Inventors: Stephen S. Hwang, Robert M. Gale
  • Publication number: 20090004257
    Abstract: A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a subject through skin over an extended period of time are disclosed.
    Type: Application
    Filed: July 16, 2008
    Publication date: January 1, 2009
    Inventors: Subramanian S. Venkatraman, Shaoling Li, Robert M. Gale, Jane Stepic, William W. Van Osdol
  • Patent number: 7455654
    Abstract: An apparatus for transdermally delivering a nicotine-based agent to a tobacco or nicotine user comprising a microprojection member having a plurality of microprojections that are adapted to pierce the stratum corneum of the tobacco user, the microprojection member having a biocompatible coating disposed thereon that includes a nicotine-based agent.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: November 25, 2008
    Assignee: Alza Corporation
    Inventors: Michel J. N. Cormier, Robert M. Gale, Andrew G. Scott
  • Patent number: 7323191
    Abstract: Composition of matter for application to a body surface or membrane to administer warfarin by permeation through the body surface or membrane, the composition comprising warfarin to be administered, at a therapeutically effective rate, alone or in combination with a permeation enhancer or mixture. Also disclosed are drug delivery devices containing the warfarin or warfarin and enhancer composition and methods for the transdermal administration of the warfarin and warfarin/enhancer composition.
    Type: Grant
    Filed: July 27, 2004
    Date of Patent: January 29, 2008
    Assignee: Alza Corporation
    Inventor: Robert M. Gale
  • Patent number: 7011844
    Abstract: Composition of matter for application to a body surface or membrane to administer fluoxetine by permeation through the body surface or membrane, the composition comprising fluoxetine to be administered, at a therapeutically effective rate, alone or in combination with a permeation enhancer or mixture. A preferred embodiment is directed to the transdermal administration of fluoxetine at reduced skin irritation levels wherein fluoxetine, preferably provided as fluoxetine acetate, is coadministered with a corticosteroid such as hydrocortisone. Also disclosed are drug delivery devices containing the fluoxetine or fluoxetine and enhancer composition and methods for the transdermal administration of the fluoxetine and fluoxetine/enhancer composition.
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: March 14, 2006
    Assignee: Alza Corporation
    Inventors: Robert M. Gale, Melinda K. Nelson, Michel J. N. Cormier, Suneel K. Gupta, Patricia S. Campbell
  • Publication number: 20040234585
    Abstract: A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.
    Type: Application
    Filed: June 18, 2004
    Publication date: November 25, 2004
    Inventor: Robert M. Gale
  • Publication number: 20040213832
    Abstract: A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a subject through skin over an extended period of time are disclosed.
    Type: Application
    Filed: May 21, 2004
    Publication date: October 28, 2004
    Inventors: Subramanian S. Venkatraman, Shaoling Li, Robert M. Gale, Jane Stepic, William W. Van Osdol
  • Publication number: 20040013716
    Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.
    Type: Application
    Filed: April 22, 2003
    Publication date: January 22, 2004
    Inventors: Robert M. Gale, Thomas M. Stein, Jay Audett, Jane Stepic, Joseph B. Phipps, Michel J.N. Cormier
  • Patent number: 6660295
    Abstract: This invention relates to the field of transdermal drug delivery devices and more particularly to improved storage stability thereof. The invention comprises providing a transdermal drug delivery device with a non-occlusive backing or release liner in combination with a degradation protectant such as a desiccant or oxygen scavenger within the sealed pouch containing the device. The combination of the present invention provides increased shelf-life of these devices.
    Type: Grant
    Filed: September 29, 1998
    Date of Patent: December 9, 2003
    Assignee: Alza Corporation
    Inventors: Tyler Watanabe, Robert M. Gale