Abstract: Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.

Abstract: A bollard apparatus for use as a vehicle barrier includes: a plurality of bollard members; a plurality of separate foot members adapted for ground engagement by placement upon or embedment within a surface, one or more of which is attached to at least one bollard member upstanding therefrom, wherein at least one foot member includes: a front edge; a rear edge; at least one lateral edge which opposes a corresponding lateral edge of a neighbouring foot member, wherein at least one lateral edge extends between the front and rear edges and is non-planar so as to include: a first edge part; and, a second edge part that is laterally offset from the first edge part, wherein the bollard apparatus further includes a coupling assembly which couples the foot member to the neighbouring foot member, wherein the coupling assembly is attached to the lateral edge.

Abstract: An article having a retroreflective marking and non-retroreflective, traditional marking is provided. The article presents as having a first design when under common overhead or environmental lighting, and having a second different design when the retroreflective marking is illuminated with a direct light, reflecting the light back to its source to cause an illuminated appearance.

Abstract: Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.

Abstract: A virtual-immersion computer that provides webpages to facilitate virtual immersion. The system uses a media-streamer computer processor for broadcasting media comprising a simulation-video stream, an audio stream, a radio-transmission-stream. The media is structured within a web frame of webpages by the processor and an audio frame, a picture frame, and/or a video with audio frame.

Abstract: Sensors, including time-of-flight sensors, may be used to detect objects in an environment. In an example, a vehicle may include a time-of-flight sensor that images objects around the vehicle, e.g., so the vehicle can navigate relative to the objects. Sensor data generated by the time-of-flight sensor can be impacted by glare. In some examples, corrected data is generated by quantifying glare. A glare region including pixels that are not associated with an object in a range of the time-of-flight sensor may provide glare intensity and glare depth values used to quantify the glare. The glare intensity and glare depth may be used to correct measured data.

Abstract: A bat swing training device has a base assembly, an arm assembly adjustably connected to the base assembly, and a suction assembly that extends through and out of the arm assembly to hold a ball in a stationary position. The suction assembly includes a coil hose connected to a pump, and an upper hose connected to the coil hose at one end, and removably connected to a nozzle assembly at an opposite end.

Abstract: A method of reducing fuel consumption in a machine with an internal combustion engine. The machine has a hybrid mode in which the engine is used for simultaneous ground propulsion via a torque convertor and hydraulic implement propulsion via a hydraulic pump. The engine controller uses a first engine map that defines primary operating constraints. The method comprises: obtaining an initial torque limit from a torque limit profile providing operating constraints that fall within the primary operating constraints. The method further comprises: implementing a torque limit that corresponds to the initial torque limit value such that in an event that a torque demand exceeds the torque limit then the engine speed will drop below the desired engine speed. The method further comprises, in an event that torque converter speed ratio between engine and ground propulsion drops below a speed ratio threshold, removing the torque limit profile and reverting to primary operating constraints.

Abstract: A baseball swing training device has a base, a support member adjustably connected to the base, and a suction assembly disposed in the base that extends through and out of the support member to hold a ball in a stationary position. The suction assembly includes a coil vacuum hose disposed within the support member, and connected to a vacuum pump assembly, and an elongated hose connected to the coil vacuum hose at one end, and removeably connected to a suction nozzle at an opposite end.

Abstract: Sensors, including time-of-flight sensors, may be used to detect objects in an environment. In an example, a vehicle may include a time-of-flight sensor that images objects around the vehicle, e.g., so the vehicle can navigate relative to the objects. The sensor may generate first image data at a first configuration and second image data at a second configuration. The first image data and the second image data may be combined to provide disambiguated depth and improved intensity values for imaging the environment. In some examples, the first and second configurations may have different modulation frequencies, different integration times, and/or different illumination intensities. In some examples, configurations may be dynamically altered based on depth and/or intensity information of a previous frame.

Abstract: A spray head adapted for connection to a supply of fluid. The head includes a body to receive the supply of fluid and a number of conical mixing volumes, in fluid connection with the body and supply of fluid, each conical mixing volume having an outlet. Each conical mixing volume includes at least one first inlet for a flow of fluid into the conical mixing volume at an angle to a conical axis thereof, and at least one second inlet for a flow of fluid into the conical mixing volume substantially parallel to the conical axis. There is a valve disposed upstream of the conical mixing volumes, the valve adapted to divide and vary the supply of fluid flow between the at least one first inlet and the at least one second inlet, which in turn varies the output of the fluid from the outlet of the conical mixing volumes.

Abstract: A labeling device for a syringe that includes a first labeling subsystem adapted to print a first label having machine readable information and a second labeling subsystem adapted to print a second label having human readable information is disclosed. The first labeling subsystem includes a label applicator adapted to automatically apply the first label to a portion of the syringe. The first labeling subsystem includes a syringe clamp assembly that securely holds the syringe while the label applicator automatically applies a first label to the syringe. The second labeling subsystem includes a removal device adapted to automatically remove a backing material from the second label.

Abstract: Sensors, including time-of-flight sensors, may be used to detect objects in an environment. In an example, a vehicle may include a time-of-flight sensor that images objects around the vehicle, e.g., so the vehicle can navigate relative to the objects. The sensor may generate first image data at a first configuration and second image data at a second configuration. The first image data and the second image data may be combined to provide disambiguated depth and improved intensity values for imaging the environment. In some examples, the first and second configurations may have different modulation frequencies, different integration times, and/or different illumination intensities. In some examples, configurations may be dynamically altered based on depth and/or intensity information of a previous frame.

Abstract: Disclosed are compounds of formulae: (I), and (II) and pharmaceutically acceptable salts thereof, wherein the variables, R, R1, R2, R3, R21, R22, R23, R34, R37, R33, R39, D, Q, Y, X, X1, X3, and X4 are defined herein. These compounds are useful for treating Gram-negative bacteria infections.

Abstract: A system that includes: a gas turbine having a combustion system; a control system operably connected to the gas turbine for controlling an operation thereof; and a combustion auto-tuner, which is communicatively linked to the control system, that includes an optimization system having an empirical model of the combustion system and an optimizer; sensors configured to measure the inputs and outputs of the combustion system; a hardware processor; and machine-readable storage medium on which is stored instructions that cause the hardware processor to execute a tuning process for tuning the operation of the combustion system. The tuning process includes the steps of: receiving current measurements from the sensors for the inputs and outputs; given the current measurements received from the sensors, using the optimization system to calculate an optimized control solution for the combustion system; and communicating the optimized control solution to the control system.

Abstract: A system that includes: a gas turbine having a combustion system; a control system operably connected to the gas turbine for controlling an operation thereof; and a combustion auto-tuner, which is communicatively linked to the control system, that includes an optimization system having an empirical model of the combustion system and an optimizer; sensors configured to measure the inputs and outputs of the combustion system; a hardware processor; and machine-readable storage medium on which is stored instructions that cause the hardware processor to execute a tuning process for tuning the operation of the combustion system. The tuning process includes the steps of: receiving current measurements from the sensors for the inputs and outputs; given the current measurements received from the sensors, using the optimization system to calculate an optimized control solution for the combustion system; and communicating the optimized control solution to the control system.

Abstract: Barriers, such as vehicle impact barriers for placing upon an existing surface such as a road surface, or a paved surface, or a pedestrian surface. Surface-mountable and removable barriers are described for use as vehicle impact barriers. Such barriers may be employed for rapid deployment in a street, causeway or other route.

Abstract: Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.

Abstract: Systems, apparatuses and methods are provided herein for alerting customers to product temperature compliance during delivery whereby a retail product intended to be maintained below one or more temperature threshold values through a supply chain delivery process is identified, a temperature threshold value of the retail product is determined, an irreversible thermochromic indicator having an activation temperature that corresponds to the temperature threshold value of the retail product is identified, the thermochromic indicator is affixed to the retail product prior to commencing the supply chain delivery process, and verification, via a user interface, is obtained from a customer receiving the retail product that the thermochromic indicator is in its inactivated state.

Abstract: Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R1, R2, R3, R4, R5, R6, R7, R11, R12, R13, R14, R15, R16, R17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.